DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ ikeda-2011-1 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219122X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-2 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219130X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-3 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219139X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-4 in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219147X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-5 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219123X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-6 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219131X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-7 in vitro In vitro comigration in sds comigration in sds page comigration in sds western blot western blot Immuno blot Immuno blot Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219137X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-8 in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219138X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-9 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219124X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-10 in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219146X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-11 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219149X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-12 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219141X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-13 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219125X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-14 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219154X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-15 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219140X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-16 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219132X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-17 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219148X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-18 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219126X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-19 in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219151X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-20 in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219143X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-21 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219133X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-22 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip de novo protein sequence de novo protein sequencing by mass spectrometry de novo protein sequence Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219142X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-23 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219127X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-24 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219150X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-25 in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219134X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-26 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219128X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-27 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219145X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-28 in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219153X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-29 in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219135X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-30 in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219152X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-31 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219144X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-32 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219129X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation ikeda-2011-33 in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. DIP original experiment: DIP-219136X Nature 2011 IMEx SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Ikeda F., Deribe YL., Skånland SS., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk SJ., Goswami P., Nagy V., Terzic J., Tokunaga F., Androulidaki A., Nakagawa T., Pasparakis M., Iwai K., Sundberg JP., Schaefer L., Rittinger K., Macek B., Dikic I. Only protein-protein interactions imex curation hoil1_mouse RanBP-type and C3HC4-type zinc finger-containing protein 1 Rbck1 Rbck Ubce7ip3 Uip28 Heme-oxidized IRP2 ubiquitin ligase 1 homolog UbcM4-interacting protein 28 Ubiquitin-conjugating enzyme 7-interacting protein 3 RING-type E3 ubiquitin transferase HOIL-1 protein protein mouse Mus musculus Mouse MDEKTKKAEEMALSLARAVAGGDEQAAIKYATWLAEQRVPLRVQVKPEVSPTQDIRLCVSVEDAYMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPSLQQWVVGQRLARDQETLHSHGIRRNGDGAYLYLLSARNTSLNPQELQRQRQLRMLEDLGFKDLTLQSRGPLEPVLPKPRTNQEPGQPDAAPESPPVGWQCPGCTFINKPTRPGCEMCCRARPETYQIPASYQPDEEERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLEQRSLVLNTEPTECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVACPFIDSTYSCPGKLLEREIRALLSPEDYQRFLDLGVSIAENRSTLSYHCKTPDCRGWCFFEDDVNEFTCPVCTRVNCLLCKAIHEHMNCREYQDDLALRAQNDVAARQTTEMLKVMLQQGEAMHCPQCRIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNCH shrpn_mouse Sharpin Shank-associated RH domain-interacting protein Shank-interacting protein-like 1 Sharpin Sipl1 Cpdm protein protein mouse Mus musculus Mouse MSPPAGGAAVAADPASPVVLLAVHAAVRPLGAGQDAEAQPRKLQLIADPERPGRFRLGLLGTEPGAVSLEWPLEAICYTVRGPNQHELQPPPGGPGTFSVHFLDPEEAQQWAALVRDATAEGQNGSGSPAPAPAPAMCPISPPCSSMAQIPKATQPEVDLPQSSGNFKKEELATRLSQAIAGGDEKAAAQVAAVLAQHHVALNVQLMEAWFPPGPIRLQVTVEDATSVLSSSSSAHVSLKIHPHCSIAALQDQVFSEFGFPPAVQRWVIGRCLCMPERSLASYGVSQDGDPAFLYLLSAPREVSGQSLQNSKMDRKLGLFPQSLGLPHDLQPSSSSLPSPSQPGWSCPSCTFINASNRPGCEMCSTQRPCAWDPLAAAST rnf31_mouse E3 ubiquitin-protein ligase RNF31 HOIL-1-interacting protein Rnf31 Paul Putative Ariadne-like ubiquitin ligase RING finger protein 31 RING-type E3 ubiquitin transferase RNF31 protein protein mouse Mus musculus Mouse MPGDEERGFLAAREELASALRWDSAQVFPLEQLMPLLATSLPPAARYLQLDAGRLVRCNAHGEPRNYLNTLSTALNILEKYGRNLLSPQRPRYWRSVKFNNPVFRSTVDAVQGGRDVLRLYGYTEERPDGLSFPEGQEEPDEYQVAVVTLEVLLLRTELSLLLQNTHPRQNALDQLLRESVEDGMLQLSEFHPLLREIVPGPRPSAQGSTPGPCFLCGSAPGTLHCPACNQVSCPACDILFHGHPSRAHHLRQALPGSHQTASLSSSLPASSQPRPPSSSLALGDSSLSSPDPANACLPWHCLTCATLNEPWAVFCAVCSQPKGCKVPGIEGSHGTGGLEPEPARDQWACQSCTFENEAAAVLCAICERPRLAQPPSLVVDSHDAGVCQQSLKQEDPLLTAAQPQVWYCDHCTFCNSGPVWVCAMCNRTRDPIPTQPALQSYPSSLEKGRPKPGSSQHLGSSLPASCGDPEKQRQDKMRKEGLQLVSMIQEGETAGASPEEVFSALQYSGTEVPLQWLRSELSYVLEMVAELAGQQDPELGAFSCQEARKAWLDRHGNLDEAVEECVRARRRKVHELQSLGFGPKEGSLQALFQHGGDVARALTELQRQRLEPFHQRLWDRDPEPTPCWDGLDRQSLVRRLLAVYTLPSWGRAELALALLQETPRNYELLDVVEAVRHSQDRAFLRRLLAQECAVCGWALPRNRMQALISCECTICPECFRQHFTIALKEKHITDMVCPACGRPDLTDDAQLLSYFSTLDIQLRESLDPDAYALFHKKLTEAVLMRDPKFLWCAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRTNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPDPNCKVKKSLHGHHPRDCLFYLRDWTAARLQKLLQDNNVMFNTEPPAGTRAVPGGGCRVMEQKEVHSGFRDEACGKETPPGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATIRYLHLAPQPADGEDLPAYQARLLQKLREEVPLGQSIARRRK hoil1_human RanBP-type and C3HC4-type zinc finger-containing protein 1 RBCK1 C20orf18 RNF54 UBCE7IP3 XAP3 XAP4 Ubiquitin-conjugating enzyme 7-interacting protein 3 Hepatitis B virus X-associated protein 4 HBV-associated factor 4 RING finger protein 54 Heme-oxidized IRP2 ubiquitin ligase 1 RING-type E3 ubiquitin transferase HOIL-1 protein protein human Homo sapiens Human MDEKTKKAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSVQLKPEVSPTQDIRLWVSVEDAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWVIGQRLARDQETLHSHGVRQNGDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCRARPEAYQVPASYQPDEEERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQNCH shrpn_human Sharpin SHARPIN SIPL1 Shank-associated RH domain-interacting protein Shank-interacting protein-like 1 PSEC0216 protein protein human Homo sapiens Human MAPPAGGAAAAASDLGSAAVLLAVHAAVRPLGAGPDAEAQLRRLQLSADPERPGRFRLELLGAGPGAVNLEWPLESVSYTIRGPTQHELQPPPGGPGTLSLHFLNPQEAQRWAVLVRGATVEGQNGSKSNSPPALGPEACPVSLPSPPEASTLKGPPPEADLPRSPGNLTEREELAGSLARAIAGGDEKGAAQVAAVLAQHRVALSVQLQEACFPPGPIRLQVTLEDAASAASAASSAHVALQVHPHCTVAALQEQVFSELGFPPAVQRWVIGRCLCVPERSLASYGVRQDGDPAFLYLLSAPREAPATGPSPQHPQKMDGELGRLFPPSLGLPPGPQPAASSLPSPLQPSWSCPSCTFINAPDRPGCEMCSTQRPCTWDPLAAAST nemo_mouse NF-kappa-B essential modulator NF-kappa-B essential modifier Inhibitor of nuclear factor kappa-B kinase subunit gamma IkB kinase-associated protein 1 Ikbkg Nemo protein protein mouse Mus musculus Mouse