IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ ni-1997-1 yeast Saccharomyces cerevisiae Baker's yeast chemical rna modification plus base pairing prediction chemical rna modification plus base pairing prediction chemical rna modification plus base pairing prediction primer extension assay primer extension assay primer extension assay Ni J., Tien AL., Fournier MJ. primer extension assay was performed after treating RNA with CMC to detect pseudouridines Cell 1997 imex curation Only protein-protein interactions imex curation snr3 yeast small nucleolar RNA 3 yeast snorna small nucleolar rna snoRNA snorna yeast Saccharomyces cerevisiae Baker's yeast AACUUUGUCCUAAAGUACUAAUCCACCGCAUUAGACAGUACGAAGAUCGAGCUAUUUAUUUGAACACUCGGUCUUAUUCGUGAUAAGCGUAAUGUGGAGAGAUCAAUUUCCGGGUCAUUUAUAAGAACUCGAGUGGAUUGCUAGUUGUUUUGAUUAGCUGAAUGAGACUCGAGUGUCAGAAGAUGACUAUAUUU rrna 25s yeast Ribosomal RNA 25S Yeast rrna ribosomal rna rRNA rrna yeast Saccharomyces cerevisiae Baker's yeast GUUUGACCUCAAAUCAGGUAGGAGUACCCGCUGAACUUAAGCAUAUCAAUAAGCGGAGGAAAAGAAACCAACCGGGAUUGCCUUAGUAACGGCGAGUGAAGCGGCAAAAGCUCAAAUUUGAAAUCUGGUACCUUCGGUGCCCGAGUUGUAAUUUGGAGAGGGCAACUUUGGGGCCGUUCCUUGUCUAUGUUCCUUGGAACAGGACGUCAUAGAGGGUGAGAAUCCCGUGUGGCGAGGAGUGCGGUUCUUUGUAAAGUGCCUUCGAAGAGUCGAGUUGUUUGGGAAUGCAGCUCUAAGUGGGUGGUAAAUUCCAUCUAAAGCUAAAUAUUGGCGAGAGACCGAUAGCGAACAAGUACAGUGAUGGAAAGAUGAAAAGAACUUUGAAAAGAGAGUGAAAAAGUACGUGAAAUUGUUGAAAGGGAAGGGCAUUUGAUCAGACAUGGUGUUUUGUGCCCUCUGCUCCUUGUGGGUAGGGGAAUCUCGCAUUUCACUGGGCCAGCAUCAGUUUUGGUGGCAGGAUAAAUCCAUAGGAAUGUAGCUUGCCUCGGUAAGUAUUAUAGCCUGUGGGAAUACUGCCAGCUGGGACUGAGGACUGCGACGUAAGUCAAGGAUGCUGGCAUAAUGGUUAUAUGCCGCCCGUCUUGAAACACGGACCAAGGAGUCUAACGUCUAUGCGAGUGUUUGGGUGUAAAACCCAUACGCGUAAUGAAAGUGAACGUAGGUUGGGGCCUCGCAAGAGGUGCACAAUCGACCGAUCCUGAUGUCUUCGGAUGGAUUUGAGUAAGAGCAUAGCUGUUGGGACCCGAAAGAUGGUGAACUAUGCCUGAAUAGGGUGAAGCCAGAGGAAACUCUGGUGGAGGCUCGUAGCGGUUCUGACGUGCAAAUCGAUCGUCGAAUUUGGGUAUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCUGCCGAAGUUUCCCUCAGGAUAGCAGAAGCUCGUAUCAGUUUUAUGAGGUAAAGCGAAUGAUUAGAGGUUCCGGGGUCGAAAUGACCUUGACCUAUUCUCAAACUUUAAAUAUGUAAGAAGUCCUUGUUACUUAAUUGAACGUGGACAUUUGAAUGAAGAGCUUUUAGUGGGCCAUUUUUGGUAAGCAGAACUGGCGAUGCGGGAUGAACCGAACGUAGAGUUAAGGUGCCGGAAUACACGCUCAUCAGACACCACAAAAGGUGUUAGUUCAUCUAGACAGCCGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAAGGAGUGUGUAACAACUCACCGGCCGAAUGAACUAGCCCUGAAAAUGGAUGGCGCUCAAGCGUGUUACCUAUACUCUACCGUCAGGGUUGAUAUGAUGCCCUGACGAGUAGGCAGGCGUGGAGGUCAGUGACGAAGCCUAGACCGUAAGGUCGGGUCGAACGGCCUCUAGUGCAGAUCUUGGUGGUAGUAGCAAAUAUUCAAAUGAGAACUUUGAAGACUGAAGUGGGGAAAGGUUCCACGUCAACAGCAGUUGGACGUGGGUUAGUCGAUCCUAAGAGAUGGGGAAGCUCCGUUUCAAAGGCCUGAUUUUAUGCAGGCCACCAUCGAAAGGGAAUCCGGUUAAGAUUCCGGAACCUGGAUAUGGAUUCUUCACGGUAACGUAACUGAAUGUGGAGACGUCGGCGCGAGCCCUGGGAGGAGUUAUCUUUUCUUCUUAACAGCUUAUCACCCCGGAAUUGGUUUAUCCGGAGAUGGGGUCUUAUGGCUGGAAGAGGCCAGCACCUUUGCUGGCUCCGGUGCGCUUGUGACGGCCCGUGAAAAUCCACAGGAAGGAAUAGUUUUCAUGCCAGGUCGUACUGAUAACCGCAGCAGGUCUCCAAGGUGAACAGCCUCUAGUUGAUAGAAUAAUGUAGAUAAGGGAAGUCGGCAAAAUAGAUCCGUAACUUCGGGAUAAGGAUUGGCUCUAAGGGUCGGGUAGUGAGGGCCUUGGUCAGACGCAGCGGGCGUGCUUGUGGACUGCUUGGUGGGGCUUGCUCUGCUAGGCGGACUACUUGCGUGCCUUGUUGUAGACGGCCUUGGUAGGUCUCUUGUAGACCGUCGCUUGCUACAAUUAACGAUCAACUUAGAACUGGUACGGACAAGGGGAAUCUGACUGUCUAAUUAAAACAUAGCAUUGCGAUGGUCAGAAAGUGAUGUUGACGCAAUGUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAAGAAAUUCAACCAAGCGCGGGUAAACGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGAUUAACGAGAUUCCCACUGUCCCUAUCUACUAUCUAGCGAAACCACAGCCAAGGGAACGGGCUUGGCAGAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUAGUUUGACAUUGUGAAGAGACAUAGAGGGUGUAGAAUAAGUGGGAGCUUCGGCGCCAGUGAAAUACCACUACCUUUAUAGUUUCUUUACUUAUUCAAUGAAGCGGAGCUGGAAUUCAUUUUCCACGUUCUAGCAUUCAAGGUCCCAUUCGGGGCUGAUCCGGGUUGAAGACAUUGUCAGGUGGGGAGUUUGGCUGGGGCGGCACAUCUGUUAAACGAUAACGCAGAUGUCCUAAGGGGGGCUCAUGGAGAACAGAAAUCUCCAGUAGAACAAAAGGGUAAAAGCCCCCUUGAUUUUGAUUUUCAGUGUGAAUACAAACCAUGAAAGUGUGGCCUAUCGAUCCUUUAGUCCCUCGGAAUUUGAGGCUAGAGGUGCCAGAAAAGUUACCACAGGGAUAACUGGCUUGUGGCAGUCAAGCGUUCAUAGCGACAUUGCUUUUUGAUUCUUCGAUGUCGGCUCUUCCUAUCAUACCGAAGCAGAAUUCGGUAAGCGUUGGAUUGUUCACCCACUAAUAGGGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAAUGUUACCGCAAUAGUAAUUGAACUUAGUACGAGAGGAACAGUUCAUUCGGAUAAUUGGUUUUUGCGGCUGUCUGAUCAGGCAUUGCCGCGAAGCUACCAUCCGCUGGAUUAUGGCUGAACGCCUCUAAGUCAGAAUCCAUGCUAGAACGCGGUGAUUUCUUUGCUCCACACAAUAUAGAUGGAUACGAAUAAGGCGUCCUUGUGGCGUCGCUGAACCAUAGCAGGCUAGCAACGGUGCACUUGGCGGAAAGGCCUUGGGUGCUUGCUGGCGAAUUGCAAUGUCAUUUUGCGUGGGGAUAAAUCAUUUGUAUACGACUUAGAUGUACAACGGGGUAUUGUAAGCAGUAGAGUAGCCUUGUUGUUACGAUCUGCUGAGAUUAAGCCUUUGUUGUCUGAUUUGU snr8 yeast small nucleolar RNA 8 snorna small nucleolar rna snoRNA snorna yeast Saccharomyces cerevisiae Baker's yeast AUGAUACAUAUUAAACAUGCCUUCUAUUCACUGUGCCAUCUUACAUCCGUAGGUGAUCAGAGGGGAAAAGAAGAGCUAGAGCAACUCCCACACUCAUGAGCGUCCUCAUACUGUUCUGGGCGCUUCUCACAGGUGCUUCUUUUAGUGUCUCCCAUUGGCCCAGAUCGGUAGCUGCGCGAGUGAGAUAUCU snr10_yeast_rna small nucleolar RNA 10 