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                    <fullName>Antagonistic regulation of EMT by TIF1γ and Smad4 in mammary epithelial cells.</fullName>
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                    <fullName>Antagonistic regulation of EMT by TIF1γ and Smad4 in mammary epithelial cells.</fullName>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5C4V" version="SP_235"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2173789" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071144" secondary="heteromeric SMAD protein complex" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007338" secondary="single fertilization" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0017015" secondary="regulation of transforming growth factor beta receptor signaling pathway" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030154" secondary="cell differentiation" version="SP_235"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MEY" version="SP_235"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3315487" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003220" secondary="left ventricular cardiac muscle tissue morphogenesis" version="SP_235"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1U7F" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060391" secondary="positive regulation of SMAD protein signal transduction" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043199" secondary="sulfate binding" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008283" secondary="cell population proliferation" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060548" secondary="negative regulation of cell death" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" secondary="response to hypoxia" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003161" secondary="cardiac conduction system development" version="SP_235"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000381452" version="SP_235" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046881" secondary="positive regulation of follicle-stimulating hormone secretion" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032525" secondary="somite rostral/caudal axis specification" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061629" secondary="RNA polymerase II-specific DNA-binding transcription factor binding" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070373" secondary="negative regulation of ERK1 and ERK2 cascade" version="SP_235"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9615017" version="SP_235"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5689880" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000976" secondary="transcription cis-regulatory region binding" version="SP_235"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" secondary="positive regulation of transcription, DNA-templated" version="SP_235"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YGS" version="SP_235"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MDNMSITNTPTSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLLQIASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGHYWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTMPIADPQPLD</sequence>
            </interactor>
            <interactor id="1169893">
                <names>
                    <shortLabel>tri33_human</shortLabel>
                    <fullName>E3 ubiquitin-protein ligase TRIM33</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">RING-type E3 ubiquitin transferase TRIM33</alias>
                    <alias typeAc="MI:0301" type="gene name">TRIM33</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">KIAA1113</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">RFG7</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">TIF1G</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Tripartite motif-containing protein 33</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Transcription intermediary factor 1-gamma</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Ectodermin homolog</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">RET-fused gene 7 protein</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UPN9" version="SP_86" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR019787" version="SP_204"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5TG72" version="SP_86" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011011" version="SP_204"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3U5M" version="SP_204"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-54262N"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003649" version="SP_204"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001487" version="SP_204"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5MR8" version="SP_204"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5TG73" version="SP_86" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9C017" version="SP_86" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3U5N" version="SP_204"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070412" secondary="R-SMAD binding" version="SP_204"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2214398" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036427" version="SP_204"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000197323" version="SP_204" refType="gene"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_056990.3"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016567" secondary="protein ubiquitination" version="SP_204"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5TG74" version="SP_86" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_204"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008270" secondary="zinc ion binding" version="SP_204"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004842" secondary="ubiquitin-protein transferase activity" version="SP_204"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3U5O" version="SP_204"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9UJ79" version="SP_86" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0017015" secondary="regulation of transforming growth factor beta receptor signaling pathway" version="SP_204"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000351250" version="SP_204" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" secondary="negative regulation of transcription, DNA-templated" version="SP_204"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2173795" version="SP_204"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_204"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070410" secondary="co-SMAD binding" version="SP_204"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3U5P" version="SP_204"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001965" version="SP_204"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000122" secondary="negative regulation of transcription by RNA polymerase II" version="SP_204"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR019786" version="SP_204"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030514" secondary="negative regulation of BMP signaling pathway" version="SP_204"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="Q9UPN9" version="SP_204"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_148980.2"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027370" version="SP_204"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000358465" version="SP_204" refType="transcript"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013083" version="SP_204"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O95855" version="SP_86" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017907" version="SP_204"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001841" version="SP_204"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" secondary="DNA binding" version="SP_204"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000315" version="SP_204"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MAENKGGGEAESGGGGSGSAPVTAGAAGPAAQEAEPPLTAVLVEEEEEEGGRAGAEGGAAGPDDGGVAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPEPERQLSVPIPGGSNGDIQQVGVIRCPVCRQECRQIDLVDNYFVKDTSEAPSSSDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLENVTKERQMKLLQQQNDITGLSRQVKHVMNFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIESKPAPGYTPNVVVGQVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPPAPVPTTTTTTQQHPRQAAPQMLQQQPPRLISVQTMQRGNMNCGAFQAHQMRLAQNAARIPGIPRHSGPQYSMMQPHLQRQHSNPGHAGPFPVVSVHNTTINPTSPTTATMANANRGPTSPSVTAIELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPSPGPSALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKTSLSFKSDQVKVKQEPGTEDEICSFSGGVKQEKTEDGRRSACMLSSPESSLTPPLSTNLHLESELDALASLENHVKIEPADMNESCKQSGLSSLVNGKSPIRSLMHRSARIGGDGNNKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKADSEVAQAGKAVALYFEDKLTEIYSDRTFAPLPEFEQEEDDGEVTEDSDEDFIQPRRKRLKSDERPVHIK</sequence>
