Molecular Connections Molecular Connections Pvt. Ltd. 2/2, Kariappa Road, Basavanagudi, Bangalore -560 004 www.molecularconnections.com www.molecularconnections.com zhang-2014-1 MicroRNA-566 activates EGFR signaling and its inhibition sensitizes glioblastoma cells to nimotuzumab. human-u87 Human U-87 MG glioblastoma cell line u87 anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhang K.L., Zhou X., Han L., Chen L.Y., Chen L.C., Shi Z.D., Yang M., Ren Y., Yang J.X., Frank T.S., Zhang C.B., Zhang J.X., Pu P.Y., Zhang J.N., Jiang T., Wagner E.J., Li M., Kang C.S., Zhang K.L., Zhou X., Han L., Chen L.Y., Chen L.C., Shi Z.D., Yang M., Ren Y., Yang J.X., Frank T.S., Zhang C.B., Zhang J.X., Pu P.Y., Zhang J.N., Jiang T., Wagner E.J., Li M., Kang C.S. Cancer - Interactions investigated in the context of cancer Eric.J.Wa gner@uth.tmc.edu Eric.J.Wagner@uth.tmc.edu Mol. Cancer 2014 Only protein-protein interactions imex curation Molecular Connections Pvt Ltd. zhang-2014-2 MicroRNA-566 activates EGFR signaling and its inhibition sensitizes glioblastoma cells to nimotuzumab. human-ln_229 Homo sapiens malignant glioma cell line LN-229 ln_229 Human malignant glioma cell line LN-229 anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zhang K.L., Zhou X., Han L., Chen L.Y., Chen L.C., Shi Z.D., Yang M., Ren Y., Yang J.X., Frank T.S., Zhang C.B., Zhang J.X., Pu P.Y., Zhang J.N., Jiang T., Wagner E.J., Li M., Kang C.S., Zhang K.L., Zhou X., Han L., Chen L.Y., Chen L.C., Shi Z.D., Yang M., Ren Y., Yang J.X., Frank T.S., Zhang C.B., Zhang J.X., Pu P.Y., Zhang J.N., Jiang T., Wagner E.J., Li M., Kang C.S. Cancer - Interactions investigated in the context of cancer Eric.J.Wa gner@uth.tmc.edu Eric.J.Wagner@uth.tmc.edu Mol. Cancer 2014 Only protein-protein interactions imex curation Molecular Connections Pvt Ltd. ctnb1_human Catenin beta-1 Beta-catenin OK/SW-cl.35 PRO2286 CTNNB1 CTNNB protein protein human Homo sapiens Human MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL hif1a_human Hypoxia-inducible factor 1-alpha ARNT-interacting protein Member of PAS protein 1 Basic-helix-loop-helix-PAS protein MOP1 HIF1A MOP1 BHLHE78 PASD8 PAS domain-containing protein 8 Class E basic helix-loop-helix protein 78 protein protein human Homo sapiens Human MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDAGDLDIEDDMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGRTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECVLKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYNDVMLPSPNEKLQNINLAMSPLPTAETPKPLRSSADPALNQEVALKLEPNPESLELSFTMPQIQDQTPSPSDGSTRQSSPEPNSPSEYCFYVDSDMVNEFKLELVEKLFAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPESASPQSTVTVFQQTQIQEPTANATTTTATTDELKTVTKDRMEDIKILIASPSPTHIHKETTSATSSPYRDTQSRTASPNRAGKGVIEQTEKSHPRSPNVLSVALSQRTTVPEEELNPKILALQNAQRKRKMEHDGSLFQAVGIGTLLQQPDDHAATTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN ctnnb1-hif1a-3 1530931 n/a 1530933 unspecified role unspecified role bait bait physiological level physiological level endogenous level endogenous endogenous endogenous level n/a 1530934 unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association false false false 5a lenti-AS-566 (a miR-566 inhibitor) ctnnb1-hif1a-1 1530931 n/a 1530934 unspecified role unspecified role bait bait physiological level physiological level endogenous level endogenous endogenous endogenous level n/a 1530933 unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association false false false 5a lenti-AS-566 (a miR-566 inhibitor) ctnnb1-hif1a-4 1530932 n/a 1530933 unspecified role unspecified role bait bait physiological level physiological level endogenous level endogenous endogenous endogenous level n/a 1530934 unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association false false false 5a lenti-AS-566 (a miR-566 inhibitor) ctnnb1-hif1a-5 1530932 n/a 1530934 unspecified role unspecified role bait bait physiological level physiological level endogenous level endogenous endogenous endogenous level n/a 1530933 unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level physical association physical association false false false 5a lenti-AS-566 (a miR-566 inhibitor)