Yeast snorna small nucleolar rna snoRNA snorna yeast Saccharomyces cerevisiae Baker's yeast AACGCAAAUUUAACAGCCAUUCGUAACACGUACAGUAUCUCGUCGAGGUUGAACCCCUCCGGGGCGUUCUUGACCCAUGAAGAAUGUGGAUUGGUGUUGCAAUAUAUUUAUUAUUGGCUUGGACUGGAGAACAAAUUUAUCGAUCUUGGGUGCAACAGUCUUUCUGUCGUCUGUUUUUUAGCAGAUCUAAGGGUUUACCUUCGUGUGCCCGGAUGAGGACCGUUGCAAGGAUUGAUAAUACAACU rrna 18s yeast Ribosomal RNA 18S Yeast rrna ribosomal rna rRNA rrna yeast Saccharomyces cerevisiae Baker's yeast UAUCUGGUUGAUCCUGCCAGUAGUCAUAUGCUUGUCUCAAAGAUUAAGCCAUGCAUGUCUAAGUAUAAGCAAUUUAUACAGUGAAACUGCGAAUGGCUCAUUAAAUCAGUUAUCGUUUAUUUGAUAGUUCCUUUACUACAUGGUAUAACUGUGGUAAUUCUAGAGCUAAUACAUGCUUAAAAUCUCGACCCUUUGGAAGAGAUGUAUUUAUUAGAUAAAAAAUCAAUGUCUUCGGACUCUUUGAUGAUUCAUAAUAACUUUUCGAAUCGCAUGGCCUUGUGCUGGCGAUGGUUCAUUCAAAUUUCUGCCCUAUCAACUUUCGAUGGUAGGAUAGUGGCCUACCAUGGUUUCAACGGGUAACGGGGAAUAAGGGUUCGAUUCCGGAGAGGGAGCCUGAGAAACGGCUACCACAUCCAAGGAAGGCAGCAGGCGCGCAAAUUACCCAAUCCUAAUUCAGGGAGGUAGUGACAAUAAAUAACGAUACAGGGCCCAUUCGGGUCUUGUAAUUGGAAUGAGUACAAUGUAAAUACCUUAACGAGGAACAAUUGGAGGGCAAGUCUGGUGCCAGCAGCCGCGGUAAUUCCAGCUCCAAUAGCGUAUAUUAAAGUUGUUGCAGUUAAAAAGCUCGUAGUUGAACUUUGGGCCCGGUUGGCCGGUCCGAUUUUUUCGUGUACUGGAUUUCCAACGGGGCCUUUCCUUCUGGCUAACCUUGAGUCCUUGUGGCUCUUGGCGAACCAGGACUUUUACUUUGAAAAAAUUAGAGUGUUCAAAGCAGGCGUAUUGCUCGAAUAUAUUAGCAUGGAAUAAUAGAAUAGGACGUUUGGUUCUAUUUUGUUGGUUUCUAGGACCAUCGUAAUGAUUAAUAGGGACGGUCGGGGGCAUCAGUAUUCAAUUGUCAGAGGUGAAAUUCUUGGAUUUAUUGAAGACUAACUACUGCGAAAGCAUUUGCCAAGGACGUUUUCAUUAAUCAAGAACGAAAGUUAGGGGAUCGAAGAUGAUCAGAUACCGUCGUAGUCUUAACCAUAAACUAUGCCGACUAGGGAUCGGGUGGUGUUUUUUUAAUGACCCACUCGGCACCUUACGAGAAAUCAAAGUCUUUGGGUUCUGGGGGGAGUAUGGUCGCAAGGCUGAAACUUAAAGGAAUUGACGGAAGGGCACCACCAGGAGUGGAGCCUGCGGCUUAAUUUGACUCAACACGGGGAAACUCACCAGGUCCAGACACAAUAAGGAUUGACAGAUUGAGAGCUCUUUCUUGAUUUUGUGGGUGGUGGUGCAUGGCCGUUCUUAGUUGGUGGAGUGAUUUGUCUGCUUAAUUGCGAUAACGAACGAGACCUUAACCUACUAAAUAGUGGUGCUAGCAUUUGCUGGUUAUCCACUUCUUAGAGGGACUAUCGGUUUCAAGCCGAUGGAAGUUUGAGGCAAUAACAGGUCUGUGAUGCCCUUAGACGUUCUGGGCCGCACGCGCGCUACACUGACGGAGCCAGCGAGUCUAACCUUGGCCGAGAGGUCUUGGUAAUCUUGUGAAACUCCGUCGUGCUGGGGAUAGAGCAUUGUAAUUAUUGCUCUUCAACGAGGAAUUCCUAGUAAGCGCAAGUCAUCAGCUUGCGUUGAUUACGUCCCUGCCCUUUGUACACACCGCCCGUCGCUAGUACCGAUUGAAUGGCUUAGUGAGGCCUCAGGAUCUGCUUAGAGAAGGGGGCAACUCCAUCUCAGAGCGGAGAAUUUGGACAAACUUGGUCAUUUAGAGGAACUAAAAGUCGUAACAAGGUUUCCGUAGGUGAACCUGCGGAAGGAUCAUUA snr31 yeast small nucleolar RNA 31 snorna small nucleolar rna snoRNA snorna yeast Saccharomyces cerevisiae Baker's yeast