DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ daugaard-2012-1 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Daugaard M., Baude A., Fugger K., Povlsen LK., Beck H., Sørensen CS., Petersen NH., Sorensen PH., Lukas C., Bartek J., Lukas J., Rohde M., Jäättelä M. DIP original experiment: DIP-255464X Nature structural & molecular biology 2012 IMEx LEDGF (p75) promotes DNA-end resection and homologous recombination. Daugaard M., Baude A., Fugger K., Povlsen LK., Beck H., Sørensen CS., Petersen NH., Sorensen PH., Lukas C., Bartek J., Lukas J., Rohde M., Jäättelä M. Only protein-protein interactions imex curation daugaard-2012-2 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Daugaard M., Baude A., Fugger K., Povlsen LK., Beck H., Sørensen CS., Petersen NH., Sorensen PH., Lukas C., Bartek J., Lukas J., Rohde M., Jäättelä M. DIP original experiment: DIP-255467X Nature structural & molecular biology 2012 IMEx LEDGF (p75) promotes DNA-end resection and homologous recombination. Daugaard M., Baude A., Fugger K., Povlsen LK., Beck H., Sørensen CS., Petersen NH., Sorensen PH., Lukas C., Bartek J., Lukas J., Rohde M., Jäättelä M. Only protein-protein interactions imex curation daugaard-2012-3 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Daugaard M., Baude A., Fugger K., Povlsen LK., Beck H., Sørensen CS., Petersen NH., Sorensen PH., Lukas C., Bartek J., Lukas J., Rohde M., Jäättelä M. DIP original experiment: DIP-255469X Nature structural & molecular biology 2012 IMEx LEDGF (p75) promotes DNA-end resection and homologous recombination. Daugaard M., Baude A., Fugger K., Povlsen LK., Beck H., Sørensen CS., Petersen NH., Sorensen PH., Lukas C., Bartek J., Lukas J., Rohde M., Jäättelä M. Only protein-protein interactions imex curation daugaard-2012-4 in vitro In vitro anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Daugaard M., Baude A., Fugger K., Povlsen LK., Beck H., Sørensen CS., Petersen NH., Sorensen PH., Lukas C., Bartek J., Lukas J., Rohde M., Jäättelä M. DIP original experiment: DIP-255465X Nature structural & molecular biology 2012 IMEx LEDGF (p75) promotes DNA-end resection and homologous recombination. Daugaard M., Baude A., Fugger K., Povlsen LK., Beck H., Sørensen CS., Petersen NH., Sorensen PH., Lukas C., Bartek J., Lukas J., Rohde M., Jäättelä M. Only protein-protein interactions imex curation daugaard-2012-5 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Daugaard M., Baude A., Fugger K., Povlsen LK., Beck H., Sørensen CS., Petersen NH., Sorensen PH., Lukas C., Bartek J., Lukas J., Rohde M., Jäättelä M. DIP original experiment: DIP-255468X Nature structural & molecular biology 2012 IMEx LEDGF (p75) promotes DNA-end resection and homologous recombination. Daugaard M., Baude A., Fugger K., Povlsen LK., Beck H., Sørensen CS., Petersen NH., Sorensen PH., Lukas C., Bartek J., Lukas J., Rohde M., Jäättelä M. Only protein-protein interactions imex curation daugaard-2012-6 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Daugaard M., Baude A., Fugger K., Povlsen LK., Beck H., Sørensen CS., Petersen NH., Sorensen PH., Lukas C., Bartek J., Lukas J., Rohde M., Jäättelä M. DIP original experiment: DIP-255466X Nature structural & molecular biology 2012 IMEx LEDGF (p75) promotes DNA-end resection and homologous recombination. Daugaard M., Baude A., Fugger K., Povlsen LK., Beck H., Sørensen CS., Petersen NH., Sorensen PH., Lukas C., Bartek J., Lukas J., Rohde M., Jäättelä M. Only protein-protein interactions imex curation daugaard-2012-7 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Daugaard M., Baude A., Fugger K., Povlsen LK., Beck H., Sørensen CS., Petersen NH., Sorensen PH., Lukas C., Bartek J., Lukas J., Rohde M., Jäättelä M. DIP original experiment: DIP-255470X Nature structural & molecular biology 2012 IMEx LEDGF (p75) promotes DNA-end resection and homologous recombination. Daugaard M., Baude A., Fugger K., Povlsen LK., Beck H., Sørensen CS., Petersen NH., Sorensen PH., Lukas C., Bartek J., Lukas J., Rohde M., Jäättelä M. Only protein-protein interactions imex curation ctip_human DNA endonuclease RBBP8 RBBP8 CTIP CtBP-interacting protein Retinoblastoma-binding protein 8 Retinoblastoma-interacting protein and myosin-like Sporulation in the absence of SPO11 protein 2 homolog protein protein human Homo sapiens Human MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHGTSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTRNTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQNRTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFSMNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASDGNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVLDDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPGADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPYFKGDERETSLQNFPHIEVVRKKEERRKLLGHTCKECEIYYADMPAEEREKKLASCSRHRFRYIPPNTPENFWEVGFPSTQTCMERGYIKEDLDPCPRPKRRQPYNAIFSPKGKEQKT psip1_human PC4 and SFRS1-interacting protein PSIP1 DFS70 LEDGF PSIP2 Lens epithelium-derived growth factor Transcriptional coactivator p75/p52 Dense fine speckles 70 kDa protein CLL-associated antigen KW-7 protein protein human Homo sapiens Human MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEKEQTGSKTLNGGSDAQDGNQPQHNGESNEDSKDNHEASTKKKPSSEERETEISLKDSTLDN h3k9-2 Histone H3 N-terminal Peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) ARTKQTARKSTGGKAPRKQLA h2ax_human Histone H2AX H2AX H2AFX Histone H2A.X protein protein human Homo sapiens Human MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTSATVGPKAPSGGKKATQASQEY rb_human Retinoblastoma-associated protein pRb pp110 p105-Rb RB1 p110-RB1 protein protein human Homo sapiens Human MPPKTPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTALCQKLKIPDHVRERAWLTWEKVSSVDGVLGGYIQKKKELWGICIFIAAVDLDEMSFTFTELQKNIEISVHKFFNLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCELIYLTQPSSSISTEINSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCVLDYFIKLSPPMLLKEPYKTAVIPINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFKNFIPFMNSLGLVTSNGLPEVENLSKRYEEIYLKNKDLDARLFLDHDKTLQTDSIDSFETQRTPRKSNLDEEVNVIPPHTPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDIGYIFKEKFAKAVGQGCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHMSLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKAEGNLTREMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLPLQNNHTAADMYLSPVRSPKKKGSTTRVNSTANAETQATSAFQTQKPLKSTSLSLFYKKVYRLAYLRLNTLCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYGICKVKNIDLKFKIIVTAYKDLPHAVQETFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPHIPRSPYKFPSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEKFQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQKLAEMTSTRTRMQKQKMNDSMDTSNKEEK h3k27me Histone 3 fragment [ATKAARKSAPATGGVKKPHRYRPG] peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) ATKAARKSAPATGGVKKPHRYRPG psip1-rbbp8-1 3242308 N/A 3242315 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3242316 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false psip1-rbbp8-2 3242309 N/A 3242315 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3242316 unspecified role unspecified role bait bait GFP-tag GFP-tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false h3k4-psip1-1 3242310 N/A 3242317 unspecified role unspecified role bait bait K4me1 K4me1 n6me1lys N6-methyl-L-lysine (2S)-2-amino-6-methylaminohexanoic acid MOD_RES N6-methyllysine N(zeta)-methyllysine N6-methyl-L-lysine N6-methylated L-lysine epsilon-methyllysine Methyl Methylation N-methyl Lysyl N6Me1Lys certain certain sequence position certain certain certain sequence position certain false Biotin-tag Biotin-tag biotin tag biotin tag c-terminal c-terminal position c-term carboxy-terminus c-terminus c-term c-terminus carboxy-terminus c-terminal c-terminal c-terminal position c-term carboxy-terminus c-terminus c-term c-terminus carboxy-terminus c-terminal false in vitro In vitro N/A 3242316 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false psip1-rbbp8-3 3242311 N/A 3242315 unspecified role unspecified role prey prey in vitro In vitro N/A 3242316 unspecified role unspecified role bait bait ecolx Escherichia coli direct interaction direct interaction false false false rbbp8-h2afx-1 3242312 N/A 3242318 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3242319 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3242315 unspecified role unspecified role bait bait GFP-tag GFP-tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human association association false false false rbbp8-psip1-1 3242313 N/A 3242316 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3242315 unspecified role unspecified role bait bait GFP-tag GFP-tag gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false h3k36-psip1-1 3242314 N/A 3242320 unspecified role unspecified role bait bait K36me1 K36me1 n6me1lys N6-methyl-L-lysine (2S)-2-amino-6-methylaminohexanoic acid MOD_RES N6-methyllysine N(zeta)-methyllysine N6-methyl-L-lysine N6-methylated L-lysine epsilon-methyllysine Methyl Methylation N-methyl Lysyl N6Me1Lys certain certain sequence position certain certain certain sequence position certain false K36me2 K36me2 n6me2lys N6,N6-dimethyl-L-lysine (2S)-2-amino-6-(dimethylamino)hexanoic acid MOD_RES N6,N6-dimethyllysine N(zeta)-dimethyllysine N6,N6-dimethyl-L-lysine N6,N6-dimethylated L-lysine epsilon-dimethyllysine lysine derivative Lys(y) Dimethyl N6Me2Lys di-Methylation dimethylk certain certain sequence position certain certain certain sequence position certain false K36me3 K36me3 n6me3+lys N6,N6,N6-trimethyl-L-lysine (5S)-5-amino-5-carboxy-N,N,N-trimethylpentan-1-aminium 2-amino-6-(trimethylammonio)hexanoic acid 5-azanyl-5-carboxy-N,N,N-trimethylpentanazanium MOD_RES N6,N6,N6-trimethyllysine N(zeta)-trimethyllysine N6,N6,N6-trimethyl-L-lysine N6,N6,N6-trimethylated L-lysine N6,N6,N6-trimethyllysin-N6-ium N6,N6,N6-trimethyllysine cation epsilon-trimethyllysine N-trimethylation (of lysine) N6Me3+Lys Trimethyl tri-Methylation certain certain sequence position certain certain certain sequence position certain false Biotin-tag Biotin-tag biotin tag biotin tag c-terminal c-terminal position c-term carboxy-terminus c-terminus c-term c-terminus carboxy-terminus c-terminal c-terminal c-terminal position c-term carboxy-terminus c-terminus c-term c-terminus carboxy-terminus c-terminal false in vitro In vitro N/A 3242316 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false