DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ chao-2010-1 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Chao LH., Pellicena P., Deindl S., Barclay LA., Schulman H., Kuriyan J. DIP original experiment: DIP-216950X Nature structural & molecular biology 2010 IMEx Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Chao LH., Pellicena P., Deindl S., Barclay LA., Schulman H., Kuriyan J. Only protein-protein interactions imex curation chao-2010-2 in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Chao LH., Pellicena P., Deindl S., Barclay LA., Schulman H., Kuriyan J. DIP original experiment: DIP-216953X Nature structural & molecular biology 2010 IMEx Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Chao LH., Pellicena P., Deindl S., Barclay LA., Schulman H., Kuriyan J. Only protein-protein interactions imex curation chao-2010-3 ecolx Escherichia coli light scattering light scattering predetermined predetermined participant predetermined Chao LH., Pellicena P., Deindl S., Barclay LA., Schulman H., Kuriyan J. DIP original experiment: DIP-216951X Nature structural & molecular biology 2010 IMEx Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Chao LH., Pellicena P., Deindl S., Barclay LA., Schulman H., Kuriyan J. Only protein-protein interactions imex curation chao-2010-4 in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Chao LH., Pellicena P., Deindl S., Barclay LA., Schulman H., Kuriyan J. DIP original experiment: DIP-216952X Nature structural & molecular biology 2010 IMEx Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Chao LH., Pellicena P., Deindl S., Barclay LA., Schulman H., Kuriyan J. Only protein-protein interactions imex curation chao-2010-5 ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Chao LH., Pellicena P., Deindl S., Barclay LA., Schulman H., Kuriyan J. DIP original experiment: DIP-216954X Nature structural & molecular biology 2010 IMEx Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Chao LH., Pellicena P., Deindl S., Barclay LA., Schulman H., Kuriyan J. Only protein-protein interactions imex curation kcc2d_caeel Calcium/calmodulin-dependent protein kinase type II unc-43 Uncoordinated protein 43 K11E8.1 protein protein caeel Caenorhabditis elegans MMNASTKFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKAAISAVKMVTRMSGVLRTSDSTGSVASNGSTTHDASQVAGTSSQPTSPAAEVYPNVLLFNPQKFPRNCVHPFTTHPYYSPKESSKKKLFFTLLFEVCPHTSRSHILLRDNTKNIYHPYHCFTNKMSNYERAAPSSHGSSTTKKIANAIADLVIRRSSPSIRRKTEADVHNSNRNRKVSAPANLQHALVPVIDVVVATGALASSSVDNLSASTSSDLGRNLLNKKEQGPPSTIKESSESSQTIDDNDSEKGGGQLKHENTVVRADGATGIVSSSNSSTASKSSSTNLSAQKQDIVRVTQTLLDAISCKDFETYTRLCDTSMTCFEPEALGNLIEGIEFHRFYFDGNRKNQVHTTMLNPNVHIIGEDAACVAYVKLTQFLDRNGEAHTRQSQESRVWSKKQGRWVCVHVHRSTQPSTNTTVSEF This sequence has been withdrawn from Uniprot. 3231366FFF81A695 calm_chick Calmodulin CALM CAM RCJMB04_24e7 protein protein chick Gallus gallus (Chicken) Chicken MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK ck2n1_rat Calcium/calmodulin-dependent protein kinase II inhibitor 1 Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor alpha protein protein rat Rattus norvegicus (Rat) Rat MSEVLPYGDEKLSPYGDGGDVGQIFSCRLQDTNNFFGAGQSKRPPKLGQIGRSKRVVIEDDRIDDVLKTMTDKAPPGV camkii-2 3203968 N/A 3203973 unspecified role unspecified role unspecified role unspecified role Kinase and regulatory R1 domain Region 1-291 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false calm-camkii-1 3203969 N/A 3203974 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli N/A 3203973 unspecified role unspecified role unspecified role unspecified role Kinase and regulatory domain Region 1-340 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false camkii-3 3203970 N/A 3203973 unspecified role unspecified role unspecified role unspecified role Kinase and regulatory R1 domain Region 1-291 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false camk2n1-camkii-1 3203971 N/A 3203975 unspecified role unspecified role unspecified role unspecified role inhibitory domain Region 42-62 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false in vitro In vitro N/A 3203973 unspecified role unspecified role unspecified role unspecified role Kinase domain Region 1-272 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false camkii-4 3203972 N/A 3203973 unspecified role unspecified role unspecified role unspecified role Kinase and regulatory R1 domain Region 1-289 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false