DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ du-2010-1 rat Rattus norvegicus (Rat) Rat anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Du J., Wei Y., Liu L., Wang Y., Khairova R., Blumenthal R., Tragon T., Hunsberger JG., Machado-Vieira R., Drevets W., Wang YT., Manji HK. DIP original experiment: DIP-219842X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors. Du J., Wei Y., Liu L., Wang Y., Khairova R., Blumenthal R., Tragon T., Hunsberger JG., Machado-Vieira R., Drevets W., Wang YT., Manji HK. Only protein-protein interactions imex curation du-2010-2 in vitro In vitro protein kinase assay protein kinase assay predetermined predetermined participant predetermined Du J., Wei Y., Liu L., Wang Y., Khairova R., Blumenthal R., Tragon T., Hunsberger JG., Machado-Vieira R., Drevets W., Wang YT., Manji HK. DIP original experiment: DIP-219845X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors. Du J., Wei Y., Liu L., Wang Y., Khairova R., Blumenthal R., Tragon T., Hunsberger JG., Machado-Vieira R., Drevets W., Wang YT., Manji HK. Only protein-protein interactions imex curation du-2010-3 rat Rattus norvegicus (Rat) Rat anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Du J., Wei Y., Liu L., Wang Y., Khairova R., Blumenthal R., Tragon T., Hunsberger JG., Machado-Vieira R., Drevets W., Wang YT., Manji HK. DIP original experiment: DIP-219843X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors. Du J., Wei Y., Liu L., Wang Y., Khairova R., Blumenthal R., Tragon T., Hunsberger JG., Machado-Vieira R., Drevets W., Wang YT., Manji HK. Only protein-protein interactions imex curation du-2010-4 in vitro In vitro protein kinase assay protein kinase assay predetermined predetermined participant predetermined Du J., Wei Y., Liu L., Wang Y., Khairova R., Blumenthal R., Tragon T., Hunsberger JG., Machado-Vieira R., Drevets W., Wang YT., Manji HK. DIP original experiment: DIP-219844X Proceedings of the National Academy of Sciences of the United States of America 2010 IMEx A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors. Du J., Wei Y., Liu L., Wang Y., Khairova R., Blumenthal R., Tragon T., Hunsberger JG., Machado-Vieira R., Drevets W., Wang YT., Manji HK. Only protein-protein interactions imex curation gria2_rat Glutamate receptor 2 Gria2 Glur2 GluR-B GluR-K2 Glutamate receptor ionotropic, AMPA 2 AMPA-selective glutamate receptor 2 protein protein rat Rattus norvegicus (Rat) Rat MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNPQNINPSSSQNSQNFATYKEGYNVYGIESVKI gria1_rat Glutamate receptor 1 Gria1 GluR-A GluR-K1 Glutamate receptor ionotropic, AMPA 1 AMPA-selective glutamate receptor 1 Glur1 protein protein rat Rattus norvegicus (Rat) Rat MPYIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRTSDSRDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASGGGGSGENGRVVSQDFPKSMQSIPCMSHSSGMPLGATGL b2gv74_rat Kinesin light chain Klc2 Klc2_predicted rCG_48462 protein protein rat Rattus norvegicus (Rat) Rat MATMVLPREEKLSQDEIVLGTKAVIQGLETLRGEHRALLAPLASHEAGEAEPGSQERCLLLRRSLEAIELGLGEAQVILALSSHLGAVESEKQKLRAQVRRLVQENQWLREELAGTQQKLQRSEQAVAQLEEEKQHLLFMSQIRKLDEDASPNEEKGDVPKDSLDDLFPNEDEQSPAPSPGGGDVAAQHGGYEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILTRAHEKEFGSVNGENKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGALYRRQGKLEAAHTLEDCASRSRKQGLDPASQTKVVELLKDGSGGRGDRRGSRDVAGGAGPRSESDLEESGPAAEWSGDGSGSLRRSGSFGKLRDALRRSSEMLVRKLQGGGPQEPPNSRMKRASSLNFLNKSVEEPVQPGGTGLSDSRTLSSSSMDLSRRSSLVG gsk3b_rat Glycogen synthase kinase-3 beta Gsk3b Serine/threonine-protein kinase GSK3B Factor A protein protein rat Rattus norvegicus (Rat) Rat MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDMWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASPPANATAASDTNAGDRGQTNNAASASASNST mint homomint Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN peptide2 Phosphoglycogen synthase peptide-2 peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) YRRAAVPPSPSLSRHSSPHQSEDEEE tatklcpcdk TAT-KLCpCDK peptide peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) YGRKKRRQRRRLSDSRTLSSSSMDLSRRSSLVG klc2-gria1-1 3209971 N/A 3209975 unspecified role unspecified role prey prey rat Rattus norvegicus (Rat) Rat N/A 3209976 unspecified role unspecified role prey prey rat Rattus norvegicus (Rat) Rat N/A 3209977 unspecified role unspecified role bait bait rat Rattus norvegicus (Rat) Rat association association false false false gsk3b-peptide2-1 3209972 N/A 3209978 enzyme enzyme unspecified role unspecified role ecolx Escherichia coli N/A 3209979 enzyme target enzyme target substrate substrate unspecified role unspecified role in vitro In vitro phosphorylation phosphorylation reaction phosphorylation false false false klc2-gria1-2 3209973 N/A 3209976 unspecified role unspecified role prey prey rat Rattus norvegicus (Rat) Rat N/A 3209977 unspecified role unspecified role bait bait rat Rattus norvegicus (Rat) Rat physical association physical association false false false gsk3b-tatklcpcdk-1 3209974 N/A 3209978 enzyme enzyme unspecified role unspecified role ecolx Escherichia coli N/A 3209980 enzyme target enzyme target substrate substrate unspecified role unspecified role in vitro In vitro phosphorylation phosphorylation reaction phosphorylation false false false