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        <source releaseDate="2015-04-10+01:00">
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                <shortLabel>MINT</shortLabel>
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                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
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                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
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            <experimentDescription id="1778843">
                <names>
                    <shortLabel>szl_ma-2015-1</shortLabel>
                    <fullName>K153R polymorphism in myostatin gene increases the rate of promyostatin activation by furin.</fullName>
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                            <shortLabel>in vitro</shortLabel>
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                        <shortLabel>enzymatic study</shortLabel>
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                    <names>
                        <shortLabel>weight by comassie</shortLabel>
                        <fullName>molecular weight estimation by coomasie staining</fullName>
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                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Szláma G., Trexler M., Buday L., Patthy L.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">szlama.gyorgy@ttk.mta.hu</attribute>
                    <attribute name="journal" nameAc="MI:0885">FEBS Lett. (0014-5793)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2015</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
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                <names>
                    <shortLabel>gdf8_human</shortLabel>
                    <fullName>Growth/differentiation factor 8</fullName>
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                    <alias typeAc="MI:0302" type="gene name synonym">GDF8</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Myostatin</alias>
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                        <fullName>Homo sapiens</fullName>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6EQV" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990000" secondary="amyloid fibril formation" version="SP_246"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2173789" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005802" secondary="trans-Golgi network" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" secondary="metal ion binding" version="SP_246"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5JXH" version="SP_246"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001276753.1"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000140564" version="SP_246" refType="gene"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UCZ5" version="SP_118" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032940" secondary="secretion by cell" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042277" secondary="peptide binding" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" secondary="extracellular region" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032911" secondary="negative regulation of transforming growth factor beta1 production" version="SP_246"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-977225" version="SP_246"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR034182" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009966" secondary="regulation of signal transduction" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016486" secondary="peptide hormone processing" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019058" secondary="viral life cycle" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" secondary="extracellular exosome" version="SP_246"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000483552" version="SP_246" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000610579" version="SP_246" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043043" secondary="peptide biosynthetic process" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004252" secondary="serine-type endopeptidase activity" version="SP_246"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032815" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016020" secondary="membrane" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030574" secondary="collagen catabolic process" version="SP_246"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29904N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0052548" secondary="regulation of endopeptidase activity" version="SP_246"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1056807" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YD3" version="SP_246"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090472" secondary="dibasic protein processing" version="SP_246"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1912420" version="SP_246"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000268171" version="SP_246" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045121" secondary="membrane raft" version="SP_246"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002884" version="SP_246"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000618099" version="SP_246" refType="transcript"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6HZB" version="SP_246"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023827" version="SP_246"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEGRGERTAFIKDQSAL</sequence>
            </interactor>
            <interactor id="1778846">
                <names>
                    <shortLabel>bmp1_human</shortLabel>
                    <fullName>Bone morphogenetic protein 1</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">Procollagen C-proteinase</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Mammalian tolloid protein</alias>
                    <alias typeAc="MI:0301" type="gene name">BMP1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">PCOLC</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P13497" version="SP_97" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6BTP" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008083" secondary="growth factor activity" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001502" secondary="cartilage condensation" version="SP_230"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001190.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001503" secondary="ossification" version="SP_230"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6BTQ" version="SP_230"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1474228" version="SP_230"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000306385" version="SP_230" refType="transcript"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR024079" version="SP_230"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6BTN" version="SP_230"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UL38" version="SP_97" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EDH" version="SP_230"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-33403N"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000152" version="SP_230"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2243919" version="SP_230"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029837" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007275" secondary="multicellular organism development" version="SP_230"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EDG" version="SP_230"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6BSL" version="SP_230"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016869227.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6BTO" version="SP_230"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P13497" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" secondary="extracellular region" version="SP_230"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR035914" version="SP_230"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q13292" version="SP_97" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K6F5" version="SP_125" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005509" secondary="calcium ion binding" version="SP_230"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1650814" version="SP_230"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-489827" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000742" version="SP_230"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8963896" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" secondary="Golgi apparatus" version="SP_230"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_006120.1"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011542919.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14874" version="SP_97" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q99422" version="SP_97" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6BSM" version="SP_230"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B2RN46" version="SP_125" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006026" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008233" secondary="peptidase activity" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001501" secondary="skeletal system development" version="SP_230"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015446" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061036" secondary="positive regulation of cartilage development" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031982" secondary="vesicle" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006508" secondary="proteolysis" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004252" secondary="serine-type endopeptidase activity" version="SP_230"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000859" version="SP_230"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018097" version="SP_230"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q99421" version="SP_97" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008270" secondary="zinc ion binding" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005125" secondary="cytokine activity" version="SP_230"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001506" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008237" secondary="metallopeptidase activity" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030154" secondary="cell differentiation" version="SP_230"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q13872" version="SP_97" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR034036" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" secondary="extracellular space" version="SP_230"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001881" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030199" secondary="collagen fibril organization" version="SP_230"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000168487" version="SP_230" refType="gene"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D3DSR0" version="SP_133" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q99423" version="SP_97" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2214320" version="SP_230"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004222" secondary="metalloendopeptidase activity" version="SP_230"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009030" version="SP_230"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000305714" version="SP_230" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDEEDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-23834-1" id="1778847">
                <names>
                    <shortLabel>furin-mstn-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-10171267" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-23834-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1778843</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1778848">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10171270" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1778844</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>weight by comassie</shortLabel>
                                    <fullName>molecular weight estimation by coomasie staining</fullName>
                                    <alias typeAc="MI:1041" type="synonym">weight by comassie</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0818" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1218596" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>enzyme target</shortLabel>
                                <fullName>enzyme target</fullName>
                                <alias typeAc="MI:0303" type="go synonym">substrate</alias>
                                <alias typeAc="MI:1041" type="synonym">substrate</alias>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0502" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-64" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1778849">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10171269" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1778845</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>weight by comassie</shortLabel>
                                    <fullName>molecular weight estimation by coomasie staining</fullName>
                                    <alias typeAc="MI:1041" type="synonym">weight by comassie</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0818" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1218596" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>enzyme</shortLabel>
                                <fullName>enzyme</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0501" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-46" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>cleavage</shortLabel>
                        <fullName>cleavage reaction</fullName>
                        <alias typeAc="MI:1041" type="synonym">cleavage</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0194" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49853" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f1</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-23834-2" id="1778850">
                <names>
                    <shortLabel>furin-mstn-2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-10171271" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-23834-2" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1778843</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1778851">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10171274" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1778844</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>weight by comassie</shortLabel>
                                    <fullName>molecular weight estimation by coomasie staining</fullName>
                                    <alias typeAc="MI:1041" type="synonym">weight by comassie</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0818" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1218596" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>enzyme target</shortLabel>
                                <fullName>enzyme target</fullName>
                                <alias typeAc="MI:0303" type="go synonym">substrate</alias>
                                <alias typeAc="MI:1041" type="synonym">substrate</alias>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0502" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-64" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1778852">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10171273" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1778846</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>weight by comassie</shortLabel>
                                    <fullName>molecular weight estimation by coomasie staining</fullName>
                                    <alias typeAc="MI:1041" type="synonym">weight by comassie</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0818" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1218596" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>enzyme</shortLabel>
                                <fullName>enzyme</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0501" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-46" refType="identity" refTypeAc="MI:0356"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>cleavage</shortLabel>
                        <fullName>cleavage reaction</fullName>
                        <alias typeAc="MI:1041" type="synonym">cleavage</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0194" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49853" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f2</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
