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        <source releaseDate="2018-03-27+01:00">
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                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
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            <attributeList>
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                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
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                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
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            <experimentDescription id="3315802">
                <names>
                    <shortLabel>reiken-2003-1</shortLabel>
                </names>
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                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human-293</shortLabel>
                            <fullName>Homo sapiens transformed primary embryonal kidney cells</fullName>
                            <alias typeAc="MI:1041" type="synonym">Human</alias>
                        </names>
                        <cellType>
                            <names>
                                <shortLabel>293</shortLabel>
                                <fullName>Transformed human primary embryonal kidney cells.</fullName>
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                                <primaryRef db="mint" dbAc="MI:0471" id="MINT-1782570" refType="identity" refTypeAc="MI:0356"/>
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                            <attributeList>
                                <attribute name="comment" nameAc="MI:0612">The Cell type named 293 is synonymous with HEK-293.</attribute>
                            </attributeList>
                        </cellType>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
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                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
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                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
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                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Reiken S., Lacampagne A., Zhou H., Kherani A., Lehnart SE., Ward C., Huang F., Gaburjakova M., Gaburjakova J., Rosemblit N., Warren MS., He KL., Yi GH., Wang J., Burkhoff D., Vassort G., Marks AR.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">arm42@columbia.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">The Journal of cell biology</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2003</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="3315803">
                <names>
                    <shortLabel>reiken-2003-2</shortLabel>
                </names>
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                <hostOrganismList>
                    <hostOrganism ncbiTaxId="1016">
                        <names>
                            <shortLabel>rat-skeletal_muscle</shortLabel>
                            <fullName>rat skeletal muscle</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>skeletal_muscle</shortLabel>
                                <fullName>Skeletal muscle</fullName>
                            </names>
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                                <primaryRef db="brenda" dbAc="MI:0864" id="BTO:0001103" refType="identity" refTypeAc="MI:0356"/>
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                    </hostOrganism>
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                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
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                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
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                    <attribute name="author-list" nameAc="MI:0636">Reiken S., Lacampagne A., Zhou H., Kherani A., Lehnart SE., Ward C., Huang F., Gaburjakova M., Gaburjakova J., Rosemblit N., Warren MS., He KL., Yi GH., Wang J., Burkhoff D., Vassort G., Marks AR.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">arm42@columbia.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">The Journal of cell biology</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2003</attribute>
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                    <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
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            <interactor id="3315804">
                <names>
                    <shortLabel>fkb1a_human</shortLabel>
                    <fullName>Peptidyl-prolyl cis-trans isomerase FKBP1A</fullName>
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                    <alias typeAc="MI:0302" type="gene name synonym">FKBP1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FKBP12</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FK506-binding protein 1A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Rotamase</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Immunophilin FKBP12</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">12 kDa FK506-binding protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Calstabin-1</alias>
                </names>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3MDY" version="SP_182"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032515" secondary="negative regulation of phosphoprotein phosphatase activity" version="SP_182"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1FKF" version="SP_182"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ODP" version="SP_182"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032925" secondary="regulation of activin receptor signaling pathway" version="SP_182"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2DG4" version="SP_182"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9679191" version="SP_182"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6VCU" version="SP_182"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005160" secondary="transforming growth factor beta receptor binding" version="SP_182"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048185" secondary="activin binding" version="SP_182"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042026" secondary="protein refolding" version="SP_182"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2FAP" version="SP_182"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5I7Q" version="SP_182"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE</sequence>
            </interactor>
            <interactor id="3315805">
                <names>
                    <shortLabel>ryr1_rabit</shortLabel>
                    <fullName>Ryanodine receptor 1</fullName>
