IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ zhang-2014a-1 KAI1/CD82, a partner of tissue inhibitor of metalloproteinase-1 in human pancreatic carcinoma cells in vitro In vitro crosslink cross-linking study crosslink tag visualisation tag visualisation Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 29-05-2014: Jiexin Zhang, Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University Sulfo-SEBD was used as cross-linking agent. This agent contains a biotin region that was used to visualize it via a streptavidin-peroxidase conjugate. hanxiao@njmu.edu.cn Oncotarget 2014 Only protein-protein interactions imex curation Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 2017 zhang-2014a-5 KAI1/CD82, a partner of tissue inhibitor of metalloproteinase-1 in human pancreatic carcinoma cells in vitro In vitro atomic force microsc atomic force microscopy AFM AFM atomic force microsc predetermined predetermined participant predetermined Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 29-05-2014: Jiexin Zhang, Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University Bait was attached to the ATM cantilever via a PEG linker. Prey was immbolized on a glass coverslip. Information about the CD63 construct was provided by the author. hanxiao@njmu.edu.cn Oncotarget 2014 Only protein-protein interactions imex curation Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 2017 zhang-2014a-3 KAI1/CD82, a partner of tissue inhibitor of metalloproteinase-1 in human pancreatic carcinoma cells human-panc1 Homo sapiens pancreatic carcinoma cell line PANC-1 panc1 Human pancreatic carcinoma cell line PANC-1 Established from a pancreatic carcinoma of ductal origin from a 56-year-old Caucasian male. Cells possess the type B phenotype for G6PD. anti bait coip anti bait coimmunoprecipitation anti bait coip sequence tag sequence tag identification sequence tag Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 29-05-2014: Jiexin Zhang, Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University hanxiao@njmu.edu.cn Oncotarget 2014 Only protein-protein interactions imex curation Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 2017 zhang-2014a-2 KAI1/CD82, a partner of tissue inhibitor of metalloproteinase-1 in human pancreatic carcinoma cells human-panc1 Homo sapiens pancreatic carcinoma cell line PANC-1 panc1 Human pancreatic carcinoma cell line PANC-1 Established from a pancreatic carcinoma of ductal origin from a 56-year-old Caucasian male. Cells possess the type B phenotype for G6PD. anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 29-05-2014: Jiexin Zhang, Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University hanxiao@njmu.edu.cn Oncotarget 2014 Only protein-protein interactions imex curation Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 2017 zhang-2014a-4 KAI1/CD82, a partner of tissue inhibitor of metalloproteinase-1 in human pancreatic carcinoma cells in vitro In vitro anti bait coip anti bait coimmunoprecipitation anti bait coip tag visualisation tag visualisation Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 29-05-2014: Jiexin Zhang, Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University Binding of the prey was monitored by measuring radioactivity of co-immunoprecipitated sample by use of a gamma-counter. hanxiao@njmu.edu.cn Oncotarget 2014 Only protein-protein interactions imex curation Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 2017 zhang-2014a-6 KAI1/CD82, a partner of tissue inhibitor of metalloproteinase-1 in human pancreatic carcinoma cells human-panc1 Homo sapiens pancreatic carcinoma cell line PANC-1 panc1 Human pancreatic carcinoma cell line PANC-1 Established from a pancreatic carcinoma of ductal origin from a 56-year-old Caucasian male. Cells possess the type B phenotype for G6PD. confocal microscopy confocal microscopy immunostaining immunostaining Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 29-05-2014: Jiexin Zhang, Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University hanxiao@njmu.edu.cn Oncotarget 2014 Only protein-protein interactions imex curation Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 2017 zhang-2014a-7 KAI1/CD82, a partner of tissue inhibitor of metalloproteinase-1 in human pancreatic carcinoma cells human-mcf7 Homo sapiens mammary carcinoma cells mcf7 mammary carcinoma cells confocal microscopy confocal microscopy immunostaining immunostaining Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 29-05-2014: Jiexin Zhang, Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University hanxiao@njmu.edu.cn Oncotarget 2014 Only protein-protein interactions imex curation Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 2017 zhang-2014a-8 KAI1/CD82, a partner of tissue inhibitor of metalloproteinase-1 in human pancreatic carcinoma cells human-mammary epithelium Human mammary epithelium mammary_epithelium Mammary epithelium confocal microscopy confocal microscopy immunostaining immunostaining Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 29-05-2014: Jiexin Zhang, Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University hanxiao@njmu.edu.cn Oncotarget 2014 Only protein-protein interactions imex curation Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 2017 zhang-2014a-9 KAI1/CD82, a partner of tissue inhibitor of metalloproteinase-1 in human pancreatic carcinoma cells human-breast_cancer Homo sapiens breast cancer tissue breast_cancer Breast cancer tissue confocal microscopy confocal microscopy immunostaining immunostaining Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 29-05-2014: Jiexin Zhang, Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University Ductal Carcinoma In SItu tissue was used in this experiment. hanxiao@njmu.edu.cn Oncotarget 2014 Only protein-protein interactions imex curation Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 2017 zhang-2014a-10 KAI1/CD82, a partner of tissue inhibitor of metalloproteinase-1 in human pancreatic carcinoma cells human-pancreas_cancer Human pancreatic tissue pancreas_cancer Pancreatic cancer tissue confocal microscopy confocal microscopy immunostaining immunostaining Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 29-05-2014: Jiexin Zhang, Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University Pancreatic Ductal Carcinoma tissue was used in this experiment. hanxiao@njmu.edu.cn Oncotarget 2014 Only protein-protein interactions imex curation Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 2017 zhang-2014a-11 KAI1/CD82, a partner of tissue inhibitor of metalloproteinase-1 in human pancreatic carcinoma cells human-pancreas Human pancreatic tissue pancreas confocal microscopy confocal microscopy immunostaining