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                    <shortLabel>kaul-2012-1</shortLabel>
                    <fullName>Five dysfunctional telomeres predict onset of senescence in human cells.</fullName>
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                    <attribute name="author-list" nameAc="MI:0636">Kaul Z., Cesare AJ., Huschtscha LI., Neumann AA., Reddel RR.</attribute>
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                    <attribute name="publication year" nameAc="MI:0886">2012</attribute>
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                    <shortLabel>kaul-2012-2</shortLabel>
                    <fullName>Five dysfunctional telomeres predict onset of senescence in human cells.</fullName>
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                        <fullName>Homo sapiens</fullName>
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                <sequence>MSGRGKTGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGHYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTSATVGPKAPSGGKKATQASQEY</sequence>
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                    <fullName>Nibrin</fullName>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008283" secondary="cell population proliferation" version="SP_188"/>
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                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q32NF7" version="SP_53" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693579" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_188"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032429" version="SP_188"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69473" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_188"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5685942" version="SP_188"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-33605N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000781" secondary="chromosome, telomeric region" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003684" secondary="damaged DNA binding" version="SP_188"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000104320" version="SP_188" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051321" secondary="meiotic cell cycle" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031860" secondary="telomeric 3' overhang formation" version="SP_188"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693565" version="SP_188"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001019859.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016592" version="SP_188"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000265433" version="SP_188" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036420" version="SP_188"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-494844" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0140297" secondary="DNA-binding transcription factor binding" version="SP_188"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_002476.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090656" secondary="t-circle formation" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000724" secondary="double-strand break repair via homologous recombination" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030330" secondary="DNA damage response, signal transduction by p53 class mediator" version="SP_188"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR040227" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042405" secondary="nuclear inclusion body" version="SP_188"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000253" version="SP_188"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693568" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006302" secondary="double-strand break repair" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032508" secondary="DNA duplex unwinding" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0047485" secondary="protein N-terminus binding" version="SP_188"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2559586" version="SP_188"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5WQD" version="SP_188"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR043014" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000077" secondary="DNA damage checkpoint signaling" version="SP_188"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693607" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032206" secondary="positive regulation of telomere maintenance" version="SP_188"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5685938" version="SP_188"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53FM6" version="SP_53" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045190" secondary="isotype switching" version="SP_188"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B2RNC5" version="SP_78" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693616" version="SP_188"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5685939" version="SP_188"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q63HR6" version="SP_53" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013908" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_188"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008984" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031954" secondary="positive regulation of protein autophosphorylation" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050885" secondary="neuromuscular process controlling balance" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033674" secondary="positive regulation of kinase activity" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001832" secondary="blastocyst growth" version="SP_188"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="O60934" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016605" secondary="PML body" version="SP_188"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-912446" version="SP_188"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O60672" version="SP_53" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000723" secondary="telomere maintenance" version="SP_188"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035861" secondary="site of double-strand break" version="SP_188"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000265433" version="SP_188" refType="transcript"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MWKLLPAAGPAGGEPYRLLTGVEYVVGRKNCAILIENDQSISRNHAVLTANFSVTNLSQTDEIPVLTLKDNSKYGTFVNEEKMQNGFSRTLKSGDGITFGVFGSKFRIEYEPLVACSSCLDVSGKTALNQAILQLGGFTVNNWTEECTHLVMVSVKVTIKTICALICGRPIVKPEYFTEFLKAVESKKQPPQIESFYPPLDEPSIGSKNVDLSGRQERKQIFKGKTFIFLNAKQHKKLSSAVVFGGGEARLITEENEEEHNFFLAPGTCVVDTGITNSQTLIPDCQKKWIQSIMDMLQRQGLRPIPEAEIGLAVIFMTTKNYCDPQGHPSTGLKTTTPGPSLSQGVSVDEKLMPSAPVNTTTYVADTESEQADTWDLSERPKEIKVSKMEQKFRMLSQDAPTVKESCKTSSNNNSMVSNTLAKMRIPNYQLSPTKLPSINKSKDRASQQQQTNSIRNYFQPSTKKRERDEENQEMSSCKSARIETSCSLLEQTQPATPSLWKNKEQHLSENEPVDTNSDNNLFTDTDLKSIVKNSASKSHAAEKLRSNKKREMDDVAIEDEVLEQLFKDTKPELEIDVKVQKQEEDVNVRKRPRMDIETNDTFSDEAVPESSKISQENEIGKKRELKEDSLWSAKEISNNDKLQDDSEMLPKKLLLTEFRSLVIKNSTSRNPSGINDDYGQLKNFKKFKKVTYPGAGKLPHIIGGSDLIAHHARKNTELEEWLRQEMEVQNQHAKEESLADDLFRYNPYLKRRR</sequence>
            </interactor>
            <interactor id="1253836">
                <names>
                    <shortLabel>mre11_human</shortLabel>
                    <fullName>Double-strand break repair protein MRE11</fullName>
