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        <source releaseDate="2013-09-02+01:00">
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                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
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                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
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            <experimentDescription id="1323161">
                <names>
                    <shortLabel>aoyama-2012-1</shortLabel>
                    <fullName>CCN2/CTGF binds to fibroblast growth factor receptor 2 and modulates its signaling.</fullName>
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                        <fullName>protein array</fullName>
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                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Aoyama E., Kubota S., Takigawa M.</attribute>
                    <attribute name="journal" nameAc="MI:0885">FEBS Lett. (0014-5793)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2012</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
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            <interactor id="1323162">
                <names>
                    <shortLabel>cep43_human</shortLabel>
                    <fullName>Centrosomal protein 43</fullName>
                    <alias typeAc="MI:0301" type="gene name">CEP43</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FGFR1 oncogene partner</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FGFR1OP</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">FOP</alias>
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                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
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                <sequence>MAATAAAVVAEEDTELRDLLVQTLENSGVLNRIKAELRAAVFLALEEQEKVENKTPLVNESLKKFLNTKDGRLVASLVAEFLQFFNLDFTLAVFQPETSTLQGLEGRENLARDLGIIEAEGTVGGPLLLEVIRRCQQKEKGPTTGEGALDLSDVHSPPKSPEGKTSAQTTPSKIPRYKGQGKKKTSGQKAGDKKANDEANQSDTSVSLSEPKSKSSLHLLSHETKIGSFLSNRTLDGKDKAGLCPDEDDMEGDSFFDDPIPKPEKTYGLRKEPRKQAGSLASLSDAPPLKSGLSSLAGAPSLKDSESKRGNTVLKDLKLISDKIGSLGLGTGEDDDYVDDFNSTSHRSEKSEISIGEEIEEDLSVEIDDINTSDKLDDLTQDLTVSQLSDVADYLEDVA</sequence>
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                    <shortLabel>ccn2_human</shortLabel>
                    <fullName>CCN family member 2</fullName>
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                    <alias typeAc="MI:0302" type="gene name synonym">CTGF</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Cellular communication network factor 2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Connective tissue growth factor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">HCS24</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Hypertrophic chondrocyte-specific protein 24</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">IGFBP8</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Insulin-like growth factor-binding protein 8</alias>
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                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
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                </organism>
                <sequence>MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCHFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA</sequence>
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                    <shortLabel>fgfr2_human</shortLabel>
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                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q1KHY5" version="SP_128" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UQI0" version="SP_110" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035603" secondary="fibroblast growth factor receptor signaling pathway involved in hemopoiesis" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001657" secondary="ureteric bud development" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060501" secondary="positive regulation of epithelial cell proliferation involved in lung morphogenesis" version="SP_261"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2PY3" version="SP_261"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5655253" version="SP_261"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008266" version="SP_261"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UQH7" version="SP_110" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3CAF" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051781" secondary="positive regulation of cell division" version="SP_261"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2PVY" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048730" secondary="epidermis morphogenesis" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_261"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4WV1" version="SP_261"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14300" version="SP_110" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6AGX" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060915" secondary="mesenchymal cell differentiation involved in lung development" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048286" secondary="lung alveolus development" version="SP_261"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001138387.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3CU1" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_261"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1WVZ" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003149" secondary="membranous septum morphogenesis" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030324" secondary="lung development" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030177" secondary="positive regulation of Wnt signaling pathway" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060174" secondary="limb bud formation" version="SP_261"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1DJS" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060449" secondary="bud elongation involved in lung branching" version="SP_261"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-190375" version="SP_261"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001307587.1"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2023837" version="SP_261"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000351276" version="SP_261" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007409" secondary="axonogenesis" version="SP_261"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8853333" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070372" secondary="regulation of ERK1 and ERK2 cascade" version="SP_261"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UIH5" version="SP_110" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001138388.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060442" secondary="branching involved in prostate gland morphogenesis" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060484" secondary="lung-associated mesenchyme development" version="SP_261"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2PWL" version="SP_261"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4J97" version="SP_261"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000132.3"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_075259.4"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="E7EVR6" version="SP_163" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5654700" version="SP_261"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8851708" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005007" secondary="fibroblast growth factor-activated receptor activity" version="SP_261"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060595" secondary="fibroblast growth factor receptor signaling pathway involved in mammary gland specification" version="SP_261"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT</sequence>
            </interactor>
            <interactor id="1323165">
                <names>
                    <shortLabel>fgfr3_human</shortLabel>
                    <fullName>Fibroblast growth factor receptor 3</fullName>
