DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ chen-2008-30 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Chen NJ., Chio II., Lin WJ., Duncan G., Chau H., Katz D., Huang HL., Pike KA., Hao Z., Su YW., Yamamoto K., de Pooter RF., Zúñiga-Pflücker JC., Wakeham A., Yeh WC., Mak TW. DIP original experiment: DIP-113336X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors. Chen NJ., Chio II., Lin WJ., Duncan G., Chau H., Katz D., Huang HL., Pike KA., Hao Z., Su YW., Yamamoto K., de Pooter RF., Zúñiga-Pflücker JC., Wakeham A., Yeh WC., Mak TW. Only protein-protein interactions imex curation chen-2008-31 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Chen NJ., Chio II., Lin WJ., Duncan G., Chau H., Katz D., Huang HL., Pike KA., Hao Z., Su YW., Yamamoto K., de Pooter RF., Zúñiga-Pflücker JC., Wakeham A., Yeh WC., Mak TW. DIP original experiment: DIP-113340X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors. Chen NJ., Chio II., Lin WJ., Duncan G., Chau H., Katz D., Huang HL., Pike KA., Hao Z., Su YW., Yamamoto K., de Pooter RF., Zúñiga-Pflücker JC., Wakeham A., Yeh WC., Mak TW. Only protein-protein interactions imex curation chen-2008-32 human Homo sapiens Human anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Chen NJ., Chio II., Lin WJ., Duncan G., Chau H., Katz D., Huang HL., Pike KA., Hao Z., Su YW., Yamamoto K., de Pooter RF., Zúñiga-Pflücker JC., Wakeham A., Yeh WC., Mak TW. DIP original experiment: DIP-113339X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors. Chen NJ., Chio II., Lin WJ., Duncan G., Chau H., Katz D., Huang HL., Pike KA., Hao Z., Su YW., Yamamoto K., de Pooter RF., Zúñiga-Pflücker JC., Wakeham A., Yeh WC., Mak TW. Only protein-protein interactions imex curation chen-2008-33 mouse Mus musculus Mouse comigration in sds comigration in sds page comigration in sds western blot western blot Immuno blot Immuno blot Chen NJ., Chio II., Lin WJ., Duncan G., Chau H., Katz D., Huang HL., Pike KA., Hao Z., Su YW., Yamamoto K., de Pooter RF., Zúñiga-Pflücker JC., Wakeham A., Yeh WC., Mak TW. DIP original experiment: DIP-113337X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx f.2d experiment includes only mouse proteins Chen NJ., Chio II., Lin WJ., Duncan G., Chau H., Katz D., Huang HL., Pike KA., Hao Z., Su YW., Yamamoto K., de Pooter RF., Zúñiga-Pflücker JC., Wakeham A., Yeh WC., Mak TW. Only protein-protein interactions imex curation chen-2008-34 human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Chen NJ., Chio II., Lin WJ., Duncan G., Chau H., Katz D., Huang HL., Pike KA., Hao Z., Su YW., Yamamoto K., de Pooter RF., Zúñiga-Pflücker JC., Wakeham A., Yeh WC., Mak TW. DIP original experiment: DIP-113341X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors. Chen NJ., Chio II., Lin WJ., Duncan G., Chau H., Katz D., Huang HL., Pike KA., Hao Z., Su YW., Yamamoto K., de Pooter RF., Zúñiga-Pflücker JC., Wakeham A., Yeh WC., Mak TW. Only protein-protein interactions imex curation chen-2008-35 mouse Mus musculus Mouse anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Chen NJ., Chio II., Lin WJ., Duncan G., Chau H., Katz D., Huang HL., Pike KA., Hao Z., Su YW., Yamamoto K., de Pooter RF., Zúñiga-Pflücker JC., Wakeham A., Yeh WC., Mak TW. DIP original experiment: DIP-113338X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors. Chen NJ., Chio II., Lin WJ., Duncan G., Chau H., Katz D., Huang HL., Pike KA., Hao Z., Su YW., Yamamoto K., de Pooter RF., Zúñiga-Pflücker JC., Wakeham A., Yeh WC., Mak TW. Only protein-protein interactions imex curation traf2_mouse TNF receptor-associated factor 2 Traf2 E3 ubiquitin-protein ligase TRAF2 RING-type E3 ubiquitin transferase TRAF2 protein protein mouse Mus musculus Mouse MAAASVTSPGSLELLQPGFSKTLLGTRLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLEVHYEVCPKFPLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHNNREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL ripk1_mouse Receptor-interacting serine/threonine-protein kinase 1 Cell death protein RIP Receptor-interacting protein 1 Ripk1 Rinp Rip protein protein mouse Mus musculus Mouse