                    <alias typeAc="MI:0301" type="gene name">MRE11</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Double-strand break repair protein MRE11A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">HNGS1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">MRE11A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Meiotic recombination 11 homolog 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Meiotic recombination 11 homolog A</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P49959" version="SP_82" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3270619" version="SP_223"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-33238N"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-396513" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008409" secondary="5'-3' exonuclease activity" version="SP_223"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029052" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000729" secondary="DNA double-strand break processing" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030870" secondary="Mre11 complex" version="SP_223"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_005582.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007129" secondary="homologous chromosome pairing at meiosis" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005657" secondary="replication fork" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693548" version="SP_223"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR007281" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693554" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693571" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6804756" version="SP_223"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000020922" version="SP_223" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006310" secondary="DNA recombination" version="SP_223"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000323929" version="SP_223" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007095" secondary="mitotic G2 DNA damage checkpoint signaling" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007004" secondary="telomere maintenance via telomerase" version="SP_223"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR041796" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008283" secondary="cell population proliferation" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045296" secondary="cadherin binding" version="SP_223"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004843" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000014" secondary="single-stranded DNA endodeoxyribonuclease activity" version="SP_223"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_005581.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1834949" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003690" secondary="double-stranded DNA binding" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_223"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3T1I" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5685942" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031860" secondary="telomeric 3' overhang formation" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693565" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000781" secondary="chromosome, telomeric region" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008022" secondary="protein C-terminus binding" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-69473" version="SP_223"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011541139.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006974" secondary="cellular response to DNA damage stimulus" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000724" secondary="double-strand break repair via homologous recombination" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031573" secondary="mitotic intra-S DNA damage checkpoint signaling" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006281" secondary="DNA repair" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035861" secondary="site of double-strand break" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0110025" secondary="DNA strand resection involved in replication fork processing" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030145" secondary="manganese ion binding" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007062" secondary="sister chromatid cohesion" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032508" secondary="DNA duplex unwinding" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006302" secondary="double-strand break repair" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007131" secondary="reciprocal meiotic recombination" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042138" secondary="meiotic DNA double-strand break formation" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006303" secondary="double-strand break repair via nonhomologous end joining" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032206" secondary="positive regulation of telomere maintenance" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693607" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2559586" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5685938" version="SP_223"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000325863" version="SP_223" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O43475" version="SP_82" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004518" secondary="nuclease activity" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5685939" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693579" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097552" secondary="mitochondrial double-strand break repair via homologous recombination" version="SP_223"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR038487" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693616" version="SP_223"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016873261.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008408" secondary="3'-5' exonuclease activity" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004520" secondary="endodeoxyribonuclease activity" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033674" secondary="positive regulation of kinase activity" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031954" secondary="positive regulation of protein autophosphorylation" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000019" secondary="regulation of mitotic recombination" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-912446" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016605" secondary="PML body" version="SP_223"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003701" version="SP_223"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B3KTC7" version="SP_160" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000723" secondary="telomere maintenance" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008296" secondary="3'-5'-exodeoxyribonuclease activity" version="SP_223"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_223"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5693568" version="SP_223"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P49959" version="SP_223"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MSTADALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGDLFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISIPVFSIHGNHDDPTGADALCALDILSCAGFVNHFGRSMSVEKIDISPVLLQKGSTKIALYGLGSIPDERLYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRSKHGSTNFIPEQFLDDFIDLVIWGHEHECKIAPTKNEQQLFYISQPGSSVVTSLSPGEAVKKHVGLLRIKGRKMNMHKIPLHTVRQFFMEDIVLANHPDIFNPDNPKVTQAIQSFCLEKIEEMLENAERERLGNSHQPEKPLVRLRVDYSGGFEPFSVLRFSQKFVDRVANPKDIIHFFRHREQKEKTGEEINFGKLITKPSEGTTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEKTQRFLKERHIDALEDKIDEEVRRFRETRQKNTNEEDDEVREAMTRARALRSQSEESASAFSADDLMSIDLAEQMANDSDDSISAATNKGRGRGRGRRGGRGQNSASRGGSQRGRADTGLETSTRSRNSKTAVSASRNMSIIDAFKSTRQQPSRNVTTKNYSEVIEVDESDVEEDIFPTTSKTDQRWSSTSSSKIMSQSQVSKGVDFESSEDDDDDPFMNTSSLRRNRR</sequence>
            </interactor>
            <interactor id="1253837">
                <names>
                    <shortLabel>te2ip_human</shortLabel>
                    <fullName>Telomeric repeat-binding factor 2-interacting protein 1</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">DRIP5</alias>
                    <alias typeAc="MI:0301" type="gene name">TERF2IP</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">RAP1</alias>
