<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2017-08-31+01:00">
            <names>
                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
                <alias typeAc="MI:1041" type="synonym">IntAct</alias>
                <alias typeAc="MI:1041" type="synonym">intact</alias>
            </names>
            <bibref>
                <xref>
                    <primaryRef db="pubmed" dbAc="MI:0446" id="14681455" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
            </bibref>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0469" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-10" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="19850723" refType="method reference" refTypeAc="MI:0357"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681455" refType="primary-reference" refTypeAc="MI:0358"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="22121220" refType="method reference" refTypeAc="MI:0357"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
                <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
                <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
                <attribute name="url">http://www.ebi.ac.uk/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="2968953">
                <names>
                    <shortLabel>bouchon-2001-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="11602640" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-14036356" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25818" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human-monocyte</shortLabel>
                            <fullName>Human mononuclear cells</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>monocyte</shortLabel>
                                <fullName>Monocyte, mononuclear cell</fullName>
                            </names>
                            <xref>
                                <primaryRef db="mint" dbAc="MI:0471" id="MINT-8286755" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1810080" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="brenda" dbAc="MI:0864" id="BTO:0000876" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </tissue>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Bouchon A., Hernández-Munain C., Cella M., Colonna M.</attribute>
                    <attribute name="exp-modification" nameAc="MI:0627">Pervanadate (phosphatase inhibitor)  stimulation under reducing conditions.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">mcolonna@pathology.wustl.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">The Journal of experimental medicine</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2001</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
            <experimentDescription id="2968954">
                <names>
                    <shortLabel>bouchon-2001-2</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="11602640" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-14036375" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25818" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="9606">
                        <names>
                            <shortLabel>human-mddc</shortLabel>
                            <fullName>Human Monocyte-derived dendritic cell</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>monocyte-derived_dendritic_cell</shortLabel>
                                <fullName>Monocyte-derived dendritic cell (MDDC)</fullName>
                            </names>
                            <xref>
                                <primaryRef db="brenda" dbAc="MI:0864" id="BTO:0002900" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="IA:2386" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6859240" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </tissue>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Bouchon A., Hernández-Munain C., Cella M., Colonna M.</attribute>
                    <attribute name="exp-modification" nameAc="MI:0627">Pervanadate (phosphatase inhibitor)  stimulation under reducing conditions.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">mcolonna@pathology.wustl.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">The Journal of experimental medicine</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2001</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="2968955">
                <names>
                    <shortLabel>tyobp_human</shortLabel>
                    <fullName>TYRO protein tyrosine kinase-binding protein</fullName>
                    <alias typeAc="MI:0301" type="gene name">TYROBP</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">DAP12</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">KARAP</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">DNAX-activation protein 12</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Killer-activating receptor-associated protein</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="O43914" version="SP_71" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0110090" secondary="positive regulation of hippocampal neuron apoptotic process" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035556" secondary="intracellular signal transduction" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030667" secondary="secretory granule membrane" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000010" secondary="positive regulation of protein localization to cell surface" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002274" secondary="myeloid leukocyte activation" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900272" secondary="negative regulation of long-term synaptic potentiation" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901216" secondary="positive regulation of neuron death" version="SP_175"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2L35" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002282" secondary="microglial cell activation involved in immune response" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032731" secondary="positive regulation of interleukin-1 beta production" version="SP_175"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-416700" version="SP_175"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6FGA5" version="SP_71" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032755" secondary="positive regulation of interleukin-6 production" version="SP_175"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2L34" version="SP_175"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2424491" version="SP_175"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6798695" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002222" secondary="stimulatory killer cell immunoglobulin-like receptor signaling pathway" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032760" secondary="positive regulation of tumor necrosis factor production" version="SP_175"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_937758.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030036" secondary="actin cytoskeleton organization" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904151" secondary="positive regulation of microglial cell mediated cytotoxicity" version="SP_175"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-391160" version="SP_175"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000262629" version="SP_175" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002223" secondary="stimulatory C-type lectin receptor signaling pathway" version="SP_175"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UMT3" version="SP_71" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097190" secondary="apoptotic signaling pathway" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2001206" secondary="positive regulation of osteoclast development" version="SP_175"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001166985.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="F5H389" version="SP_111" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WO1" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" secondary="protein homodimerization activity" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032911" secondary="negative regulation of transforming growth factor beta1 production" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005102" secondary="signaling receptor binding" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032693" secondary="negative regulation of interleukin-10 production" version="SP_175"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_003323.