DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ wang-2014-44 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Wang Y., Bu F., Royer C., Serres S., Larkin JR., Soto MS., Sibson NR., Salter V., Fritzsche F., Turnquist C., Koch S., Zak J., Zhong S., Wu G., Liang A., Olofsen PA., Moch H., Hancock DC., Downward J., Goldin RD., Zhao J., Tong X., Guo Y., Lu X. DIP original experiment: DIP-262428X Nature cell biology 2014 IMEx ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1. Wang Y., Bu F., Royer C., Serres S., Larkin JR., Soto MS., Sibson NR., Salter V., Fritzsche F., Turnquist C., Koch S., Zak J., Zhong S., Wu G., Liang A., Olofsen PA., Moch H., Hancock DC., Downward J., Goldin RD., Zhao J., Tong X., Guo Y., Lu X. Only protein-protein interactions imex curation wang-2014-45 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Wang Y., Bu F., Royer C., Serres S., Larkin JR., Soto MS., Sibson NR., Salter V., Fritzsche F., Turnquist C., Koch S., Zak J., Zhong S., Wu G., Liang A., Olofsen PA., Moch H., Hancock DC., Downward J., Goldin RD., Zhao J., Tong X., Guo Y., Lu X. DIP original experiment: DIP-262431X Nature cell biology 2014 IMEx ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1. Wang Y., Bu F., Royer C., Serres S., Larkin JR., Soto MS., Sibson NR., Salter V., Fritzsche F., Turnquist C., Koch S., Zak J., Zhong S., Wu G., Liang A., Olofsen PA., Moch H., Hancock DC., Downward J., Goldin RD., Zhao J., Tong X., Guo Y., Lu X. Only protein-protein interactions imex curation wang-2014-46 in vitro In vitro anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Wang Y., Bu F., Royer C., Serres S., Larkin JR., Soto MS., Sibson NR., Salter V., Fritzsche F., Turnquist C., Koch S., Zak J., Zhong S., Wu G., Liang A., Olofsen PA., Moch H., Hancock DC., Downward J., Goldin RD., Zhao J., Tong X., Guo Y., Lu X. DIP original experiment: DIP-262433X Nature cell biology 2014 IMEx ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1. Wang Y., Bu F., Royer C., Serres S., Larkin JR., Soto MS., Sibson NR., Salter V., Fritzsche F., Turnquist C., Koch S., Zak J., Zhong S., Wu G., Liang A., Olofsen PA., Moch H., Hancock DC., Downward J., Goldin RD., Zhao J., Tong X., Guo Y., Lu X. Only protein-protein interactions imex curation wang-2014-47 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Wang Y., Bu F., Royer C., Serres S., Larkin JR., Soto MS., Sibson NR., Salter V., Fritzsche F., Turnquist C., Koch S., Zak J., Zhong S., Wu G., Liang A., Olofsen PA., Moch H., Hancock DC., Downward J., Goldin RD., Zhao J., Tong X., Guo Y., Lu X. DIP original experiment: DIP-262429X Nature cell biology 2014 IMEx ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1. Wang Y., Bu F., Royer C., Serres S., Larkin JR., Soto MS., Sibson NR., Salter V., Fritzsche F., Turnquist C., Koch S., Zak J., Zhong S., Wu G., Liang A., Olofsen PA., Moch H., Hancock DC., Downward J., Goldin RD., Zhao J., Tong X., Guo Y., Lu X. Only protein-protein interactions imex curation wang-2014-48 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Wang Y., Bu F., Royer C., Serres S., Larkin JR., Soto MS., Sibson NR., Salter V., Fritzsche F., Turnquist C., Koch S., Zak J., Zhong S., Wu G., Liang A., Olofsen PA., Moch H., Hancock DC., Downward J., Goldin RD., Zhao J., Tong X., Guo Y., Lu X. DIP original experiment: DIP-262432X Nature cell biology 2014 IMEx ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1. Wang Y., Bu F., Royer C., Serres S., Larkin JR., Soto MS., Sibson NR., Salter V., Fritzsche F., Turnquist C., Koch S., Zak J., Zhong S., Wu G., Liang A., Olofsen PA., Moch H., Hancock DC., Downward J., Goldin RD., Zhao J., Tong X., Guo Y., Lu X. Only protein-protein interactions imex curation wang-2014-49 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Wang Y., Bu F., Royer C., Serres S., Larkin JR., Soto MS., Sibson NR., Salter V., Fritzsche F., Turnquist C., Koch S., Zak J., Zhong S., Wu G., Liang A., Olofsen PA., Moch H., Hancock DC., Downward J., Goldin RD., Zhao J., Tong X., Guo Y., Lu X. DIP original experiment: DIP-262430X Nature cell biology 2014 IMEx ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1. Wang Y., Bu F., Royer C., Serres S., Larkin JR., Soto MS., Sibson NR., Salter V., Fritzsche F., Turnquist C., Koch S., Zak J., Zhong S., Wu G., Liang A., Olofsen PA., Moch H., Hancock DC., Downward J., Goldin RD., Zhao J., Tong X., Guo Y., Lu X. Only protein-protein interactions imex curation cadh1_human Cadherin-1 Epithelial cadherin Uvomorulin CAM 120/80 CDH1 CDHE UVO protein protein human Homo sapiens Human MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD ctnb1_human Catenin beta-1 Beta-catenin OK/SW-cl.35 PRO2286 CTNNB1 CTNNB protein protein human Homo sapiens Human MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL aspp2_human Apoptosis-stimulating of p53 protein 2 TP53BP2 ASPP2 BBP Tumor suppressor p53-binding protein 2 Bcl2-binding protein Renal carcinoma antigen NY-REN-51 protein protein human Homo sapiens Human MMPMFLTVYLSNNEQHFTEVPVTPETICRDVVDLCKEPGESDCHLAEVWCGSERPVADNERMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEYRRKENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRPELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENIYSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA pard3_human Partitioning defective 3 homolog PARD3 PAR3 PAR3A Atypical PKC isotype-specific-interacting protein CTCL tumor antigen se2-5 PAR3-alpha protein protein human Homo sapiens Human MKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGESGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSYKKVQDPSYAPPKGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS tp53bp2-cdh1-1 3270781 N/A 3270787 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3270788 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3270789 unspecified role unspecified role bait bait human Homo sapiens Human association association false false false tp53bp2-ctnnb1-1 3270782 N/A 3270789 unspecified role unspecified role bait bait Region 1-360 Region 1-360 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false V5-tag V5-tag v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3270788 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false tp53bp2-ctnnb1-2 3270783 N/A 3270789 unspecified role unspecified role bait bait in vitro In vitro N/A 3270788 unspecified role unspecified role prey prey in vitro In vitro physical association physical association false false false tp53bp2-ctnnb1-3 3270784 N/A 3270788 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3270789 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false tp53bp2-ctnnb1-4 3270785 N/A 3270790 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3270788 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3270789 unspecified role unspecified role bait bait human Homo sapiens Human association association false false false ctnnb1-cdh1-15 3270786 N/A 3270787 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3270788 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false