DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ kojima-2014-1 in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Kojima R., Okumura M., Masui S., Kanemura S., Inoue M., Saiki M., Yamaguchi H., Hikima T., Suzuki M., Akiyama S., Inaba K. DIP original experiment: DIP-259680X Structure (London, England : 1993) 2014 IMEx Radically different thioredoxin domain arrangement of ERp46, an efficient disulfide bond introducer of the mammalian PDI family. Kojima R., Okumura M., Masui S., Kanemura S., Inoue M., Saiki M., Yamaguchi H., Hikima T., Suzuki M., Akiyama S., Inaba K. Only protein-protein interactions imex curation kojima-2014-2 in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Kojima R., Okumura M., Masui S., Kanemura S., Inoue M., Saiki M., Yamaguchi H., Hikima T., Suzuki M., Akiyama S., Inaba K. DIP original experiment: DIP-259681X Structure (London, England : 1993) 2014 IMEx Radically different thioredoxin domain arrangement of ERp46, an efficient disulfide bond introducer of the mammalian PDI family. Kojima R., Okumura M., Masui S., Kanemura S., Inoue M., Saiki M., Yamaguchi H., Hikima T., Suzuki M., Akiyama S., Inaba K. Only protein-protein interactions imex curation prdx4_mouse Peroxiredoxin-4 Peroxiredoxin IV Thioredoxin peroxidase AO372 Thioredoxin-dependent peroxide reductase A0372 Antioxidant enzyme AOE372 Thioredoxin-dependent peroxiredoxin 4 Prdx4 protein protein mouse Mus musculus Mouse MEARSKLLDGTTASRRWTRKLVLLLPPLLLFLLRTESLQGLESDERFRTRENECHFYAGGQVYPGEASRVSVADHSLHLSKAKISKPAPYWEGTAVINGEFKELKLTDYRGKYLVFFFYPLDFTFVCPTEIIAFGDRIEEFKSINTEVVACSVDSQFTHLAWINTPRRQGGLGPIRIPLLSDLNHQISKDYGVYLEDSGHTLRGLFIIDDKGVLRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVCPAGWKPGSETIIPDPAGKLKYFDKLN q8nbs9-1 Thioredoxin domain-containing protein 5 TXNDC5 TLP46 Endoplasmic reticulum resident protein 46 Thioredoxin-like protein p46 UNQ364/PRO700 protein protein human Homo sapiens Human MPARPGRLLPLLARPAALTALLLLLLGHGGGGRWGARAQEAAAAAADGPPAADGEDGQDPHSKHLYTADMFTHGIQSAAHFVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFVLSQAKDEL prdx4-txndc5-2 3262589 N/A 3262591 unspecified role unspecified role unspecified role unspecified role Region 244-263 Region 244-263 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false in vitro In vitro N/A 3262592 unspecified role unspecified role unspecified role unspecified role Region 190-298 Region 190-298 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false prdx4-txndc5-3 3262590 N/A 3262591 unspecified role unspecified role unspecified role unspecified role Region 244-263 Region 244-263 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false in vitro In vitro N/A 3262592 unspecified role unspecified role unspecified role unspecified role Region 190-298 Region 190-298 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false