DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ ehrlich-2009-1 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip ms participant Identification by mass spectrometry ms participant Ehrlich ES., Wang T., Luo K., Xiao Z., Niewiadomska AM., Martinez T., Xu W., Neckers L., Yu XF. DIP original experiment: DIP-216433X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase. Ehrlich ES., Wang T., Luo K., Xiao Z., Niewiadomska AM., Martinez T., Xu W., Neckers L., Yu XF. Only protein-protein interactions imex curation ehrlich-2009-2 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Ehrlich ES., Wang T., Luo K., Xiao Z., Niewiadomska AM., Martinez T., Xu W., Neckers L., Yu XF. DIP original experiment: DIP-216438X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase. Ehrlich ES., Wang T., Luo K., Xiao Z., Niewiadomska AM., Martinez T., Xu W., Neckers L., Yu XF. Only protein-protein interactions imex curation ehrlich-2009-3 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip anti tag western anti tag western blot anti tag western Ehrlich ES., Wang T., Luo K., Xiao Z., Niewiadomska AM., Martinez T., Xu W., Neckers L., Yu XF. DIP original experiment: DIP-216439X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase. Ehrlich ES., Wang T., Luo K., Xiao Z., Niewiadomska AM., Martinez T., Xu W., Neckers L., Yu XF. Only protein-protein interactions imex curation ehrlich-2009-4 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Ehrlich ES., Wang T., Luo K., Xiao Z., Niewiadomska AM., Martinez T., Xu W., Neckers L., Yu XF. DIP original experiment: DIP-216436X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase. Ehrlich ES., Wang T., Luo K., Xiao Z., Niewiadomska AM., Martinez T., Xu W., Neckers L., Yu XF. Only protein-protein interactions imex curation ehrlich-2009-5 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Ehrlich ES., Wang T., Luo K., Xiao Z., Niewiadomska AM., Martinez T., Xu W., Neckers L., Yu XF. DIP original experiment: DIP-216434X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase. Ehrlich ES., Wang T., Luo K., Xiao Z., Niewiadomska AM., Martinez T., Xu W., Neckers L., Yu XF. Only protein-protein interactions imex curation ehrlich-2009-6 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Ehrlich ES., Wang T., Luo K., Xiao Z., Niewiadomska AM., Martinez T., Xu W., Neckers L., Yu XF. DIP original experiment: DIP-216437X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase. Ehrlich ES., Wang T., Luo K., Xiao Z., Niewiadomska AM., Martinez T., Xu W., Neckers L., Yu XF. Only protein-protein interactions imex curation ehrlich-2009-7 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Ehrlich ES., Wang T., Luo K., Xiao Z., Niewiadomska AM., Martinez T., Xu W., Neckers L., Yu XF. DIP original experiment: DIP-216435X Proceedings of the National Academy of Sciences of the United States of America 2009 IMEx Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase. Ehrlich ES., Wang T., Luo K., Xiao Z., Niewiadomska AM., Martinez T., Xu W., Neckers L., Yu XF. Only protein-protein interactions imex curation hspa1a_hspa1b_human-1 HSPA1A_HSPA1B_human molecule set molecule set human Homo sapiens Human P0DMV8,P0DMV9 cul5_human Cullin-5 CUL5 VACM1 Vasopressin-activated calcium-mobilizing receptor 1 protein protein human Homo sapiens Human MATSNLLKNKGSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEITLMGKQGSNKKSNVEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCPELLANYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWLREVGMPADYVNKLARMFQDIKVSEDLNQAFKEMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLFSVNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA erbb2_human Receptor tyrosine-protein kinase erbB-2 p185erbB2 MLN19 Proto-oncogene c-ErbB-2 Tyrosine kinase-type cell surface receptor HER2 Proto-oncogene Neu ERBB2 HER2 NEU NGL Metastatic lymph node gene 19 protein protein protein human Homo sapiens Human MELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAGGMVHHRHRSSSTRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQRYSEDPTVPLPSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLTPQGGAAPQPHPPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPTAENPEYLGLDVPV ubiq_human UBIQ_HUMAN protein protein human Homo sapiens Human MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG cul5-hsp70-1 3295144 N/A 3295151 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3295152 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human Homo sapiens Human physical association physical association false false false cul5-hsp70-2 3295145 N/A 3295151 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3295152 unspecified role unspecified role bait bait HA-tag HA-tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human Homo sapiens Human physical association physical association false false false erbb2-cul5-1 3295146 N/A 3295152 unspecified role unspecified role prey prey Myc-tag Myc-tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human Homo sapiens Human N/A 3295153 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false erbb2-cul5-2 3295147 N/A 3295152 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3295153 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false hsp70-cul5-1 3295148 N/A 3295152 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3295151 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false erbb2-ub-2 3295149 N/A 3295154 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3295153 unspecified role unspecified role bait bait human Homo sapiens Human physical association physical association false false false cul5-hsp70-3 3295150 N/A 3295152 unspecified role unspecified role bait bait human Homo sapiens Human N/A 3295151 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association false false false