                    <alias typeAc="MI:0301" type="gene name">RYR1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Skeletal muscle calcium release channel</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Skeletal muscle ryanodine receptor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Skeletal muscle-type ryanodine receptor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Type 1 ryanodine receptor</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P11716" version="SP_120" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I0Y" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAX" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013333" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T9R" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I1E" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014821" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I8M" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005509" secondary="calcium ion binding" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4UWE" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071277" secondary="cellular response to calcium ion" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4P9J" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB0" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051289" secondary="protein homotetramerization" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I2S" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAV" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4UWA" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FG3" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016529" secondary="sarcoplasmic reticulum" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5GL1" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T9N" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAM" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990425" secondary="ryanodine receptor complex" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005219" secondary="ryanodine-sensitive calcium-release channel activity" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097718" secondary="disordered domain specific binding" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5GKY" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043588" secondary="skin development" version="SP_185"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-41872N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071313" secondary="cellular response to caffeine" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3HSM" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ETU" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035761" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB3" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015278" secondary="calcium-release channel activity" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I3N" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAT" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5J8V" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005821" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011992" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005245" secondary="voltage-gated calcium channel activity" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044325" secondary="transmembrane transporter binding" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5C30" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008144" secondary="drug binding" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033215" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005516" secondary="calmodulin binding" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005262" secondary="calcium channel activity" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016093" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035910" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001870" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014808" secondary="release of sequestered calcium ion into cytosol by sarcoplasmic reticulum" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAP" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB1" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAY" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6WOT" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009460" version="SP_185"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6477441" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3ILA" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003032" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006936" secondary="muscle contraction" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I6I" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T9S" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5GL0" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAN" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000699" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043931" secondary="ossification involved in bone maturation" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I37" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003877" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2BCX" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I96" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAW" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7CF9" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048741" secondary="skeletal muscle fiber development" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TA3" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAL" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013662" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5GKZ" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014802" secondary="terminal cisterna" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ERT" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003151" secondary="outflow tract morphogenesis" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAU" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051209" secondary="release of sequestered calcium ion into cytosol" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ETT" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T9M" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013320" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4I7I" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T9V" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6FOO" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ESU" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031301" secondary="integral component of organelle membrane" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035762" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033017" secondary="sarcoplasmic reticulum membrane" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5T15" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAS" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB4" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6M2W" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070588" secondary="calcium ion transmembrane transport" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAZ" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035381" secondary="ATP-gated ion channel activity" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036300" version="SP_185"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015643" secondary="toxic substance binding" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035764" version="SP_185"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR043136" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2XOA" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3J8H" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3RQR" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TAQ" version="SP_185"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5TB2" version="SP_185"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001095188.1"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9986">
