DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ tchasovnikarova-2015-1 in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. DIP original experiment: DIP-266274X Science (New York, N.Y.) 2015 IMEx GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells. Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. Only protein-protein interactions imex curation tchasovnikarova-2015-2 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. DIP original experiment: DIP-266268X Science (New York, N.Y.) 2015 IMEx GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells. Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. Only protein-protein interactions imex curation tchasovnikarova-2015-3 in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. DIP original experiment: DIP-266273X Science (New York, N.Y.) 2015 IMEx GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells. Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. Only protein-protein interactions imex curation tchasovnikarova-2015-4 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. DIP original experiment: DIP-266271X Science (New York, N.Y.) 2015 IMEx GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells. Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. Only protein-protein interactions imex curation tchasovnikarova-2015-5 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. DIP original experiment: DIP-266269X Science (New York, N.Y.) 2015 IMEx GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells. Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. Only protein-protein interactions imex curation tchasovnikarova-2015-6 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. DIP original experiment: DIP-266270X Science (New York, N.Y.) 2015 IMEx GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells. Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. Only protein-protein interactions imex curation tchasovnikarova-2015-7 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip de novo protein sequence de novo protein sequencing by mass spectrometry de novo protein sequence Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. DIP original experiment: DIP-266272X Science (New York, N.Y.) 2015 IMEx GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells. Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. Only protein-protein interactions imex curation tchasovnikarova-2015-8 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. DIP original experiment: DIP-266275X Science (New York, N.Y.) 2015 IMEx GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells. Tchasovnikarova IA., Timms RT., Matheson NJ., Wals K., Antrobus R., Göttgens B., Dougan G., Dawson MA., Lehner PJ. Only protein-protein interactions imex curation cbx5_human Chromobox protein homolog 5 CBX5 Heterochromatin protein 1 homolog alpha Antigen p25 HP1A protein protein human Homo sapiens Human MGKKTKRTADSSSSEDEEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKKMKEGENNKPREKSESNKRKSNFSNSADDIKSKKKREQSNDIARGFERGLEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKCPQIVIAFYEERLTWHAYPEDAENKEKETAKS