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                <names>
                    <shortLabel>luo-2011a-1</shortLabel>
                    <fullName>Proteinase-activated receptors, nucleotide P2Y receptors, and μ-opioid receptor-1B are under the control of the type I transmembrane proteins p23 and p24A in post-Golgi trafficking.</fullName>
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                        <names>
                            <shortLabel>human</shortLabel>
                            <fullName>Homo sapiens</fullName>
                            <alias typeAc="MI:1041" type="synonym">Human</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti tag coip</shortLabel>
                        <fullName>anti tag coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti tag coip</alias>
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                    <names>
                        <shortLabel>anti tag western</shortLabel>
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                    <attribute name="author-list" nameAc="MI:0636">Luo W., Wang Y., Reiser G.</attribute>
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                    <attribute name="journal" nameAc="MI:0885">J. Neurochem. (0022-3042)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2011</attribute>
                    <attribute name="curation depth" nameAc="MI:0955">mimix curation</attribute>
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            <experimentDescription id="1179474">
                <names>
                    <shortLabel>luo-2011a-13</shortLabel>
                    <fullName>Proteinase-activated receptors, nucleotide P2Y receptors, and μ-opioid receptor-1B are under the control of the type I transmembrane proteins p23 and p24A in post-Golgi trafficking.</fullName>
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                        <names>
                            <shortLabel>human</shortLabel>
                            <fullName>Homo sapiens</fullName>
                            <alias typeAc="MI:1041" type="synonym">Human</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>confocal microscopy</shortLabel>
                        <fullName>confocal microscopy</fullName>
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                <participantIdentificationMethod>
                    <names>
                        <shortLabel>anti tag immunost</shortLabel>
                        <fullName>anti tag immunostaining</fullName>
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                    <attribute name="author-list" nameAc="MI:0636">Luo W., Wang Y., Reiser G.</attribute>
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                    <attribute name="journal" nameAc="MI:0885">J. Neurochem. (0022-3042)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2011</attribute>
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                <names>
                    <shortLabel>luo-2011a-7</shortLabel>
                    <fullName>Proteinase-activated receptors, nucleotide P2Y receptors, and μ-opioid receptor-1B are under the control of the type I transmembrane proteins p23 and p24A in post-Golgi trafficking.</fullName>
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                        <names>
                            <shortLabel>in vitro</shortLabel>
                            <fullName>In vitro</fullName>
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                    <names>
                        <shortLabel>pull down</shortLabel>
                        <fullName>pull down</fullName>
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                    <attribute name="curation depth" nameAc="MI:0955">mimix curation</attribute>
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            <interactor id="1179476">
                <names>
                    <shortLabel>tmed2_human</shortLabel>
                    <fullName>Transmembrane emp24 domain-containing protein 2</fullName>
                    <alias typeAc="MI:0301" type="gene name">TMED2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">RNP24</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Membrane protein p24A</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">p24 family protein beta-1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">p24</alias>
                </names>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033116" secondary="endoplasmic reticulum-Golgi intermediate compartment membrane" version="SP_175"/>
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                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5694530" version="SP_175"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001843" secondary="neural tube closure" version="SP_175"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0036342" secondary="post-anal tail morphogenesis" version="SP_175"/>
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                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
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                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
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                <sequence>MVTLAELLVLLAALLATVSGYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV</sequence>
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                    <shortLabel>par1_human</shortLabel>
                    <fullName>Proteinase-activated receptor 1</fullName>
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                    <alias typeAc="MI:0302" type="gene name synonym">TR</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Coagulation factor II receptor</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Thrombin receptor</alias>
                    <alias typeAc="MI:0301" type="gene name">F2R</alias>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043410" secondary="positive regulation of MAPK cascade" version="SP_220"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007205" secondary="protein kinase C-activating G protein-coupled receptor signaling pathway" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051209" secondary="release of sequestered calcium ion into cytosol" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007186" secondary="G protein-coupled receptor signaling pathway" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008285" secondary="negative regulation of cell population proliferation" version="SP_220"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1NRR" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035025" secondary="positive regulation of Rho protein signal transduction" version="SP_220"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3BEF" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030194" secondary="positive regulation of blood coagulation" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070374" secondary="positive regulation of ERK1 and ERK2 cascade" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_220"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1NRQ" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031094" secondary="platelet dense tubular network" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015057" secondary="thrombin-activated receptor activity" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045211" secondary="postsynaptic membrane" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005901" secondary="caveola" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004930" secondary="G protein-coupled receptor activity" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" secondary="cell surface" version="SP_220"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-456926" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051928" secondary="positive regulation of calcium ion transport" version="SP_220"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3HKJ" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" secondary="Golgi apparatus" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002248" secondary="connective tissue replacement involved in inflammatory response wound healing" version="SP_220"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1NRP" version="SP_220"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2803960" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003105" secondary="negative regulation of glomerular filtration" version="SP_220"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53XV0" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1NRO" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031594" secondary="neuromuscular