                    <alias typeAc="MI:0301" type="gene name">FGFR3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">JTK4</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P22607" version="SP_110" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0017134" secondary="fibroblast growth factor binding" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5654706" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" secondary="Golgi apparatus" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5654227" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8853338" version="SP_251"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000414914" version="SP_251" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001501" secondary="skeletal system development" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0018108" secondary="peptidyl-tyrosine phosphorylation" version="SP_251"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013098" version="SP_251"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LZL" version="SP_251"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036179" version="SP_251"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000440486" version="SP_251" refType="transcript"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q59FL9" version="SP_154" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043410" secondary="positive regulation of MAPK cascade" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2219530" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005783" secondary="endoplasmic reticulum" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007267" secondary="cell-cell signaling" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002062" secondary="chondrocyte differentiation" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-109704" version="SP_251"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_075254.1"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D3DVP9" version="SP_151" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004713" secondary="protein tyrosine kinase activity" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5654704" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048640" secondary="negative regulation of developmental growth" version="SP_251"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-348399" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010518" secondary="positive regulation of phospholipase activity" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003416" secondary="endochondral bone growth" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6811558" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042531" secondary="positive regulation of tyrosine phosphorylation of STAT protein" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035988" secondary="chondrocyte proliferation" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043235" secondary="receptor complex" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060349" secondary="bone morphogenesis" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007169" secondary="transmembrane receptor protein tyrosine kinase signaling pathway" version="SP_251"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001245" version="SP_251"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR041159" version="SP_251"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6PNX" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070374" secondary="positive regulation of ERK1 and ERK2 cascade" version="SP_251"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001156685.1"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-190371" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030282" secondary="bone mineralization" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033674" secondary="positive regulation of kinase activity" version="SP_251"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020635" version="SP_251"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR007110" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030133" secondary="transport vesicle" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5673001" version="SP_251"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4K33" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-190372" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5654710" version="SP_251"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6LVM" version="SP_251"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011009" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2033514" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902178" secondary="fibroblast growth factor receptor apoptotic signaling pathway" version="SP_251"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-4016N"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7DHL" version="SP_251"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008266" version="SP_251"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D3DVQ0" version="SP_151" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000133.1"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1RY7" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005007" secondary="fibroblast growth factor-activated receptor activity" version="SP_251"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016248" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000165" secondary="MAPK cascade" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1839130" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008284" secondary="positive regulation of cell population proliferation" version="SP_251"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q16608" version="SP_110" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013783" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008543" secondary="fibroblast growth factor receptor signaling pathway" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_251"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000068078" version="SP_251" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043552" secondary="positive regulation of phosphatidylinositol 3-kinase activity" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070977" secondary="bone maturation" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8853334" version="SP_251"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000719" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004714" secondary="transmembrane receptor protein tyrosine kinase activity" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1257604" version="SP_251"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003598" version="SP_251"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q14308" version="SP_110" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" secondary="extracellular region" version="SP_251"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017441" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046777" secondary="protein autophosphorylation" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5654732" version="SP_251"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001958" secondary="endochondral ossification" version="SP_251"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003599" version="SP_251"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q16294" version="SP_110" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_251"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2033515" version="SP_251"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MGAPACALALCVAVAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSGGSRT</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="1323166">
                <names>
                    <shortLabel>fgfr1op-ctgf</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8400171" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8157592" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1323161</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1323167">
                        <names>
                            <shortLabel>fgfr1 oncogene partn</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">FGFR1OP</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8400174" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8157600" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1323162</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>predetermined</shortLabel>
                                    <fullName>predetermined participant</fullName>