            </interactor>
            <interactor id="1169894">
                <names>
                    <shortLabel>smad3_human</shortLabel>
                    <fullName>Mothers against decapentaplegic homolog 3</fullName>
                    <alias typeAc="MI:0301" type="gene name">SMAD3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">MADH3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">SMAD family member 3</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">JV15-2</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P84022" version="SP_50" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3304356" version="SP_196"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1965323" refType="intact-secondary"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030335" secondary="positive regulation of cell migration" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030509" secondary="BMP signaling pathway" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060290" secondary="transdifferentiation" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042110" secondary="T cell activation" version="SP_196"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001138575.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" secondary="nucleus" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032924" secondary="activin receptor signaling pathway" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043425" secondary="bHLH transcription factor binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007492" secondary="endoderm development" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001657" secondary="ureteric bud development" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070412" secondary="R-SMAD binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000981" secondary="DNA-binding transcription factor activity, RNA polymerase II-specific" version="SP_196"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q92940" version="SP_50" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045668" secondary="negative regulation of osteoblast differentiation" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031625" secondary="ubiquitin protein ligase binding" version="SP_196"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1760241" refType="intact-secondary"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" secondary="DNA binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070306" secondary="lens fiber cell differentiation" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007183" secondary="SMAD protein complex assembly" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097191" secondary="extrinsic apoptotic signaling pathway" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030325" secondary="adrenal gland development" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070411" secondary="I-SMAD binding" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013019" version="SP_196"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1OZJ" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031962" secondary="mineralocorticoid receptor binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050821" secondary="protein stabilization" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048589" secondary="developmental growth" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051098" secondary="regulation of binding" version="SP_196"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q93002" version="SP_50" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1181150" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008134" secondary="transcription factor binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035259" secondary="glucocorticoid receptor binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032332" secondary="positive regulation of chondrocyte differentiation" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1901203" secondary="positive regulation of extracellular matrix assembly" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_196"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B7Z9Q2" version="SP_108" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031490" secondary="chromatin DNA binding" version="SP_196"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000332973" version="SP_196" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010694" secondary="positive regulation of alkaline phosphatase activity" version="SP_196"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1502540" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000987" secondary="cis-regulatory region sequence-specific DNA binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010628" secondary="positive regulation of gene expression" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071560" secondary="cellular response to transforming growth factor beta stimulus" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051496" secondary="positive regulation of stress fiber assembly" version="SP_196"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LAJ" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051091" secondary="positive regulation of DNA-binding transcription factor activity" version="SP_196"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5OD6" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006357" secondary="regulation of transcription by RNA polymerase II" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097296" secondary="activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050728" secondary="negative regulation of inflammatory response" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005637" secondary="nuclear inner membrane" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019901" secondary="protein kinase binding" version="SP_196"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P84022" version="SP_196"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3656532" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030501" secondary="positive regulation of bone mineralization" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" secondary="nucleoplasm" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038092" secondary="nodal signaling pathway" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001132" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006919" secondary="activation of cysteine-type endopeptidase activity involved in apoptotic process" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016202" secondary="regulation of striated muscle tissue development" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032731" secondary="positive regulation of interleukin-1 beta production" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009653" secondary="anatomical structure morphogenesis" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0017151" secondary="DEAD/H-box RNA helicase binding" version="SP_196"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K4B6" version="SP_76" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LB2" version="SP_196"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9617828" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045930" secondary="negative