DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ rosenberg-2010-1 picpa Pichia pastoris (Yeast) Yeast Pichia pastoris electron microscopy electron microscopy Electron crystallography Electron cryomicroscopy Electron crystallography Electron cryomicroscopy predetermined predetermined participant predetermined Rosenberg MF., Bikadi Z., Chan J., Liu X., Ni Z., Cai X., Ford RC., Mao Q. DIP original experiment: DIP-216855X Structure (London, England : 1993) 2010 IMEx The human breast cancer resistance protein (BCRP/ABCG2) shows conformational changes with mitoxantrone. Rosenberg MF., Bikadi Z., Chan J., Liu X., Ni Z., Cai X., Ford RC., Mao Q. Only protein-protein interactions imex curation abcg2_human Broad substrate specificity ATP-binding cassette transporter ABCG2 Placenta-specific ATP-binding cassette transporter Breast cancer resistance protein Mitoxantrone resistance-associated protein CDw338 ABCG2 ABCP BCRP BCRP1 MXR Urate exporter ATP-binding cassette sub-family G member 2 protein protein human Homo sapiens Human MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICYRVKLKSGFLPCRKPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGLSGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNERINRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGYFESAGYHCEAYNNPADFFLDIINGDSTAVALNREEDFKATEIIEPSKQDKPLIEKLAEIYVNSSFYKETKAELHQLSGGEKKKKITVFKEISYTTSFCHQLRWVSKRSFKNLLGNPQASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVVEKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFVMMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLSWLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPWGLWKNHVALACMIVIFLTIAYLKLLFLKKYS abcg2-4 3207322 N/A 3207323 unspecified role unspecified role unspecified role unspecified role picpa Pichia pastoris (Yeast) Yeast Pichia pastoris direct interaction direct interaction false false false