                    <names>
                        <shortLabel>rabit</shortLabel>
                        <fullName>Oryctolagus cuniculus (Rabbit)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Rabbit</alias>
                    </names>
                </organism>
                <sequence>MGDGGEGEDEVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFTLEQSLSVRALQEMLANTVEAGVESSQGGGHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPICSCCEEGYVTGGHVLRLFHGHMDECLTISAADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLALTEDQGLVVVDACKAHTKATSFCFRVSKEKLDTAPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLGVLKKKAILHQEGHMDDALFLTRCQQEESQAARMIHSTAGLYNQFIKGLDSFSGKPRGSGPPAGPALPIEAVILSLQDLIGYFEPPSEELQHEEKQSKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEYAGEEAAESWKEIVNLLYELLASLIRGNRANCALFSTNLDWVVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQYGKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLDGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLRLEPIKEYRREGPRGPHLVGPSRCLSHTDFVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVNFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLPKTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSQVENQSRWDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSEPFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPPEHPHYEVARMDGTVDTPPCLRLAHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTAGATPLAPPGLQPPAEDEARAAEPDPDYENLRRSAGGWGEAEGGKEGTAKEGTPGGTPQPGVEAQPVRAENEKDATTEKNKKRGFLFKAKKAAMMTQPPATPALPRLPHDVVPADNRDDPEIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVETRRAGERLGWAVQCQDPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPGRKGGNARRHGLPGVGVTTSLRPPHHFSPPCFVAALPAAGVAEAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVFTEEEEEEEEEEEEEEEEEEDEEEKEEDEEEEEKEDAEKEEEEAPEGEKEDLEEGLLQMKLPESVKLQMCNLLEYFCDQELQHRVESLAAFAERYVDKLQANQRSRYALLMRAFTMSAAETARRTREFRSPPQEQINMLLHFKDEADEEDCPLPEDIRQDLQDFHQDLLAHCGIQLEGEEEEPEEETSLSSRLRSLLETVRLVKKKEEKPEEELPAEEKKPQSLQELVSHMVVRWAQEDYVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGETKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPARDGPGVRRDRRREHFGEEPPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRMAMPCLCAIAGALPPDYVDASYSSKAEKKATVDAEGNFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENVDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIEKAREGEEERTEKKKTRKISQTAQTYDPREGYNPQPPDLSGVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRGLKDMELDTSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQARTQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTKNTYVEKLRPALGECLARLAAAMPVAFLEPQLNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLDRLMADIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEATWMKRLAVFAQPIVSRARPELLHSHFIPTIGRLRKRAGKVVAEEEQLRLEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRAHWLTEPNANAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADSKSKMAKAGDAQSGGSDQERTKKKRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLIMLAKTRYALKDTDEEVREFLQNNLHLQGKVEGSPSLRWQMALYRGLPGREEDADDPEKIVRRVQEVSAVLYHLEQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCHLEEGGENGEAEEEEVEVSFEEKEMEKQRLLYQQSRLHTRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINFEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISEPEGEPEADEDEGMGEAAAEGAEEGAAGAEGAAGTVAAGATARLAAAAARALRGLSYRSLRRRVRRLRRLTAREAATALAALLWAVVARAGAAGAGAAAGALRLLWGSLFGGGLVEGAKKVTVTELLAGMPDPTSDEVHGEQPAGPGGDADGAGEGEGEGDAAEGDGDEEVAGHEAGPGGAEGVVAVADGGPFRPEGAGGLGDMGDTTPAEPPTPEGSPILKRKLGVDGEEEELVPEPEPEPEPEPEKADEENGEKEEVPEAPPEPPKKAPPSPPAKKEEAGGAGMEFWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPGEDDMEGSAAGDLAGAGSGGGSGWGSGAGEEAEGDEDENMVYYFLEESTGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPGDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEITAHNERKPDPPPGLLTWLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS</sequence>
            </interactor>
            <interactor id="3315806">
                <names>
                    <shortLabel>pde4d_rat</shortLabel>
                    <fullName>cAMP-specific 3',5'-cyclic phosphodiesterase 4D</fullName>
                    <alias typeAc="MI:0301" type="gene name">Pde4d</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">DPDE3</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P14270" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001934" secondary="positive regulation of protein phosphorylation" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008277" secondary="regulation of G protein-coupled receptor signaling pathway" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043951" secondary="negative regulation of cAMP-mediated signaling" version="SP_176"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_008758943.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" secondary="Golgi apparatus" version="SP_176"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002073"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003607"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004115" secondary="3',5'-cyclic-AMP phosphodiesterase activity" version="SP_176"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001106805.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6TRI0" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036971"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" secondary="perinuclear region of cytoplasm" version="SP_176"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8CG06" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034622" secondary="cellular protein-containing complex assembly" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007568" secondary="aging" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030552" secondary="cAMP binding" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030016" secondary="myofibril" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014911" secondary="positive regulation of smooth muscle cell migration" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032729" secondary="positive regulation of interferon-gamma production" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006198" secondary="cAMP catabolic process" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0086024" secondary="adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate" version="SP_176"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8333209" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016324" secondary="apical plasma membrane" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035264" secondary="multicellular organism growth" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007613" secondary="memory" version="SP_176"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_008758944.