IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ kim-2013-23 in vitro In vitro anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Kim T., Vidal GS., Djurisic M., William CM., Birnbaum ME., Garcia KC., Hyman BT., Shatz CJ. cshatz@stanford.edu,tkim808@stanford.edu Science (New York, N.Y.) 2013 Only protein-protein interactions imex curation imex curation kim-2013-25 in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Kim T., Vidal GS., Djurisic M., William CM., Birnbaum ME., Garcia KC., Hyman BT., Shatz CJ. cshatz@stanford.edu,tkim808@stanford.edu Science (New York, N.Y.) 2013 Only protein-protein interactions imex curation imex curation kim-2013-21 in vitro In vitro affinity chrom affinity chromatography technology Affinity purification Affinity purification affinity chrom western blot western blot Immuno blot Immuno blot Kim T., Vidal GS., Djurisic M., William CM., Birnbaum ME., Garcia KC., Hyman BT., Shatz CJ. cshatz@stanford.edu,tkim808@stanford.edu Science (New York, N.Y.) 2013 Only protein-protein interactions imex curation imex curation kim-2013-24 in vitro In vitro fluorescence imaging fluorescence microscopy fluorescence imaging immunocytochemistry immunocytochemistry Kim T., Vidal GS., Djurisic M., William CM., Birnbaum ME., Garcia KC., Hyman BT., Shatz CJ. cshatz@stanford.edu,tkim808@stanford.edu Science (New York, N.Y.) 2013 Only protein-protein interactions imex curation imex curation kim-2013-18 in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Kim T., Vidal GS., Djurisic M., William CM., Birnbaum ME., Garcia KC., Hyman BT., Shatz CJ. cshatz@stanford.edu,tkim808@stanford.edu Science (New York, N.Y.) 2013 Only protein-protein interactions imex curation imex curation kim-2013-19 in vitro In vitro electrophoresis electrophoretic mobility-based method electrophoresis western blot western blot Immuno blot Immuno blot Kim T., Vidal GS., Djurisic M., William CM., Birnbaum ME., Garcia KC., Hyman BT., Shatz CJ. cshatz@stanford.edu,tkim808@stanford.edu Science (New York, N.Y.) 2013 Only protein-protein interactions imex curation imex curation kim-2013-20 in vitro In vitro fluorescence imaging fluorescence microscopy fluorescence imaging tag visualisation tag visualisation Kim T., Vidal GS., Djurisic M., William CM., Birnbaum ME., Garcia KC., Hyman BT., Shatz CJ. Bound Amyloid-beta-biotin peptides were visualized with streptavidin-alexa fluorophore or Alkaline phosphatase -streptavidin conjugates. cshatz@stanford.edu,tkim808@stanford.edu Science (New York, N.Y.) 2013 Only protein-protein interactions imex curation imex curation kim-2013-22 mouse-forebrain Mus musculus, forebrain brain_forebrain anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Kim T., Vidal GS., Djurisic M., William CM., Birnbaum ME., Garcia KC., Hyman BT., Shatz CJ. Interactions involving antibodies to Cofilin have not been included due to lack of antibody specificity. Interactions with PP2A, B, or C have not been included due to unknown identity of proteins targetted. cshatz@stanford.edu,tkim808@stanford.edu Science (New York, N.Y.) 2013 Only protein-protein interactions imex curation imex curation p05067-pro_0000000092 Amyloid-beta protein 42 Alzheimer disease amyloid protein Cerebral vascular amyloid peptide APP A4 AD1 ABPP PreA4 Protease nexin-II APPI Amyloid precursor protein Amyloid-beta A4 protein Alzheimer disease amyloid A4 protein homolog Amyloid-beta (A4) precursor protein protein protein human Homo sapiens Human DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA 672 713 lirb3_mouse Leukocyte immunoglobulin-like receptor subfamily B member 3 Lilrb3 Pirb Cell-surface glycoprotein p91 Paired immunoglobulin-like receptor B protein protein mouse Mus musculus Mouse