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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3178243">
                <names>
                    <shortLabel>cryle-2008-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="18838690" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="wwpdb" dbAc="MI:0805" id="3EJD" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-113431X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15732207" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="wwpdb" dbAc="MI:0805" id="3EJB" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.0805983105" refType="primary-reference" refTypeAc="MI:0358"/>
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                <hostOrganismList>
                    <hostOrganism ncbiTaxId="-1">
                        <names>
                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Cryle MJ., Schlichting I.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-113431X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2008</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Cryle MJ.,  Schlichting I.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3178244">
                <names>
                    <shortLabel>acp_ecoli</shortLabel>
                    <fullName>Acyl carrier protein</fullName>
                    <alias typeAc="MI:0301" type="gene name">acpP</alias>
                    <alias typeAc="MI:0305" type="locus name">b1094</alias>
                    <alias typeAc="MI:0305" type="locus name">JW1080</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Cytosolic-activating factor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Fatty acid synthase acyl carrier protein</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P0A6A8" version="SP_31" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6OLT" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6DFL" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6N3P" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1T8K" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2K92" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1L0H" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6U0J" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2FAE" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3NY7" version="SP_146"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-542566" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EJD" version="SP_146"/>
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                    <secondaryRef db="ensemblbacteria" id="BAA35902" version="SP_146" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031177" secondary="phosphopantetheine binding" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5WKP" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6W98" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009245" secondary="lipid A biosynthetic process" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2FAC" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EJB" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008610" secondary="lipid biosynthetic process" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1ACP" version="SP_146"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1L0I" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6UXE" version="SP_146"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_415612.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6OKG" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2FHS" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042493" secondary="response to drug" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6WIH" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5WGB" version="SP_146"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5VCB" version="SP_146"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009081" version="SP_146"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036736" version="SP_146"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000036" secondary="acyl carrier activity" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6OKF" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5USR" version="SP_146"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="WP_000103754.1"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29374N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000035" secondary="acyl binding" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2K94" version="SP_146"/>
                    <secondaryRef db="ensemblbacteria" id="b1094" version="SP_146" refType="gene"/>
                    <secondaryRef db="ensemblbacteria" id="AAC74178" version="SP_146" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006633" secondary="fatty acid biosynthetic process" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6WI2" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6OKC" version="SP_146"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EJE" version="SP_146"/>
                    <secondaryRef db="ensemblbacteria" id="BAA35902" version="SP_146" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2K93" version="SP_146"/>
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                    <secondaryRef db="ensemblbacteria" id="BAA35902" version="SP_146" refType="transcript"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="83333">
                    <names>
                        <shortLabel>ecoli</shortLabel>
                        <fullName>Escherichia coli (strain K12)</fullName>
                    </names>
                </organism>
                <sequence>MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA</sequence>
            </interactor>
            <interactor id="3178245">
                <names>
                    <shortLabel>bioi_bacsu</shortLabel>
                    <fullName>Biotin biosynthesis cytochrome P450</fullName>
                    <alias typeAc="MI:0301" type="gene name">bioI</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">CYP107H</alias>
                    <alias typeAc="MI:0305" type="locus name">BSU30190</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P53554" version="62" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensemblbacteria" id="CAB14997" version="SP_145" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005506" secondary="iron ion binding" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0020037" secondary="heme binding" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009102" secondary="biotin biosynthetic process" version="SP_145"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001128" version="SP_145"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="WP_004398783.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EJE" version="SP_145"/>
                    <secondaryRef db="ensemblbacteria" id="CAB14997" version="SP_145" refType="transcript"/>
                    <secondaryRef db="ensemblbacteria" id="BSU_30190" version="SP_145" refType="gene"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15732221" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EJB" version="SP_145"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002397" version="SP_145"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-46307N"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EJD" version="SP_145"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017972" version="SP_145"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_390897.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036396" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004497" secondary="monooxygenase activity" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016705" secondary="oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen" version="SP_145"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="224308">
                    <names>
                        <shortLabel>bacsu</shortLabel>
                        <fullName>Bacillus subtilis</fullName>
                    </names>
                </organism>
                <sequence>MTIASSTASSEFLKNPYSFYDTLRAVHPIYKGSFLKYPGWYVTGYEETAAILKDARFKVRTPLPESSTKYQDLSHVQNQMMLFQNQPDHRRLRTLASGAFTPRTTESYQPYIIETVHHLLDQVQGKKKMEVISDFAFPLASFVIANIIGVPEEDREQLKEWAASLIQTIDFTRSRKALTEGNIMAVQAMAYFKELIQKRKRHPQQDMISMLLKGREKDKLTEEEAASTCILLAIAGHETTVNLISNSVLCLLQHPEQLLKLRENPDLIGTAVEECLRYESPTQMTARVASEDIDICGVTIRQGEQVYLLLGAANRDPSIFTNPDVFDITRSPNPHLSFGHGHHVCLGSSLARLEAQIAINTLLQRMPSLNLADFEWRYRPLFGFRALEELPVTFE</sequence>
                <attributeList>
                    <attribute name="crc64">E4AC3AF2637ACE1A</attribute>
                </attributeList>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-9539-1" id="3178246">
                <names>
                    <shortLabel>acpp-p450-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-88239E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15732242" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-9539-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3178243</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3178247">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15732247" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3178244</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="562">
                                <names>
                                    <shortLabel>ecolx</shortLabel>
                                    <fullName>Escherichia coli</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                    <participant id="3178248">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15732246" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3178245</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="562">
                                <names>
                                    <shortLabel>ecolx</shortLabel>
                                    <fullName>Escherichia coli</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