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023088"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002027" secondary="regulation of heart rate" version="SP_176"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="F1M1H7" version="SP_120" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-180024"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032754" secondary="positive regulation of interleukin-5 production" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048661" secondary="positive regulation of smooth muscle cell proliferation" version="SP_176"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-418555"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031698" secondary="beta-2 adrenergic receptor binding" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901898" secondary="negative regulation of relaxation of cardiac muscle" version="SP_176"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001106799.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0022409" secondary="positive regulation of cell-cell adhesion" version="SP_176"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="MINT-8432590" refType="intact-secondary"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004114" secondary="3',5'-cyclic-nucleotide phosphodiesterase activity" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050900" secondary="leukocyte migration" version="SP_176"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001106803.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030593" secondary="neutrophil chemotaxis" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060314" secondary="regulation of ryanodine-sensitive calcium-release channel activity" version="SP_176"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_058728.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR040844"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044325" secondary="transmembrane transporter binding" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050852" secondary="T cell receptor signaling pathway" version="SP_176"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001106800.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_176"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_008758945.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006939" secondary="smooth muscle contraction" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034705" secondary="potassium channel complex" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901363" secondary="heterocyclic compound binding" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051117" secondary="ATPase binding" version="SP_176"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O35470" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032743" secondary="positive regulation of interleukin-2 production" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071320" secondary="cellular response to cAMP" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" secondary="metal ion binding" version="SP_176"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097110" secondary="scaffold protein binding" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033137" secondary="negative regulation of peptidyl-serine phosphorylation" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045822" secondary="negative regulation of heart contraction" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0086004" secondary="regulation of cardiac muscle cell contraction" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005813" secondary="centrosome" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" secondary="signal transduction" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005891" secondary="voltage-gated calcium channel complex" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071222" secondary="cellular response to lipopolysaccharide" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_176"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A1EC59" version="SP_120" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010469" secondary="regulation of signaling receptor activity" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071875" secondary="adrenergic receptor signaling pathway" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034704" secondary="calcium channel complex" version="SP_176"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A1E347" version="SP_120" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004112" secondary="cyclic-nucleotide phosphodiesterase activity" version="SP_176"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8CG04" version="SP_116" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010880" secondary="regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030324" secondary="lung development" version="SP_176"/>
                    <secondaryRef db="rgd" dbAc="MI:0483" id="3281"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061028" secondary="establishment of endothelial barrier" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043949" secondary="regulation of cAMP-mediated signaling" version="SP_176"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071872" secondary="cellular response to epinephrine stimulus" version="SP_176"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10116">
                    <names>
                        <shortLabel>rat</shortLabel>
                        <fullName>Rattus norvegicus (Rat)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Rat</alias>
                    </names>
                </organism>
                <sequence>MEAEGSSVPARAGSHEGSDSSGGAALKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPPPPPSPQPQLQPPPPPPLPPPPPPPGATRGRYASSGASRVRHRGYSDTERYLYCRAMDRTSYAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQISGVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQEDGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVEEEAVAEEESQPQTGVADDCCPDT</sequence>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interactor>
            <interactor id="3315807">
                <names>
                    <shortLabel>akap6_rat</shortLabel>
                    <fullName>A-kinase anchor protein 6</fullName>