MNKHPWKNQLSEMVQPSGGPAEDQDMLGEESSLGKPAMLHLPSEQGTPETLQRCLEENQELRDAIRQSNQMLRERCEELLHFQVSQREEKEFLMCKFQEARKLVERLSLEKLDLRSQREQALKELEQLKKCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKDRQALEGRIRAVSEQVRQLESEREVLQQQHSVQVDQLRMQNQSVEAALRMERQAASEEKRKLAQLQAAYHQLFQDYDSHIKSSKGMQLEDLRQQLQQAEEALVAKQELIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERHAREKLVEKKEYLQEQLEQLQREFNKLKVGCHESARIEDMRKRHVETPQPPLLPAPAHHSFHLALSNQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE ubiq_human UBIQ_HUMAN protein protein human Homo sapiens Human MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG rnf31_human E3 ubiquitin-protein ligase RNF31 Zinc in-between-RING-finger ubiquitin-associated domain protein RNF31 ZIBRA HOIL-1-interacting protein RING finger protein 31 RING-type E3 ubiquitin transferase RNF31 protein protein human Homo sapiens Human MPGEEEERAFLVAREELASALRRDSGQAFSLEQLRPLLASSLPLAARYLQLDAARLVRCNAHGEPRNYLNTLSTALNILEKYGRNLLSPQRPRYWRGVKFNNPVFRSTVDAVQGGRDVLRLYGYTEEQPDGLSFPEGQEEPDEHQVATVTLEVLLLRTELSLLLQNTHPRQQALEQLLEDKVEDDMLQLSEFDPLLREIAPGPLTTPSVPGSTPGPCFLCGSAPGTLHCPSCKQALCPACDHLFHGHPSRAHHLRQTLPGVLQGTHLSPSLPASAQPRPQSTSLLALGDSSLSSPNPASAHLPWHCAACAMLNEPWAVLCVACDRPRGCKGLGLGTEGPQGTGGLEPDLARGRWACQSCTFENEAAAVLCSICERPRLAQPPSLVVDSRDAGICLQPLQQGDALLASAQSQVWYCIHCTFCNSSPGWVCVMCNRTSSPIPAQHAPRPYASSLEKGPPKPGPPRRLSAPLPSSCGDPEKQRQDKMREEGLQLVSMIREGEAAGACPEEIFSALQYSGTEVPLQWLRSELPYVLEMVAELAGQQDPGLGAFSCQEARRAWLDRHGNLDEAVEECVRTRRRKVQELQSLGFGPEEGSLQALFQHGGDVSRALTELQRQRLEPFRQRLWDSGPEPTPSWDGPDKQSLVRRLLAVYALPSWGRAELALSLLQETPRNYELGDVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCAQCSFGFIYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRVIEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLINAHSLDPATLYEVEELETATERYLHVRPQPLAGEDPPAYQARLLQKLTEEVPLGQSIPRRRK tnip1_mouse TNFAIP3-interacting protein 1 Tnip1 Abin Naf1 Nef-associated factor 1 Virion-associated nuclear shuttling protein A20-binding inhibitor of NF-kappa-B activation 1 protein protein mouse Mus musculus Mouse MEGRGPYRIYDPGGSTPLGEVSAAFERLVEENTRLKGKMQGIKMLGELLEESQMEASRLRQKAEELVKDSELSPPTSAPSLVSFDDLAELTGQDTKVQVHPATSTAATTTATATTGNSMEKPEPASKSPSNGASSDFEVVPTEEQNSPETGSHPTNMMDLGPPPPEDSNLKLHLQRLETTLSVCAEEPDHSQLFTHLGRMALEFNRLASKVHKNEQRTSILQTLCEQLRQENEALKAKLDKGLEQRDLAAERLREENTELKKLLMNSSCKEGLCGQPSSPKPEGAGKKGVAGQQQASVMASKVPEAGAFGAAEKKVKLLEQQRMELLEVNKQWDQHFRSMKQQYEQKITELRQKLVDLQKQVTELEAEREQKQRDFDRKLLLAKSKIEMEETDKEQLTAEAKELRQKVRYLQDQLSPLTRQREYQEKEIQRLNKALEEALSIQASPSSPPAAFGSPEGVGGHLRKQELVTQNELLKQQVKIFEEDFQRERSDRERMNEEKEELKKQVEKLQAQVTLTNAQLKTLKEEEKAKEALKQQKRKAKASGERYHMEPHPEHVCGAYPYAYPPMPAMVPHHAYKDWSQIRYPPPPVPMEHPPPHPNSRLFHLPEYTWRPPCAGIRNQSSQVMDPPPDRPAEPESADNDCDGPQ ikka_mouse Inhibitor of nuclear factor kappa-B kinase subunit alpha I-kappa-B kinase 1 Conserved helix-loop-helix ubiquitous kinase Nuclear factor NF-kappa-B inhibitor kinase alpha Chuk Ikka protein protein mouse Mus musculus Mouse MERPPGLRPGAGGPWEMRERLGTGGFGNVSLYQHRELDLKIAIKSCRLELSSKNRERWCHEIQIMKKLDHANVVKACDVPEELNFLINDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKTIHKIIDLGYAKDVDQGSLCTSFVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPKCIFACEEMTGEVRFSSHLPQPNSLCSLIVEPMESWLQLMLNWDPQQRGGPIDLTLKQPRCFALMDHILNLKIVHILNMTSAKIISFLLPCDESLHSLQSRIERETGINTGSQELLSETGISLDPRKPASQCVLDGVRGCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPIIQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKLEFFRKSIQLDLERYSEQMTYGISSEKMLKAWKEMEEKAIHYSEVGVIGYLEDQIMSLHTEIMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPPDHLYSDSTEMVKIIVHTVQSQDRVLKELFGHLSKLLGCKQKIIDLLPKVEVALSNIKEADNTVMFMQGKRQKEIWHLLKIACTQSSARSLVGSSLEGTVTPPVSAWLPPTLADREHPLTCVVTPQDGETLAQMIEENLNCLGHLSTIIREANEDQSSSLMSLDWSWLAE nemo_human NF-kappa-B essential modulator IKBKG FIP3 NEMO NF-kappa-B essential modifier Inhibitor of nuclear factor kappa-B kinase subunit gamma IkB kinase-associated protein 1 FIP-3 protein protein human Homo sapiens Human MNRHLWKSQLCEMVQPSGGPAADQDVLGEESPLGKPAMLHLPSEQGAPETLQRCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARKLVERLGLEKLDLKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQALEGRARAASEQARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLKASCQESARIEDMRKRHVEVSQAPLPPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE rnf31-rbck1-13 3224268 N/A 3224301 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3224302 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3224303 unspecified role unspecified role bait bait mouse Mus musculus Mouse association association false false false sharpin-rbck1-9 3224269 N/A 3224304 