DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ sayan-2010-1 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. DIP original experiment: DIP-254158X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2. Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. Only protein-protein interactions imex curation sayan-2010-2 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. DIP original experiment: DIP-254156X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2. Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. Only protein-protein interactions imex curation sayan-2010-3 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. DIP original experiment: DIP-254162X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2. Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. Only protein-protein interactions imex curation sayan-2010-4 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. DIP original experiment: DIP-254160X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2. Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. Only protein-protein interactions imex curation sayan-2010-5 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. DIP original experiment: DIP-254159X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2. Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. Only protein-protein interactions imex curation sayan-2010-6 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. DIP original experiment: DIP-254157X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2. Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. Only protein-protein interactions imex curation sayan-2010-7 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. DIP original experiment: DIP-254163X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2. Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. Only protein-protein interactions imex curation sayan-2010-8 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. DIP original experiment: DIP-254161X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx Differential control of TAp73 and DeltaNp73 protein stability by the ring finger ubiquitin ligase PIR2. Sayan BS., Yang AL., Conforti F., Tucci P., Piro MC., Browne GJ., Agostini M., Bernardini S., Knight RA., Mak TW., Melino G. Only protein-protein interactions imex curation o15350-2 Tumor protein p73 TP73 P73 p53-like transcription factor p53-related protein protein protein human Homo sapiens Human MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVRTWGP Produced by alternative splicing of isoform Alpha. r144b_human E3 ubiquitin-protein ligase RNF144B RNF144B IBRDC2 P53RFP RING finger protein 144B IBR domain-containing protein 2 p53-inducible RING finger protein protein protein human Homo sapiens Human MGSAGRLHYLAMTAENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTLQEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAEVSCRDSQPIVLPTEHRALFGTDAEAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDNDIFLRHYDKGPCRNKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCIICCVCKSCRGKKKKHDPSTT p73_human Tumor protein p73 TP73 P73 p53-like transcription factor p53-related protein protein protein human Homo sapiens Human MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLGALKIPEQYRMTIWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGELQRQRVMEAVHFRVRHTITIPNRGGPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH ubiq_human UBIQ_HUMAN protein protein human Homo sapiens Human MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG o15350-8 Tumor protein p73 TP73 P73 p53-like transcription factor p53-related protein protein protein human Homo sapiens Human MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLGALKIPEQYRMTIWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGELQRQRVMEAVHFRVRHTITIPNRGGPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH Produced by alternative promoter usage. o15350-3 Tumor protein p73 TP73 P73 p53-like transcription factor p53-related protein protein protein human Homo sapiens Human MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPPRDAQQPWPRSASQQRRDEQQPQRPVHGLGVPLHSATPLPRRPQPRQFFNRIGVSKLHRVFHLPRVTEHLPPAEPDH Produced by alternative splicing of isoform Alpha. The splicing of exon 11 results in a frameshift from the original reading frame. rnf144b-tp73-1 3211086 N/A 3211094 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false human Homo sapiens Human N/A 3211095 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false rnf144b-tp73-2 3211087 N/A 3211096 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3211095 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false tp73-ub-4 3211088 N/A 3211097 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal false human Homo sapiens Human N/A 3211096 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false rnf144b-tp73-3 3211089 N/A 3211098 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false human Homo sapiens Human N/A 3211095 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false rnf144b-tp73-4 3211090 N/A 3211099 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false human Homo sapiens Human N/A 3211095 unspecified role unspecified role bait bait Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false tp73-rnf144b-1 3211091 N/A 3211096 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3211095 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false tp73-ub-5 3211092 N/A 3211097 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal false human Homo sapiens Human N/A 3211098 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false human Homo sapiens Human physical association physical association false false false tp73-rnf144b-2 3211093 N/A 3211098 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false human Homo sapiens Human N/A 3211095 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false