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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3247013">
                <names>
                    <shortLabel>davies-2012-2</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="23139410" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-251834X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="wwpdb" dbAc="MI:0805" id="4HQX" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-20732" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="wwpdb" dbAc="MI:0805" id="4HQU" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.1213933109" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="562">
                        <names>
                            <shortLabel>ecolx</shortLabel>
                            <fullName>Escherichia coli</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Davies DR., Gelinas AD., Zhang C., Rohloff JC., Carter JD., O'Connell D., Waugh SM., Wolk SK., Mayfield WS., Burgin AB., Edwards TE., Stewart LJ., Gold L., Janjic N., Jarvis TC.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-251834X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2012</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Davies DR.,  Gelinas AD.,  Zhang C.,  Rohloff JC.,  Carter JD.,  O'Connell D.,  Waugh SM.,  Wolk SK.,  Mayfield WS.,  Burgin AB.,  Edwards TE.,  Stewart LJ.,  Gold L.,  Janjic N.,  Jarvis TC.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3247014">
                <names>
                    <shortLabel>pdgfb_human</shortLabel>
                    <fullName>Platelet-derived growth factor subunit B</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Platelet-derived growth factor B chain</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Platelet-derived growth factor beta polypeptide</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">PDGF-2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Proto-oncogene c-Sis</alias>
                    <alias typeAc="MI:0301" type="gene name">PDGFB</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">PDGF2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">SIS</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P01127" version="SP_107" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_002599.1"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006782" version="SP_242"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1PDG" version="SP_242"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-114608" version="SP_242"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902894" secondary="negative regulation of pri-miRNA transcription by RNA polymerase II" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050921" secondary="positive regulation of chemotaxis" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0062023" secondary="collagen-containing extracellular matrix" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000379" secondary="positive regulation of reactive oxygen species metabolic process" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0018105" secondary="peptidyl-serine phosphorylation" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045840" secondary="positive regulation of mitotic nuclear division" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" secondary="protein homodimerization activity" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045737" secondary="positive regulation of cyclin-dependent protein serine/threonine kinase activity" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035655" secondary="interleukin-18-mediated signaling pathway" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031093" secondary="platelet alpha granule lumen" version="SP_242"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001938" secondary="positive regulation of endothelial cell proliferation" version="SP_242"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048146" secondary="positive regulation of fibroblast proliferation" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_242"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072126" secondary="positive regulation of glomerular mesangial cell proliferation" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" secondary="negative regulation of transcription, DNA-templated" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006468" secondary="protein phosphorylation" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010811" secondary="positive regulation of cell-substrate adhesion" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008083" secondary="growth factor activity" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000573" secondary="positive regulation of DNA biosynthetic process" version="SP_242"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005796" secondary="Golgi lumen" version="SP_242"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060326" secondary="cell chemotaxis" version="SP_242"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_242"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0072255" secondary="metanephric glomerular mesangial cell development" version="SP_242"/>
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                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000330382" version="SP_242" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016323" secondary="basolateral plasma membrane" version="SP_242"/>
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                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MNRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGDPGEEDGAELDLNMTRSHSGGELESLARGRRSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLGA</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-20732-1" id="3247015">
                <names>
                    <shortLabel>pdgfb-7</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-9865E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-20732-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16022178" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>3247013</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3247016">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16022182" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3247014</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="3247017">
                                <names>
                                    <shortLabel>Region 82-190</shortLabel>
                                    <fullName>Region 82-190</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-16022183" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>sufficient to bind</shortLabel>
                                        <fullName>sufficient binding region</fullName>
                                        <alias typeAc="MI:1041" type="synonym">sufficient to bind</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="82"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="190"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="562">
                                <names>
                                    <shortLabel>ecolx</shortLabel>
                                    <fullName>Escherichia coli</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
