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    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>DIP</shortLabel>
                <fullName>Database of Interacting Proteins</fullName>
            </names>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="primary-reference" refTypeAc="MI:0358"/>
            </xref>
            <attributeList>
                <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
                <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
                <attribute name="postalAddress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
                <attribute name="url">http://dip.doe-mbi.ucla.edu/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="3175487">
                <names>
                    <shortLabel>jayaram-2008-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="18678918" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-111273X" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-9418" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.0804503105" refType="primary-reference" refTypeAc="MI:0358"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15719350" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="562">
                        <names>
                            <shortLabel>ecolx</shortLabel>
                            <fullName>Escherichia coli</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>x-ray diffraction</shortLabel>
                        <fullName>x-ray crystallography</fullName>
                        <alias typeAc="MI:0303" type="go synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">X-ray</alias>
                        <alias typeAc="MI:1041" type="synonym">x-ray diffraction</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1272" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>predetermined</shortLabel>
                        <fullName>predetermined participant</fullName>
                        <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Jayaram H., Accardi A., Wu F., Williams C., Miller C.</attribute>
                    <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-111273X</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2008</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
                    <attribute name="title" nameAc="MI:1091">Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger.</attribute>
                    <attribute name="author-list" nameAc="MI:0636">Jayaram H.,  Accardi A.,  Wu F.,  Williams C.,  Miller C.</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="3175488">
                <names>
                    <shortLabel>clca_ecoli</shortLabel>
                    <fullName>H(+)/Cl(-) exchange transporter ClcA</fullName>
                    <alias typeAc="MI:0301" type="gene name">clcA</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">ClC-ec1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">eriC</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">yadQ</alias>
                    <alias typeAc="MI:0305" type="locus name">JW5012</alias>
                    <alias typeAc="MI:0305" type="locus name">b0155</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P37019" version="92" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4KJQ" version="SP_190"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-9523N" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1OTS" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990451" secondary="cellular stress response to acidic pH" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005247" secondary="voltage-gated chloride channel activity" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2HTK" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2R9H" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902476" secondary="chloride transmembrane transport" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4KJP" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4FTP" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015299" secondary="solute:proton antiporter activity" version="SP_190"/>
                    <secondaryRef db="ensemblbacteria" id="b0155" version="SP_190" refType="gene"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1OTU" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4KK9" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2H2S" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2FEC" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1OTT" version="SP_190"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P77394" version="SP_163" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15719361" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EJZ" version="SP_190"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023861" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1KPK" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4KJW" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4KK8" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6K5D" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5HD8" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EJY" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2FED" version="SP_190"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_414697.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015108" secondary="chloride transmembrane transporter activity" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ADB" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2EZ0" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6AD8" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4LOU" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6LSC" version="SP_190"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="WP_000845394.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902600" secondary="proton transmembrane transport" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4KKA" version="SP_190"/>
                    <secondaryRef db="ensemblbacteria" id="BAB96732" version="SP_190" refType="gene"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2EXY" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2FEE" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4MQX" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2HT2" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4KKB" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3DET" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4KK6" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6V2J" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6AD7" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4KK5" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6K5F" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ADC" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ENE" version="SP_190"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001807" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4KKC" version="SP_190"/>
                    <secondaryRef db="ensemblbacteria" id="AAC73266" version="SP_190" refType="transcript"/>
                    <secondaryRef db="ensemblbacteria" id="BAB96732" version="SP_190" refType="transcript"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4KKL" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2HT4" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0062158" secondary="chloride:proton antiporter activity" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ADA" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3NMO" version="SP_190"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="83333">
                    <names>
                        <shortLabel>ecoli</shortLabel>
                        <fullName>Escherichia coli (strain K12)</fullName>
                    </names>
                </organism>
                <sequence>MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQLARSKAASASENT</sequence>
                <attributeList>
                    <attribute name="crc64">0B1BC39B417E9690</attribute>
                </attributeList>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-9418-1" id="3175489">
                <names>
                    <shortLabel>clc_ec1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="dip" dbAc="MI:0465" id="DIP-88001E" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-9418-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15719425" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>3175487</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3175490">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-15719429" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3175488</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>unspecified role</shortLabel>
                                    <fullName>unspecified role</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <hostOrganismList>
                            <hostOrganism ncbiTaxId="562">
                                <names>
                                    <shortLabel>ecolx</shortLabel>
                                    <fullName>Escherichia coli</fullName>
                                </names>
                            </hostOrganism>
                        </hostOrganismList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