regulation of mitotic cell cycle" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001889" secondary="liver development" version="SP_196"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B7Z4Z5" version="SP_106" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045599" secondary="negative regulation of fat cell differentiation" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008013" secondary="beta-catenin binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" secondary="identical protein binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902895" secondary="positive regulation of pri-miRNA transcription by RNA polymerase II" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043235" secondary="receptor complex" version="SP_196"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-29720N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006955" secondary="immune response" version="SP_196"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000166949" version="SP_196" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001756" secondary="somitogenesis" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" secondary="RNA polymerase II cis-regulatory region sequence-specific DNA binding" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017855" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002520" secondary="immune system development" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007179" secondary="transforming growth factor beta receptor signaling pathway" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001947" secondary="heart looping" version="SP_196"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001138576.1"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2173788" version="SP_196"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013695" version="SP_196"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O09064" version="SP_50" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051726" secondary="regulation of cell cycle" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060039" secondary="pericardium development" version="SP_196"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_005893.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032909" secondary="regulation of transforming growth factor beta2 production" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_196"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8952158" version="SP_196"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9GKR4" version="SP_50" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000327367" version="SP_196" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005518" secondary="collagen binding" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008984" version="SP_196"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5XOC" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043130" secondary="ubiquitin binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048340" secondary="paraxial mesoderm morphogenesis" version="SP_196"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="F5H383" version="SP_115" refType="secondary-ac" refTypeAc="MI:0360"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031053" secondary="primary miRNA processing" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061767" secondary="negative regulation of lung blood pressure" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" secondary="negative regulation of apoptotic process" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" secondary="DNA-binding transcription activator activity, RNA polymerase II-specific" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" secondary="chromatin" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050678" secondary="regulation of epithelial cell proliferation" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045429" secondary="positive regulation of nitric oxide biosynthetic process" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009880" secondary="embryonic pattern specification" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002076" secondary="osteoblast development" version="SP_196"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" secondary="cytoplasm" version="SP_196"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0023019" secondary="signal transduction involved in regulation of gene expression" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001223" secondary="transcription coactivator binding" version="SP_196"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060395" secondary="SMAD protein signal transduction" version="SP_196"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030878" secondary="thyroid gland development" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005667" secondary="transcription regulator complex" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003619" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0090263" secondary="positive regulation of canonical Wnt signaling pathway" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010718" secondary="positive regulation of epithelial to mesenchymal transition" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050776" secondary="regulation of immune response" version="SP_196"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5ODG" version="SP_196"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2173795" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001701" secondary="in utero embryonic development" version="SP_196"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3315487" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071144" secondary="heteromeric SMAD protein complex" version="SP_196"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ZMN" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903243" secondary="negative regulation of cardiac muscle hypertrophy in response to stress" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071141" secondary="SMAD protein complex" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050927" secondary="positive regulation of positive chemotaxis" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042307" secondary="positive regulation of protein import into nucleus" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005160" secondary="transforming growth factor beta receptor binding" version="SP_196"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3311021" version="SP_196"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1MJS" version="SP_196"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001138574.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008270" secondary="zinc ion binding" version="SP_196"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1U7F" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001217" secondary="DNA-binding transcription repressor activity" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001707" secondary="mesoderm formation" version="SP_196"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043565" secondary="sequence-specific DNA binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0017015" secondary="regulation of transforming growth factor beta receptor signaling pathway" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030154" secondary="cell differentiation" version="SP_196"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042177" secondary="negative regulation of protein catabolic process" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061045" secondary="negative regulation of wound healing" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001666" secondary="response to hypoxia" version="SP_196"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000976" secondary="transcription cis-regulatory region binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048617" secondary="embryonic foregut morphogenesis" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061629" secondary="RNA polymerase II-specific DNA-binding transcription factor binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" secondary="positive regulation of transcription, DNA-templated" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042803" secondary="protein homodimerization activity" version="SP_196"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1MK2" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051481" secondary="negative regulation of cytosolic calcium ion concentration" version="SP_196"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9008059" version="SP_196"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-15729-2" id="1169895">
