DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ lewis-2015-1 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Lewis HD., Liddle J., Coote JE., Atkinson SJ., Barker MD., Bax BD., Bicker KL., Bingham RP., Campbell M., Chen YH., Chung CW., Craggs PD., Davis RP., Eberhard D., Joberty G., Lind KE., Locke K., Maller C., Martinod K., Patten C., Polyakova O., Rise CE., Rüdiger M., Sheppard RJ., Slade DJ., Thomas P., Thorpe J., Yao G., Drewes G., Wagner DD., Thompson PR., Prinjha RK., Wilson DM. DIP original experiment: DIP-266207X Nature chemical biology 2015 IMEx Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Lewis HD., Liddle J., Coote JE., Atkinson SJ., Barker MD., Bax BD., Bicker KL., Bingham RP., Campbell M., Chen YH., Chung CW., Craggs PD., Davis RP., Eberhard D., Joberty G., Lind KE., Locke K., Maller C., Martinod K., Patten C., Polyakova O., Rise CE., Rüdiger M., Sheppard RJ., Slade DJ., Thomas P., Thorpe J., Yao G., Drewes G., Wagner DD., Thompson PR., Prinjha RK., Wilson DM. Only protein-protein interactions imex curation padi4_human Protein-arginine deiminase type-4 PADI4 PADI5 PDI5 Protein-arginine deiminase type IV Peptidylarginine deiminase IV HL-60 PAD PAD4 protein protein human Homo sapiens Human MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKKKSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCADITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDMSLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMVPGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTPNTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAPHKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRGKEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVPAPDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNSFVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPKPFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWNMVP padi4-1 3274839 N/A 3274840 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction false false false