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" secondary="metal ion binding" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006968" secondary="cellular defense response" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034241" secondary="positive regulation of macrophage fusion" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050821" secondary="protein stabilization" version="SP_175"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WOL" version="SP_175"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR026200" version="SP_175"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K2X0" version="SP_72" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007165" secondary="signal transduction" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030900" secondary="forebrain development" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032816" secondary="positive regulation of natural killer cell activation" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030316" secondary="osteoclast differentiation" version="SP_175"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2172127" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902685" secondary="positive regulation of receptor localization to synapse" version="SP_175"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000262629" version="SP_175" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032930" secondary="positive regulation of superoxide anion generation" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002283" secondary="neutrophil activation involved in immune response" version="SP_175"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2214794" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030889" secondary="negative regulation of B cell proliferation" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048678" secondary="response to axon injury" version="SP_175"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-198933" version="SP_175"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000011600" version="SP_175" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043277" secondary="apoptotic cell clearance" version="SP_175"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MGGLEPCSRLLLLPLLLAVSGLRPVQAQAQSDCSCSTVSPGVLAGIVMGDLVLTVLIALAVYFLGRLVPRGRGAAEAATRKQRITETESPYQELQGQRSDVYSDLNTQRPYYK</sequence>
            </interactor>
            <interactor id="2968956">
                <names>
                    <shortLabel>trem1_human</shortLabel>
                    <fullName>Triggering receptor expressed on myeloid cells 1</fullName>
                    <alias typeAc="MI:0301" type="gene name">TREM1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Triggering receptor expressed on monocytes 1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NP99" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013106" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035556" secondary="intracellular signal transduction" version="SP_172"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53FL8" version="SP_141" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006959" secondary="humoral immune response" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097110" secondary="scaffold protein binding" version="SP_172"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1SMO" version="SP_172"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001229518.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_061113.1"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000124731" version="SP_172" refType="gene"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-13943454" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038023" secondary="signaling receptor activity" version="SP_172"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR039141" version="SP_172"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013783" version="SP_172"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000244709" version="SP_172" refType="transcript"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000244709" version="SP_172" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045087" secondary="innate immune response" version="SP_172"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-202733" version="SP_172"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4DWG2" version="SP_141" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="K7EJW1" version="SP_141" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001229519.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002250" secondary="adaptive immune response" version="SP_172"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5T2C9" version="SP_141" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" secondary="extracellular region" version="SP_172"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016866445.1"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2172127" version="SP_172"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036179" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_172"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016866446.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1Q8M" version="SP_172"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-198933" version="SP_172"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003599" version="SP_172"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002526" secondary="acute inflammatory response" version="SP_172"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q86YU1" version="SP_141" refType="secondary-ac" refTypeAc="MI:0360"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MRKTRLWGLLWMLFVSELRAATKLTEEKYELKEGQTLDVKCDYTLEKFASSQKAWQIIRDGEMPKTLACTERPSKNSHPVQVGRIILEDYHDHGLLRVRMVNLQVEDSGLYQCVIYQPPKEPHMLFDRIRLVVTKGFSGTPGSNENSTQNVYKIPPTTTKALCPLYTSPRTVTQAPPKSTADVSTPDSEINLTNVTDIIRVPVFNIVILLAGGFLSKSLVFSVLFAVTLRSFVP</sequence>
            </interactor>
            <interactor id="2968957">
                <names>
                    <shortLabel>trem2_human</shortLabel>
                    <fullName>Triggering receptor expressed on myeloid cells 2</fullName>
                    <alias typeAc="MI:0301" type="gene name">TREM2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Triggering receptor expressed on monocytes 2</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NZC2" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008035" secondary="high-density lipoprotein particle binding" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045960" secondary="positive regulation of complement activation, classical pathway" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034186" secondary="apolipoprotein A-I binding" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070374" secondary="positive regulation of ERK1 and ERK2 cascade" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060100" secondary="positive regulation of phagocytosis, engulfment" version="SP_165"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YYE" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070269" secondary="pyroptosis" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010507" secondary="negative regulation of autophagy" version="SP_165"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-198933" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004888" secondary="transmembrane signaling receptor activity" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071813" secondary="lipoprotein particle binding" version="SP_165"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5UD7" version="SP_165"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Y6C" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903980" secondary="positive regulation of microglial cell activation" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001786" secondary="phosphatidylserine binding" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904093" secondary="negative regulation of autophagic cell death" version="SP_165"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Z0H" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905808" secondary="positive