                <names>
                    <shortLabel>trim33-smad4-4</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8200350" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-15729-2" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6953176" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1169890</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1169896">
                        <names>
                            <shortLabel>smad4_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">SMAD4 </alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8200358" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6953185" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1169892</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1169897">
                        <names>
                            <shortLabel>tri33_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name"> TIF1G</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8200352" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6953182" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1169893</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>over-expressed</shortLabel>
                                    <fullName>over expressed level</fullName>
                                    <alias typeAc="MI:1041" type="synonym">over-expressed</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0506" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537736" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                    <attribute name="figure legend" nameAc="MI:0599">SF8D</attribute>
                </attributeList>
            </interaction>
            <interaction imexId="IM-15729-1" id="1169898">
                <names>
                    <shortLabel>smad3-smad4-5</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8200333" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6953212" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-15729-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>1169891</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1169899">
                        <names>
                            <shortLabel>smad4_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">SMAD4 </alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8200337" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6953224" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1169892</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>physiological level</shortLabel>
                                    <fullName>physiological level</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous level</alias>
                                    <alias typeAc="MI:0303" type="go synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous</alias>
                                    <alias typeAc="MI:1041" type="synonym">endogenous level</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1169900">
                        <names>
                            <shortLabel>tri33_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name"> TIF1G</alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8200335" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6953221" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1169893</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>western blot</shortLabel>
                                    <fullName>western blot</fullName>
                                    <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                                    <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>over-expressed</shortLabel>
                                    <fullName>over expressed level</fullName>
                                    <alias typeAc="MI:1041" type="synonym">over-expressed</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0506" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537736" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                    </participant>
                    <participant id="1169901">
                        <names>
                            <shortLabel>smad3_human</shortLabel>
                            <alias typeAc="MI:0345" type="author assigned name">SMAD3 </alias>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8200336" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6953218" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1169894</interactorRef>
                        <participantIdentificationMethodList>
                            <participantIdentificationMethod>
                                <names>
                                    <shortLabel>anti tag western</shortLabel>
                                    <fullName>anti tag western blot</fullName>
                                    <alias typeAc="MI:1041" type="synonym">anti tag western</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0705" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-967832" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </participantIdentificationMethod>
                        </participantIdentificationMethodList>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <experimentalPreparationList>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>over-expressed</shortLabel>
                                    <fullName>over expressed level</fullName>
                                    <alias typeAc="MI:1041" type="synonym">over-expressed</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0506" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537736" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalPreparation>
                            <experimentalPreparation>
                                <names>
                                    <shortLabel>living cell</shortLabel>
                                    <fullName>living cell</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalPreparation>
                        </experimentalPreparationList>
                        <featureList>
                            <feature id="1169902">
                                <names>
                                    <shortLabel>flag tag</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8200344" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6953227" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>flag tag</shortLabel>
                                        <fullName>flag tag</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">FLAG-tagged</alias>
                                        <alias typeAc="MI:0303" type="go synonym">FLAG</alias>
                                        <alias typeAc="MI:0303" type="go synonym">DYKDDDDKV epitope tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">DYKDDDDKV epitope tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">FLAG</alias>
                                        <alias typeAc="MI:1041" type="synonym">FLAG-tagged</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0518" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456503" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                    <attribute name="figure legend" nameAc="MI:0599">SF8A</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