                    <alias typeAc="MI:0301" type="gene name">Akap6</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Protein kinase A-anchoring protein 6</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">mAKAP</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9WVC7" version="SP_43" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034629" secondary="cellular protein-containing complex localization" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901897" secondary="regulation of relaxation of cardiac muscle" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016529" secondary="sarcoplasmic reticulum" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007194" secondary="negative regulation of adenylate cyclase activity" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061051" secondary="positive regulation of cell growth involved in cardiac muscle cell development" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071872" secondary="cellular response to epinephrine stimulus" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044325" secondary="transmembrane transporter binding" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010738" secondary="regulation of protein kinase A signaling" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005635" secondary="nuclear envelope" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001934" secondary="positive regulation of protein phosphorylation" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005901" secondary="caveola" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014704" secondary="intercalated disc" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030315" secondary="T-tubule" version="SP_119"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="MINT-4998500" refType="intact-secondary"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031965" secondary="nuclear membrane" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034704" secondary="calcium channel complex" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070886" secondary="positive regulation of calcineurin-NFAT signaling cascade" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014701" secondary="junctional sarcoplasmic reticulum membrane" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043495" secondary="protein-membrane adaptor activity" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060316" secondary="positive regulation of ryanodine-sensitive calcium-release channel activity" version="SP_119"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002017"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008179" secondary="adenylate cyclase binding" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030307" secondary="positive regulation of cell growth" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010880" secondary="regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051281" secondary="positive regulation of release of sequestered calcium ion into cytosol" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045727" secondary="positive regulation of translation" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060306" secondary="regulation of membrane repolarization" version="SP_119"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7559840" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071320" secondary="cellular response to cAMP" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051721" secondary="protein phosphatase 2A binding" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0086004" secondary="regulation of cardiac muscle cell contraction" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034237" secondary="protein kinase A regulatory subunit binding" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048471" secondary="perinuclear region of cytoplasm" version="SP_119"/>
                    <secondaryRef db="rgd" dbAc="MI:0483" id="69412"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051018" secondary="protein kinase A binding" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902261" secondary="positive regulation of delayed rectifier potassium channel activity" version="SP_119"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018159"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000481" secondary="positive regulation of cAMP-dependent protein kinase activity" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042383" secondary="sarcolemma" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071345" secondary="cellular response to cytokine stimulus" version="SP_119"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901381" secondary="positive regulation of potassium ion transmembrane transport" version="SP_119"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_072140.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060090" secondary="molecular adaptor activity" version="SP_119"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10116">
                    <names>
                        <shortLabel>rat</shortLabel>
                        <fullName>Rattus norvegicus (Rat)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Rat</alias>
                    </names>
                </organism>
                <sequence>MLTMSVTLSPLRSQGPDPMATDASPMAINMTPTVEQEEGEGEEAVKAIDAEQQYGKPPPLHTAADWKIVLHLPEIETWLRMTSERVRDLTYSVQQDADSKHVDVHLVQLKDICEDISDHVEQIHALLETEFSLKLLSYSVNVIVDIHAVQLLWHQLRVSVLVLRERILQGLQDANGNYTRQTDILQAFSEETTEGRLDSLTEVDDSGQLTIKCSQDYLSLDCGITAFELSDYSPSEDLLGGLGDMTTSQAKTKSFDSWSYSEMEKEFPELIRSVGLLTVATEPVPSSCGEANEDSSQASLSDDHKGEHGEDGAPVPGQQLDSTVGMSSLDGTLANAAEHPSETAKQDSTSSPQLGAKKTQPGPCEITTPKRSIRDCFNYNEDSPTQPTLPKRGLFLKETQKNERKGSDRKGQVVDLKPELSRSTPSLVDPPDRSKLCLVLQSSYPSSPSAASQSYECLHKVGLGNLENIVRSHIKEISSSLGRLTDCHKEKLRLKKPHKTLAEVSLCRIPKQGGGSGKRSESTGSSAGPSMVSPGAPKATMRPETDSASTASGGLCHQRNRSGQLPVQSKASSSPPCSHSSESSLGSDSIKSPVPLLSKNKSQKSSPPAPCHATQNGQVVEAWYGSDEYLALPSHLKQTEVLALKLESLTKLLPQKPRGETIQDIDDWELSEMNSDSEIYPTYHIKKKHTRLGTVSPSSSSDIASSLGESIESGPLSDILSDEDLCLPLSSVKKFTDEKSERPSSSEKNESHSATRSALIQKLMHDIQHQENYEAIWERIEGFVNKLDEFIQWLNEAMETTENWTPPKAETDSLRLYLETHLSFKLNVDSHCALKEAVEEEGHQLLELVVSHKAGLKDTLRMIASQWKELQRQIKRQHSWILRALDTIKAEILATDVSVEDEEGTGSPKAEVQLCHLETQRDAVEQMSLKLYSEQYTSGSKRKEEFANMSKAHAEGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKSELLSKVEALKKGGLSLPDDILEKVDSINEKWELLGKTLREKIQDTIAGHSGSGPRDLLSPESGSLVRQLEVRIKELKRWLRDTELFIFNSCLRQEKEGTSAEKQLQYFKSLCREIKQRRRGVASILRLCQHLLDDRDTCNLNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSEDALEWDETDISNKLISVHEESNDLDQDPEPMLPAVKLEETHHKDSGYEEEAGDCGGSPYTSNITAPSSPHIYQVYSLHNVELHEDSHTPFLKSSPKFTGTTQPTVLTKSLSKDSSFSSTKSLPDLLGGSGLVRPYSCHSGDLSQNSGSESGIVSEGDNEMPTNSDMSLFSMVDGSPSNPETEHPDPQMGDAANVLEQKFKDNGESIKLSSVSRASVSPVGCVNGKAGDLNSVTKHTADCLGEELQGKHDVFTFYDYSYLQGSKLKLPMIMKQPQSEKAHVEDPLLGGFYFDKKSCKAKHQASESQPDAPPHERILASAPHEMGRSAYKSSDIEKTFTGIQSARQLSLLSRSSSVESLSPGGDLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDMTLQSSSQKMPFAGQMSLDVASSINEDSPASLTELSSSDELSLCSEDIVLHKNKIPESNASFRKRLNRSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCLKDEDDDSSIATDDEIYEESNLMSGLDYIKNELQTWIRPKLSLTREKKRSGVTDEIKVNKDGGGNEKANPSDTLDIEALLNGSIRCLSENNGNGKTPPRTHGSGTKGENKKSTYDVSKDPHVADMENGNIESTPEREREKPQGLPEVSENLASNVKTISESELSEYEAVMDGSEDSSVARKEFCPPNDRHPPQMGPKLQHPENQSGDCKPVQNPCPGLLSEAGVGSRQDSNGLKSLPNDAPSGARKPAGCCLLEQNETEESASISSNASCCNCKPDVFHQKDDEDCSVHDFVKEIIDMASTALKSKSQPESEVAAPTSLTQIKEKVLEHSHRPIHLRKGDFYSYLSLSSHDSDCGEVTNYIDEKSSTPLPPDAVDSGLDDKEDMDCFFEACVEDEPVNEEAGLPGALPNESAIEDGAEQKSEQKTASSPVLSDKTDLVPLSGLSPQKGADDAKEGDDVSHTSQGCAESTEPTTPSGKANAEGRSRMQGVSATPEENAASAKPKIQAFSLNAKQPKGKVAMRYPSPQTLTCKEKLVNFHEDRHSNMHR</sequence>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="function" nameAc="MI:0613">Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes</attribute>
                </attributeList>
            </interactor>
            <interactor id="3315808">
                <names>
