DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ aguilar-2006-1 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262683X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-2 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262679X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-3 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262670X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-4 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262675X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-5 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262688X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-6 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262680X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-7 in vitro In vitro pull down pull down predetermined predetermined participant predetermined Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262684X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-8 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262671X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-9 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262676X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-10 in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262691X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-11 in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262687X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-12 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262689X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-13 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262672X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-14 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262677X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-15 in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262681X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-16 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262690X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-17 in vitro In vitro pull down pull down anti tag western anti tag western blot anti tag western Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262682X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-18 in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262686X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-19 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262673X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-20 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262678X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-21 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262674X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation aguilar-2006-22 in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. DIP original experiment: DIP-262685X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Epsin N-terminal homology domains perform an essential function regulating Cdc42 through binding Cdc42 GTPase-activating proteins. Aguilar RC., Longhi SA., Shaw JD., Yeh LY., Kim S., Schön A., Freire E., Hsu A., McCormick WK., Watson HA., Wendland B. Only protein-protein interactions imex curation rga1_yeast Rho-type GTPase-activating protein 1 RGA1 DBM1 THE1 YOR127W O3290 YOR3290W protein protein yeast Saccharomyces cerevisiae Baker's yeast MASTAPNEQFPSCVRCKEFITTGHAYELGCDRWHTHCFACYKCEKPLSCESDFLVLGTGALICFDCSDSCKNCGKKIDDLAIILSSSNEAYCSDCFKCCKCGENIADLRYAKTKRGLFCLSCHEKLLAKRKYYEEKKRRLKKNLPSLPTPVIDNGHTDEVSASAVLPEKTFSRPASLVNEIPSGSEPSKDIETNSSDIVPHFITGYNDSDDNSGSSKFGSNVSIDVIGPEENSTEHVNDDVKEEAEAPSANMSLNVATDPTLSCKEPPSHSRNLLNKTPLRNSSGQYLAKSPSSYRQGIIVNDSLEESDQIDPPNNSSRNASELLTSVLHSPVSVNMKNPKGSNTDIFNTGEISQMDPSLSRKVLNNIVEETNALQRPVVEVVKEDRSVPDLAGVQQEQAEKYSYSNNSGKGRKISRSLSRRSKDLMINLKSRATGKQDSNVKLSPASKVTSRRSQDLMRDNDSHTGLDTPNSNSTSLDILVNNQKSLNYKRFTDNGTLRVTSGKETALEEQKNHSFKSPSPIDHLLQSPATPSNVSMYRTPPLDSSLTFDRRNGSSYSNQNYSIPSWQKTPKTQLENSDNFEEQKETLYENSESRNDPSLDKEIVTAEHYLKQLKINLKELESQREELMKEITEMKSMKEALRRHIESYNSEKNKLYLDSNELSNNPPMINEISLGESPPVKHVATASSVARSSVKPKFWKFFSSAKPQTEQSIQGVSTNNTNSIVKSAPVLLSAPSSGSNSGRLEISPPVLQNPNEFSDVRLVPIENDANMGQSKDGEEYLDGSNLYGSSLVARCNYENNEIPMILSVCIDFIESDEENMRSEGIYRKSGSQLVIEEIEKQFSAWKVQQNTETPNILTEQDLNVVTGVLKRYLRKLPNPIFTFQIYEPLMRLVKSKKMMENLPFVGGKLSLEAKNSDTYMSSKSALKNILEDLPREHYRVLRVLSEHIEKVTRYSHWNRMTLYNLALVFAPGLIRDFSGEKDIIDMKERNYIVAFIFGNYKDILT C805411B57553791 ent1_yeast Epsin-1 ENT1 YDL161W protein protein yeast Saccharomyces cerevisiae Baker's yeast MSKQFVRSAKNLVKGYSSTQVLVRNATSNDNHQVSKDSLIELAEKSYDSADFFEIMDMLDKRLNDKGKYWRHIAKALTVIDYLIRFGSENCVLWCRENLYIIKTLKEFRHEDDEGIDQGQIVRVKAKELTALLSDDERLNEERNMNIKGRNRKGRRRRGTGRSDENDDDLQRAISASRLTAEEDERRRKQDEDYETALQLSKEEEELKRLQDLQRMQQQQGQQQLQQPMYYDIFGNPITPEEYAQFQLQQQQQQQQQQLQQQPMYYDVFGNPITPEELAQFQQQQQLQEQQYLASMQQQQQAMSNNPFAKSEQSSSSPKRNQLVAASSPQQLQQQKQQEPLIQNRTGNQSMTDKYSKLNELLATGTGIDTFGNVGEARIPAQHTKTGTFINSQGTGYRQVSDDPNHNPFLNSQYTGLPSTSVVPTQTGYGFGNQSQQQSQNNGSNNRGYTLIDL 37447FB4A6449256 ent2_yeast Epsin-2 YLR206W ENT2 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSKQFVRSAKNMMKGYSSTQVLVRDATANDSRTPSIDTLDDLAQRSYDSVDFFEIMDMLDKRLNDKGKYWRHVAKSLTVLDYLVRFGSENCVLWCRENFYVIKTLREFRHENESGFDEGQIIRVKAKELVSLLNDEERLREERSMNTRNRRANRAARPRPRRQRTRSNPHDSSPSYQDDLEKALEESRITAQEDEQRRRELAQYDDEDPDFQAALQLSKEEEELKQLQELQRLQKQQQSLSQFQAPLQQQQPQQQPAYYDIFGNPISQDEYLQYQYQQDQEQAMAQQRWLDQQQEQQQLAEQQYFQQQQQAAAAASALQQQQTAANMQQQQQQPADFQQPLPTGSNNPFSMDNLERQKQEQQHAQLQRQQEEARQQQEQLKLQQLQRQQQEEAQLHQKRQEEAQLQQQQAQLLQQQAQFQQQQPLKQTRTGNQSISDKYSDLNTLLATGTGIDTFGNTGEARIPAQHTKTGTFINSQGTGYKQVTNEPKNNPFLSNQYTGLPSTNIVPTQTGYGFGNQPQSPPTNSPQQNPTGISYSQPQQQQQPQQQPQYMQNFQQQQPQYAQNFQQQPQYTQNYQQQPQYIQPHQQQQQQQQQQQQQQGYTPDQGVSLIDL CEC1B2D04C0F7D86 epn1_rat Epsin-1 Epn1 EPS-15-interacting protein 1 protein protein rat Rattus norvegicus (Rat) Rat MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQPPSCGPEDDVQLQLALSLSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTTPAPPQASDPWGGPASVPTAVPVAAAASDPWGAPAVPPAADPWGGAAPTPASGDPWRPAAPTGPSVDPWGGTPAPAAGEGPTSDPWGSADGGAPVSGPPSSDPWAPAPAFSDPWGGSPAKPSSNGTAVGGFDTEPDEFSDFDRLRTALPTSGSSTGELELLAGEVPARSPGAFDMSGVGGSLAESVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPSGAPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL mint Binds to membranes enriched in phosphatidylinositol-4,5-biphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis bem3_yeast GTPase-activating protein BEM3 Bud emergence protein 3 BEM3 YPL115C LPH12C protein protein yeast Saccharomyces cerevisiae Baker's yeast