DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ beyhan-2013-1 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Beyhan S., Gutierrez M., Voorhies M., Sil A. DIP original experiment: DIP-254656X PLoS biology 2013 IMEx A temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen. Beyhan S., Gutierrez M., Voorhies M., Sil A. Only protein-protein interactions imex curation beyhan-2013-2 ajeca Ajellomyces capsulatus Darling's disease fungus Histoplasma capsulatum anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Beyhan S., Gutierrez M., Voorhies M., Sil A. DIP original experiment: DIP-254654X PLoS biology 2013 IMEx A temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen. Beyhan S., Gutierrez M., Voorhies M., Sil A. Only protein-protein interactions imex curation beyhan-2013-3 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Beyhan S., Gutierrez M., Voorhies M., Sil A. DIP original experiment: DIP-254659X PLoS biology 2013 IMEx A temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen. Beyhan S., Gutierrez M., Voorhies M., Sil A. Only protein-protein interactions imex curation beyhan-2013-4 ajeca Ajellomyces capsulatus Darling's disease fungus Histoplasma capsulatum anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Beyhan S., Gutierrez M., Voorhies M., Sil A. DIP original experiment: DIP-254655X PLoS biology 2013 IMEx A temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen. Beyhan S., Gutierrez M., Voorhies M., Sil A. Only protein-protein interactions imex curation beyhan-2013-5 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Beyhan S., Gutierrez M., Voorhies M., Sil A. DIP original experiment: DIP-254657X PLoS biology 2013 IMEx A temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen. Beyhan S., Gutierrez M., Voorhies M., Sil A. Only protein-protein interactions imex curation beyhan-2013-6 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Beyhan S., Gutierrez M., Voorhies M., Sil A. DIP original experiment: DIP-254658X PLoS biology 2013 IMEx A temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen. Beyhan S., Gutierrez M., Voorhies M., Sil A. Only protein-protein interactions imex curation velb_ajeca Velvet complex subunit RYP3 RYP3 protein protein ajeca Ajellomyces capsulatus Darling's disease fungus Histoplasma capsulatum MYTLKQDRPHPVPPPPPLTMDHLQHGYSTNTPVTLPGIPEAARSVSTVYEGRIYSLDVVQQPIRARMCGFGDKDRRPLTPPPCIRLIVRDATTQKEIDINEIDTSFYVLTVDLWNAEGTSEVNLVRHSATSPSISTATSSAYPPPANIMPFPQYAQTHGYPQTAYPPYYGGQPGYNPHAGYQYPQGGPDPYYPGLPAASTYYPPGTPTQALGPQSALGPHISSASTGMFTRNLIGSLSASAFRLTDPDDKIGVWFVLQDLSVRTEGSFRLKMNFVNVGTQSQAQDQSPGGTPSSPVINVGSAPVLASAFSEVFQVYSAKKFPGVIESTPLSKCFAFQGIKIPIRKDGVKGPRGGQSHGSKGQDGEGEDWENEG vosa_ajeca Spore development regulator RYP2 RYP2 protein protein ajeca Ajellomyces capsulatus Darling's disease fungus Histoplasma capsulatum MSAPTFAEDPVTQRPALQSADFRLTVRQNPERARVAGGKEKERKAVDPPPIIQLKIDESKDPGQNYLQSPFYFMCCTLYNATEDTPATTAQSTALAGTLVSSLHRLKDTDNMEGGFFVFGDLSVKIEGEFRLKFNLFEMREVKRCGGSRDEVVYIKSILSKPFTVLPPKNFPGMTESTWLSRSFADQGVKLRIRKEARTLLKRPLNRAEPDYPAPPTQPRTPERSGASSQQMVAAYQTNRDYPFYNGPDAKRPRSSVDMSGRGLYEGDARYSYPPHAANPYQGQTYQQGMMQGYPTAGAGVSDYAIRQAQQGSTPTPFGSADESIGSIRSPGAGGYIGQPRYQSYSGAQMPYNLASSTQMSQMGESTPGRTGQAANMGGIVSGQSFSQSAGHMQSPSQVPPAWG a9qxx8_ajeca protein protein ajeca Ajellomyces capsulatus Darling's disease fungus Histoplasma capsulatum MGNGTAAVLEPTFTGYVATTQDALILFEACLTGILHHVPRRPHDRERSQLVKSGSVFIYEENASGIKRWTDGVTWSPSRILGNFLVYRELDKPFPPGEKKRAMKKGNRRPTSTGRPGEPYPRPQESNGTTYSPATSPGAAPYGERNQQSELERQLVGSLVDSYGFKDSGLVKKTMSVTVSGVTHHLVSYYSVEDVMSNRLHTPMQHESLRYIRPRAELTTKQSFRAPIDDFDHATLEDADPTSALYAYRSTLSGAQAYAVPSSGPSYYQLPAYGAPPGYAVGAAGLAGHPASNPYLANTSNSADIPPKQESYPFRSSASYPPGYNPMNPSMQQPLSASTMSSSLNTVLADRSQQQQQPSSAGLYRNPALQPRNVAPDSSSGAVDPSSAYSRGTFGGMDSADQQNVGQHPPYNPATRRESSTLVANVSYYNGDRQPQQQQSQPPSQPQQSHQPPPQQQYFSGPTHSAHASSYQPGPPASMSWNTAATG ryp2-ryp3-1 3256730 N/A 3256736 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3256737 unspecified role unspecified role bait bait N-terminal domain Region 1-208 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false ryp2-a9qxx8_ajeca-1 3256731 N/A 3256738 unspecified role unspecified role prey prey ajeca Ajellomyces capsulatus Darling's disease fungus Histoplasma capsulatum N/A 3256736 unspecified role unspecified role prey prey ajeca Ajellomyces capsulatus Darling's disease fungus Histoplasma capsulatum N/A 3256737 unspecified role unspecified role bait bait ajeca Ajellomyces capsulatus Darling's disease fungus Histoplasma capsulatum association association false false false ryp2-ryp2-1 3256732 N/A 3256737 unspecified role unspecified role prey prey C-terminal domain Region 199-404 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3256737 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false ryp3-a9qxx8_ajeca-1 3256733 N/A 3256738 unspecified role unspecified role prey prey ajeca Ajellomyces capsulatus Darling's disease fungus Histoplasma capsulatum N/A 3256736 unspecified role unspecified role bait bait ajeca Ajellomyces capsulatus Darling's disease fungus Histoplasma capsulatum N/A 3256737 unspecified role unspecified role prey prey ajeca Ajellomyces capsulatus Darling's disease fungus Histoplasma capsulatum association association false false false ryp3-ryp2-1 3256734 N/A 3256736 unspecified role unspecified role bait bait yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3256737 unspecified role unspecified role prey prey N-terminal domain Region 1-208 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false ryp2-ryp2-2 3256735 N/A 3256737 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3256737 unspecified role unspecified role bait bait C-terminal domain Region 199-404 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false