                    <shortLabel>ryr1_rat</shortLabel>
                    <fullName>Ryanodine receptor 1</fullName>
                    <alias typeAc="MI:0301" type="gene name">Ryr1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Skeletal muscle calcium release channel</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Skeletal muscle ryanodine receptor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Skeletal muscle-type ryanodine receptor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Type 1 ryanodine receptor</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="F1LMY4" version="SP_23" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR043136"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990425" secondary="ryanodine receptor complex" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005790" secondary="smooth endoplasmic reticulum" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" secondary="response to hypoxia" version="SP_80"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9R272" version="SP_23" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001870"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013662"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036300"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="MINT-195292" refType="intact-secondary"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030018" secondary="Z disc" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003151" secondary="outflow tract morphogenesis" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005516" secondary="calmodulin binding" version="SP_80"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-5578775"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014808" secondary="release of sequestered calcium ion into cytosol by sarcoplasmic reticulum" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" secondary="protein-containing complex" version="SP_80"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035910"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005219" secondary="ryanodine-sensitive calcium-release channel activity" version="SP_80"/>
                    <secondaryRef db="rgd" dbAc="MI:0483" id="1586637"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030314" secondary="junctional membrane complex" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006816" secondary="calcium ion transport" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005938" secondary="cell cortex" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032355" secondary="response to estradiol" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071277" secondary="cellular response to calcium ion" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042383" secondary="sarcolemma" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005509" secondary="calcium ion binding" version="SP_80"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009460"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048741" secondary="skeletal muscle fiber development" version="SP_80"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9R1G1" version="SP_23" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033017" secondary="sarcoplasmic reticulum membrane" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014802" secondary="terminal cisterna" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051289" secondary="protein homotetramerization" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051209" secondary="release of sequestered calcium ion into cytosol" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031234" secondary="extrinsic component of cytoplasmic side of plasma membrane" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034704" secondary="calcium channel complex" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030315" secondary="T-tubule" version="SP_80"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016093"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000699"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035764"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003032"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043931" secondary="ossification involved in bone maturation" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031000" secondary="response to caffeine" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016529" secondary="sarcoplasmic reticulum" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030659" secondary="cytoplasmic vesicle membrane" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043588" secondary="skin development" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051480" secondary="regulation of cytosolic calcium ion concentration" version="SP_80"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-2672351"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031674" secondary="I band" version="SP_80"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035762"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_80"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011992"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071313" secondary="cellular response to caffeine" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_80"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033215"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070296" secondary="sarcoplasmic reticulum calcium ion transport" version="SP_80"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035761"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013320"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031301" secondary="integral component of organelle membrane" version="SP_80"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014821"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7811804" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071318" secondary="cellular response to ATP" version="SP_80"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005821"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003877"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002020" secondary="protease binding" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006936" secondary="muscle contraction" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005262" secondary="calcium channel activity" version="SP_80"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005245" secondary="voltage-gated calcium channel activity" version="SP_80"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013333"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O35208" version="SP_23" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048763" secondary="calcium-induced calcium release activity" version="SP_80"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10116">
                    <names>
                        <shortLabel>rat</shortLabel>
                        <fullName>Rattus norvegicus (Rat)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Rat</alias>
                    </names>
                </organism>