h3k9-2 Histone H3 N-terminal Peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) ARTKQTARKSTGGKAPRKQLA mpp8_human M-phase phosphoprotein 8 MPP8 Two hybrid-associated protein 3 with RanBPM MPHOSPH8 protein protein human Homo sapiens Human MEQVAEGARVTAVPVSAADSTEELAEVEEGVGVVGEDNDAAARGAEAFGDSEEDGEDVFEVEKILDMKTEGGKVLYKVRWKGYTSDDDTWEPEIHLEDCKEVLLEFRKKIAENKAKAVRKDIQRLSLNNDIFEANSDSDQQSETKEDTSPKKKKKKLRQREEKSPDDLKKKKAKAGKLKDKSKPDLESSLESLVFDLRTKKRISEAKEELKESKKPKKDEVKETKELKKVKKGEIRDLKTKTREDPKENRKTKKEKFVESQVESESSVLNDSPFPEDDSEGLHSDSREEKQNTKSARERAGQDMGLEHGFEKPLDSAMSAEEDTDVRGRRKKKTPRKAEDTRENRKLENKNAFLEKKTVPKKQRNQDRSKSAAELEKLMPVSAQTPKGRRLSGEERGLWSTDSAEEDKETKRNESKEKYQKRHDSDKEEKGRKEPKGLKTLKEIRNAFDLFKLTPEEKNDVSENNRKREEIPLDFKTIDDHKTKENKQSLKERRNTRDETDTWAYIAAEGDQEVLDSVCQADENSDGRQQILSLGMDLQLEWMKLEDFQKHLDGKDENFAATDAIPSNVLRDAVKNGDYITVKVALNSNEEYNLDQEDSSGMTLVMLAAAGGQDDLLRLLITKGAKVNGRQKNGTTALIHAAEKNFLTTVAILLEAGAFVNVQQSNGETALMKACKRGNSDIVRLVIECGADCNILSKHQNSALHFAKQSNNVLVYDLLKNHLETLSRVAEETIKDYFEARLALLEPVFPIACHRLCEGPDFSTDFNYKPPQNIPEGSGILLFIFHANFLGKEVIARLCGPCSVQAVVLNDKFQLPVFLDSHFVYSFSPVAGPNKLFIRLTEAPSAKVKLLIGAYRVQLQ tasor_human Protein TASOR TASOR C3orf63 CTCL tumor antigen se89-1 FAM208A KIAA1105 Retinoblastoma-associated protein RAP140 Transgene activation suppressor protein protein protein human Homo sapiens Human MATAVETEACQPTDASWESGGGGDDEMKQALPELESSQQNGGGGGLNIAEPSGGAGREENAGAEAAQSLSHEQPQDSSEAGAAALPRGPEEPERPVRRSFQIPRKSREKKALFQPLTPGSREFEDVVNILHSSYLEPTSVTNFNYRRACLVHNELLEKEFTEKRRELKFDGRLDKELSESYAFLMVDRYQVQTICEKGLHVGQSKITILGSPSMGVYLSRYADLLQANPLDTGAMGDVVIFKIMKGKIKSIYDPMGVKSLESMLNKSALDPTPKHECHVSKNANRITSLLAYRAYELTQYYFYEYGFDELRRRPRHVCPYAVVSFTYKDDIQTPKFVPSSRSNSFNTDRNIDKYNYTLWKGQLLNKGKLLCYISLRSATRAFLPIKLPEKLDVETVMSIDHLKQKIPPALFYKETYLGPNEVLKNGMYCSLYEVVEKTRIGSNMESLLQKLDREKLVLVKPLGDRGYLFLLSPYQMVPPYEYQTAKSRVLHALFLFQEPRSIVTSQKGSTNAAPQERHESMPDVLKIAQFLQFSLIQCRKEFKNISAINFHSVVEKYVSEFFKRGFGSGKREFIMFPYDSRLDDKKFLYSAPRNKSHIDTCLHAYIFRPEVYQLPICKLKELFEENRKLQQFSPLSDYEGQEEEMNGTKMKFGKRNNSRGEAIISGKQRSSHSLDYDKDRVKELINLIQCRKKSVGGDSDTEDMRSKTVLKRKLEDLPENMRKLAKTSNLSENCHLYEESPQPIGSLGHDADLRRQQQDTCNSGIADIHRLFNWLSETLANARHSDASLTDTVNKALGLSTDDAYEELRQKHEYELNSTPDKKDYEQPTCAKVENAQFKGTQSLLLEVDATSKYSVAISTSEVGTDHKLHLKEDPNLISVNNFEDCSLCPSVPIEHGFRRQQSKSNNVEETEIHWKLIPITGGNARSPEDQLGKHGEKQTPGMKSPEEQLVCVPPQEAFPNDPRVINRQRSSDYQFPSSPFTDTLKGTTEDDVLTGQVEEQCVPAAEAEPPAVSETTERTVLGEYNLFSRKIEEILKQKNVSYVSTVSTPIFSTQEKMKRLSEFIYSKTSKAGVQEFVDGLHEKLNTIIIKASAKGGNLPPVSPNDSGAKIASNPLERHVIPVSSSDFNNKHLLEPLCSDPLKDTNSDEQHSTSALTEVEMNQPQHATELMVTSDHIVPGDMAREPVEETTKSPSDVNISAQPALSNFISQLEPEVFNSLVKIMKDVQKNTVKFYIHEEEESVLCKEIKEYLIKLGNTECHPEQFLERRSKLDKLLIIIQNEDIAGFIHKIPGLVTLKKLPCVSFAGVDSLDDVKNHTYNELFVSGGFIVSDESILNPEVVTVENLKNFLTFLEELSTPEGKWQWKVHCKFQKKLKELGRLNAKALSLLTLLNVYQKKHLVEILSYHNCDSQTRNAPELDCLIRLQAQNIQQRHIVFLTEKNIKMLSSYTDNGIVVATAEDFMQNFKNLVGYHNSITEENLPQLGANENLESQSALLENDEKDEEDMSLDSGDEISHIEVCSNFHSEIWEKETKGSRGTDQKKNTQIELQSSPDVQNSLLEDKTYLDSEERTSIDIVCSEGENSNSTEQDSYSNFQVYHSQLNMSHQFSHFNVLTHQTFLGTPYALSSSQSQENENYFLSAYTESLDRDKSPPPLSWGKSDSSRPYSQEK