<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3242415">
                <names>
                    <shortLabel>macias-2012-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="22796965" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-255471X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15996405" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="https://doi.org/10.1038/nsmb.2344" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21865" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human</shortLabel>
                            <fullName>Homo sapiens</fullName>
                            <alias typeAc="MI:1041" type="synonym">Human</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti tag coip</shortLabel>
                        <fullName>anti tag coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti tag coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0007" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-90" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Macias S., Plass M., Stajuda A., Michlewski G., Eyras E., Cáceres JF.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-255471X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature structural &amp; molecular biology</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2012</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">DGCR8 HITS-CLIP reveals novel functions for the Microprocessor.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Macias S.,  Plass M.,  Stajuda A.,  Michlewski G.,  Eyras E.,  Cáceres JF.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="3242416">
                <names>
                    <shortLabel>macias-2012-2</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="22796965" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-255472X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15996424" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="https://doi.org/10.1038/nsmb.2344" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21865" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human</shortLabel>
                            <fullName>Homo sapiens</fullName>
                            <alias typeAc="MI:1041" type="synonym">Human</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti tag coip</shortLabel>
                        <fullName>anti tag coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti tag coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0007" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-90" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Macias S., Plass M., Stajuda A., Michlewski G., Eyras E., Cáceres JF.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-255472X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Nature structural &amp; molecular biology</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2012</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">DGCR8 HITS-CLIP reveals novel functions for the Microprocessor.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Macias S.,  Plass M.,  Stajuda A.,  Michlewski G.,  Eyras E.,  Cáceres JF.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3242417">
                <names>
                    <shortLabel>rnc_human</shortLabel>
                    <fullName>Ribonuclease 3</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Ribonuclease III</alias>
                    <alias typeAc="MI:0301" type="gene name">DROSHA</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">p241</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">RNASEN</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">RN3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">RNASE3L</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Protein Drosha</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NRR4" version="SP_59" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NW73" version="SP_59" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003723" secondary="RNA binding" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070412" secondary="R-SMAD binding" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_190"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001093882.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_037367.3"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" secondary="metal ion binding" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6V5B" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2NA2" version="SP_190"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-203927" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003725" secondary="double-stranded RNA binding" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006396" secondary="RNA processing" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010586" secondary="miRNA metabolic process" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014069" secondary="postsynaptic density" version="SP_190"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR044442" version="SP_190"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q86YH0" version="SP_59" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042254" secondary="ribosome biogenesis" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2KHX" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_190"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005248351.1"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-528367" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070878" secondary="primary miRNA binding" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050727" secondary="regulation of inflammatory response" version="SP_190"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000344624" version="SP_190" refType="transcript"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-10973107" refType="intact-secondary"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014720" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001530" secondary="lipopolysaccharide binding" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6LXE" version="SP_190"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9Y4Y0" version="SP_59" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030422" secondary="production of siRNA involved in RNA interference" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070877" secondary="microprocessor complex" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_190"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011907" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0017151" secondary="DEAD/H-box RNA helicase binding" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046332" secondary="SMAD binding" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016075" secondary="rRNA catabolic process" version="SP_190"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000999" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6LXD" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045589" secondary="regulation of regulatory T cell differentiation" version="SP_190"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036389" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050829" secondary="defense response to Gram-negative bacterium" version="SP_190"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q7Z5V2" version="SP_59" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9Y2V9" version="SP_59" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005248348.1"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000113360" version="SP_190" refType="gene"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000511367" version="SP_190" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000339845" version="SP_190" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005730" secondary="nucleolus" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6V5C" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004525" secondary="ribonuclease III activity" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050830" secondary="defense response to Gram-positive bacterium" version="SP_190"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-33300N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031053" secondary="primary miRNA processing" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" secondary="protein homodimerization activity" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5B16" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000628" secondary="regulation of miRNA metabolic process" version="SP_190"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000425979" version="SP_190" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031054" secondary="pre-miRNA processing" version="SP_190"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="E7EMP9" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MMQGNTCHRMSFHPGRGCPRGRGGHGARPSAPSFRPQNLRLLHPQQPPVQYQYEPPSAPSTTFSNSPAPNFLPPRPDFVPFPPPMPPSAQGPLPPCPIRPPFPNHQMRHPFPVPPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERHRHRDNRRSPSLERSYKKEYKRSGRSYGLSVVPEPAGCTPELPGEIIKNTDSWAPPLEIVNHRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKEKEPEETMPDKNEEEEEELLKPVWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAKAARPPWEPPKTKLDEDLESSSESECESDEDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPDETEDIKK</sequence>
            </interactor>
            <interactor id="3242418">
                <names>
                    <shortLabel>dgcr8_human</shortLabel>
                    <fullName>Microprocessor complex subunit DGCR8</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">DiGeorge syndrome critical region 8</alias>
                    <alias typeAc="MI:0301" type="gene name">DGCR8</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">DGCRK6</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">C22orf12</alias>
