DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ hartkoorn-2014-1 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Hartkoorn RC., Pojer F., Read JA., Gingell H., Neres J., Horlacher OP., Altmann KH., Cole ST. DIP original experiment: DIP-260151X Nature chemical biology 2014 IMEx Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA. Hartkoorn RC., Pojer F., Read JA., Gingell H., Neres J., Horlacher OP., Altmann KH., Cole ST. Only protein-protein interactions imex curation inha_myctu Enoyl-[acyl-carrier-protein] reductase [NADH] inhA FAS-II enoyl-ACP reductase MTCY277.05 Rv1484 NADH-dependent 2-trans-enoyl-ACP reductase protein protein myctu Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) MTGLLDGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRITDRLPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGVVHSIGFMPQTGMGINPFFDAPYADVSKGIHISAYSYASMAKALLPIMNPGGSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSDWLPATTGDIIYADGGAHTQLL F161D6D6A631CA08 inha-1 3260539 N/A 3260540 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction false false false