                    <alias typeAc="MI:0306" type="orf name">PP8000</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Dopamine receptor-interacting protein 5</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Repressor/activator protein 1 homolog</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NYB0" version="SP_70" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-110331" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007004" secondary="telomere maintenance via telomerase" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006355" secondary="regulation of transcription, DNA-templated" version="SP_199"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001357" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048239" secondary="negative regulation of DNA recombination at telomere" version="SP_199"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9670095" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070198" secondary="protein localization to chromosome, telomeric region" version="SP_199"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000166848" version="SP_199" refType="gene"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000300086" version="SP_199" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070187" secondary="shelterin complex" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_199"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR039595" version="SP_199"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q9NYB0" version="SP_199"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1221632" version="SP_199"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8WYZ3" version="SP_70" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1FEX" version="SP_199"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2559586" version="SP_199"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-174411" version="SP_199"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-174437" version="SP_199"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-110329" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010833" secondary="telomere maintenance via telomere lengthening" version="SP_199"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-174430" version="SP_199"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-750109" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031848" secondary="protection from non-homologous end joining at telomere" version="SP_199"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-171319" version="SP_199"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4DQN4" version="SP_106" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9NWR2" version="SP_70" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098505" secondary="G-rich strand telomeric DNA binding" version="SP_199"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-171306" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019902" secondary="phosphatase binding" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000783" secondary="nuclear telomere cap complex" version="SP_199"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-174414" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000781" secondary="chromosome, telomeric region" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032205" secondary="negative regulation of telomere maintenance" version="SP_199"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3K6G" version="SP_199"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000300086" version="SP_199" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q4W4Y2" version="SP_106" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000228" secondary="nuclear chromosome" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033138" secondary="positive regulation of peptidyl-serine phosphorylation" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" secondary="positive regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051092" secondary="positive regulation of NF-kappaB transcription factor activity" version="SP_199"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4RQI" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901985" secondary="positive regulation of protein acetylation" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000723" secondary="telomere maintenance" version="SP_199"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_061848.2"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-110328" version="SP_199"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036420" version="SP_199"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015010" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042162" secondary="telomeric DNA binding" version="SP_199"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-174417" version="SP_199"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009057" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001933" secondary="negative regulation of protein phosphorylation" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901224" secondary="positive regulation of NIK/NF-kappaB signaling" version="SP_199"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR038104" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032204" secondary="regulation of telomere maintenance" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016604" secondary="nuclear body" version="SP_199"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010569" secondary="regulation of double-strand break repair via homologous recombination" version="SP_199"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR021661" version="SP_199"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-34868N"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-110330" version="SP_199"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MAEAMDLGKDPNGPTHSSTLFVRDDGSSMSFYVRPSPAKRRLSTLILHGGGTVCRVQEPGAVLLAQPGEALAEASGDFISTQYILDCVERNERLELEAYRLGPASAADTGSEAKPGALAEGAAEPEPQRHAGRIAFTDADDVAILTYVKENARSPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPEVGAAIKIIRQLMEKFNLDLSTVTQAFLKNSGELEATSAFLASGQRADGYPIWSRQDDIDLQKDDEDTREALVKKFGAQNVARRIEFRKK</sequence>
            </interactor>
            <interactor id="1253838">
                <names>
                    <shortLabel>terf2_human</shortLabel>
                    <fullName>Telomeric repeat-binding factor 2</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">TTAGGG repeat-binding factor 2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Telomeric DNA-binding protein</alias>
                    <alias typeAc="MI:0301" type="gene name">TERF2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">TRF2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">TRBF2</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q15554" version="SP_76" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-110328" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" secondary="protein-containing complex binding" version="SP_216"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3BUA" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098505" secondary="G-rich strand telomeric DNA binding" version="SP_216"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000132604" version="SP_216" refType="gene"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017357" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008022" secondary="protein C-terminus binding" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032205" secondary="negative regulation of telomere maintenance" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000783" secondary="nuclear telomere cap complex" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904357" secondary="negative regulation of telomere maintenance via telomere lengthening" version="SP_216"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1H6P" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032208" secondary="negative regulation of telomere maintenance via recombination" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001701" secondary="in utero embryonic development" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000781" secondary="chromosome, telomeric region" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000723" secondary="telomere maintenance" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904115" secondary="axon