                <sequence>MGDGGGEGEDEVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFILEQSLSVRALQEMLANTVEAGVESSQGGGHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPICSCCEEGFVTGGHVLRLFHGHMDECLTISPSDSDDQRRLVYYEGGPVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLALTEDQGLVVVDASKAHTKATSFCFRISKEKLDVAPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLGVLKKKAMLHQEGHMDDALSLTRCQQEESQAARMIYSTAGLYNQFIKGLDSFSGKPRGSGPPAGSALPIEGVILSLQDLIGYFEPPSEELQHEEKQTKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEFAGEEAAESWKEIVNLLYELLASLIRGNRTNCALFSTNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQYGKWYFEVMVDEVAPFLTAQATHLRVGWALSEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTSPGQHLLGPEDVVSCCLDLSVPSISFRINGCPVQGVFESFNLDGLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLHLQPIKEYRREGPRGPHLVGPSRCLSHLDFVPCPVDTIQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVDFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLPKTYMMNNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSQVDSQSRGDRARIFRAEKSYAVQSGRWYFEFEAVTTGRELGWARPELRPDVELGADDLAYVFNGHRGQRWHLGSEPFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPLEHPHYEVARMDGTVDTPPCLRLTHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTAGATPLASPGLQPPAEDEARAAEPDTDYENLRRSAGGWGEAEAGKDGTAKEGTPGGAAQPGVEAQPARAENEKDATTEKNKKRGFLFKAKKVAMMTQPPSTPALPRLPRDVVPADNRDDPEIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMSFDLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVVQFDLRPGANIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLHVDTRRAGERLGWAVQCQEPLMMMALHIPEENSEPYIHLKRAQLDPRDLRDYRDTKFDSESSDSDQTPQPGCYHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTEETRAITLFPPGRSAEDGPRRHGLPGVGVTTSLRPPHHFSPPCFVVALPAAGAAEAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGVFSDEDVKQILKMIEPEVFTEEEEVEEEEEEEEEDEEEKEEDEEEEAHEKEDEEKEEAEEAAEEEKEELEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAERYVDKLQSNQRGRYGLLMKAFTMSAAETARRTREFRSPPQEQINMLLQFKNGADEEDCPLPEEIREDLVNFHQDLLAHCGIQLEGEEEEPEEESTLGSRLMSLLEKVRLVKKKEEKPEEEPAAEEHKPQSLQELVSHTVVRWAQEDFVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISLSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGESKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEAIRISEDPARDGPGVRRDRRREHFGEEPPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSRRWALALTRYLCAVLPLITKCAPLLRGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRIAMPCLCAIAGALPPDYVDASYSSKTEKKATVDAEGNFDPRPVETLNVIIPEKLDSFINKFAEYAHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTVEKAREGEEEKTEKKKTRKISQTAQTYDPREGYNPQPPDLSVVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGSHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRHGKDMELDTSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQARTQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTRNPYVEKLRPALGECLARLAAAMPVAFLEPELNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLERLMAEIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEASWMKRLAVFAQPIVSRARPELLRSHFIPTIGRLRKRAGKVVAEEEQLRLEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRSAWPRLPPSPSSSFSLPSPSELGRWLMKDHGHQLYEESFTVPLILDNAAFPLARNQSRAIGCAGVVRSGGSDQERTKKKRRGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQDLIVLAKARYALKDTDEEVREFLQNNLNLQGKVEGSPSLRWQMALYRGVPGREEDADDPEKIVRRVQEVSAVLYHLDQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKASWILTEDHSFEDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCHLEEGGENVEEGGEEEEVEVSFEEKEMEKQRLLYQQSRLHNRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCRWPHKTLSQREGQEERVMKVQTSGTLVIINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINCEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILDYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGESEKMELFVSFCEDTIFEMQIAAQISEPEGEPEEDDDEGAEEAEEGAAGPDGSGSAAAAGVWTWLATAAGRTLRGLSYRSLRRRVRRLRRLTAREAATAVAVLLWAMVARAGGAGAGAAAGVLRLLWGSLFGGGLVDSAKKVTVTELLAGMPDPTGDEVHGQQPSGAGSDAEGEGQGEGEGDAAEGVGDEEVAADQAGTGGADRTVAVADGSPFRPEGAGGLGDMGDTTPVEPPTPEGSPILKRKLGVDGEEEEPQPEPEPEPEPEPEKADTENGEKEVPEPPPEPPKKAPPPPPPKKEEAGGAGLEEFWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPGEDDIEGSGAGDMSGAGSGDGSGWGSRASEEVEGDEDENMVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPEDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEITAHNERKPDPPPGLLTWIMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG</sequence>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">fragmentation type: fragment</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interactor>
            <interactor id="3315809">
                <names>
                    <shortLabel>fkb1a_rat</shortLabel>
                    <fullName>Peptidyl-prolyl cis-trans isomerase FKBP1A</fullName>
                    <alias typeAc="MI:0301" type="gene name">Fkbp1a</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Fkbp1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">12 kDa FK506-binding protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FK506-binding protein 1A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Immunophilin FKBP12</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Rotamase</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q62658" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051209" secondary="release of sequestered calcium ion into cytosol" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031312" secondary="extrinsic component of organelle membrane" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033017" secondary="sarcoplasmic reticulum membrane" version="SP_160"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOG00000008822" version="SP_160" refType="gene"/>
                    <secondaryRef db="rgd" dbAc="MI:0483" id="2617"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043231" secondary="intracellular membrane-bounded organelle" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097435" secondary="supramolecular fiber organization" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016529" secondary="sarcoplasmic reticulum" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034713" secondary="type I transforming growth factor beta receptor binding" version="SP_160"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-2025928" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000413" secondary="protein peptidyl-prolyl isomerization" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044325" secondary="transmembrane transporter binding" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042098" secondary="T cell proliferation" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003755" secondary="peptidyl-prolyl cis-trans isomerase activity" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032092" secondary="positive regulation of protein binding" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032515" secondary="negative regulation of phosphoprotein phosphatase activity" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032925" secondary="regulation of activin receptor signaling pathway" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098562" secondary="cytoplasmic side of membrane" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902991" secondary="regulation of amyloid precursor protein catabolic process" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990000" secondary="amyloid fibril