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    <entry>
        <source releaseDate="2015-01-22Z">
            <names>
                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
                <alias typeAc="MI:1041" type="synonym">IntAct</alias>
                <alias typeAc="MI:1041" type="synonym">intact</alias>
            </names>
            <bibref>
                <xref>
                    <primaryRef db="pubmed" dbAc="MI:0446" id="14681455" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
            </bibref>
            <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0469" refType="identity" refTypeAc="MI:0356"/>
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                <secondaryRef db="pubmed" dbAc="MI:0446" id="22121220" refType="method reference" refTypeAc="MI:0357"/>
            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
                <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
                <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
                <attribute name="url">http://www.ebi.ac.uk/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="1767022">
                <names>
                    <shortLabel>ruan-2014-1</shortLabel>
                    <fullName>O-GlcNAc transferase enables AgRP neurons to suppress browning of white fat.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="25303527" refType="primary-reference" refTypeAc="MI:0358"/>
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                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-23619" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="10090">
                        <names>
                            <shortLabel>mouse-brain_hypothalamus</shortLabel>
                            <fullName>Mus musculus</fullName>
                        </names>
                        <tissue>
                            <names>
                                <shortLabel>hypothalamus</shortLabel>
                                <fullName>hypothalamus</fullName>
                            </names>
                            <xref>
                                <primaryRef db="intact" dbAc="MI:0469" id="IA:2436" refType="identity" refTypeAc="MI:0356"/>
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                            </xref>
                        </tissue>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Ruan H.B., Dietrich M.O., Liu Z.W., Zimmer M.R., Li M.D., Singh J.P., Zhang K., Yin R., Wu J., Horvath T.L., Yang X.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">tamas.horvath@yale.edu, xiaoyong.yang@yale.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">Cell (0092-8674)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2014</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1767023">
                <names>
                    <shortLabel>kcnq3_mouse</shortLabel>
                    <fullName>Potassium voltage-gated channel subfamily KQT member 3</fullName>
                    <alias typeAc="MI:0301" type="gene name">Kcnq3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">KQT-like 3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Potassium channel subunit alpha KvLQT3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Voltage-gated potassium channel subunit Kv7.3</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q8K3F6" version="SP_96" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060081" secondary="membrane hyperpolarization" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0036477" secondary="somatodendritic compartment" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005251" secondary="delayed rectifier potassium channel activity" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_145"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003948" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033268" secondary="node of Ranvier" version="SP_145"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003937" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031625" secondary="ubiquitin protein ligase binding" version="SP_145"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005821" version="SP_145"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-1296072" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005516" secondary="calmodulin binding" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_145"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013821" version="SP_145"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_690887.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030425" secondary="dendrite" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044325" secondary="transmembrane transporter binding" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005244" secondary="voltage-gated ion channel activity" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005249" secondary="voltage-gated potassium channel activity" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071242" secondary="cellular response to ammonium ion" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043194" secondary="axon initial segment" version="SP_145"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043025" secondary="neuronal cell body" version="SP_145"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000056258" version="SP_145" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005267" secondary="potassium channel activity" version="SP_145"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_145"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045121" secondary="membrane raft" version="SP_145"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071805" secondary="potassium ion transmembrane transport" version="SP_145"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MGLKARRAAGAAGGGGGEGGGGGGGAANPAGGDSAVAGDEERKVGLAPGDVEQVTLALGAGADKDGTLLLEGGGREEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEMDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRLDLVATWRFYESVVSFPFFRKEQLEAAASQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFLIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTYPSQQSPRNEPYVARAATSETEDQSMMGKFVKVERQVHDMGKKLDFLVDMHMQHMERLQVHVTEYYPTKGASSPAEGEKKEDNRYSDLKTIICNYSETGPPDPPYSFHQVPIDRVGPYGFFAHDPVKLTRGGPSSTKAQANLPSSGSTYAERPTVLPILTLLDSCVSYHSQTELQGPYSDHISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPSGGSSWMREKRYLAEGETDTDTDPFTPSGSMPMSSTGDGISDSIWTPSNKPT</sequence>
            </interactor>
            <interactor id="1767024">
                <names>
                    <shortLabel>ogt1_mouse</shortLabel>
                    <fullName>UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit</fullName>
                    <alias typeAc="MI:0301" type="gene name">Ogt</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">O-linked N-acetylglucosamine transferase 110 kDa subunit</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">O-GlcNAc transferase subunit p110</alias>
                </names>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-5675482" version="SP_158"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-3214847" version="SP_158"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-5689603" version="SP_158"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061087" secondary="positive regulation of histone H3-K27 methylation" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_158"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005547" secondary="phosphatidylinositol-3,4,5-trisphosphate binding" version="SP_158"/>
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                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10090">
                    <names>
                        <shortLabel>mouse</shortLabel>
                        <fullName>Mus musculus</fullName>
                        <alias typeAc="MI:1041" type="synonym">Mouse</alias>
                    </names>
                </organism>
                <sequence>MASSVGNVADSTEPTKRMLSFQGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVAEQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNLCLDKINVLHKPPYEHPKDLKLSDGRLRVGYVSSDFGNHPTSHLMQSIPGMHNPDKFEVFCYALSPDDGTNFRVKVMAEANHFIDLSQIPCNGKAADRIHQDGIHILVNMNGYTKGARNELFALRPAPIQAMWLGYPGTSGALFMDYIITDQETSPAEVAEQYSEKLAYMPHTFFIGDHANMFPHLKKKAVIDFKSNGHIYDNRIVLNGIDLKAFLDSLPDVKIVKMKCPDGGDNPDSSNTALNMPVIPMNTIAEAVIEMINRGQIQITINGFSISNGLATTQINNKAATGEEVPRTIIVTTRSQYGLPEDAIVYCNFNQLYKIDPSTLQMWANILKRVPNSVLWLLRFPAVGEPNIQQYAQNMGLPQNRIIFSPVAPKEEHVRRGQLADVCLDTPLCNGHTTGMDVLWAGTPMVTMPGETLASRVAASQLTCLGCLELIAKSRQEYEDIAVKLGTDLEYLKKIRGKVWKQRISSPLFNTKQYTMELERLYLQMWEHYAAGNKPDHMIKPVEVTESA</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-23619-1" id="1767025">
                <names>
                    <shortLabel>kcnq3-ogt</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-10044375" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-23619-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1767022</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1767026">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10044406" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1767023</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1767027">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-10044405" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1767024</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Fig. 4C</attribute>
                    <attribute name="agonist" nameAc="MI:0625">Fasting</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