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3224305 unspecified role unspecified role bait bait GFP-tag GFP-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false sharpin-ikbkg-2 3224270 N/A 3224306 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3224302 unspecified role unspecified role bait bait mouse Mus musculus Mouse N/A 3224303 unspecified role unspecified role prey prey mouse Mus musculus Mouse association association false false false ub-sharpin-1 3224271 N/A 3224305 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3224307 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal false ecolx Escherichia coli direct interaction direct interaction false false false rnf31-rbck1-14 3224272 N/A 3224301 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3224303 unspecified role unspecified role bait bait mouse Mus musculus Mouse physical association physical association false false false rbck1-rnf31-29 3224273 N/A 3224304 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3224305 unspecified role unspecified role prey prey GFP-tag GFP-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3224308 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human association association false false false ub-9 3224274 N/A 3224307 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction false false false tnip1-ub-2 3224275 N/A 3224307 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3224309 unspecified role unspecified role bait bait UBAN domain Region 465-520 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false Q9WUU8:p.Asp485Ala D485A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli physical association physical association false false false rnf31-sharpin-5 3224276 N/A 3224302 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3224303 unspecified role unspecified role bait bait mouse Mus musculus Mouse physical association physical association false false false ub-rbck1-1 3224277 N/A 3224304 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3224307 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal false ecolx Escherichia coli direct interaction direct interaction false false false rnf31-ub-1 3224278 N/A 3224308 unspecified role unspecified role bait bait NZF1 domain Region 350-379 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3224307 unspecified role unspecified role prey prey ecolx Escherichia coli direct interaction direct interaction false false false ikbkg-chuk-12 3224279 N/A 3224310 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3224306 unspecified role unspecified role bait bait mouse Mus musculus Mouse physical association physical association false false false rnf31-rbck1-15 3224280 N/A 3224304 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3224305 unspecified role unspecified role prey prey GFP-tag GFP-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3224308 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human association association false false false sharpin-ub-1 3224281 N/A 3224305 unspecified role unspecified role bait bait region Δ350-374 required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false NZF domain Region 340-387 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false Q9H0F6:p.[Thr358Leu;Phe359Val] T358L/F359V mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3224307 unspecified role unspecified role prey prey ecolx Escherichia coli direct interaction direct interaction false false false sharpin-rnf31-5 3224282 N/A 3224302 unspecified role unspecified role bait bait mouse Mus musculus Mouse N/A 3224303 unspecified role unspecified role prey prey mouse Mus musculus Mouse physical association physical association false false false rbck1-sharpin-1 3224283 N/A 3224304 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3224305 unspecified role unspecified role prey prey GFP-tag GFP-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false rnf31-sharpin-6 3224284 N/A 3224308 unspecified role unspecified role bait bait NZF2 domain Region 408-438 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3224305 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false UBL domain Region 233-314 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false rnf31-rbck1-16 3224285 N/A 3224304 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3224308 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false ub-rnf31-1 3224286 N/A 3224308 