MSCTFTALLRLGLTLSLWIPVLTGSLPKPILRVQPDSVVSRRTKVTFLCEETIGANEYRLYKDGKLYKTVTKNKQKPENKAEFSFSNVDLSNAGQYRCSYSTQYKSSGYSDLLELVVTGHYWTPSLLAQASPVVTSGGYVTLQCESWHNDHKFILTVEGPQKLSWTQDSQYNYSTRKYHALFSVGPVTPNQRWICRCYSYDRNRPYVWSPPSESVELLVSGNLQKPTIKAEPGSVITSKRAMTIWCQGNLDAEVYFLHNEKSQKTQSTQTLQEPGNKGKFFIPSVTLQHAGQYRCYCYGSAGWSQPSDTLELVVTGIYEYYEPRLSVLPSPVVTAGGNMTLHCASDFPYDKFILTKEDKKFGNSLDTEHISSSGQYRALFIIGPTTPTHTGAFRCYGYYKNAPQLWSVPSALQQILISGLSKKPSLLTHQGHILDPGMTLTLQCFSDINYDRFALHKVGGADIMQHSSQQTDTGFSVANFTLGYVSSSTGGQYRCYGAHNLSSEWSASSEPLDILITGQLPLTPSLSVQPNHTVHSGETVSLLCWSMDSVDTFILSKEGSAQQPLRLKSKSHDQQSQAEFSMSAVTSHLSGTYRCYGAQDSSFYLLSSASAPVELTVSGPIETSTPPPTMSMPLGGLHMYLKALIGVSVAFILFLFIFIFILLRRRHRGKFRKDVQKEKDLQLSSGAEEPITRKGELQKRPNPAAATQEESLYASVEDMQTEDGVELNSWTPPEEDPQGETYAQVKPSRLRKAGHVSPSVMSREQLNTEYEQAEEGQGANNQAAESGESQDVTYAQLCSRTLRQGAAASPLSQAGEAPEEPSVYATLAAARPEAVPKDMEQ rtn4_rat Reticulon-4 Rtn4 Nogo Neurite outgrowth inhibitor Foocen Glut4 vesicle 20 kDa protein protein protein rat Rattus norvegicus (Rat) Rat MEDIDQSSLVSSSTDSPPRPPPAFKYQFVTEPEDEEDEEEEEDEEEDDEDLEELEVLERKPAAGLSAAAVPPAAAAPLLDFSSDSVPPAPRGPLPAAPPAAPERQPSWERSPAAPAPSLPPAAAVLPSKLPEDDEPPARPPPPPPAGASPLAEPAAPPSTPAAPKRRGSGSVDETLFALPAASEPVIPSSAEKIMDLMEQPGNTVSSGQEDFPSVLLETAASLPSLSPLSTVSFKEHGYLGNLSAVSSSEGTIEETLNEASKELPERATNPFVNRDLAEFSELEYSEMGSSFKGSPKGESAILVENTKEEVIVRSKDKEDLVCSAALHSPQESPVGKEDRVVSPEKTMDIFNEMQMSVVAPVREEYADFKPFEQAWEVKDTYEGSRDVLAARANVESKVDRKCLEDSLEQKSLGKDSEGRNEDASFPSTPEPVKDSSRAYITCASFTSATESTTANTFPLLEDHTSENKTDEKKIEERKAQIITEKTSPKTSNPFLVAVQDSEADYVTTDTLSKVTEAAVSNMPEGLTPDLVQEACESELNEATGTKIAYETKVDLVQTSEAIQESLYPTAQLCPSFEEAEATPSPVLPDIVMEAPLNSLLPSAGASVVQPSVSPLEAPPPVSYDSIKLEPENPPPYEEAMNVALKALGTKEGIKEPESFNAAVQETEAPYISIACDLIKETKLSTEPSPDFSNYSEIAKFEKSVPEHAELVEDSSPESEPVDLFSDDSIPEVPQTQEEAVMLMKESLTEVSETVAQHKEERLSASPQELGKPYLESFQPNLHSTKDAASNDIPTLTKKEKISLQMEEFNTAIYSNDDLLSSKEDKIKESETFSDSSPIEIIDEFPTFVSAKDDSPKLAKEYTDLEVSDKSEIANIQSGADSLPCLELPCDLSFKNIYPKDEVHVSDEFSENRSSVSKASISPSNVSALEPQTEMGSIVKSKSLTKEAEKKLPSDTEKEDRSLSAVLSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKDAMAKIQAKIPGLKRKAD a2ntk1_mouse Pira4 6M7 protein protein mouse Mus musculus Mouse MSCTFTALLCLGLTLSLWIPVLTGSLPKPILRVQPHSVVSRRTKVTFLCEETIGANEYHLYKDGKLYKTVTKNKQKPANKAEFSLSNVDLSNAGQYRCSYNTQDESSGYSDPLELVVTGDYWTPSLSAQASPVVTSGGYVTLQCESWHNNHRFILTVEGPQKLSWMQDSQYNNSTRKYHALFSVGPVTPNQRWIFRCYSYDRNRPYVWSPPSESVELLVSGNLQKPTIKAEPGPVIASKRAMTIWCQGNLDAEVYFLHNEKSQKTQSTQTLQEPGNKGRFFIPSVTQQHAGQYRCYCYSSAGWSQPSDTLELVVTGIYEYYEPRLSVLPSPVVTAGGNMTLHCASDFHYDKFILTKEDKKFTSSLDTEHISSSRQYRALFIIGPTTPTHTGTFRCYGYYKNTPQLWSVPSALQQILISGLSKKPSLLTHQGHILDPGMTLTLQCFSDINYDRYALHKVGGADIMQHSSQQTDTGFSVANFTLGYVRSSTGGQYRCYGAHNLSSEWSASSEPLDILITGQLPLTPSLSVKPNYTVQSGENVSLLCWSMDSVDTFILSKEGSAQQPLRLKSKSHDQQSQAEFSMSAVTSHLSGTYRCYGAQDSSFYLLSSASAPVELTVSETIESSTWSPKRPIPPIPTENKDHTMENLIRMGMAVLVLIVLSILATEAWRSHRQTHPAAGN lirb2_human Leukocyte immunoglobulin-like receptor subfamily B member 2 LILRB2 ILT4 LIR2 MIR10 CD85 antigen-like family member D Immunoglobulin-like transcript 4 Monocyte/macrophage immunoglobulin-like receptor 10 protein protein human Homo sapiens Human MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRLYREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSGPSMGSSPPPTGPISTPAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVVLLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEENLYAAVKDTQPEDGVEMDTRAAASEAPQDVTYAQLHSLTLRRKATEPPPSQEREPPAEPSIYATLAIH ptn11_mouse Tyrosine-protein phosphatase non-receptor type 11 Ptpn11 Protein-tyrosine phosphatase SYP SH-PTP2 protein protein mouse Mus musculus Mouse MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIVDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLVDQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQRSFR app-app-68 3038928 N/A 3038936 unspecified role unspecified role prey prey purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) N/A 3038937 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. N/A 3038936 unspecified role unspecified role prey prey purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) 3038949 3038945 physical association physical association false false false Supp Fig 1B PirB interactspreferentially with oligomeric forms of