cytoplasm" version="SP_216"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3K6G" version="SP_216"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-174414" version="SP_216"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="7C5D" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904430" secondary="negative regulation of t-circle formation" version="SP_216"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-34052N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0099087" secondary="anterograde axonal transport of messenger ribonucleoprotein complex" version="SP_216"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4RQI" version="SP_216"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5WQD" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070187" secondary="shelterin complex" version="SP_216"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000254942" version="SP_216" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032211" secondary="negative regulation of telomere maintenance via telomerase" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042162" secondary="telomeric DNA binding" version="SP_216"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_005643.2"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR030657" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061820" secondary="telomeric D-loop disassembly" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032206" secondary="positive regulation of telomere maintenance" version="SP_216"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-174417" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016604" secondary="nuclear body" version="SP_216"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5XYF" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032204" secondary="regulation of telomere maintenance" version="SP_216"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-110330" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051000" secondary="positive regulation of nitric-oxide synthase activity" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016233" secondary="telomere capping" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905839" secondary="negative regulation of telomeric D-loop disassembly" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904354" secondary="negative regulation of telomere capping" version="SP_216"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3BU8" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" secondary="protein homodimerization activity" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010629" secondary="negative regulation of gene expression" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031848" secondary="protection from non-homologous end joining at telomere" version="SP_216"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001005" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032214" secondary="negative regulation of telomere maintenance via semi-conservative replication" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905778" secondary="negative regulation of exonuclease activity" version="SP_216"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-110331" version="SP_216"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013867" version="SP_216"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9670095" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007049" secondary="cell cycle" version="SP_216"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-706651" refType="intact-secondary"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031627" secondary="telomeric loop formation" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000773" secondary="negative regulation of cellular senescence" version="SP_216"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1VF9" version="SP_216"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-706637" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032210" secondary="regulation of telomere maintenance via telomerase" version="SP_216"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR031902" version="SP_216"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009057" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003691" secondary="double-stranded telomeric DNA binding" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090398" secondary="cellular senescence" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903824" secondary="negative regulation of telomere single strand break repair" version="SP_216"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1XG1" version="SP_216"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3SJM" version="SP_216"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1W0U" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001673" secondary="male germ cell nucleus" version="SP_216"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q15554" version="SP_216"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000254942" version="SP_216" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070198" secondary="protein localization to chromosome, telomeric region" version="SP_216"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036507" version="SP_216"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1221632" version="SP_216"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017930" version="SP_216"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-174430" version="SP_216"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2559586" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019899" secondary="enzyme binding" version="SP_216"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-171306" version="SP_216"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-174411" version="SP_216"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-110329" version="SP_216"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-171319" version="SP_216"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-174437" version="SP_216"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1VFC" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903770" secondary="negative regulation of beta-galactosidase activity" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006278" secondary="RNA-dependent DNA biosynthetic process" version="SP_216"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_216"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4M7C" version="SP_216"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6J67" version="SP_216"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MAAGAGTAGPASGPGVVRDPAASQPRKRPGREGGEGARRSDTMAGGGGSSDGSGRAAGRRASRSSGRARRGRHEPGLGGPAERGAGEARLEEAVNRWVLKFYFHEALRAFRGSRYGDFRQIRDIMQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQNFSYETFQQKMLRFLESHLDDAEPYLLTMAKKALKSESAASSTGKEDKQPAPGPVEKPPREPARQLRNPPTTIGMMTLKAAFKTLSGAQDSEAAFAKLDQKDLVLPTQALPASPALKNKRPRKDENESSAPADGEGGSELQPKNKRMTISRLVLEEDSQSTEPSAGLNSSQEAASAPPSKPTVLNQPLPGEKNPKVPKGKWNSSNGVEEKETWVEEDELFQVQAAPDEDSTTNITKKQKWTVEESEWVKAGVQKYGEGNWAAISKNYPFVNRTAVMIKDRWRTMKRLGMN</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-16516-3" id="1253839">
                <names>
                    <shortLabel>h2afx-nbn</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8303392" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7603324" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-16516-3" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035985" refType="go-definition-ref" refTypeAc="MI:0242"/>
                </xref>
                <experimentList>
                    <experimentRef>1253832</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1253840">
                        <names>
                            <shortLabel>h2ax_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">H2AX</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8303394" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7603334" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1253834</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>immunostaining</shortLabel>
                                    <fullName>immunostaining</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>fixed cell</shortLabel>
