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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3233540">
                <names>
                    <shortLabel>giardina-2011-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="22143761" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="wwpdb" dbAc="MI:0805" id="3RCH" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15956628" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="wwpdb" dbAc="MI:0805" id="3RBF" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.1111456108" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-17792" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-249736X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="wwpdb" dbAc="MI:0805" id="3RBL" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="562">
                        <names>
                            <shortLabel>ecolx</shortLabel>
                            <fullName>Escherichia coli</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1272" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Giardina G., Montioli R., Gianni S., Cellini B., Paiardini A., Voltattorni CB., Cutruzzolà F.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-249736X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2011</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Giardina G.,  Montioli R.,  Gianni S.,  Cellini B.,  Paiardini A.,  Voltattorni CB.,  Cutruzzolà F.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3233541">
                <names>
                    <shortLabel>ddc_human</shortLabel>
                    <fullName>Aromatic-L-amino-acid decarboxylase</fullName>
                    <alias typeAc="MI:0301" type="gene name">DDC</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">AADC</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">DOPA decarboxylase</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P20711" version="SP_86" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019904" secondary="protein domain specific binding" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033076" secondary="isoquinoline alkaloid metabolic process" version="SP_205"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000781.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_205"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5W5T9" version="SP_141" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3RBF" version="SP_205"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000357936" version="SP_205" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030170" secondary="pyridoxal phosphate binding" version="SP_205"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001229818.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015842" secondary="aminergic neurotransmitter loading into synaptic vesicle" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0036467" secondary="5-hydroxy-L-tryptophan decarboxylase activity" version="SP_205"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001229817.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001076440.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002129" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006520" secondary="cellular amino acid metabolic process" version="SP_205"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000350616" version="SP_205" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR010977" version="SP_205"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="E7EU95" version="SP_141" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q75MJ6" version="SP_99" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030424" secondary="axon" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0052314" secondary="phytoalexin metabolic process" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035690" secondary="cellular response to drug" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015421" version="SP_205"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-209905" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043025" secondary="neuronal cell body" version="SP_205"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q16723" version="SP_86" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015422" version="SP_205"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="E7ER62" version="SP_141" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071363" secondary="cellular response to growth factor stimulus" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016831" secondary="carboxy-lyase activity" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016597" secondary="amino acid binding" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0036468" secondary="L-dopa decarboxylase activity" version="SP_205"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001229816.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042427" secondary="serotonin biosynthetic process" version="SP_205"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000132437" version="SP_205" refType="gene"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1632155" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004058" secondary="aromatic-L-amino-acid decarboxylase activity" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042416" secondary="dopamine biosynthetic process" version="SP_205"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000403644" version="SP_205" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046684" secondary="response to pyrethroid" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071312" secondary="cellular response to alkaloid" version="SP_205"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3RCH" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007623" secondary="circadian rhythm" version="SP_205"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3RBL" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" secondary="extracellular exosome" version="SP_205"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="C9IYA0" version="SP_141" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006584" secondary="catecholamine metabolic process" version="SP_205"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001229815.1"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010259" secondary="multicellular organism aging" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR021115" version="SP_205"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MNASEFRRRGKEMVDYMANYMEGIEGRQVYPDVEPGYLRPLIPAAAPQEPDTFEDIINDVEKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMDWLGKMLELPKAFLNEKAGEGGGVIQGSASEATLVALLAARTKVIHRLQAASPELTQAAIMEKLVAYSSDQAHSSVERAGLIGGVKLKAIPSDGNFAMRASALQEALERDKAAGLIPFFMVATLGTTTCCSFDNLLEVGPICNKEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFNPHKWLLVNFDCSAMWVKKRTDLTGAFRLDPTYLKHSHQDSGLITDYRHWQIPLGRRFRSLKMWFVFRMYGVKGLQAYIRKHVQLSHEFESLVRQDPRFEICVEVILGLVCFRLKGSNKVNEALLQRINSAKKIHLVPCHLRDKFVLRFAICSRTVESAHVQRAWEHIKELAADVLRAERE</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-17792-1" id="3233542">
                <names>
                    <shortLabel>ddc-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-189183E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15956642" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-17792-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3233540</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3233543">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15956646" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3233541</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="562">
                                <names>
                                    <shortLabel>ecolx</shortLabel>
                                    <fullName>Escherichia coli</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
