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    <entry>
        <source releaseDate="2011-07-27+01:00">
            <names>
                <shortLabel>IntAct</shortLabel>
                <fullName>European Bioinformatics Institute</fullName>
                <alias typeAc="MI:1041" type="synonym">IntAct</alias>
                <alias typeAc="MI:1041" type="synonym">intact</alias>
            </names>
            <bibref>
                <xref>
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                </xref>
            </bibref>
            <xref>
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            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
                <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
                <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
                <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
                <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
                <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
                <attribute name="url">http://www.ebi.ac.uk/</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="1161012">
                <names>
                    <shortLabel>oleksiuk-2011-1</shortLabel>
                    <fullName>Thermal robustness of signaling in bacterial chemotaxis.</fullName>
                </names>
                <bibref>
                    <xref>
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                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="-1">
                        <names>
                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>fret</shortLabel>
                        <fullName>fluorescent resonance energy transfer</fullName>
                        <alias typeAc="MI:0303" type="go synonym">FRET</alias>
                        <alias typeAc="MI:0303" type="go synonym">RET</alias>
                        <alias typeAc="MI:0303" type="go synonym">FRET analysis</alias>
                        <alias typeAc="MI:1041" type="synonym">FRET</alias>
                        <alias typeAc="MI:1041" type="synonym">RET</alias>
                        <alias typeAc="MI:1041" type="synonym">FRET analysis</alias>
                        <alias typeAc="MI:1041" type="synonym">fret</alias>
                    </names>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>tag fluorescence</shortLabel>
                        <fullName>tag visualisation by fluorescence</fullName>
                        <alias typeAc="MI:1041" type="synonym">tag fluorescence</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0867" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1372411" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Oleksiuk O., Jakovljevic V., Vladimirov N., Carvalho R., Paster E., Ryu WS., Meir Y., Wingreen NS., Kollmann M., Sourjik V.</attribute>
                    <attribute name="comment" nameAc="MI:0612">This interaction was used as a readout in a series of experiments examining how bacterial signalling responds to changes in temperature.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">v.sourjik@zmbh.uni-heidelberg.de</attribute>
                    <attribute name="journal" nameAc="MI:0885">Cell (0092-8674)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2011</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="1161013">
                <names>
                    <shortLabel>chey_ecoli</shortLabel>
                    <fullName>Chemotaxis protein CheY</fullName>
                    <alias typeAc="MI:0301" type="gene name">cheY</alias>
                    <alias typeAc="MI:0305" type="locus name">b1882</alias>
                    <alias typeAc="MI:0305" type="locus name">JW1871</alias>
                </names>
                <xref>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1AB5" version="SP_140"/>
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                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-6052N"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1AB6" version="SP_140"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006935" secondary="chemotaxis" version="SP_140"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1MIH" version="SP_140"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3RVP" version="SP_140"/>
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                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2ID7" version="SP_140"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097588" secondary="archaeal or bacterial-type flagellum-dependent cell motility" version="SP_140"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="83333">
                    <names>
                        <shortLabel>ecoli</shortLabel>
                        <fullName>Escherichia coli (strain K12)</fullName>
                    </names>
                </organism>
                <sequence>MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPFTAATLEEKLNKIFEKLGM</sequence>
            </interactor>
            <interactor id="1161014">
                <names>
                    <shortLabel>chez_ecoli</shortLabel>
                    <fullName>Protein phosphatase CheZ</fullName>
                    <alias typeAc="MI:0301" type="gene name">cheZ</alias>
                    <alias typeAc="MI:0305" type="locus name">b1881</alias>
                    <alias typeAc="MI:0305" type="locus name">JW1870</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Chemotaxis protein CheZ</alias>
                </names>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_113"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="WP_000983609.1"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006470" secondary="protein dephosphorylation" version="SP_113"/>
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                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="83333">
                    <names>
                        <shortLabel>ecoli</shortLabel>
                        <fullName>Escherichia coli (strain K12)</fullName>
                    </names>
                </organism>
                <sequence>MMQPSIKPADEHSAGDIIARIGSLTRMLRDSLRELGLDQAIAEAAEAIPDARDRLYYVVQMTAQAAERALNSVEASQPHQDQMEKSAKALTQRWDDWFADPIDLADARELVTDTRQFLADVPAHTSFTNAQLLEIMMAQDFQDLTGQVIKRMMDVIQEIERQLLMVLLENIPEQESRPKRENQSLLNGPQVDTSKAGVVASQDQVDDLLDSLGF</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-15805-1" id="1161015">
                <names>
                    <shortLabel>chey-chez-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-4279727" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-15805-1" refType="imex-primary" refTypeAc="MI:0662"/>
                    <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0469" refType="imex source"/>
                </xref>
                <experimentList>
                    <experimentRef>1161012</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1161016">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4279729" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1161013</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>fluorescence accept</shortLabel>
                                    <fullName>fluorescence acceptor</fullName>
                                    <alias typeAc="MI:1041" type="synonym">fluorescence accept</alias>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0584" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-704935" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1161017">
                                <names>
                                    <shortLabel>region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-4279730" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>yfp tag</shortLabel>
                                        <fullName>yellow fluorescent protein tag</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">YFP</alias>
                                        <alias typeAc="MI:0303" type="go synonym">yellow fluorescent protein</alias>
                                        <alias typeAc="MI:1041" type="synonym">yellow fluorescent protein</alias>
                                        <alias typeAc="MI:1041" type="synonym">YFP</alias>
                                        <alias typeAc="MI:1041" type="synonym">yfp tag</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0368" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608966" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="10929120" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                    <participant id="1161018">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4279728" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1161014</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>fluorescence donor</shortLabel>
                                    <fullName>fluorescence donor</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0583" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-704939" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="1161019">
                                <names>
                                    <shortLabel>region</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-4279732" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>cfp tag</shortLabel>
                                        <fullName>cyan fluorescent protein tag</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">CFP</alias>
                                        <alias typeAc="MI:0303" type="go synonym">cyan fluorescent protein</alias>
                                        <alias typeAc="MI:1041" type="synonym">cyan fluorescent protein</alias>
                                        <alias typeAc="MI:1041" type="synonym">CFP</alias>
                                        <alias typeAc="MI:1041" type="synonym">cfp tag</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0733" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-967984" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>undetermined</shortLabel>
                                                <fullName>undetermined sequence position</fullName>
                                                <alias typeAc="MI:1041" type="synonym">undetermined</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>direct interaction</shortLabel>
                        <fullName>direct interaction</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">S1A-C</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
