DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ alvarez-2010-1 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Alvarez SE., Harikumar KB., Hait NC., Allegood J., Strub GM., Kim EY., Maceyka M., Jiang H., Luo C., Kordula T., Milstien S., Spiegel S. DIP original experiment: DIP-220746X Nature 2010 IMEx Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Alvarez SE., Harikumar KB., Hait NC., Allegood J., Strub GM., Kim EY., Maceyka M., Jiang H., Luo C., Kordula T., Milstien S., Spiegel S. Only protein-protein interactions imex curation alvarez-2010-2 in vitro In vitro comigration in sds comigration in sds page comigration in sds predetermined predetermined participant predetermined Alvarez SE., Harikumar KB., Hait NC., Allegood J., Strub GM., Kim EY., Maceyka M., Jiang H., Luo C., Kordula T., Milstien S., Spiegel S. DIP original experiment: DIP-220749X Nature 2010 IMEx Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Alvarez SE., Harikumar KB., Hait NC., Allegood J., Strub GM., Kim EY., Maceyka M., Jiang H., Luo C., Kordula T., Milstien S., Spiegel S. Only protein-protein interactions imex curation alvarez-2010-3 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip anti tag western anti tag western blot anti tag western Alvarez SE., Harikumar KB., Hait NC., Allegood J., Strub GM., Kim EY., Maceyka M., Jiang H., Luo C., Kordula T., Milstien S., Spiegel S. DIP original experiment: DIP-220747X Nature 2010 IMEx Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Alvarez SE., Harikumar KB., Hait NC., Allegood J., Strub GM., Kim EY., Maceyka M., Jiang H., Luo C., Kordula T., Milstien S., Spiegel S. Only protein-protein interactions imex curation alvarez-2010-4 in vitro In vitro comigration in sds comigration in sds page comigration in sds predetermined predetermined participant predetermined Alvarez SE., Harikumar KB., Hait NC., Allegood J., Strub GM., Kim EY., Maceyka M., Jiang H., Luo C., Kordula T., Milstien S., Spiegel S. DIP original experiment: DIP-220748X Nature 2010 IMEx Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Alvarez SE., Harikumar KB., Hait NC., Allegood J., Strub GM., Kim EY., Maceyka M., Jiang H., Luo C., Kordula T., Milstien S., Spiegel S. Only protein-protein interactions imex curation ubiq_human UBIQ_HUMAN protein protein human Homo sapiens Human MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG ripk1_human Receptor-interacting serine/threonine-protein kinase 1 RIPK1 RIP Cell death protein RIP RIP1 Receptor-interacting protein 1 protein protein human Homo sapiens Human MQPDMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELREVDGTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQQLIMCIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLEESVEEDVKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGMGPVEESWFAPSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREEERRRRVSHDPFAQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNGLYSSHGFGTRPLDPGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPTDESIKYTIYNSTGIQIGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLTDKHLDPIRENLGKHWKNCARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGIKGATVGKLAQALHQCSRIDLLSSLIYVSQN traf2_human TNF receptor-associated factor 2 TRAF2 TRAP3 Tumor necrosis factor type 2 receptor-associated protein 3 E3 ubiquitin-protein ligase TRAF2 RING-type E3 ubiquitin transferase TRAF2 protein protein human Homo sapiens Human MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHHEVCPKFPLTCDGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIGLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL ripk1-ub-1 3210542 N/A 3210546 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3210547 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false traf2-ub-1 3210543 N/A 3210548 unspecified role unspecified role unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm N/A 3210546 unspecified role unspecified role unspecified role unspecified role direct interaction direct interaction false false false ripk1-ub-2 3210544 N/A 3210546 unspecified role unspecified role prey prey HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal n-terminal n-terminal position amino-terminus n-terminus n-term n-term amino-terminus n-terminus n-terminal false human Homo sapiens Human N/A 3210547 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false ripk1-ub-3 3210545 N/A 3210546 unspecified role unspecified role unspecified role unspecified role N/A 3210547 unspecified role unspecified role unspecified role unspecified role human Homo sapiens Human direct interaction direct interaction false false false