MTDNLTTTHGGSTTLELLAQYNDHRSKKDKSIEHIEKGTCSGKERNPSYDEIFTENIKLKLQVQEYETEIESLEKVIDMLQKNREASLEVVLEQVQNDSRDSYVNDQSFVLPPRSAERKAHIKSLNLPIPTLSPPLQQGSDVALETSVTPTVPQIGVTSNTSISRKHLQNMILNDEIEANSSFSSPKIINRSVSSPTKIHSEQLASPAASVTYTTSRITIKSPNKGSKSPLQERLRSPQNPNRMTAVINNHLHSPLKASTSNNLDELTESKSQQLTNDAIQKNDRVYSSITSSAYTTGTPTSAAKSPSSLLEVKEGENKALGFSPASKEKLDDFTQLLDSSFGEEDLVNTDSKDPLSIKSTINESLPPPPAPPTFFSPTSSGNIKNSTPLSSHLASPVILNKKDDNFGAQSAKNLKKPVLTSSLPNLSTKLSTTSQNASLPPNPPVESSSKQKQLGETASIHSTNTLNTFSSTPQGSLKTLRRPHASSVSTVKSVAQSLKSDIPLFVQPEDFGTIQIEVLSTLYRDNEDDLSILIAIIDRKSGKEMFKFSKSIHKVRELDVYMKSHVPDLPLPTLPDRQLFQTLSPTKVDTRKNILNQYYTSIFSVPEFPKNVGLKIAQFISTDTVMTPPMMDDNVKDGSLLLRRPKTLTGNSTWRVRYGILRDDVLQLFDKNQLTETIKLRQSSIELIPNLPEDRFGTRNGFLITEHKKSGLSTSTKYYICTETSKERELWLSAFSDYIDPSQSLSLSSSRNANDTDSASHLSAGTHHSKFGNATISATDTPSYVTDLTQEYNNNNNISNSSNNIANSDGIDSNPSSHSNFLASSSGNAEEEKDSRRAKMRSLFPFKKLTGPASAMNHIGITISNDSDSPTSPDSIIKSPSKKLMEVSSSSNSSTGPHVSTAIFGSSLETCLRLSSHKYQNVYDLPSVVYRCLEYLYKNRGIQEEGIFRLSGSSTVIKTLQERFDKEYDVDLCRYNESIEAKDDEASPSLYIGVNTVSGLLKLYLRKLPHLLFGDEQFLSFKRVVDENHNNPVQISLGFKELIESGLVPHANLSLMYALFELLVRINENSKFNKMNLRNLCIVFSPTLNIPISMLQPFITDFACIFQGGEPVKEEEREKVDIHIPQV 4BF03EAD6EF10283 rga2_yeast Rho-type GTPase-activating protein 2 RGA2 D9481.4 YDR379W protein protein yeast Saccharomyces cerevisiae Baker's yeast MSADPINDQSSLCVRCNKSIASSQVYELESKKWHDQCFTCYKCDKKLNADSDFLVLDIGTLICYDCSDKCTNCGDKIDDTAIILPSSNEAYCSNCFRCCRCSNRIKNLKYAKTKRGLCCMDCHEKLLRKKQLLLENQTKNSSKEDFPIKLPERSVKRPLSPTRINGKSDVSTNNTAISKNLVSSNEDQQLTPQVLVSQERDESSLNDNNDNDNSKDREETSSHARTVSIDDILNSTLEHDSNSIEEQSLVDNEDYINKMGEDVTYRLLKPQRANRDSIVVKDPRIPNSNSNANRFFSIYDKEETDKDDTDNKENEIIVNTPRNSTDKITSPLNSPMAVQMNEEVEPPHGLALTLSEATKENNKSSQGIQTSTSKSMNHVSPITRTDTVEMKTSTSSSTLRLSDNGSFSRPQTADNLLPHKKVAPSPNKKLSRSFSLKSKNFVHNLKSKTSEMLDPKHPHHSTSIQESDTHSGWGVSSTHTNIRKSKAKKNPVSRGQSDSTIYNTLPQHGNFTVPEFNHKKAQSSLGSISKKQNSNDTATNRRINGSFTSSSSGHHIAMFRTPPLESGPLFKRPSLSSESAHHRSSSLQTSRSTNALLEDDSTKVDATDESATSLEKDFYFTELTLRKLKLDVRELEGTKKKLLQDVENLRLAKERLLNDVDNLTREKDKQSASSRESLEQKENIATSITVKSPSSNSDRKGSISNASPKPRFWKIFSSAKDHQVGDLESQQRSPNSSSGGTTNIAQKEISSPKLIRVHDELPSPGKVPLSPSPKRLDYTPDGSHLYGSSLQARCAYEKSTVPIIIRCCIDRIEKDDIGLNMEGLYRKSGSQTLVEEIENEFAQNNSLHSDTLSPKLNALLNQDIHAVASVLKRYLRKLPDPVLSFSIYDALIDLVRNNQLIERLPLNNDKFLDSPQKVTIYEMVLKSLLEIFKILPVEHQEVLKVLAAHIGKVRRCSERNLMNLHNLSLVFAPSLIHDFDGEKDIVDMKERNYIVEFILGNYRDIFKQA FA13BA1DF8B35D98 fir1_yeast Factor interacting with REF2 FIR1 PIP1 Polymerase-interacting protein 1 PAP1-interacting protein YER032W protein protein yeast Saccharomyces cerevisiae Baker's yeast MSLPVTPVKSKVCSTLSIQHEMDHDQCRDVLCPRENLLAINRTNNIESVAIPRQRSSKNKKPHEHTQSQVRFSIPDPNEISQDSPLKIVFPKSGNETERRMSTSSLLMNSHGHLVDMHSKILVDVPKEVWKFHHNRRKKCESRHRKTRSDVRSNTSSSGKEPNHSRSKSLQSIIVDTMNTYRATEVETSINENTSNISQVSPLNLSFDRPPPLTPEKNLYLTPESPLNRYHLPVPLEISLPPYLSPQNKDKKRSSLVYDGDGYSQFQEGNTSSSTESSLEQPSSSYSDEDDSIPYAHHDVSFELNNADADKLLGIDENANVNLKIQRRNLKNPQHIKSKTDRECEEKNTEKNVSLKILSTPNKLIDIPDLEHMKSPPSTGLNGTLKFFQQFEPSEEPTSPTRQVNPESLDKLDMSFKFPSSTTNNNVDKVHENRNSGDTNNEDFLKVDTSPVNQSFESRRQMLIDLQKSPTNNNPRIHKHRRSRSVHNIDDISLNFEATSTPPAPTSAPSIPVEHSNPCTSIEIPKRSPLRFTSSPKTSDIPPEAQSPKNGSFLQEISVPSIQIIPDESISHTREPSPSLIECPEDENEAFSTEVADHSIAIISETKSVPSIEPFKPLSSFNSFGQEIQNKEPTPLNQTPTDLIGKQRNCVNPHSIPFSVLSSNSQSSQSGSSKSSYNSEFSSNTAITDTTSQPSVTINRSTLEHNFIEEKRSIKNLGHGPPSQKNNYSFPRNKNTPSNRHDLDFNTIYEKRDGKMVEVILLDEDEDVGLKNNDISRTRVCHAQKAKNEQQKKRLSHCNEILGMCDKTADDAKRIIYQLVNEKHKFSEKGQQTKPKKSRVLPPLPFPLYDEKGNSLIPNKYQSSIHNDIPSHRKLK DFD2AB3684EBC1D2 nis1_yeast Protein NIS1 YNL078W N2337 NIS1 JIP1 Neck protein interacting with septins protein 1 Jumonji domain-interacting protein 1 protein protein yeast Saccharomyces cerevisiae Baker's yeast