junction" version="SP_220"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-140875" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005102" secondary="signaling receptor binding" version="SP_220"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001983.2"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" secondary="positive regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_220"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9BUN4" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045987" secondary="positive regulation of smooth muscle contraction" version="SP_220"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017452" version="SP_220"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3HKI" version="SP_220"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000319211" version="SP_220" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900134" secondary="negative regulation of renin secretion into blood stream" version="SP_220"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3VW7" version="SP_220"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1NRN" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008284" secondary="positive regulation of cell population proliferation" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060155" secondary="platelet dense granule organization" version="SP_220"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032755" secondary="positive regulation of interleukin-6 production" version="SP_220"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MGPRRLLLVAACFSLCGPLLSARTRARRPESKATNATLDPRSFLLRNPNDKYEPFWEDEEKNESGLTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSLPLNIMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRFVTAAFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALAIAGVVPLLLKEQTIQVPGLNITTCHDVLNETLLEGYYAYYFSAFSAVFFFVPLIISTVCYVSIIRCLSSSAVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSHTSTTEAAYFAYLLCVCVSSISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMASKMDTCSSNLNNSIYKKLLT</sequence>
            </interactor>
            <interactor id="1179478">
                <names>
                    <shortLabel>p2ry4_human</shortLabel>
                    <fullName>P2Y purinoceptor 4</fullName>
                    <alias typeAc="MI:0301" type="gene name">P2RY4</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">NRU</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">P2P</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Uridine nucleotide receptor</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P51582" version="SP_94" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0099509" secondary="regulation of presynaptic cytosolic calcium ion concentration" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045030" secondary="G protein-coupled UTP receptor activity" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071380" secondary="cellular response to prostaglandin E stimulus" version="SP_174"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000018" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016324" secondary="apical plasma membrane" version="SP_174"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000363643" version="SP_174" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016323" secondary="basolateral plasma membrane" version="SP_174"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017452" version="SP_174"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-4392513" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000374519" version="SP_174" refType="transcript"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q502W2" version="SP_94" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030321" secondary="transepithelial chloride transport" version="SP_174"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q4VBB7" version="SP_94" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007204" secondary="positive regulation of cytosolic calcium ion concentration" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007200" secondary="phospholipase C-activating G protein-coupled receptor signaling pathway" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0098978" secondary="glutamatergic synapse" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" secondary="ATP binding" version="SP_174"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-417957" version="SP_174"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q4VBB8" version="SP_94" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000300" secondary="regulation of synaptic vesicle exocytosis" version="SP_174"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000186912" version="SP_174" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045028" secondary="G protein-coupled purinergic nucleotide receptor activity" version="SP_174"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2B6Q" version="SP_174"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_002556.1"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000276" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0099059" secondary="integral component of presynaptic active zone membrane" version="SP_174"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5JT22" version="SP_94" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-418594" version="SP_174"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071318" secondary="cellular response to ATP" version="SP_174"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL</sequence>
            </interactor>
            <interactor id="1179479">
                <names>
                    <shortLabel>p2y11_human</shortLabel>
                    <fullName>P2Y purinoceptor 11</fullName>
                    <alias typeAc="MI:0301" type="gene name">P2RY11</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q96G91" version="SP_89" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O43190" version="SP_89" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_002557.2"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-418555" version="SP_173"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017452" version="SP_173"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0023041" secondary="neuronal signal transduction" version="SP_173"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-4392539" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030594" secondary="neurotransmitter receptor activity" version="SP_173"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038023" secondary="signaling receptor activity" version="SP_173"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9H170" version="SP_89" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000244165" version="SP_173" refType="gene"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2B6S" version="SP_173"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006952" secondary="defense response" version="SP_173"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000321826" version="SP_173" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007186" secondary="G protein-coupled receptor signaling pathway" version="SP_173"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007200" secondary="phospholipase C-activating G protein-coupled receptor signaling pathway" version="SP_173"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9660821" version="SP_173"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000323872" version="SP_173" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007190" secondary="activation of adenylate cyclase activity" version="SP_173"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_173"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027677" version="SP_173"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-417957" version="SP_173"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_173"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9BYU4" version="SP_89" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B2R8X9" version="SP_89" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000276" version="SP_173"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045031" secondary="G protein-coupled ATP receptor activity" version="SP_173"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-416476" version="SP_173"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0071318" secondary="cellular response to ATP" version="SP_173"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019722" secondary="calcium-mediated signaling" version="SP_173"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNCSVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTVAEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATAAPKPSEPQSRELSQ</sequence>
            </interactor>
            <interactor id="1179480">
                <names>
                    <shortLabel>p33535-4</shortLabel>
                    <fullName>Mu-type opioid receptor</fullName>