formation" version="SP_160"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A0JN04" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010039" secondary="response to iron ion" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005160" secondary="transforming growth factor beta receptor binding" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048185" secondary="activin binding" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007183" secondary="SMAD protein complex assembly" version="SP_160"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-16420790" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019221" secondary="cytokine-mediated signaling pathway" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006936" secondary="muscle contraction" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061077" secondary="chaperone-mediated protein folding" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030512" secondary="negative regulation of transforming growth factor beta receptor signaling pathway" version="SP_160"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOT00000012608" version="SP_160" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060347" secondary="heart trabecula formation" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005528" secondary="FK506 binding" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030018" secondary="Z disc" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003007" secondary="heart morphogenesis" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030544" secondary="Hsp70 protein binding" version="SP_160"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001179" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043679" secondary="axon terminus" version="SP_160"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_037234.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050776" secondary="regulation of immune response" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060314" secondary="regulation of ryanodine-sensitive calcium-release channel activity" version="SP_160"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="P97533" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-2173789" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045202" secondary="synapse" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031000" secondary="response to caffeine" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046332" secondary="SMAD binding" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990425" secondary="ryanodine receptor complex" version="SP_160"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSRNOP00000012608" version="SP_160" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-RNO-166208" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032880" secondary="regulation of protein localization" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0055010" secondary="ventricular cardiac muscle tissue morphogenesis" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031398" secondary="positive regulation of protein ubiquitination" version="SP_160"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_160"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10116">
                    <names>
                        <shortLabel>rat</shortLabel>
                        <fullName>Rattus norvegicus (Rat)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Rat</alias>
                    </names>
                </organism>
                <sequence>MGVQVETISSGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFTLGKQEVIRGWEEGVAQMSVGQRAKLIISPDYAYGATGHPGIIPPHATLVFDVELLKLE</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-26360-1" id="3315810">
                <names>
                    <shortLabel>fkbp1a-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-16420768" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26360-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3315802</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3315811">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16420770" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3315804</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="3315812">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16420769" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3315805</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>over-expressed</shortLabel>
                                    <fullName>over expressed level</fullName>
                                    <alias typeAc="MI:1041" type="synonym">over-expressed</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0506" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537736" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <featureList>
                            <feature id="3315813">
                                <names>
                                    <shortLabel>P11716:p.Ser2843Asp</shortLabel>
                                    <fullName>p.ser2843asp</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-16420772" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>mutation disrupting</shortLabel>
                                        <fullName>mutation disrupting interaction</fullName>
                                        <alias typeAc="MI:1041" type="synonym">mutation disrupting</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0573" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-705401" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <begin position="2843"/>
                                        <endStatus>
                                            <names>
                                                <shortLabel>certain</shortLabel>
                                                <fullName>certain sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">certain</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <end position="2843"/>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F1C</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-26360-3" id="3315814">
                <names>
                    <shortLabel>akap6-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-16420846" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26360-3" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>3315803</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="3315815">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16420850" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3315806</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="3315816">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16420849" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3315807</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="3315817">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16420848" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3315808</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="3315818">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-16420847" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>3315809</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f6b</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