setb1_human Histone-lysine N-methyltransferase SETDB1 SETDB1 KIAA0067 KMT1E SET domain bifurcated 1 ERG-associated protein with SET domain Histone H3-K9 methyltransferase 4 Lysine N-methyltransferase 1E ESET protein protein human Homo sapiens Human MSSLPGCIGLDAATATVESEEIAELQQAVVEELGISMEELRHFIDEELEKMDCVQQRKKQLAELETWVIQKESEVAHVDQLFDDASRAVTNCESLVKDFYSKLGLQYRDSSSEDESSRPTEIIEIPDEDDDVLSIDSGDAGSRTPKDQKLREAMAALRKSAQDVQKFMDAVNKKSSSQDLHKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPGKKYKVKFDNKGKSLLSGNHIAYDYHPPADKLYVGSRVVAKYKDGNQVWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRPNMGAVRSKGPVVQYTQDLTGTGTQFKPVEPPQPTAPPAPPFPPAPPLSPQAGDSDLESQLAQSRKQVAKKSTSFRPGSVGSGHSSPTSPALSENVSGGKPGINQTYRSPLGSTASAPAPSALPAPPAPPVFHGMLERAPAEPSYRAPMEKLFYLPHVCSYTCLSRVRPMRNEQYRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDAPCSSDSSGVDLKDQEDGNSGTEDPEESNDDSSDDNFCKDEDFSTSSVWRSYATRRQTRGQKENGLSETTSKDSHPPDLGPPHIPVPPSIPVGGCNPPSSEETPKNKVASWLSCNSVSEGGFADSDSHSSFKTNEGGEGRAGGSRMEAEKASTSGLGIKDEGDIKQAKKEDTDDRNKMSVVTESSRNYGYNPSPVKPEGLRRPPSKTSMHQSRRLMASAQSNPDDVLTLSSSTESEGESGTSRKPTAGQTSATAVDSDDIQTISSGSEGDDFEDKKNMTGPMKRQVAVKSTRGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL pphln_human Periphilin-1 Gastric cancer antigen Ga50 HSPC206 HSPC232 PPHLN1 CDC7 expression repressor protein protein human Homo sapiens Human MWSEGRYEYERIPRERAPPRSHPSDGYNRLVNIVPKKPPLLDRPGEGSYNRYYSHVDYRDYDEGRSFSHDRRSGPPHRGDESGYRWTRDDHSASRQPEYRDMRDGFRRKSFYSSHYARERSPYKRDNTFFRESPVGRKDSPHSRSGSSVSSRSYSPERSKSYSFHQSQHRKSVRPGASYKRQNEGNPERDKERPVQSLKTSRDTSPSSGSAVSSSKVLDKPSRLTEKELAEAASKWAAEKLEKSDESNLPEISEYEAGSTAPLFTDQPEEPESNTTHGIELFEDSQLTTRSKAIASKTKEIEQVYRQDCETFGMVVKMLIEKDPSLEKSIQFALRQNLHEIESAGQTWQQVPPVRNTEMDHDGTPENEGEETAQSAPQPPQAPQPLQPRKKRVRRTTQLRRTTGAPDITWGMLKKTTQEAERILLRTQTPFTPENLFLAMLSVVHCNSRKDVKPENKQ h3(121)-cbx5-1 3279104 N/A 3279112 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3279113 unspecified role unspecified role bait bait K9me2 K9me2 n6me2lys N6,N6-dimethyl-L-lysine (2S)-2-amino-6-(dimethylamino)hexanoic acid MOD_RES N6,N6-dimethyllysine N(zeta)-dimethyllysine N6,N6-dimethyl-L-lysine N6,N6-dimethylated L-lysine epsilon-dimethyllysine lysine derivative Lys(y) Dimethyl N6Me2Lys di-Methylation dimethylk certain certain sequence position certain certain certain sequence position certain false K9me3 K9me3 n6me3+lys N6,N6,N6-trimethyl-L-lysine (5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium 2-amino-6-(trimethylammonio)hexanoic acid 5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium MOD_RES N6,N6,N6-trimethyllysine N(zeta)-trimethyllysine N6,N6,N6-trimethyl-L-lysine N6,N6,N6-trimethylated L-lysine N6,N6,N6-trimethyllysin-N6-ium N6,N6,N6-trimethyllysine cation epsilon-trimethyllysine N-trimethylation (of lysine) N6Me3+Lys Trimethyl tri-Methylation certain certain sequence position certain certain certain sequence position certain false Biotin-tag Biotin-tag biotin tag biotin tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false in vitro