MQPDMSLDNIKMASSDLLEKTDLDSGGFGKVSLCYHRSHGFVILKKVYTGPNRAEYNEVLLEEGKMMHRLRHSRVVKLLGIIIEEGNYSLVMEYMEKGNLMHVLKTQIDVPLSLKGRIIVEAIEGMCYLHDKGVIHKDLKPENILVDRDFHIKIADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYMAPEHLNDINAKPTEKSDVYSFGIVLWAIFAKKEPYENVICTEQFVICIKSGNRPNVEEILEYCPREIISLMERCWQAIPEDRPTFLGIEEEFRPFYLSHFEEYVEEDVASLKKEYPDQSPVLQRMFSLQHDCVPLPPSRSNSEQPGSLHSSQGLQMGPVEESWFSSSPEYPQDENDRSVQAKLQEEASYHAFGIFAEKQTKPQPRQNEAYNREEERKRRVSHDPFAQQRARENIKSAGARGHSDPSTTSRGIAVQQLSWPATQTVWNNGLYNQHGFGTTGTGVWYPPNLSQMYSTYKTPVPETNIPGSTPTMPYFSGPVADDLIKYTIFNSSGIQIGNHNYMDVGLNSQPPNNTCKEESTSRHQAIFDNTTSLTDEHLNPIRENLGRQWKNCARKLGFTESQIDEIDHDYERDGLKEKVYQMLQKWLMREGTKGATVGKLAQALHQCCRIDLLNHLIRASQS tnr1a_mouse Tumor necrosis factor receptor superfamily member 1A p60 Tumor necrosis factor receptor 1 Tumor necrosis factor receptor type I p55 Tnfrsf1a Tnfr1 Tnfr-1 protein protein mouse Mus musculus Mouse MGLPTVPGLLLSLVLLALLMGIHPSGVTGLVPSLGDREKRDSLCPQGKYVHSKNNSICCTKCHKGTYLVSDCPSPGRDTVCRECEKGTFTASQNYLRQCLSCKTCRKEMSQVEISPCQADKDTVCGCKENQFQRYLSETHFQCVDCSPCFNGTVTIPCKETQNTVCNCHAGFFLRESECVPCSHCKKNEECMKLCLPPPLANVTNPQDSGTAVLLPLVILLGLCLLSFIFISLMCRYPRWRPEVYSIICRDPVPVKEEKAGKPLTPAPSPAFSPTSGFNPTLGFSTPGFSSPVSSTPISPIFGPSNWHFMPPVSEVVPTQGADPLLYESLCSVPAPTSVQKWEDSAHPQRPDNADLAILYAVVDGVPPARWKEFMRFMGLSEHEIERLEMQNGRCLREAQYSMLEAWRRRTPRHEDTLEVVGLVLSKMNLAGCLENILEALRNPAPSSTTRLPR tradd_mouse Tumor necrosis factor receptor type 1-associated DEATH domain protein Tradd TNFRSF1A-associated via death domain protein protein mouse Mus musculus Mouse MAAGQNGHEEWVGSAYLFLESAVDKVILSEAYTDPKKKVAIYKALQTALSESGDSSDVLQILKIHCSDPQLIVQLRFCGRVLCGRFLQAYREGALRTALQRCMAPALAQEALRLQLELRAGAEQLDSWLTDEERCLNYILAQKPDRLRDEELAELEDELCKLTCDCTGQGGAIQVASAGSKFPVSSPTEEKPLPAACQTFLFHGQLVVNRPLTLQDQQTFARSVGLKWRRVGRSLQRNCRALRDPALDSLAYEYERDGLYEQAFQLLRRFMQAEGRRATLQRLVEALEENELTSLAEDLLGQAEPDGGLA tlr4_mouse Toll-like receptor 4 Tlr4 Lps protein protein mouse Mus musculus Mouse MMPPWLLARTLIMALFFSCLTPGSLNPCIEVVPNITYQCMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWHGLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAHNFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQDQAFQGIKLHELTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVSAMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSGCCSYSDLGTNSLRHLDLSFNGAIIMSANFMGLEELQHLDFQHSTLKRVTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKDNTLSNVFANTTNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNLLFLDSSHYNQLYSLSTLDCSFNRIETSKGILQHFPKSLAFFNLTNNSVACICEHQKFLQWVKEQKQFLVNVEQMTCATPVEMNTSLVLDFNNSTCYMYKTIISVSVVSVIVVSTVAFLIYHFYFHLILIAGCKKYSRGESIYDAFVIYSSQNEDWVRNELVKNLEEGVPRFHLCLHYRDFIPGVAIAANIIQEGFHKSRKVIVVVSRHFIQSRWCIFEYEIAQTWQFLSSRSGIIFIVLEKVEKSLLRQQVELYRLLSRNTYLEWEDNPLGRHIFWRRLKNALLDGKASNPEQTAEEEQETATWT ubiq_mouse Ubiquitin Rps27a Uba80 Ubcep1 Uba52 Ubcep2 Ubb Ubc protein protein mouse Mus musculus Mouse MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG tnfrsf1a-ripk1-6 3176536 N/A 3176542 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3176543 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3176544 unspecified role unspecified role bait bait mouse Mus musculus Mouse association association false false false ripk1-tradd-1 3176537 N/A 3176545 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3176543 unspecified role unspecified role bait bait myc tag myc tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false tradd-ripk1-1 3176538 N/A 3176546 unspecified role unspecified role prey prey myc tag myc tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3176543 unspecified role unspecified role prey prey myc tag myc tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human N/A 3176545 unspecified role unspecified role bait bait human Homo sapiens Human association association false false false ripk1-ub-4 3176539 N/A 3176547 unspecified role unspecified role unspecified role unspecified role mouse Mus musculus Mouse N/A 3176543 unspecified role unspecified role unspecified role unspecified role mouse Mus musculus Mouse covalent binding covalent binding false false false tlr4-tradd-1 3176540 N/A 3176545 unspecified role unspecified role prey prey human Homo sapiens Human N/A 3176546 unspecified role unspecified role bait bait myc tag myc tag myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag predetermined featur predetermined feature predetermined featur n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human physical association physical association false false false tlr4-ripk1-1 3176541 N/A 3176545 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3176543 unspecified role unspecified role prey prey mouse Mus musculus Mouse N/A 3176546 unspecified role unspecified role bait bait mouse Mus musculus Mouse association association false false false