METYETSIGTQSYPPTLFPPPLGTGGFTTSGYIHALVDSTSNSNSNSNTNSNTNSNTNSNSDTKIPIVQISDDSHITHDSFKPYMEYHDASHLRNRNISKADQVESTEVMEQFTQWSNYKMRSRSPTINAKPIRHTSQRRTDFTSKNELSKFSKNHNFIFHKGFLKRQHSIRREDRQAKVRSRFRSKKELTSVLNYIELEQMDIANVLASQPVNLHAIRNLTSRDPAVTPIPFLRSQMYATSSRPPYLRNRSISRKLPKSQPGSLPTTMPATATKTIKQNSTTPTTRSVYNKNVGRSNTSPSVLYHPKRRGKLNTKSHARKEQLLLELWREYLMLVITQRTQLRLTLLCSPGSASNESSVCSSNASDLDMSLLSTPSSLFQMAGETKSNPIIIPDSQDDSILSSDPF 925C7B6063BCE4F1 rga1-ent1-1 3142498 N/A 3142520 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3142521 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false Region 1-151 Region 1-151 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false ent2-rga1-1 3142499 N/A 3142520 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3142522 unspecified role unspecified role bait bait Region 1-149 Region 1-149 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false ent1-rga1-1 3142500 N/A 3142520 unspecified role unspecified role prey prey Region 77-1007 Region 77-1007 sufficient to bind sufficient binding region sufficient to bind full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3142521 unspecified role unspecified role bait bait Region 1-151 Region 1-151 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false ent1-rga1-2 3142501 N/A 3142520 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3142521 unspecified role unspecified role bait bait Region 1-151 Region 1-151 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false rga1-epn1-1 3142502 N/A 3142523 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false Region 1-168 Region 1-168 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3142520 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli direct interaction direct interaction false false false ent2-bem3-1 3142503 N/A 3142524 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3142522 unspecified role unspecified role bait bait Region 1-149 Region 1-149 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false rga1-ent2-1 3142504 N/A 3142520 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli N/A 3142522 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false Region 1-149 Region 1-149 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false ent1-rga2-1 3142505 N/A 3142525 unspecified role unspecified role prey prey Region 414-835 Region 414-835 sufficient to bind sufficient binding region sufficient to bind full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3142521 unspecified role unspecified role bait bait Region 1-151 Region 1-151 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false ent1-bem3-1 3142506 N/A 3142524 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3142521 unspecified role unspecified role bait bait Region 1-151 Region 1-151 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false rga2-ent1-1 3142507 N/A 3142521 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false Region 1-151 Region 1-151 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3142525 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false Region 604-786 Region 604-786 sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli direct interaction direct interaction false false false rga2-epn1-1 3142508 N/A 3142523 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false Region 1-168 Region 1-168 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3142525 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli direct interaction direct interaction