DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ chen-2007-9 in vitro In vitro comig non denat gel comigration in non denaturing gel electrophoresis comig non denat gel predetermined predetermined participant predetermined Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. DIP original experiment: DIP-66826X Nature structural & molecular biology 2007 IMEx Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40. Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. Only protein-protein interactions imex curation chen-2007-10 in vitro In vitro comig non denat gel comigration in non denaturing gel electrophoresis comig non denat gel predetermined predetermined participant predetermined Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. DIP original experiment: DIP-66822X Nature structural & molecular biology 2007 IMEx Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40. Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. Only protein-protein interactions imex curation chen-2007-11 in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. DIP original experiment: DIP-66821X Nature structural & molecular biology 2007 IMEx Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40. Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. Only protein-protein interactions imex curation chen-2007-12 in vitro In vitro comig non denat gel comigration in non denaturing gel electrophoresis comig non denat gel predetermined predetermined participant predetermined Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. DIP original experiment: DIP-66823X Nature structural & molecular biology 2007 IMEx Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40. Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. Only protein-protein interactions imex curation chen-2007-13 in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. DIP original experiment: DIP-66820X Nature structural & molecular biology 2007 IMEx Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40. Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. Only protein-protein interactions imex curation chen-2007-14 in vitro In vitro comig non denat gel comigration in non denaturing gel electrophoresis comig non denat gel predetermined predetermined participant predetermined Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. DIP original experiment: DIP-66824X Nature structural & molecular biology 2007 IMEx Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40. Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. Only protein-protein interactions imex curation chen-2007-15 in vitro In vitro comig non denat gel comigration in non denaturing gel electrophoresis comig non denat gel predetermined predetermined participant predetermined Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. DIP original experiment: DIP-66825X Nature structural & molecular biology 2007 IMEx Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40. Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. Only protein-protein interactions imex curation chen-2007-16 in vitro In vitro comig non denat gel comigration in non denaturing gel electrophoresis comig non denat gel predetermined predetermined participant predetermined Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. DIP original experiment: DIP-253201X Nature structural & molecular biology 2007 IMEx Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40. Chen Y., Xu Y., Bao Q., Xing Y., Li Z., Lin Z., Stock JB., Jeffrey PD., Shi Y. Only protein-protein interactions imex curation p2r3a_human Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha PPP2R3A PPP2R3 Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B PP2A subunit B isoforms B''-PR72/PR130 PP2A subunit B isoforms B72/B130 PP2A subunit B isoform PR72/PR130 PP2A subunit B isoform R3 isoform protein protein human Homo sapiens Human MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFTHGIDCIVVHHSVCADLLHIPVSQFKDADLNSMFLPHENGLSSAEGDYPQQAFTGIPRVKRGSTFQNTYNLKDIAGEAISFASGKIKEFSFEKLKNSNHAAYRKGRKVKSDSFNRRSVDLDLLCGHYNNDGNAPSFGLLRSSSVEEKPLSHRNSLDTNLTSMFLQNFSEEDLVTQILEKHKIDNFSSGTDIKMCLDILLKCSEDLKKCTDIIKQCIKKKSGSSISEGSGNDTISSSETVYMNVMTRLASYLKKLPFEFMQSGNNEALDLTELISNMPSLQLTPFSPVFGTEQPPKYEDVVQLSASDSGRFQTIELQNDKPNSRKMDTVQSIPNNSTNSLYNLEVNDPRTLKAVQVQSQSLTMNPLENVSSDDLMETLYIEEESDGKKALDKGQKTENGPSHELLKVNEHRAEFPEHATHLKKCPTPMQNEIGKIFEKSFVNLPKEDCKSKVSKFEEGDQRDFTNSSSQEEIDKLLMDLESFSQKMETSLREPLAKGKNSNFLNSHSQLTGQTLVDLEPKSKVSSPIEKVSPSCLTRIIETNGHKIEEEDRALLLRILESIEDFAQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQTPEVIKIQNKPEKKPGTPLPPPATSPSSPRPLSPVPHVNNVVNAPLSINIPRFYFPEGLPDTCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEKCGKLQSVDEE pp2aa_human Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform PPP2CA Replication protein C protein protein human Homo sapiens Human MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL 2aaa_human Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform PPP2R1A PP2A subunit A isoform PR65-alpha PP2A subunit A isoform R1-alpha Medium tumor antigen-associated 61 kDa protein protein protein human Homo sapiens Human MAAADGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLSLA st_sv40 Small t antigen protein protein sv40 sv40 SV40 MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYKKMEDGVKYAHQPDFGGFWDATEVFASSLNPGVDAMYCKQWPECAKKMSANCICLLCLLRMKHENRKLYRKDPLVWVDCYCFDCFRMWFGLDLCEGTLLLWCDIIGQTTYRDLKL 91EC925ED2E29668 q13362-2 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform PPP2R5C KIAA0044 PP2A B subunit isoform B'-gamma PP2A B subunit isoform B56-gamma PP2A B subunit isoform PR61-gamma PP2A B subunit isoform R5-gamma Renal carcinoma antigen NY-REN-29 protein protein human Homo sapiens Human MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPSSNPTGAEFDPEEDEPTLEAAWPHLQLVYEFFLRFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNEYIMSLISDNAAKILPIMFPSLYRNSKTHWNKTIHGLIYNALKLFMEMNQKLFDDCTQQFKAEKLKEKLKMKEREEAWVKIENLAKANPQVLKKRIT 2aba_human Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform PPP2R2A PP2A subunit B isoform alpha PP2A subunit B isoform B55-alpha PP2A subunit B isoform PR55-alpha PP2A subunit B isoform R2-alpha protein protein human Homo sapiens Human MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN ppp2ca-ppp2r1a-12 3156957 N/A 3156965 unspecified role unspecified role neutral component neutral component 165-529 binding region 165-529 binding region sufficient to bind sufficient binding region sufficient to bind predetermined featur predetermined feature predetermined featur certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3156966 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli N/A 3156967 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli direct interaction direct interaction false false false ppp2ca-ppp2r1a-13 3156958 N/A 3156966 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli N/A 3156967 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli direct interaction direct interaction false false false ppp2r1a-st-2 3156959 N/A 3156967 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli N/A 3156968 unspecified role unspecified role neutral component neutral component 87-174 binding region 87-174 binding region sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false ppp2ca-ppp2r1a-14 3156960 N/A 3156968 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli N/A 3156966 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli N/A 3156967 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli physical association physical association false false false ppp2r1a-st-3 3156961 N/A 3156967 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli N/A 3156968 unspecified role unspecified role neutral component neutral component 87-174 binding region 87-174 binding region sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false ppp2ca-ppp2r1a-15 3156962 N/A 3156969 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli N/A 3156966 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli N/A 3156967 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli physical association physical association false false false ppp2ca-ppp2r1a-16 3156963 N/A 3156970 unspecified role unspecified role neutral component neutral component spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm N/A 3156966 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli N/A 3156967 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli physical association physical association false false false ppp2ca-ppp2r1a-17 3156964 N/A 3156969 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli N/A 3156966 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli N/A 3156967 unspecified role unspecified role neutral component neutral component ecolx Escherichia coli physical association physical association false false false 1 nodeMerge04 2013-08-12