                    <alias typeAc="MI:0306" type="orf name">LP4941</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q8WYQ5" version="SP_57" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-528411" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1X47" version="SP_186"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B2R8G1" version="SP_74" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000263209" version="SP_186" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_186"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2YT4" version="SP_186"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29261N"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5B16" version="SP_186"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6LXD" version="SP_186"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005730" secondary="nucleolus" version="SP_186"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001202" version="SP_186"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6V5C" version="SP_186"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q96G39" version="SP_57" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9H6L8" version="SP_57" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_073557.3"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NRW2" version="SP_57" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001177255.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7CNC" version="SP_186"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016604" secondary="nuclear body" version="SP_186"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070878" secondary="primary miRNA binding" version="SP_186"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6LXE" version="SP_186"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036020" version="SP_186"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3LE4" version="SP_186"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000351989" version="SP_186" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_186"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_186"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0020037" secondary="heme binding" version="SP_186"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8986944" version="SP_186"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6MZE9" version="SP_57" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014720" version="SP_186"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6DCB2" version="SP_57" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000128191" version="SP_186" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" secondary="protein homodimerization activity" version="SP_186"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9H6T7" version="SP_57" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_186"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031053" secondary="primary miRNA processing" version="SP_186"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070877" secondary="microprocessor complex" version="SP_186"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6Y2L0" version="SP_57" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140517" secondary="protein-RNA adaptor activity" version="SP_186"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" secondary="metal ion binding" version="SP_186"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6V5B" version="SP_186"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-203927" version="SP_186"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR040375" version="SP_186"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q96GP8" version="SP_57" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003725" secondary="double-stranded RNA binding" version="SP_186"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_186"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>METDESPSPLPCGPAGEAVMESRARPFQALPREQSPPPPLQTSSGAEVMDVGSGGDGQSELPAEDPFNFYGASLLSKGSFSKGRLLIDPNCSGHSPRTARHAPAVRKFSPDLKLLKDVKISVSFTESCRSKDRKVLYTGAERDVRAECGLLLSPVSGDVHACPFGGSVGDGVGIGGESADKKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDRVDEEALNFPYEDDFDNDVDALLEEGLCAPKKRRTEEKYGGDSDHPSDGETSVQPMMTKIKTVLKSRGRPPTEPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKDNEEREQSSDLTPSGDVSPVKPLSRSAELEFPLDEPDSMGADPGPPDEKDPLGAEAAPGALGQVKAKVEVCKDESVDLEEFRSYLEKRFDFEQVTVKKFRTWAERRQFNREMKRKQAESERPILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECENPSEPFGASVTIDGVTYGSGTASSKKLAKNKAARATLEILIPDFVKQTSEEKPKDSEELEYFNHISIEDSRVYELTSKAGLLSPYQILHECLKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKHTVRGWCKNKRVGKQLASQKILQLLHPHVKNWGSLLRMYGRESSKMVKQETSDKSVIELQQYAKKNKPNLHILSKLQEEMKRLAEEREETRKKPKMSIVASAQPGGEPLCTVDV</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-21865-1" id="3242419">
                <names>
                    <shortLabel>dgcr8-drosha-2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-61848E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15996416" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21865-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3242415</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3242420">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15996423" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3242417</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9606">
                                <names>
                                    <shortLabel>human</shortLabel>
                                    <fullName>Homo sapiens</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Human</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3242421">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15996420" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3242418</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="3242422">
                                <names>
                                    <shortLabel>T7-tag</shortLabel>
                                    <fullName>T7-tag</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-15996421" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>t7 tag</shortLabel>
                                        <fullName>t7 tag</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">MASMTGGQQMG epitope tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">MASMTGGQQMG epitope tag</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0523" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456735" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>n-term range</shortLabel>
                                                <fullName>n-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">n-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1040" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929795" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>n-term range</shortLabel>
                                                <fullName>n-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">n-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1040" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929795" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9606">
                                <names>
                                    <shortLabel>human</shortLabel>
                                    <fullName>Homo sapiens</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Human</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
            <interaction imexId="IM-21865-2" id="3242423">
                <names>
                    <shortLabel>drosha-dgcr8-2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-61848E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-21865-2" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15996435" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>3242416</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3242424">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15996442" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3242418</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9606">
                                <names>
                                    <shortLabel>human</shortLabel>
                                    <fullName>Homo sapiens</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Human</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3242425">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15996439" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3242417</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="3242426">
                                <names>
                                    <shortLabel>Flag-tag</shortLabel>
                                    <fullName>Flag-tag</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-15996440" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>flag tag</shortLabel>
                                        <fullName>flag tag</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">FLAG-tagged</alias>
                                        <alias typeAc="MI:0303" type="go synonym">FLAG</alias>
                                        <alias typeAc="MI:0303" type="go synonym">DYKDDDDKV epitope tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">DYKDDDDKV epitope tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">FLAG</alias>
                                        <alias typeAc="MI:1041" type="synonym">FLAG-tagged</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0518" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456503" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>n-term range</shortLabel>
                                                <fullName>n-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">n-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1040" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929795" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>n-term range</shortLabel>
                                                <fullName>n-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">n-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1040" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929795" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="9606">
                                <names>
                                    <shortLabel>human</shortLabel>
                                    <fullName>Homo sapiens</fullName>
                                    <alias typeAc="MI:1041" type="synonym">Human</alias>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