                                    <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1323168">
                        <names>
                            <shortLabel>ctgf_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">CCN2</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8400173" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8157597" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1323163</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>elisa</shortLabel>
                                    <fullName>enzyme linked immunosorbent assay</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">ELISA</alias>
                                    <alias typeAc="MI:1041" type="synonym">ELISA</alias>
                                    <alias typeAc="MI:1041" type="synonym">elisa</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0411" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608792" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="11906746" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <featureList>
                            <feature id="1323169">
                                <names>
                                    <shortLabel>his tag</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8400176" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8157603" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>his tag</shortLabel>
                                        <fullName>his tag</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">Hexa-His-tag</alias>
                                        <alias typeAc="MI:0303" type="go synonym">6-His-tag</alias>
                                        <alias typeAc="MI:0303" type="go synonym">Histidine-tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">Hexa-His-tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">Histidine-tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">6-His-tag</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0521" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456516" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f1</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction id="1323170">
                <names>
                    <shortLabel>fgfr2-ctgf</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8400183" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8157633" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1323161</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1323171">
                        <names>
                            <shortLabel>fgfr2_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">FGFR2</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8400185" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8157641" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1323164</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>predetermined</shortLabel>
                                    <fullName>predetermined participant</fullName>
                                    <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1323172">
                        <names>
                            <shortLabel>ctgf_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">CCN2</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8400187" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8157638" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1323163</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>elisa</shortLabel>
                                    <fullName>enzyme linked immunosorbent assay</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">ELISA</alias>
                                    <alias typeAc="MI:1041" type="synonym">ELISA</alias>
                                    <alias typeAc="MI:1041" type="synonym">elisa</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0411" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608792" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="11906746" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <featureList>
                            <feature id="1323173">
                                <names>
                                    <shortLabel>his tag</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8400188" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8157644" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>his tag</shortLabel>
                                        <fullName>his tag</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">Hexa-His-tag</alias>
                                        <alias typeAc="MI:0303" type="go synonym">6-His-tag</alias>
                                        <alias typeAc="MI:0303" type="go synonym">Histidine-tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">Hexa-His-tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">Histidine-tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">6-His-tag</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0521" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456516" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f1</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction id="1323174">
                <names>
                    <shortLabel>fgfr3-ctgf</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8400193" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8157674" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1323161</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1323175">
                        <names>
                            <shortLabel>fgfr3_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">FGFR3</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8400195" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8157682" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1323165</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>predetermined</shortLabel>
                                    <fullName>predetermined participant</fullName>
                                    <alias typeAc="MI:1041" type="synonym">predetermined</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1323176">
                        <names>
                            <shortLabel>ctgf_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">CCN2</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8400197" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8157679" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1323163</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>elisa</shortLabel>
                                    <fullName>enzyme linked immunosorbent assay</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">ELISA</alias>
                                    <alias typeAc="MI:1041" type="synonym">ELISA</alias>
                                    <alias typeAc="MI:1041" type="synonym">elisa</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0411" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608792" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="11906746" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>purified</shortLabel>
                                    <fullName>purified</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <featureList>
                            <feature id="1323177">
                                <names>
                                    <shortLabel>his tag</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8400198" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8157685" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>his tag</shortLabel>
                                        <fullName>his tag</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">Hexa-His-tag</alias>
                                        <alias typeAc="MI:0303" type="go synonym">6-His-tag</alias>
                                        <alias typeAc="MI:0303" type="go synonym">Histidine-tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">Hexa-His-tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">Histidine-tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">6-His-tag</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0521" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456516" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f1</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