GAAGCAAAAUUACACCAUGAGUUCCUAUUAACGUCAGCCUCUUUUGUACUCAUAAUGUGGCUUCGGAUGUUUGAUGGGCGUUGCUUCAGUGCGUACGGCUCAUGGUAGAUUAAUUAUUAGAAAGAUGUAUCUCCAGCUGUUGAUAUUAGAGGGGGAAGCCUUUCUCUUUCACCUCGCCUUUUUAAACACCUGAUACAGUUGGUCAUGAUUCGUUCUACAUUUUAA snr32 yeast small nucleolar RNA 32 Yeast snorna small nucleolar rna snoRNA snorna yeast Saccharomyces cerevisiae Baker's yeast AACAUCAUAAUUAUAUCGCGAAUGUACUACUAGUAUAUGCAGUUUUCUUAAAAUUGCAGGGAAUGACUAAAAGCCCACGUUUUUCCCACUUUUAGUAGUACUGAAGCGUAGAUAGAUUGAACGUUGCUGGGCGCCUGGUGUUGAUCAUUUCUGAAAUGAGAUAUUGGGAAUCAGCUGUAUCUACAUUU snr33 yeast small nucleolar RNA 33 snorna small nucleolar rna snoRNA snorna yeast Saccharomyces cerevisiae Baker's yeast AAGCUUAAUGCCCUCUUUGUACGAUGGUGUCACUCUAAAAUUAUUUACGUAAUUUAAUUGGAUGUGAUAUCAAGCACUAGUUUUGUUUGGAGGAGCAGAGAUUGAAAGCCUAGCUUUUACACCGGUUUGAGUCGGUUCCUUCGUUUUCUUAGUUGGAAUUGAUAUAGAAGUGUGUGGACAAUC snr34 yeast small nucleolar RNA 34 snorna small nucleolar rna snoRNA snorna yeast Saccharomyces cerevisiae Baker's yeast GAAUCAAAAAUUUAUUUUUUACACGGAAACGAUGCCACAGUUGACUGAACCUGUCUUCUAACAGUAGUUAAUUGCCAGUAUUUCAAACAAGAUUUGAAAUACGAGUUUCCCAGAAUAAUUUAUUUGGACAGGAUAGGAAGUCCGAUUUCUGUGUUGUCUCAAACGAGGCGAUAGAAUUGGGAUGUCGAAGAAAGUCUACAUUA snr37_yeast_rna small nucleolar RNA 37 Yeast snorna small nucleolar rna snoRNA snorna yeast Saccharomyces cerevisiae Baker's yeast AACAUCAGUAGUGGUUAAUACUAUCUUUAGAUAAUAUUAAUUUCAUUAUACCAUAGAAACCUAAAGAUUAGGUUAUUUUCGUUCUUCAUGUUAUGGAGUGUGAGUGAUGAGGAGCUUGCUCUUUUAAGCUCAUAUUACGUAAUAAGUUAAUACUGGAGCGAGAAUAAUUUAAAUCAUUUCAUCAUAACCCAUAGCUGAAUGAACUUUGACUACUCCUAAACAAAGUAGUAACAAUUUUCAUUUCGUUUCCGGUUUCUUAGAUCGAAUAUUAUUCUGAGGAAAUUCCCUGAUUACAUAUCAGGGAAAGGUUCGCGUUUUUAGAGAAUUGCGUAAUGCGAUUUGAAAGUUUAAAUUCCUAAGCGACUCUUCUUCAUGAUAAGACAGUU snr42 yeast small nucleolar RNA 42 Yeast snorna small nucleolar rna snoRNA snorna yeast Saccharomyces cerevisiae Baker's yeast AUAACAAUUUGUGAUGCUUUAGGGAGCCUAUUGUUUGAUGGUUUAUAGGAGCCGGAUUUGUCUUUUUGACUAAUUUUCAACCUAUUCUUACUUCCAAAACUGUUGCAAUGGCUCUCGUUUUUUUUAAAUUUUUCUCUUUUCUCUUCUUUGGCAUAGUUUAUUUUUAAUAAAUUAUUUCAGGGUGAGAUAGAGAAAGGAUAAUGAGUAUCGUAGAUAAAUCUUCGGUUCCGAAUAGUGUAACUGUUGGUGCUGAGGUAAUCCAUCUUUAAAACCAUCGCCGUUAGAGGUUGCUUCUGAUAUUUUCGGUUAAGCGACCCAUGAAAUGGUGAUGACCUGAGGUAUGGAACAUCU snr46 yeast small nuclear RNA 46 snorna small nucleolar rna snoRNA snorna yeast Saccharomyces cerevisiae Baker's yeast AUGGCCUCUUCGAAGAUCCGUAGAUUUUGCAUUUUUGCGGUGGUUUAUGGAUUCAAAGCGAGGCCUAAAUUAACGAUCAUGUCUUUGCUAUUAUAUCAGAGGGCAUAUCAUUGAAUUUCCGAUUUCCAAAGGGAAGAAAAUAAAUAAAGUUGUGCUAUUUCCAUGCAUCCUUUUUUCUUUCAUUCAAUGACACAUAC