regulation of synapse pruning" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043124" secondary="negative regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050731" secondary="positive regulation of peptidyl-tyrosine phosphorylation" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903753" secondary="negative regulation of p38MAPK cascade" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0150076" secondary="neuroinflammatory response" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070345" secondary="negative regulation of fat cell proliferation" version="SP_165"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036179" version="SP_165"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6B8O" version="SP_165"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000095970" version="SP_165" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006910" secondary="phagocytosis, recognition" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904141" secondary="positive regulation of microglial cell migration" version="SP_165"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2424491" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097110" secondary="scaffold protein binding" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900226" secondary="negative regulation of NLRP3 inflammasome complex assembly" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001540" secondary="amyloid-beta binding" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007613" secondary="memory" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098657" secondary="import into cell" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060075" secondary="regulation of resting membrane potential" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061889" secondary="negative regulation of astrocyte activation" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032733" secondary="positive regulation of interleukin-10 production" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019216" secondary="regulation of lipid metabolic process" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032006" secondary="regulation of TOR signaling" version="SP_165"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5ELI" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0055088" secondary="lipid homeostasis" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030316" secondary="osteoclast differentiation" version="SP_165"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000362205" version="SP_165" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048143" secondary="astrocyte activation" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014068" secondary="positive regulation of phosphatidylinositol 3-kinase signaling" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901224" secondary="positive regulation of NIK/NF-kappaB signaling" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2001171" secondary="positive regulation of ATP biosynthetic process" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" secondary="extracellular region" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048678" secondary="response to axon injury" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900223" secondary="positive regulation of amyloid-beta clearance" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904646" secondary="cellular response to amyloid-beta" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071456" secondary="cellular response to hypoxia" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043277" secondary="apoptotic cell clearance" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010822" secondary="positive regulation of mitochondrion organization" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071223" secondary="cellular response to lipoteichoic acid" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050866" secondary="negative regulation of cell activation" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904951" secondary="positive regulation of establishment of protein localization" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905291" secondary="positive regulation of CAMKK-AMPK signaling cascade" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031226" secondary="intrinsic component of plasma membrane" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002282" secondary="microglial cell activation involved in immune response" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010468" secondary="regulation of gene expression" version="SP_165"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-416700" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0120035" secondary="regulation of plasma membrane bounded cell projection organization" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070891" secondary="lipoteichoic acid binding" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034189" secondary="very-low-density lipoprotein particle binding" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" secondary="protein-containing complex binding" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050829" secondary="defense response to Gram-negative bacterium" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071224" secondary="cellular response to peptidoglycan" version="SP_165"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-14036387" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0110089" secondary="regulation of hippocampal neuron apoptotic process" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032499" secondary="detection of peptidoglycan" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901980" secondary="positive regulation of inward rectifier potassium channel activity" version="SP_165"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5UD8" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901800" secondary="positive regulation of proteasomal protein catabolic process" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990782" secondary="protein tyrosine kinase binding" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097028" secondary="dendritic cell differentiation" version="SP_165"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8N5H8" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010875" secondary="positive regulation of cholesterol efflux" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900015" secondary="regulation of cytokine production involved in inflammatory response" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000350" secondary="positive regulation of CD40 signaling pathway" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032675" secondary="regulation of interleukin-6 production" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902531" secondary="regulation of intracellular signal transduction" version="SP_165"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Z0I" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001530" secondary="lipopolysaccharide binding" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050921" secondary="positive regulation of chemotaxis" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903376" secondary="regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002931" secondary="response to ischemia" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903082" secondary="positive regulation of C-C chemokine receptor CCR7 signaling pathway" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0150062" secondary="complement-mediated synapse pruning" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071333" secondary="cellular response to glucose stimulus" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042834" secondary="peptidoglycan binding" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050714" secondary="positive regulation of protein secretion" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030169" secondary="low-density lipoprotein particle binding" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050850" secondary="positive regulation of calcium-mediated signaling" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900016" secondary="negative regulation of cytokine production involved in inflammatory response" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0120146" secondary="sulfatide binding" version="SP_165"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YMQ" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902227" secondary="negative regulation of macrophage colony-stimulating factor signaling pathway" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002862" secondary="negative regulation of inflammatory response to antigenic stimulus" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905581" secondary="positive regulation of low-density lipoprotein particle clearance" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032691" secondary="negative regulation of interleukin-1 beta production" version="SP_165"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6Z0G" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034136" secondary="negative regulation of toll-like receptor 2 signaling pathway" version="SP_165"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000373113" version="SP_165" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050730" secondary="regulation of peptidyl-tyrosine phosphorylation" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097062" secondary="dendritic spine maintenance" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045672" secondary="positive regulation of osteoclast differentiation" version="SP_165"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6XDS" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903078" secondary="positive regulation of protein localization to plasma membrane" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010891" secondary="negative regulation of sequestering of triglyceride" version="SP_165"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8WYN6" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034241" secondary="positive regulation of macrophage fusion" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002588" secondary="positive regulation of antigen processing and presentation of peptide antigen via MHC class II" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034151" secondary="regulation of toll-like receptor 6 signaling pathway" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032008" secondary="positive regulation of TOR signaling" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0150079" secondary="negative regulation of neuroinflammatory response" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005543" secondary="phospholipid binding" version="SP_165"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013783" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010983" secondary="positive regulation of high-density lipoprotein particle clearance" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006911" secondary="phagocytosis, engulfment" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010887" secondary="negative regulation of cholesterol storage" version="SP_165"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_061838.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032720" secondary="negative regulation of tumor necrosis factor production" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905805" secondary="excitatory synapse pruning" version="SP_165"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2172127" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008429" secondary="phosphatidylethanolamine binding" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140052" secondary="cellular response to oxidised low-density lipoprotein particle stimulus" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061518" secondary="microglial cell proliferation" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014067" secondary="negative regulation of phosphatidylinositol 3-kinase signaling" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038160" secondary="CXCL12-activated CXCR4 signaling pathway" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001774" secondary="microglial cell activation" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033674" secondary="positive regulation of kinase activity" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044853" secondary="plasma membrane raft" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070392" secondary="detection of lipoteichoic acid" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071396" secondary="cellular response to lipid" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035176" secondary="social behavior" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050766" secondary="positive regulation of phagocytosis" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001934" secondary="positive regulation of protein phosphorylation" version="SP_165"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001258750.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019209" secondary="kinase activator activity" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045088" secondary="regulation of innate immune response" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045728" secondary="respiratory burst after phagocytosis" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034351" secondary="negative regulation of glial cell apoptotic process" version="SP_165"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013106" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905907" secondary="negative regulation of amyloid fibril formation" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006959" secondary="humoral immune response" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034144" secondary="negative regulation of toll-like receptor 4 signaling pathway" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034185" secondary="apolipoprotein binding" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038023" secondary="signaling receptor activity" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008289" secondary="lipid binding" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071640" secondary="regulation of macrophage inflammatory protein 1 alpha production" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901076" secondary="positive regulation of engulfment of apoptotic cell" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032497" secondary="detection of lipopolysaccharide" version="SP_165"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0150094" secondary="amyloid-beta clearance by cellular catabolic process" version="SP_165"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MEPLRLLILLFVTELSGAHNTTVFQGVAGQSLQVSCPYDSMKHWGRRKAWCRQLGEKGPCQRVVSTHNLWLLSFLRRWNGSTAITDDTLGGTLTITLRNLQPHDAGLYQCQSLHGSEADTLRKVLVEVLADPLDHRDAGDLWFPGESESFEDAHVEHSISRSLLEGEIPFPPTSILLLLACIFLIKILAASALWAAAWHGQKPGTHPPSELDCGHDPGYQLQTLPGLRDT</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-25818-1" id="2968958">
                <names>
                    <shortLabel>235rw3r-2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-14036364" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25818-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>2968953</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="2968959">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-14036374" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>2968955</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="2968960">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-14036373" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>2968956</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">2C</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-25818-3" id="2968961">
                <names>
                    <shortLabel>trem1-tyrobp-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-14036382" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-25818-3" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>2968954</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="2968962">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-14036385" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>2968955</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="2968963">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-14036384" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>2968957</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">2C</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