false false false epn1-rga2-1 3142509 N/A 3142523 unspecified role unspecified role bait bait Region 1-168 Region 1-168 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3142525 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false ent1-fir1-1 3142510 N/A 3142526 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3142521 unspecified role unspecified role bait bait Region 1-151 Region 1-151 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false ent1-rga2-2 3142511 N/A 3142525 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3142521 unspecified role unspecified role bait bait Q12518:p.Thr104Asp T104D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false Q12518:p.[Tyr100Arg;Thr104Asp] Y100R/T104D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false Region 1-151 Region 1-151 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false rga2-ent1-2 3142512 N/A 3142521 unspecified role unspecified role prey prey Q12518:p.Tyr100Arg Y100R mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain false His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false Region 1-151 Region 1-151 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3142525 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli direct interaction direct interaction false false false epn1-rga1-1 3142513 N/A 3142523 unspecified role unspecified role bait bait Region 1-168 Region 1-168 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3142520 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false rga2-ent2-1 3142514 N/A 3142522 unspecified role unspecified role prey prey His-tag His-tag his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false Region 1-149 Region 1-149 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3142525 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli direct interaction direct interaction false false false ent1-rga2-3 3142515 N/A 3142521 unspecified role unspecified role unspecified role unspecified role Region 1-151 Region 1-151 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false ecolx Escherichia coli N/A 3142525 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction false false false ent1-nis1-1 3142516 N/A 3142527 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3142521 unspecified role unspecified role bait bait Region 1-151 Region 1-151 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false ent2-rga2-1 3142517 N/A 3142522 unspecified role unspecified role bait bait Region 1-149 Region 1-149 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3142525 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false ent1-bem3-2 3142518 N/A 3142524 unspecified role unspecified role prey prey Region 334-548 Region 334-548 sufficient to bind sufficient binding region sufficient to bind full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3142521 unspecified role unspecified role bait bait Region 1-151 Region 1-151 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast physical association physical association false false false rga2-ent1-3 3142519 N/A 3142521 unspecified role unspecified role prey prey yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast N/A 3142525 unspecified role unspecified role bait bait GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false ecolx Escherichia coli physical association physical association false false false