                    <alias typeAc="MI:0304" type="isoform synonym">MOR1B</alias>
                    <alias typeAc="MI:0301" type="gene name">Oprm1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Ror-b</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Opioid receptor B</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P33535-4" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-4392569" refType="isoform-parent" refTypeAc="MI:0243"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-5281984" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="10116">
                    <names>
                        <shortLabel>rat</shortLabel>
                        <fullName>Rattus norvegicus (Rat)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Rat</alias>
                    </names>
                </organism>
                <sequence>MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRVRQNTREHPSTANTVDRTNHQKIVLF</sequence>
            </interactor>
            <interactor id="1179481">
                <names>
                    <shortLabel>tmeda_human</shortLabel>
                    <fullName>Transmembrane emp24 domain-containing protein 10</fullName>
                    <alias typeAc="MI:0302" type="gene name synonym">21 kDa transmembrane-trafficking protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Transmembrane protein Tmp21</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Tmp-21-I</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">p24delta</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">S31III125</alias>
                    <alias typeAc="MI:0301" type="gene name">TMED10</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">TMP21</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">p23</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">p24 family protein delta-1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">S31I125</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P49755" version="SP_74" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q15602" version="SP_74" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030133" secondary="transport vesicle" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048199" secondary="vesicle targeting, to, from or within Golgi" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0019905" secondary="syntaxin binding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030140" secondary="trans-Golgi network transport vesicle" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042589" secondary="zymogen granule membrane" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050714" secondary="positive regulation of protein secretion" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009038" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043279" secondary="response to alkaloid" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902960" secondary="negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035964" secondary="COPI-coated vesicle budding" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070765" secondary="gamma-secretase complex" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030134" secondary="COPII-coated ER to Golgi transport vesicle" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006890" secondary="retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum" version="SP_196"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000170348" version="SP_196" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045055" secondary="regulated exocytosis" version="SP_196"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000303145" version="SP_196" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-998422" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042470" secondary="melanosome" version="SP_196"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5694530" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106273" secondary="cytosol to ERGIC protein transport" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030137" secondary="COPI-coated vesicle" version="SP_196"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_006818.3"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006886" secondary="intracellular protein transport" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007030" secondary="Golgi organization" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032732" secondary="positive regulation of interleukin-1 production" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030667" secondary="secretory granule membrane" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0033116" secondary="endoplasmic reticulum-Golgi intermediate compartment membrane" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" secondary="Golgi apparatus" version="SP_196"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015720" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0000139" secondary="Golgi membrane" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005789" secondary="endoplasmic reticulum membrane" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005793" secondary="endoplasmic reticulum-Golgi intermediate compartment" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" secondary="integral component of membrane" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005783" secondary="endoplasmic reticulum" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044877" secondary="protein-containing complex binding" version="SP_196"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q86TC2" version="SP_74" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048205" secondary="COPI coating of Golgi vesicle" version="SP_196"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6807878" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005801" secondary="cis-Golgi network" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035459" secondary="vesicle cargo loading" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001822" secondary="kidney development" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0106272" secondary="protein localization to ERGIC" version="SP_196"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q86TS5" version="SP_74" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0048208" secondary="COPII vesicle coating" version="SP_196"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P49755" version="SP_196"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q16536" version="SP_74" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006888" secondary="endoplasmic reticulum to Golgi vesicle-mediated transport" version="SP_196"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1058680" refType="intact-secondary"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0008320" secondary="protein transmembrane transporter activity" version="SP_196"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0012507" secondary="ER to Golgi transport vesicle membrane" version="SP_196"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B2R605" version="SP_97" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000303575" version="SP_196" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1902003" secondary="regulation of amyloid-beta formation" version="SP_196"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-204005" version="SP_196"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6811434" version="SP_196"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MSGLSGPPARRGPFPLALLLLFLLGPRLVLAISFHLPINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE</sequence>
            </interactor>
            <interactor id="1179482">
                <names>
                    <shortLabel>par2_human</shortLabel>
                    <fullName>Proteinase-activated receptor 2</fullName>
