UniProt UniProt http://www.uniprot.org maroui-2011-2 Promyelocytic leukemia isoform IV confers resistance to encephalomyocarditis virus via the sequestration of 3D polymerase in nuclear bodies. human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Maroui M.A., Pampin M., Chelbi-Alix M.K. mounira.chelbi-alix@parisdescartes.fr J. Virol. (0022-538X) 2011 Only protein-protein interactions imex curation maroui-2011-1 Promyelocytic leukemia isoform IV confers resistance to encephalomyocarditis virus via the sequestration of 3D polymerase in nuclear bodies. human-u373_mg Human glioblastoma astrocytoma u373_mg Human glioblastoma astrocytoma confocal microscopy confocal microscopy immunostaining immunostaining Maroui M.A., Pampin M., Chelbi-Alix M.K. mounira.chelbi-alix@parisdescartes.fr J. Virol. (0022-538X) 2011 Only protein-protein interactions imex curation p29590-5 Protein PML PML MYL RNF71 TRIM19 RING finger protein 71 Tripartite motif-containing protein 19 PML-IV PML-X TRIM19zeta Promyelocytic leukemia protein PP8675 E3 SUMO-protein ligase PML RING-type E3 SUMO transferase PML protein protein human Homo sapiens Human MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNESGFSWGYPHPFLI p03304-pro_0000039791 RNA-directed RNA polymerase protein protein emcv Encephalomyocarditis virus GALERLPDGPRIHVPRKTALRPTVARQVFQPAYAPAVLSKFDPRTEADVDEVAFSKHTSNQESLPPVFRMVAKEYANRVFTLLGKDNGRLTVKQALEGLEGMDPMDRNTSPGLPYTALGMRRTDVVDWESATLIPFAAERLRKMNEGDFSEVVYQTFLKDELRPIEKVQAAKTRIVDVPPFEHCILGRQLLGKFASKFQTQPGLELGSAIGCDPDVHWTAFGVAMQGFERVYDVDYSNFDSTHSVAMFRLLAEEFFTPENGFDPLTREYLESLAISTHAFEEKRFLITGGLPSGCAATSMLNTIMNNIIIRAGLYLTYKNFEFDDVKVLSYGDDLLVATNYQLDFDKVRASLAKTGYKITPANTTSTFPLNSTLEDVVFLKRKFKKEGPLYRPVMNREALEAMLSYYRPGTLSEKLTSITMLAVHSGKQEYDRLFAPFREVGVVVPSFESVEYRWRSLFW 1831 2290 pml-p03304_pro 1391895 n/a 1391897 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection n/a 1391898 unspecified role unspecified role prey prey nucl transfection nucleic acid transfection nucl transfection physical association physical association false false false 5C p03304_pro-pml-1 1391895 n/a 1391898 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection n/a 1391897 unspecified role unspecified role prey prey nucl transfection nucleic acid transfection nucl transfection c-terminal required to bind necessary binding region required to bind mutation analysis mutation analysis certain certain sequence position certain less-than less-than false physical association physical association false false false 5C and 6C p03304_pro-pml 1391896 n/a 1391897 unspecified role unspecified role neutral component neutral component nucl transfection nucleic acid transfection nucl transfection P29590-5:p.[Lys65Ala;Lys160Ala;Lys490Ala] mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false certain certain sequence position certain certain certain sequence position certain false c-terminal required to bind necessary binding region required to bind mutation analysis mutation analysis certain certain sequence position certain less-than less-than false n/a 1391898 unspecified role unspecified role neutral component neutral component nucl transfection nucleic acid transfection nucl transfection colocalization colocalization false false false 5A and B, 6B