snr3 rrna25s-1 1937840 N/A 1937841 unspecified role unspecified role neutral component neutral component N/A 1937842 unspecified role unspecified role neutral component neutral component Pseudouridine rna chemical modification RNA chemical modification RNA chemical modification post-transcriptional modification rna chemical modification certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Fig 1, Table 1 rrna 25s yeast-snr8 yeast-1 1937840 N/A 1937843 unspecified role unspecified role neutral component neutral component a185c mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain false N/A 1937842 unspecified role unspecified role neutral component neutral component Pseudouridine rna chemical modification RNA chemical modification RNA chemical modification post-transcriptional modification rna chemical modification certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Fig1A, Table 1, Fig3 rrna 25s yeast-snr10_yeast_rna-1 1937840 N/A 1937844 unspecified role unspecified role neutral component neutral component N/A 1937842 unspecified role unspecified role neutral component neutral component Pseudouridine rna chemical modification RNA chemical modification RNA chemical modification post-transcriptional modification rna chemical modification certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Table 1, Fig3 rrna18s snr31-1 1937840 N/A 1937845 unspecified role unspecified role neutral component neutral component Pseudouridine rna chemical modification RNA chemical modification RNA chemical modification post-transcriptional modification rna chemical modification certain certain sequence position certain certain certain sequence position certain false N/A 1937846 unspecified role unspecified role neutral component neutral component physical association physical association false false false Table1. Fig3 snr32 rrna25s-1 1937840 N/A 1937847 unspecified role unspecified role neutral component neutral component N/A 1937842 unspecified role unspecified role neutral component neutral component Pseudouridine rna chemical modification RNA chemical modification RNA chemical modification post-transcriptional modification rna chemical modification certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Table1, Fig3 rrna 25s yeast-snr33 yeast-1 1937840 N/A 1937848 