                                    <fullName>fixed cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0348" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537839" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1253841">
                        <names>
                            <shortLabel>nbn_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">NBS1</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8303395" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7603331" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1253835</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>immunostaining</shortLabel>
                                    <fullName>immunostaining</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>fixed cell</shortLabel>
                                    <fullName>fixed cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0348" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537839" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f3a</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-16516-4" id="1253842">
                <names>
                    <shortLabel>h2afx-mre11a-3</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8303402" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-16516-4" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7603337" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035985" refType="go-definition-ref" refTypeAc="MI:0242"/>
                </xref>
                <experimentList>
                    <experimentRef>1253832</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1253843">
                        <names>
                            <shortLabel>h2ax_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">H2AX</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8303405" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7603347" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1253834</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>immunostaining</shortLabel>
                                    <fullName>immunostaining</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>fixed cell</shortLabel>
                                    <fullName>fixed cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0348" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537839" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1253844">
                        <names>
                            <shortLabel>mre11_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">MRE11</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8303407" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7603344" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1253836</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>immunostaining</shortLabel>
                                    <fullName>immunostaining</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>fixed cell</shortLabel>
                                    <fullName>fixed cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0348" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537839" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f3a</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-16516-1" id="1253845">
                <names>
                    <shortLabel>h2afx-terf2ip</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8303414" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000781" secondary="chromosome, telomeric region" refType="go-definition-ref" refTypeAc="MI:0242"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7603377" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-16516-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1253833</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1253846">
                        <names>
                            <shortLabel>h2ax_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">H2AX</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8303416" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7603384" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1253834</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>immunostaining</shortLabel>
                                    <fullName>immunostaining</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>subcellular prep</shortLabel>
                                    <fullName>subcellular preparation</fullName>
                                    <alias typeAc="MI:1041" type="synonym">subcellular prep</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0372" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537724" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1253847">
                        <names>
                            <shortLabel>te2ip_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">RAP1</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8303417" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7603387" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1253837</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>immunostaining</shortLabel>
                                    <fullName>immunostaining</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>subcellular prep</shortLabel>
                                    <fullName>subcellular preparation</fullName>
                                    <alias typeAc="MI:1041" type="synonym">subcellular prep</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0372" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537724" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f4d</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-16516-2" id="1253848">
                <names>
                    <shortLabel>h2afx-terf2-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8303424" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-16516-2" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7603410" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000781" secondary="chromosome, telomeric region" refType="go-definition-ref" refTypeAc="MI:0242"/>
                </xref>
                <experimentList>
                    <experimentRef>1253833</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1253849">
                        <names>
                            <shortLabel>h2ax_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">H2AX</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8303427" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7603420" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1253834</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>immunostaining</shortLabel>
                                    <fullName>immunostaining</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>subcellular prep</shortLabel>
                                    <fullName>subcellular preparation</fullName>
                                    <alias typeAc="MI:1041" type="synonym">subcellular prep</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0372" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537724" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1253850">
                        <names>
                            <shortLabel>terf2_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">TRF2</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8303429" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-7603417" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1253838</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>immunostaining</shortLabel>
                                    <fullName>immunostaining</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0422" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>subcellular prep</shortLabel>
                                    <fullName>subcellular preparation</fullName>
                                    <alias typeAc="MI:1041" type="synonym">subcellular prep</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0372" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537724" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">f4d</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
