DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ huang-2005-3 in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Huang CC., Stricher F., Martin L., Decker JM., Majeed S., Barthe P., Hendrickson WA., Robinson J., Roumestand C., Sodroski J., Wyatt R., Shaw GM., Vita C., Kwong PD. DIP original experiment: DIP-132762X Structure (London, England : 1993) 2005 IMEx Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth. Huang CC., Stricher F., Martin L., Decker JM., Majeed S., Barthe P., Hendrickson WA., Robinson J., Roumestand C., Sodroski J., Wyatt R., Shaw GM., Vita C., Kwong PD. Only protein-protein interactions imex curation huang-2005-4 in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Huang CC., Stricher F., Martin L., Decker JM., Majeed S., Barthe P., Hendrickson WA., Robinson J., Roumestand C., Sodroski J., Wyatt R., Shaw GM., Vita C., Kwong PD. DIP original experiment: DIP-132763X Structure (London, England : 1993) 2005 IMEx Scorpion-toxin mimics of CD4 in complex with human immunodeficiency virus gp120 crystal structures, molecular mimicry, and neutralization breadth. Huang CC., Stricher F., Martin L., Decker JM., Majeed S., Barthe P., Hendrickson WA., Robinson J., Roumestand C., Sodroski J., Wyatt R., Shaw GM., Vita C., Kwong PD. Only protein-protein interactions imex curation cd4m33/f23 Scorpion-toxin mimic of CD4 peptide peptide polypeptide oligopeptide oligopeptide polypeptide chemical synthesis Chemical synthesis (Chemical synthesis) NLHFCQLRCKSLGLLGKCAGSFCACV env_hv1y2 Envelope glycoprotein gp160 env Env polyprotein protein protein hv1y2 Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1) HIV-1 MRATEIRKNYQHLWKGGTLLLGMLMICSAAEQLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVKLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDLRNATNTTSSSWETMEKGEIKNCSFNITTSIRDKVQKEYALFYNLDVVPIDNASYRLISCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEIVIRSENFTNNAKTIIVQLNESVVINCTRPNNNTRKSINIGPGRALYTTGEIIGDIRQAHCNLSKTQWENTLEQIAIKLKEQFGNNKTIIFNPSSGGDPEIVTHSFNCGGEFFYCNSTQLFTWNDTRKLNNTGRNITLPCRIKQIINMWQEVGKAMYAPPIRGQIRCSSNITGLLLTRDGGKDTNGTEIFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGLGALFLGFLGAAGSTMGAASITLTVQARQLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTTVPWNTSWSNKSLNEIWDNMTWMKWEREIDNYTHIIYSLIEQSQNQQEKNEQELLALDKWASLWNWFDITKWLWYIKIFIMIVGGLIGLRIVFVVLSIVNRVRQGYSPLSFQTHLPAQRGPDRPDGIEEEGGERDRDRSGPLVDGFLAIIWVDLRSLCLFSYHRLRDLLLIVTRIVELLGRRGWGVLKYWWNLLQYWIQELKNSAVSLLNATAIAVAEGTDRVIEILQRAFRAVLHIPVRIRQGLERALL cd4m33/f23-env-1 3137785 N/A 3137787 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3137788 unspecified role unspecified role unspecified role unspecified role gp120 core domain Region 82-479 polyprotein frag polyprotein fragment polyprotein frag certain certain sequence position certain certain certain sequence position certain false drome Drosophila melanogaster (Fruit fly) Fruit fly direct interaction direct interaction false false false cd4m33/f23-env-2 3137786 N/A 3137787 unspecified role unspecified role unspecified role unspecified role in vitro In vitro N/A 3137788 unspecified role unspecified role unspecified role unspecified role gp120 core domain Region 82-479 polyprotein frag polyprotein fragment polyprotein frag certain certain sequence position certain certain certain sequence position certain false drome Drosophila melanogaster (Fruit fly) Fruit fly direct interaction direct interaction false false false