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3224307 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal false ecolx Escherichia coli physical association physical association false false false tnip1-ub-3 3224287 N/A 3224307 unspecified role unspecified role prey prey ecolx Escherichia coli N/A 3224309 unspecified role unspecified role bait bait UBAN domain Region 465-520 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false Q9WUU8:p.Asp485Ala D485A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli direct interaction direct interaction false false false rbck1-rnf31-30 3224288 N/A 3224304 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3224308 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false ikbkg-ub-5 3224289 N/A 3224311 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false human Homo sapiens Human N/A 3224307 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false rnf31-sharpin-7 3224290 N/A 3224305 unspecified role unspecified role prey prey GFP-tag GFP-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false Q9H0F6:p.Ile272Ala I272A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false region Δ233-304 required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human N/A 3224308 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false rbck1-ub-1 3224291 N/A 3224304 unspecified role unspecified role bait bait NZF domain Region 191-223 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3224307 unspecified role unspecified role prey prey ecolx Escherichia coli direct interaction direct interaction false false false rnf31-ub-2 3224292 N/A 3224308 unspecified role unspecified role unspecified role unspecified role NZF1 domain Region 350-379 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3224307 unspecified role unspecified role unspecified role unspecified role ile44ala I44A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false sharpin-rbck1-10 3224293 N/A 3224304 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3224305 unspecified role unspecified role bait bait GFP-tag GFP-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3224308 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human association association false false false ub-tnip1-2 3224294 N/A 3224307 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal false ecolx Escherichia coli N/A 3224309 unspecified role unspecified role prey prey Q9WUU8:p.Asp485Ala D485A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false ub-sharpin-2 3224295 N/A 3224305 unspecified role unspecified role prey prey GFP-tag GFP-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false region Δ350-374 required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false region Δ1-232 required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false human Homo sapiens Human N/A 3224307 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal false ecolx Escherichia coli physical association physical association false false false rbck1-ub-2 3224296 N/A 3224304 unspecified role unspecified role unspecified role unspecified role NZF domain Region 191-223 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3224307 unspecified role unspecified role unspecified role unspecified role ile44ala I44A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false ub-rbck1-2 3224297 N/A 3224304 unspecified role unspecified role prey prey region Δ191-223 required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3224307 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal false ecolx Escherichia coli physical association physical association false false false ikbkg-ub-6 3224298 N/A 3224306 unspecified role unspecified role bait bait UBAN domain Region 250-339 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3224307 unspecified role unspecified role prey prey ecolx Escherichia coli direct interaction direct interaction false false false sharpin-rnf31-6 3224299 N/A 3224305 unspecified role unspecified role bait bait GFP-tag GFP-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3224308 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false sharpin-ub-2 3224300 N/A 3224305 unspecified role unspecified role unspecified role unspecified role NZF domain Region 340-387 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3224307 unspecified role unspecified role unspecified role unspecified role ile44ala I44A mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false