<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<entrySet level="2" version="5" minorVersion="4" xsi:schemaLocation="http://psi.hupo.org/mi/mif http://psidev.sourceforge.net/mi/rel25/src/MIF254.xsd" xmlns="http://psi.hupo.org/mi/mif" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <entry>
        <source releaseDate="2015-08-25+01:00">
            <names>
                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
                <alias typeAc="MI:1041" type="synonym">IntAct</alias>
                <alias typeAc="MI:1041" type="synonym">intact</alias>
            </names>
            <bibref>
                <xref>
                    <primaryRef db="pubmed" dbAc="MI:0446" id="14681455" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
            </bibref>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0469" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-10" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="19850723" refType="method reference" refTypeAc="MI:0357"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14681455" refType="primary-reference" refTypeAc="MI:0358"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="22121220" refType="method reference" refTypeAc="MI:0357"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
                <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
                <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
                <attribute name="url">http://www.ebi.ac.uk/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="1854316">
                <names>
                    <shortLabel>emery-2004-1</shortLabel>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="15049817" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-10902008" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26556" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="559292">
                        <names>
                            <shortLabel>yeast</shortLabel>
                            <fullName>Saccharomyces cerevisiae</fullName>
                            <alias typeAc="MI:1041" type="synonym">Baker's yeast</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>cosedimentation</shortLabel>
                        <fullName>cosedimentation</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0027" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1038" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>northern blot</shortLabel>
                        <fullName>northern blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">northen</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0929" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="414220" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1812930" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Emery B., de la Cruz J., Rocak S., Deloche O., Linder P.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">Patrick.Linder@medecine.unige.ch</attribute>
                    <attribute name="journal" nameAc="MI:0885">Molecular microbiology</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2004</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1854317">
                <names>
                    <shortLabel>rrna 27sa2</shortLabel>
                    <fullName>presursor ribosomal RNA 27SA2 yeast</fullName>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-10894903" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>rrna</shortLabel>
                        <fullName>ribosomal rna</fullName>
                        <alias typeAc="MI:0303" type="go synonym">rRNA</alias>
                        <alias typeAc="MI:1041" type="synonym">rrna</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0608" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-933536" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="559292">
                    <names>
                        <shortLabel>yeast</shortLabel>
                        <fullName>Saccharomyces cerevisiae</fullName>
                        <alias typeAc="MI:1041" type="synonym">Baker's yeast</alias>
                    </names>
                </organism>
            </interactor>
            <interactor id="1854318">
                <names>
                    <shortLabel>has1_yeast</shortLabel>
                    <fullName>ATP-dependent RNA helicase HAS1</fullName>
                    <alias typeAc="MI:0305" type="locus name">YMR290C</alias>
                    <alias typeAc="MI:0301" type="gene name">HAS1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Helicase associated with SET1 protein 1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q03532" version="SP_65" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="sgd" dbAc="MI:0484" id="S000004903"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003723" secondary="RNA binding" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006364" secondary="rRNA processing" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6EM1" version="SP_190"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000629" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000462" secondary="maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6EM5" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6CB1" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ELZ" version="SP_190"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8170" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5Z3G" version="SP_190"/>
                    <secondaryRef db="ensemblfungi" id="YMR290C" version="SP_190" refType="gene"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR044773" version="SP_190"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q03532"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-4396N"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014001" version="SP_190"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011545" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030686" secondary="90S preribosome" version="SP_190"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014014" version="SP_190"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027417" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005730" secondary="nucleolus" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6EM3" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005635" secondary="nuclear envelope" version="SP_190"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001650" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1990417" secondary="snoRNA release from pre-rRNA" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008186" secondary="ATPase, acting on RNA" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000463" secondary="maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030687" secondary="preribosome, large subunit precursor" version="SP_190"/>
                    <secondaryRef db="ensemblfungi" id="YMR290C_mRNA" version="SP_190" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003724" secondary="RNA helicase activity" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140603" secondary="ATP hydrolysis activity" version="SP_190"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6C0F" version="SP_190"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_014017.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6EM4" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042273" secondary="ribosomal large subunit biogenesis" version="SP_190"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042274" secondary="ribosomal small subunit biogenesis" version="SP_190"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D6W0B7" version="SP_99" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR025313" version="SP_190"/>
                    <secondaryRef db="ensemblfungi" id="YMR290C" version="SP_190" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="559292">
                    <names>
                        <shortLabel>yeast</shortLabel>
                        <fullName>Saccharomyces cerevisiae</fullName>
                        <alias typeAc="MI:1041" type="synonym">Baker's yeast</alias>
                    </names>
                </organism>
                <sequence>MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASKVPLNEYEFPENKIANVQSQLEKLIKSNYYLHQTAKDGYRSYLQAYASHSLKTVYQIDKLDLAKVAKSYGFPVPPKVNITIGASGKTPNTKRRKTHK</sequence>
                <attributeList>
                    <attribute name="crc64">EE15D51A7F6BE1A2</attribute>
                </attributeList>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-26556-1" id="1854319">
                <names>
                    <shortLabel>has1p_27s rna-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-10902015" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-26556-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1854316</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1854320">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10902018" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1854317</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1854321">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10902017" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1854318</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1854322">
                                <names>
                                    <shortLabel>tag</shortLabel>
                                    <fullName>HA tag</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-10902034" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>ha tag</shortLabel>
                                        <fullName>ha tag</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">YPYDVPDYA epitope tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">YPYDVPDYA epitope tag</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0520" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456513" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>n-term range</shortLabel>
                                                <fullName>n-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">n-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1040" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929795" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>n-term range</shortLabel>
                                                <fullName>n-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">n-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1040" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929795" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Fig9</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
