DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ leach-2013-1 ecolx Escherichia coli cd circular dichroism CD CD cd predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251887X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation leach-2013-2 in vitro In vitro nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251883X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation leach-2013-3 in vitro In vitro fluorescence spectr classical fluorescence spectroscopy fluorescence spectr predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251895X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation leach-2013-4 ecolx Escherichia coli pull down pull down predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251891X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation leach-2013-5 in vitro In vitro fluorescence spectr classical fluorescence spectroscopy fluorescence spectr predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251898X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation leach-2013-6 ecolx Escherichia coli nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251888X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation leach-2013-7 ecolx Escherichia coli nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251892X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation leach-2013-8 in vitro In vitro fluorescence spectr classical fluorescence spectroscopy fluorescence spectr predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251896X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation leach-2013-9 in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251884X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation leach-2013-10 in vitro In vitro cd circular dichroism CD CD cd predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251885X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation leach-2013-11 ecolx Escherichia coli pull down pull down predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251889X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation leach-2013-12 ecolx Escherichia coli pull down pull down predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251893X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation leach-2013-13 ecolx Escherichia coli nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251894X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation leach-2013-14 ecolx Escherichia coli nmr nuclear magnetic resonance NMR NMR nmr predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251890X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation leach-2013-15 ecolx Escherichia coli pull down pull down predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251886X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation leach-2013-16 in vitro In vitro fluorescence spectr classical fluorescence spectroscopy fluorescence spectr predetermined predetermined participant predetermined Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. DIP original experiment: DIP-251897X Structure (London, England : 1993) 2013 IMEx Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding. Leach BI., Kuntimaddi A., Schmidt CR., Cierpicki T., Johnson SA., Bushweller JH. Only protein-protein interactions imex curation aff1_human AF4/FMR2 family member 1 AFF1 AF4 FEL MLLT2 PBM1 ALL1-fused gene from chromosome 4 protein Proto-oncogene AF4 Protein FEL protein protein human Homo sapiens Human MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSKSAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKYSRTLNKHFESSSKVAQAPSPCIASTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATISTPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDLVHYTRQGFQQLQELTKTP af9_human Protein AF-9 ALL1-fused gene from chromosome 9 protein Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein YEATS domain-containing protein 3 MLLT3 AF9 YEATS3 protein protein human Homo sapiens Human MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS af9_mouse Protein AF-9 Mllt3 Af9 Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein homolog protein protein mouse Mus musculus Mouse MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPKKVRFDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKDSSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKADSNLLTVTSGQQDKKAPSKRPPASDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSMLPPFDDIVDPNDSDVEENMSSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESDEAEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILEVKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS cbx8_human Chromobox protein homolog 8 Polycomb 3 homolog Rectachrome 1 CBX8 PC3 RC1 protein protein human Homo sapiens Human MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEEREREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSARGIRIPYPGRSPQDLASTSRAREGLRNMGLSPPASSTSTSSTCRAEAPRDRDRDRDRDRERDRERERERERERERERERERGTSRVDDKPSSPGDSSKKRGPKPRKELPDPSQRPLGEPSAGLGEYLKGRKLDDTPSGAGKFPAGHSVIQLARRQDSDLVQCGVTSPSSAEATGKLAVDTFPARVIKHRAAFLEAKGQGALDPNGTRVRHGSGPPSSGGGLYRDMGAQGGRPSLIARIPVARILGDPEEESWSPSLTNLEKVVVTDVTSNFLTVTIKESNTDQGFFKEKR dot1l_human Histone-lysine N-methyltransferase, H3 lysine-79 specific DOT1L KIAA1814 KMT4 Histone H3-K79 methyltransferase DOT1-like protein Lysine N-methyltransferase 4 protein protein human Homo sapiens Human MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSNAATPTKGPEGKVAGPADAPMDSGAEEEKAGAATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMNTANPERKPKKNQTALDALHAQTVSQTAASSPQDAYRSPHSPFYQLPPSVQRHSPNPLLVAPTPPALQKLLESFKIQYLQFLAYTKTPQYKASLQELLGQEKEKNAQLLGAAQQLLSHCQAQKEEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEQDNRALRGQSLQLLKARCEELQLDWATLSLEKLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDALSLHLRGKGALGRELEPDASRLHLELDCTKFSLPHLSSMSPELSMNGQAAGYELCGVLSRPSSKQNTPQYLASPLDQEVVPCTPSHVGRPRLEKLSGLAAPDYTRLSPAKIVLRRHLSQDHTVPGRPAASELHSRAEHTKENGLPYQSPSVPGSMKLSPQDPRPLSPGALQLAGEKSSEKGLRERAYGSSGELITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPSPVLQPRDPSSTLEKQIGANAHGAGSRSLALAPAGFSYAGSVAISGALAGSPASLTPGAEPATLDESSSSGSLFATVGSRSSTPQHPLLLAQPRNSLPASPAHQLSSSPRLGGAAQGPLPEASKGDLPSDSGFSDPESEAKRRIVFTITTGAGSAKQSPSSKHSPLTASARGDCVPSHGQDSRRRGRRKRASAGTPSLSAGVSPKRRALPSVAGLFTQPSGSPLNLNSMVSNINQPLEITAISSPETSLKSSPVPYQDHDQPPVLKKERPLSQTNGAHYSPLTSDEEPGSEDEPSSARIERKIATISLESKSPPKTLENGGGLAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSPLQASSALSQNSLFTFRPALEEPSADAKLAAHPRKGFPGSLSGADGLSPGTNPANGCTFGGGLAADLSLHSFSDGASLPHKGPEAAGLSSPLSFPSQRGKEGSDANPFLSKRQLDGLAGLKGEGSRGKEAGEGGLPLCGPTDKTPLLSGKAAKARDREVDLKNGHNLFISAAAVPPGSLLSGPGLAPAASSAGGAASSAQTHRSFLGPFPPGPQFALGPMSLQANLGSVAGSSVLQSLFSSVPAAAGLVHVSSAATRLTNSHAMGSFSGVAGGTVGGN q6w2j9-1 BCL-6 corepressor BCOR KIAA1575 Long protein protein human Homo sapiens Human MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDASTAHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSEKGREAATSTLGGLGFSSERNPEMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPLNINGASYLRLPWVNPYMEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPLYSPVCTNGERFLYLPPPHYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAADTYSEFHKHYARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKDGSSPPLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGSEIPKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQRSSSCPRMGGTDAVITNVSGSVSSAGRPASASPAPNANADGTKTSRSSVETTPSVIQHVGQPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLPYPAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLPYGLPTGRPEFVTYQDALGLGMVHPMLIPHTPIEITKEEKPERRSRSHERARYEDPTLRNRFSEILETSSTKLHPDVPTDKNLKPNPNWNQGKTVVKSDKLVYVDLLREEPDAKTDTNVSKPSFAAESVGQSAEPPKPSVEPALQQHRDFIALREELGRISDFHETYTFKQPVFTVSKDSVLAGTNKENLGLPVSTPFLEPPLGSDGPAVTFGKTQEDPKPFCVGSAPPSVDVTPTYTKDGADEAESNDGKVLKPKPSKLAKRIANSAGYVGDRFKCVTTELYADSSQLSREQRALQMEGLQEDSILCLPAAYCERAMMRFSELEMKEREGGHPATKDSEMCKFSPADWERLKGNQDKKPKSVTLEEAIAEQNESERCEYSVGNKHRDPFEAPEDKDLPVEKYFVERQPVSEPPADQVASDMPHSPTLRVDRKRKVSGDSSHTETTAEEVPEDPLLKAKRRRVSKDDWPEREMTNSSSNHLEDPHYSELTNLKVCIELTGLHPKKQRHLLHLRERWEQQVSAADGKPGRQSRKEVTQATQPEAIPQGTNITEEKPGRKRAEAKGNRSWSEESLKPSDNEQGLPVFSGSPPMKSLSSTSAGGKKQAQPSCAPASRPPAKQQKIKENQKTDVLCADEEEDCQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLTGEYYVENADGKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCALHEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATYSGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANPPGPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIFRCNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFNPESKELLDLVEFTNEIQTLLGSSVEWLHPSDLASDNYW aff1-mllt3-1 3248663 N/A 3248679 unspecified role unspecified role unspecified role unspecified role Region 743-798 Region 743-798 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3248680 unspecified role unspecified role unspecified role unspecified role Region 500-568 Region 500-568 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false aff1-mllt3-2 3248664 N/A 3248679 unspecified role unspecified role unspecified role unspecified role Region 761-774 Region 761-774 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false in vitro In vitro N/A 3248680 unspecified role unspecified role unspecified role unspecified role Region 490-568 Region 490-568 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false aff1-mllt3-3 3248665 N/A 3248679 unspecified role unspecified role unspecified role unspecified role Region 759-779 Region 759-779 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false FITC-label FITC-label fitc labelled fluorescein isothiocyanate label fluorescein isothiocyanate labbeled FITC labelled FITC labelled fluorescein isothiocyanate labbeled fitc labelled n-term range n-terminal range n-term range n-term range n-terminal range n-term range false pT766 pT766 opthr O-phospho-L-threonine (2S,3R)-2-amino-3-(phosphonooxy)butanoic acid 2-amino-3-hydroxybutanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)butanoic acid MOD_RES Phosphothreonine O-phospho-L-threonine O-phosphorylated L-threonine O3-phosphothreonine threonine phosphate ester OPThr Phospho Phospho Threonyl Phosphorylation phosphorylationt certain certain sequence position certain certain certain sequence position certain false in vitro In vitro N/A 3248681 unspecified role unspecified role unspecified role unspecified role Region 476-569 Region 476-569 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cbx8-mllt3-1 3248666 N/A 3248682 unspecified role unspecified role bait bait Region 315-360 Region 315-360 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3248680 unspecified role unspecified role prey prey Region 500-568 Region 500-568 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli physical association physical association false false false cbx8-mllt3-2 3248667 N/A 