DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ gonzalez_gutierrez-2008-1 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Gonzalez-Gutierrez G., Miranda-Laferte E., Nothmann D., Schmidt S., Neely A., Hidalgo P. DIP original experiment: DIP-113704X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx The guanylate kinase domain of the beta-subunit of voltage-gated calcium channels suffices to modulate gating. Gonzalez-Gutierrez G., Miranda-Laferte E., Nothmann D., Schmidt S., Neely A., Hidalgo P. Only protein-protein interactions imex curation gonzalez_gutierrez-2008-2 ecolx Escherichia coli density sedimentation cosedimentation through density gradient density sedimentation predetermined predetermined participant predetermined Gonzalez-Gutierrez G., Miranda-Laferte E., Nothmann D., Schmidt S., Neely A., Hidalgo P. DIP original experiment: DIP-113707X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx The guanylate kinase domain of the beta-subunit of voltage-gated calcium channels suffices to modulate gating. Gonzalez-Gutierrez G., Miranda-Laferte E., Nothmann D., Schmidt S., Neely A., Hidalgo P. Only protein-protein interactions imex curation gonzalez_gutierrez-2008-3 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Gonzalez-Gutierrez G., Miranda-Laferte E., Nothmann D., Schmidt S., Neely A., Hidalgo P. DIP original experiment: DIP-113708X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx The guanylate kinase domain of the beta-subunit of voltage-gated calcium channels suffices to modulate gating. Gonzalez-Gutierrez G., Miranda-Laferte E., Nothmann D., Schmidt S., Neely A., Hidalgo P. Only protein-protein interactions imex curation gonzalez_gutierrez-2008-4 ecolx Escherichia coli density sedimentation cosedimentation through density gradient density sedimentation predetermined predetermined participant predetermined Gonzalez-Gutierrez G., Miranda-Laferte E., Nothmann D., Schmidt S., Neely A., Hidalgo P. DIP original experiment: DIP-113705X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx The guanylate kinase domain of the beta-subunit of voltage-gated calcium channels suffices to modulate gating. Gonzalez-Gutierrez G., Miranda-Laferte E., Nothmann D., Schmidt S., Neely A., Hidalgo P. Only protein-protein interactions imex curation gonzalez_gutierrez-2008-5 ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Gonzalez-Gutierrez G., Miranda-Laferte E., Nothmann D., Schmidt S., Neely A., Hidalgo P. DIP original experiment: DIP-113706X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx The guanylate kinase domain of the beta-subunit of voltage-gated calcium channels suffices to modulate gating. Gonzalez-Gutierrez G., Miranda-Laferte E., Nothmann D., Schmidt S., Neely A., Hidalgo P. Only protein-protein interactions imex curation q8vgc3-2 Voltage-dependent L-type calcium channel subunit beta-2 Cacnb2 Cacnlb2 Calcium channel voltage-dependent subunit beta 2 protein protein rat Rattus norvegicus (Rat) Rat MQCCGLVHRRRVRVSRGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVRYSAAQEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPQESFDVILDENQLEDACEHLADYLEAYWKATHPPSSNLPNPLLSRTLATSTLPLSPTLASNSQGSQGDQRTDRSAPRSASQAEEEPCLEPVKKSQHRSSSATHQNHRSGTGRGLSRQETFDSETQESRDSAYVEPKEDYSHEHVDRYVPHREHNHREESHSSNGHRHREPRHRTRDMGRDQDHNECSKQRSRHKSKDRYCDKEGEVISKRRSEAGEWNRDVYIRQ cacb1_rat Voltage-dependent L-type calcium channel subunit beta-1 Cacnb1 Cacnlb1 Calcium channel voltage-dependent subunit beta 1 protein protein rat Rattus norvegicus (Rat) Rat MVQKSGMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQTLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSRTPPNPLLNRTMATAALAVSPAPVSNLQGPYLVSGDQPLDRATGEHASVHEYPGELGQPPGLYPSNHPPGRAGTLWALSRQDTFDADTPGSRNSVYTEPGDSCVDMETDPSEGPGPGDPAGGGTPPARQGSWEEEEDYEEEMTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGQGVYIR p15381-1 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C CACH2 CACN2 CACNL1A1 CCHL1A1 Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle Smooth muscle calcium channel blocker receptor Voltage-gated calcium channel subunit alpha Cav1.2 CACH2A protein protein rabit Oryctolagus cuniculus (Rabbit) Rabbit MLRALVQPATPAYQPLPSHLSAETESTCKGTVVHEAQLNHFYISPGGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGVADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKVMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVVGKPALEEAKEEKIELKSITADGESPPTTKINMDDLQPNESEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPHNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDSRSAFPQTFTTQRPLHISKAGNNQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGSPLSPAVRAQEAAWKLSSKRCHSQESQIAMACQEGASQDDNYDVRIGEDAECCSEPSLLSTEMLSYQDDENRQLAPPEEEKRDIRLSPKKGFLRSASLGRRASFHLECLKRQKNQGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPTSLPRPCATPPATPGSRGWPPQPIPTLRLEGADSSEKLNSSFPSIHCGSWSGENSPCRGDSSAARRARPVSLTVPSQAGAQGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDLTIEEMENAADDILSGGARQSPNGTLLPFVNRRDPGRDRAGQNEQDASGACAPGCGQSEEALADRRAGVSSL cacnb2-1 3177229 N/A 3177234 unspecified role unspecified role unspecified role unspecified role Region 201-422 Region 201-422 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cacnb1-1 3177230 N/A 3177235 unspecified role unspecified role unspecified role unspecified role Region 209-413 Region 209-413 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cacna1c-cacnb2-8 3177231 N/A 3177236 unspecified role unspecified role bait bait Region 422-534 Region 422-534 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false ecolx Escherichia coli N/A 3177234 unspecified role unspecified role prey prey Region 201-422 Region 201-422 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false YFP-tag YFP-tag yfp tag yellow fluorescent protein tag YFP yellow fluorescent protein yellow fluorescent protein YFP yfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false human Homo sapiens Human physical association physical association false false false cacnb2-2 3177232 N/A 3177234 unspecified role unspecified role unspecified role unspecified role Region 201-422 Region 201-422 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false cacnb1-2 3177233 N/A 3177235 unspecified role unspecified role unspecified role unspecified role Region 209-413 Region 209-413 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false