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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3267176">
                <names>
                    <shortLabel>whicher-2014-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="24965656" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-262110X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-23152" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16110737" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="https://doi.org/10.1038/nature13409" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="562">
                        <names>
                            <shortLabel>ecolx</shortLabel>
                            <fullName>Escherichia coli</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>3d-em</shortLabel>
                        <fullName>3D electron microscopy</fullName>
                        <alias typeAc="MI:1041" type="synonym">3D-EM</alias>
                        <alias typeAc="MI:1041" type="synonym">electron tomog</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0410" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="12160704" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608522" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Whicher JR., Dutta S., Hansen DA., Hale WA., Chemler JA., Dosey AM., Narayan AR., Håkansson K., Sherman DH., Smith JL., Skiniotis G.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-262110X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2014</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Structural rearrangements of a polyketide synthase module during its catalytic cycle.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Whicher JR.,  Dutta S.,  Hansen DA.,  Hale WA.,  Chemler JA.,  Dosey AM.,  Narayan AR.,  Håkansson K.,  Sherman DH.,  Smith JL.,  Skiniotis G.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3267177">
                <names>
                    <shortLabel>pika3_strvz</shortLabel>
                    <fullName>Narbonolide/10-deoxymethynolide synthase PikA3, module 5</fullName>
                    <alias typeAc="MI:0301" type="gene name">pikAIII</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Narbonolide/10-deoxymethynolide synthase PikAIII</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Pikromycin polyketide synthase component PikAIII</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Type I modular polyketide synthase PikAIII</alias>
                    <alias typeAc="MI:0306" type="orf name">BN2537_6637</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9ZGI3" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016039" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006162" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020806" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014030" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014043" version="SP_116"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3F5H" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020841" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014031" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001227" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016035" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036299" version="SP_116"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016747" secondary="acyltransferase activity, transferring groups other than amino-acyl groups" version="SP_116"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006633" secondary="fatty acid biosynthetic process" version="SP_116"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013968" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015083" version="SP_116"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004315" secondary="3-oxoacyl-[acyl-carrier-protein] synthase activity" version="SP_116"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031177" secondary="phosphopantetheine binding" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036736" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016036" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032821" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036291" version="SP_116"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033068" secondary="macrolide biosynthetic process" version="SP_116"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-9023465" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018201" version="SP_116"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009081" version="SP_116"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-61040N"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="54571">
                    <names>
                        <shortLabel>strvz</shortLabel>
                        <fullName>Streptomyces venezuelae</fullName>
                    </names>
                </organism>
                <sequence>MANNEDKLRDYLKRVTAELQQNTRRLREIEGRTHEPVAIVGMACRLPGGVASPEDLWQLVAGDGDAISEFPQDRGWDVEGLYDPDPDASGRTYCRSGGFLHDAGEFDADFFGISPREALAMDPQQRLSLTTAWEAIESAGIDPTALKGSGLGVFVGGWHTGYTSGQTTAVQSPELEGHLVSGAALGFLSGRIAYVLGTDGPALTVDTACSSSLVALHLAVQALRKGECDMALAGGVTVMPNADLFVQFSRQRGLAADGRSKAFATSADGFGPAEGAGVLLVERLSDARRNGHRILAVVRGSAVNQDGASNGLTAPHGPSQQRVIRRALADARLAPGDVDVVEAHGTGTRLGDPIEAQALIATYGQEKSSEQPLRLGALKSNIGHTQAAAGVAGVIKMVQAMRHGLLPKTLHVDEPSDQIDWSAGTVELLTEAVDWPEKQDGGLRRAAVSSFGISGTNAHVVLEEAPAVEDSPAVEPPAGGGVVPWPVSAKTPAALDAQIGQLAAYADGRTDVDPAVAARALVDSRTAMEHRAVAVGDSREALRDALRMPEGLVRGTSSDVGRVAFVFPGQGTQWAGMGAELLDSSPEFAASMAECETALSRYVDWSLEAVVRQEPGAPTLDRVDVVQPVTFAVMVSLAKVWQHHGITPQAVVGHSQGEIAAAYVAGALTLDDAARVVTLRSKSIAAHLAGKGGMISLALDEAAVLKRLSDFDGLSVAAVNGPTATVVSGDPTQIEELARTCEADGVRARIIPVDYASHSRQVEIIEKELAEVLAGLAPQAPHVPFFSTLEGTWITEPVLDGTYWYRNLRHRVGFAPAVETLAVDGFTHFIEVSAHPVLTMTLPETVTGLGTLRREQGGQERLVTSLAEAWANGLTIDWAPILPTATGHHPELPTYAFQTERFWLQSSAPTSAADDWRYRVEWKPLTASGQADLSGRWIVAVGSEPEAELLGALKAAGAEVDVLEAGADDDREALAARLTALTTGDGFTGVVSLLDDLVPQVAWVQALGDAGIKAPLWSVTQGAVSVGRLDTPADPDRAMLWGLGRVVALEHPERWAGLVDLPAQPDAAALAHLVTALSGATGEDQIAIRTTGLHARRLARAPLHGRRPTRDWQPHGTVLITGGTGALGSHAARWMAHHGAEHLLLVSRSGEQAPGATQLTAELTASGARVTIAACDVADPHAMRTLLDAIPAETPLTAVVHTAGAPGGDPLDVTGPEDIARILGAKTSGAEVLDDLLRGTPLDAFVLYSSNAGVWGSGSQGVYAAANAHLDALAARRRARGETATSVAWGLWAGDGMGRGADDAYWQRRGIRPMSPDRALDELAKALSHDETFVAVADVDWERFAPAFTVSRPSLLLDGVPEARQALAAPVGAPAPGDAAVAPTGQSSALAAITALPEPERRPALLTLVRTHAAAVLGHSSPDRVAPGRAFTELGFDSLTAVQLRNQLSTVVGNRLPATTVFDHPTPAALAAHLHEAYLAPAEPAPTDWEGRVRRALAELPLDRLRDAGVLDTVLRLTGIEPEPGSGGSDGGAADPGAEPEASIDDLDAEALIRMALGPRNT</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-23152-1" id="3267178">
                <names>
                    <shortLabel>pikaiii-3</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-197210E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16110748" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-23152-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3267176</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3267179">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16110752" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3267177</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="562">
                                <names>
                                    <shortLabel>ecolx</shortLabel>
                                    <fullName>Escherichia coli</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