Amyloid-beta 1-42. lilrb3-app-2 3038928 N/A 3038937 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. N/A 3038938 unspecified role unspecified role bait bait purified purified region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false c_terminus fc-igg tag fc-igg tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false spofr-sf_9 Spodoptera frugiperda insect cells Fall armyworm sf_9 insect cells Derived from pupal ovarian tissue of the fall armyworm Cloned from the parent cell line, IPLB-SF-21-AE (SF-21) derived from immature ovaries of fall armyworm Spodoptera frugiperda pupae cells are susceptible to Baculovirus infection physical association physical association false false false Supp Fig 2 lilrb3-app-3 3038928 N/A 3038936 unspecified role unspecified role bait bait purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) N/A 3038937 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. N/A 3038936 unspecified role unspecified role bait bait purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) 3038962 3038958 physical association physical association false false false Supp Fig 3D app-pira4-1 3038928 N/A 3038936 unspecified role unspecified role bait bait purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) N/A 3038939 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. N/A 3038936 unspecified role unspecified role bait bait purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) 3038970 3038966 physical association physical association false false false Supp Fig 3D-2 weak binding app-lilrb3-2 3038929 N/A 3038937 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. N/A 3038936 unspecified role unspecified role bait bait n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false chemical synthesis Chemical synthesis (Chemical synthesis) physical association physical association false false false Supp Fig 1Ci PirB interactspreferentially with oligomeric forms of Amyloid-beta 1-42. app-lilrb3-3 3038929 N/A 3038936 unspecified role unspecified role bait bait purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) N/A 3038937 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. Stoichiometry: 2.0 N/A 3038936 unspecified role unspecified role bait bait purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) 3038982 3038978 physical association physical association false false false Supp fig 6A PirB interactspreferentially with oligomeric forms of Amyloid-beta 1-42. Amyloid-beta 1-42 oligomers appear to bind preferentially to dimeric PirB, as seen under partially-reducing conditions. app-lilrb3-4 3038929 N/A 3038936 unspecified role unspecified role bait bait purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) N/A 3038937 unspecified role unspecified role prey prey over-expressed over expressed level over-expressed human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. Stoichiometry: 1.0 N/A 3038936 unspecified role unspecified role bait bait purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) 3038990 3038986 physical association physical association false false false Supp Fig 1C, Supp fig 6Ai PirB interacts preferentially with oligomeric forms of Amyloid-beta 1-42. This interaction is seen under fully reducing conditions. lilrb2-app-5 3038930 N/A 3038936 unspecified role unspecified role prey prey purified purified whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) N/A 3038940 unspecified role unspecified role bait bait over-expressed over expressed level over-expressed ecd_D1D2_regions sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false c_terminus fc-igg tag fc-igg tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. N/A 3038936 unspecified role unspecified role prey prey purified purified whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) 3038998 3038993 physical association physical association false false false 2 G/H lilrb2-app-7 3038930 N/A 3038936 unspecified role unspecified