3248682 unspecified role unspecified role unspecified role unspecified role Region 330-349 Region 330-349 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false Q9HC52:p.Ala335Val A335V mutation increasing strength mutation increasing interaction strength mutation increasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false FITC-label FITC-label fitc labelled fluorescein isothiocyanate label fluorescein isothiocyanate labbeled FITC labelled FITC labelled fluorescein isothiocyanate labbeled fitc labelled n-term range n-terminal range n-term range n-term range n-terminal range n-term range false in vitro In vitro N/A 3248681 unspecified role unspecified role unspecified role unspecified role Region 476-569 Region 476-569 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false aff1-mllt3-4 3248668 N/A 3248679 unspecified role unspecified role unspecified role unspecified role Region 743-798 Region 743-798 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3248680 unspecified role unspecified role unspecified role unspecified role Region 500-568 Region 500-568 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cbx8-mllt3-3 3248669 N/A 3248682 unspecified role unspecified role unspecified role unspecified role Region 315-360 Region 315-360 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3248680 unspecified role unspecified role unspecified role unspecified role Region 500-568 Region 500-568 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false dot1l-mllt3-1 3248670 N/A 3248683 unspecified role unspecified role unspecified role unspecified role Region 877-900 Region 877-900 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false FITC-label FITC-label fitc labelled fluorescein isothiocyanate label fluorescein isothiocyanate labbeled FITC labelled FITC labelled fluorescein isothiocyanate labbeled fitc labelled n-term range n-terminal range n-term range n-term range n-terminal range n-term range false in vitro In vitro N/A 3248681 unspecified role unspecified role unspecified role unspecified role Region 476-569 Region 476-569 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false aff1-mllt3-5 3248671 N/A 3248679 unspecified role unspecified role unspecified role unspecified role Region 761-774 Region 761-774 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false in vitro In vitro N/A 3248680 unspecified role unspecified role unspecified role unspecified role Region 490-568 Region 490-568 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false aff1-mllt3-6 3248672 N/A 3248679 unspecified role unspecified role unspecified role unspecified role Region 761-774 Region 761-774 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false in vitro In vitro N/A 3248680 unspecified role unspecified role unspecified role unspecified role Region 490-568 Region 490-568 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false dot1l-mllt3-2 3248673 N/A 3248683 unspecified role unspecified role bait bait Region 861-906 Region 861-906 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3248680 unspecified role unspecified role prey prey Region 500-568 Region 500-568 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli physical association physical association false false false bcor-mllt3-1 3248674 N/A 3248684 unspecified role unspecified role bait bait Region 1176-1221 Region 1176-1221 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false ecolx Escherichia coli N/A 3248680 unspecified role unspecified role prey prey Region 500-568 Region 500-568 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli physical association physical association false false false bcor-mllt3-2 3248675 N/A 3248684 unspecified role unspecified role unspecified role unspecified role Region 1176-1221 Region 1176-1221 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3248680 unspecified role unspecified role unspecified role unspecified role Region 500-568 Region 500-568 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false dot1l-mllt3-3 3248676 N/A 3248683 unspecified role unspecified role unspecified role unspecified role Region 861-906 Region 861-906 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3248680 unspecified role unspecified role unspecified role unspecified role Region 500-568 Region 500-568 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false aff1-mllt3-7 3248677 N/A 3248679 unspecified role unspecified role bait bait Region 743-798 Region 743-798 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3248680 unspecified role unspecified role prey prey Region 500-568 Region 500-568 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli physical association physical association false false false bcor-mllt3-3 3248678 N/A 3248684 unspecified role unspecified role unspecified role unspecified role Region 1176-1225 Region 1176-1225 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false FITC-label FITC-label fitc labelled fluorescein isothiocyanate label fluorescein isothiocyanate labbeled FITC labelled FITC labelled fluorescein isothiocyanate labbeled fitc labelled undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false in vitro In vitro N/A 3248681 unspecified role unspecified role unspecified role unspecified role Region 476-569 Region 476-569 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false