In vitro physical association physical association false false false fam208a-mphosph8-1 3279105 N/A 3279114 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3279115 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false h3(121)-cbx5-2 3279106 N/A 3279112 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3279113 unspecified role unspecified role bait bait K9me2 K9me2 n6me2lys N6,N6-dimethyl-L-lysine (2S)-2-amino-6-(dimethylamino)hexanoic acid MOD_RES N6,N6-dimethyllysine N(zeta)-dimethyllysine N6,N6-dimethyl-L-lysine N6,N6-dimethylated L-lysine epsilon-dimethyllysine lysine derivative Lys(y) Dimethyl N6Me2Lys di-Methylation dimethylk certain certain sequence position certain certain certain sequence position certain false K9me3 K9me3 n6me3+lys N6,N6,N6-trimethyl-L-lysine (5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium 2-amino-6-(trimethylammonio)hexanoic acid 5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium MOD_RES N6,N6,N6-trimethyllysine N(zeta)-trimethyllysine N6,N6,N6-trimethyl-L-lysine N6,N6,N6-trimethylated L-lysine N6,N6,N6-trimethyllysin-N6-ium N6,N6,N6-trimethyllysine cation epsilon-trimethyllysine N-trimethylation (of lysine) N6Me3+Lys Trimethyl tri-Methylation certain certain sequence position certain certain certain sequence position certain false Biotin-tag Biotin-tag biotin tag biotin tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false in vitro In vitro N/A 3279114 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3279115 unspecified role unspecified role prey prey human Homo sapiens Human association association false false false setdb1-fam208a-1 3279107 N/A 3279116 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3279114 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3279115 unspecified role unspecified role prey prey human Homo sapiens Human association association false false false mphosph8-fam208a-1 3279108 N/A 3279114 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3279115 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false pphln1-fam208a-1 3279109 N/A 3279117 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3279114 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3279115 unspecified role unspecified role prey prey human Homo sapiens Human association association false false false fam208a-mphosph8-2 3279110 N/A 3279117 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3279114 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3279115 unspecified role unspecified role bait bait human Homo sapiens Human association association false false false h3(121)-mphosph8-1 3279111 N/A 3279113 unspecified role unspecified role bait bait K9me1 K9me1 me1lys monomethylated L-lysine Me1Lys Methyl Methylation methylk certain certain sequence position certain certain certain sequence position certain false Biotin-tag Biotin-tag biotin tag biotin tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false in vitro In vitro N/A 3279114 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false