role prey prey whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) N/A 3038937 unspecified role unspecified role bait bait ecd_D1D2_regions sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false c_terminus fc-igg tag fc-igg tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. N/A 3038936 unspecified role unspecified role prey prey whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) 3039006 3039001 physical association physical association false false false 2 G/H, Supp 6C app-app-67 3038931 N/A 3038936 unspecified role unspecified role neutral component neutral component purified purified possible_n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) N/A 3038937 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. N/A 3038936 unspecified role unspecified role neutral component neutral component purified purified possible_n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) 3039014 3039010 colocalization colocalization false false false 1 E Oligomerised Amyloid-beta42 peptides were used. app-app-69 3038931 N/A 3038936 unspecified role unspecified role neutral component neutral component purified purified possible_n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) N/A 3038940 unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed c_terminus myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false c_terminus flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. N/A 3038936 unspecified role unspecified role neutral component neutral component purified purified possible_n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) 3039024 3039018 colocalization colocalization false false false Supp 5 Oligomerised Amyloid-beta42 peptides were used. lilrb2-app-6 3038932 N/A 3038936 unspecified role unspecified role neutral component neutral component purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false chemical synthesis Chemical synthesis (Chemical synthesis) N/A 3038936 unspecified role unspecified role neutral component neutral component purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false chemical synthesis Chemical synthesis (Chemical synthesis) direct interaction direct interaction false false false 1A-1 Beta-amyloid peptide consists primarily of high-n oligomers. app-117 3038933 N/A 3038936 unspecified role unspecified role neutral component neutral component purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false chemical synthesis Chemical synthesis (Chemical synthesis) N/A 3038936 unspecified role unspecified role neutral component neutral component purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false chemical synthesis Chemical synthesis (Chemical synthesis) direct interaction direct interaction false false false 1B, S1B Beta-amyloid peptide consists primarily of high-n oligomers. app-lilrb3-1 3038934 N/A 3038936 unspecified role unspecified role neutral component neutral component purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) N/A 3038937 tag visualisation tag visualisation unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. N/A 3038936 unspecified role unspecified role neutral component neutral component purified purified n_terminus biotin tag biotin tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false whole_molecule sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false chemical synthesis Chemical synthesis (Chemical synthesis) 3039043 3039038 colocalization colocalization false false false 3038934 1 C/D Relative to monomeric Amyloid-beta42, oligomerized peptides bound to PirB-expressing cells about 6 times as much. 245tw34at-1 3038935 N/A 3038941 unspecified role unspecified role bait bait physiological level physiological level endogenous level endogenous endogenous endogenous level N/A 3038937 unspecified role unspecified role prey prey under-expressed under expressed level under-expressed physical association physical association false false false 4A