unspecified role unspecified role neutral component neutral component N/A 1937842 unspecified role unspecified role neutral component neutral component Pseudouridine rna chemical modification RNA chemical modification RNA chemical modification post-transcriptional modification rna chemical modification certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Table1, Fig3 rrna 25s yeast-snr34 yeast-1 1937840 N/A 1937842 unspecified role unspecified role neutral component neutral component Pseudouridine rna chemical modification RNA chemical modification RNA chemical modification post-transcriptional modification rna chemical modification certain certain sequence position certain certain certain sequence position certain false N/A 1937849 unspecified role unspecified role neutral component neutral component physical association physical association false false false Table1, Fig3 snr37 rrna25-1 1937840 N/A 1937842 unspecified role unspecified role neutral component neutral component Pseudouridine rna chemical modification RNA chemical modification RNA chemical modification post-transcriptional modification rna chemical modification certain certain sequence position certain certain certain sequence position certain false N/A 1937850 unspecified role unspecified role neutral component neutral component physical association physical association false false false Table 1 rrna25s snr42-1 1937840 N/A 1937851 unspecified role unspecified role neutral component neutral component N/A 1937842 unspecified role unspecified role neutral component neutral component Pseudouridine rna chemical modification RNA chemical modification RNA chemical modification post-transcriptional modification rna chemical modification certain certain sequence position certain certain certain sequence position certain false physical association physical association false false false Table 1 Fig 3 rrna25s snr46-1 1937840 N/A 1937842 unspecified role unspecified role neutral component neutral component Pseudouridine rna chemical modification RNA chemical modification RNA chemical modification post-transcriptional modification rna chemical modification certain certain sequence position certain certain certain sequence position certain false N/A 1937852 unspecified role unspecified role neutral component neutral component physical association physical association false false false Table 1