immunostaining Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 29-05-2014: Jiexin Zhang, Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University hanxiao@njmu.edu.cn Oncotarget 2014 Only protein-protein interactions imex curation Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J, Zhan S, Qiao N, Wu T, Zhang X, Zhu Y, Yang N, Sun Y, Zhang XA, Bleich D, Han X, Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X., Zhang J., Wu T., Zhan S., Qiao N., Zhang X., Zhu Y., Yang N., Sun Y., Zhang XA., Bleich D., Han X. 2017 timp1_human Metalloproteinase inhibitor 1 Tissue inhibitor of metalloproteinases 1 Erythroid-potentiating activity Fibroblast collagenase inhibitor TIMP1 CLGI TIMP protein protein human Homo sapiens Human MAPFEPLASGILLLLWLIAPSRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQSRHLACLPREPGLCTWQSLRSQIA cd82_human CD82 antigen Inducible membrane protein R2 C33 antigen IA4 Metastasis suppressor Kangai-1 Suppressor of tumorigenicity 6 protein Tetraspanin-27 CD82 KAI1 SAR2 TSPAN27 ST6 protein protein human Homo sapiens Human MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLGMVLSICLCRHVHSEDYSKVPKY cd63_human CD63 antigen Melanoma-associated antigen ME491 Ocular melanoma-associated antigen OMA81H Granulophysin Tetraspanin-30 Lysosomal-associated membrane protein 3 CD63 MLA1 TSPAN30 Lysosome integral membrane protein 1 protein protein human Homo sapiens Human MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLSQTIIQGATPGSLLPVVIIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEKAIHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKSIRSGYEVM cd82-timp1-1 1562274 n/a 1562285 unspecified role unspecified role neutral component neutral component purified purified region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false crigr-cho chinese hamster ovary cell line cho chinese hamster ovary cell line Also called LR73 cells. n/a 1562286 unspecified role unspecified role neutral component neutral component purified purified extracellular domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n-terminal his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false c-terminal signal peptide tag tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human Homo sapiens Human direct interaction direct interaction false false false 3B timp1-timp1-1 1562274 n/a 1562285 unspecified role unspecified role neutral component neutral component purified purified region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false crigr-cho chinese hamster ovary cell line cho chinese hamster ovary cell line Also called LR73 cells. Stoichiometry: 2.0 direct interaction direct interaction false false false 3B cd82-timp1-3 1562275 n/a 1562286 unspecified role unspecified role bait bait purified purified extracellular domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n-terminal his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false c-terminal signal peptide tag tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false human Homo sapiens Human Stoichiometry: 1.0 n/a 1562285 unspecified role unspecified role prey prey purified purified region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false crigr-cho chinese hamster ovary cell line cho chinese hamster ovary cell line Also called LR73 cells. Stoichiometry: 1.0 1562304 1562300 direct interaction direct interaction false false false 1D Dissociation force = 35 pN cd63-timp1-4 1562275 n/a 1562287 unspecified role unspecified role bait bait purified purified second extraceulluar domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false c-terminal his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false n-terminal signal peptide tag tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human Stoichiometry: 1.0 n/a 1562285 unspecified role unspecified role prey prey purified purified region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false crigr-cho chinese hamster ovary cell line cho chinese hamster ovary cell line Also called LR73 cells. 1562311 1562307 direct interaction direct interaction false false false 3D Average dissociation force = 80 pN timp1-cd63-2 1562276 n/a 1562286 unspecified role unspecified role prey prey n/a 1562285 unspecified role unspecified role bait bait n/a 1562287 unspecified role unspecified role prey prey association association false false false 1A(I,II,III) timp1-cd63-3 1562277 N/A 1562287 unspecified role unspecified role prey prey n/a 1562286 unspecified role unspecified role prey prey n/a 1562285 unspecified role unspecified role bait bait association association false false false Fig1B timp1-cd82-1 1562278 n/a 1562285 unspecified role unspecified role bait bait purified purified region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false crigr-cho chinese hamster ovary cell line cho chinese hamster ovary cell line Also called LR73 cells. n/a 1562286 unspecified role unspecified role prey prey purified purified c-terminal signal peptide tag tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false n-terminal his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false extracellular domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false human Homo sapiens Human n/a 1562286 competitor competitor competitor prey prey purified purified c-terminal signal peptide tag tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range false extracellular domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain false n-terminal his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range false human Homo sapiens Human association association false false false 3C cd82-timp1-4 1562279 n/a 1562285 unspecified role unspecified role neutral component neutral component n/a 1562286 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false 2A cd82-timp1-5 1562280 n/a 1562286 unspecified role unspecified role neutral component neutral component n/a 1562285 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false 2A This colocalization was also found in a MCF7 cell line overexpressing TIM1. cd82-timp1-6 1562281 n/a 1562286 unspecified role unspecified role neutral component neutral component n/a 1562285 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false 2B cd82-timp1-7 1562282 n/a 1562285 unspecified role unspecified role neutral component neutral component n/a 1562286 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false 2B cd82-timp1-8 1562283 n/a 1562286 unspecified role unspecified role neutral component neutral component n/a 1562285 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false 2C cd82-timp1-9 1562284 n/a 1562286 unspecified role unspecified role neutral component neutral component n/a 1562285 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false 2C