                    <alias typeAc="MI:0301" type="gene name">F2RL1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">GPR11</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">PAR2</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Coagulation factor II receptor-like 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">G-protein coupled receptor 11</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Thrombin receptor-like 1</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P55085" version="SP_109" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030335" secondary="positive regulation of cell migration" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010804" secondary="negative regulation of tumor necrosis factor-mediated signaling pathway" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1900135" secondary="positive regulation of renin secretion into blood stream" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070963" secondary="positive regulation of neutrophil mediated killing of gram-negative bacterium" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045217" secondary="cell-cell junction maintenance" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002286" secondary="T cell activation involved in immune response" version="SP_195"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q13346" version="SP_109" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:2000341" secondary="regulation of chemokine (C-X-C motif) ligand 2 production" version="SP_195"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5NJ6" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032682" secondary="negative regulation of chemokine production" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005102" secondary="signaling receptor binding" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051482" secondary="positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045087" secondary="innate immune response" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031681" secondary="G-protein beta-subunit binding" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032733" secondary="positive regulation of interleukin-10 production" version="SP_195"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5NDZ" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042311" secondary="vasodilation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" secondary="plasma membrane" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0060100" secondary="positive regulation of phagocytosis, engulfment" version="SP_195"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-375276" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030193" secondary="regulation of blood coagulation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0001965" secondary="G-protein alpha-subunit binding" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032930" secondary="positive regulation of superoxide anion generation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031143" secondary="pseudopodium" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051607" secondary="defense response to virus" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0014068" secondary="positive regulation of phosphatidylinositol 3-kinase signaling" version="SP_195"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000276" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032757" secondary="positive regulation of interleukin-8 production" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043311" secondary="positive regulation of eosinophil degranulation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070661" secondary="leukocyte proliferation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0015057" secondary="thrombin-activated receptor activity" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046328" secondary="regulation of JNK cascade" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0061028" secondary="establishment of endothelial barrier" version="SP_195"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000296677" version="SP_195" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002281" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0004930" secondary="G protein-coupled receptor activity" version="SP_195"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P55085" version="SP_195"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-42044N"/>
                    <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5NDD" version="SP_195"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003912" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0097029" secondary="mature conventional dendritic cell differentiation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007596" secondary="blood coagulation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032731" secondary="positive regulation of interleukin-1 beta production" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043122" secondary="regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_195"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-4303189" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017452" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050927" secondary="positive regulation of positive chemotaxis" version="SP_195"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000164251" version="SP_195" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032729" secondary="positive regulation of interferon-gamma production" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034145" secondary="positive regulation of toll-like receptor 4 signaling pathway" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046330" secondary="positive regulation of JNK cascade" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0038023" secondary="signaling receptor activity" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043123" secondary="positive regulation of I-kappaB kinase/NF-kappaB signaling" version="SP_195"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53XJ8" version="SP_120" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0003104" secondary="positive regulation of glomerular filtration" version="SP_195"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q13317" version="SP_109" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032755" secondary="positive regulation of interleukin-6 production" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034137" secondary="positive regulation of toll-like receptor 2 signaling pathway" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034141" secondary="positive regulation of toll-like receptor 3 signaling pathway" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002690" secondary="positive regulation of leukocyte chemotaxis" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005769" secondary="early endosome" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007204" secondary="positive regulation of cytosolic calcium ion concentration" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0002720" secondary="positive regulation of cytokine production involved in immune response" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007186" secondary="G protein-coupled receptor signaling pathway" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0034140" secondary="negative regulation of toll-like receptor 3 signaling pathway" version="SP_195"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_005233.3"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030836" secondary="positive regulation of actin filament depolymerization" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006954" secondary="inflammatory response" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0035025" secondary="positive regulation of Rho protein signal transduction" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0042119" secondary="neutrophil activation" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0046329" secondary="negative regulation of JNK cascade" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005887" secondary="integral component of plasma membrane" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0070374" secondary="positive regulation of ERK1 and ERK2 cascade" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050900" secondary="leukocyte migration" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" secondary="positive regulation of transcription by RNA polymerase II" version="SP_195"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-416476" version="SP_195"/>
                    <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000296677" version="SP_195" refType="transcript"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0032722" secondary="positive regulation of chemokine production" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" secondary="Golgi apparatus" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031274" secondary="positive regulation of pseudopodium assembly" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0050921" secondary="positive regulation of chemotaxis" version="SP_195"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0043547" secondary="positive regulation of GTPase activity" version="SP_195"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="9606">
                    <names>
                        <shortLabel>human</shortLabel>
                        <fullName>Homo sapiens</fullName>
                        <alias typeAc="MI:1041" type="synonym">Human</alias>
                    </names>
                </organism>
                <sequence>MRSPSAAWLLGAAILLAASLSCSGTIQGTNRSSKGRSLIGKVDGTSHVTGKGVTVETVFSVDEFSASVLTGKLTTVFLPIVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGNNWIYGEALCNVLIGFFYGNMYCSILFMTCLSVQRYWVIVNPMGHSRKKANIAIGISLAIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYFLSLAIGVFLFPAFLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIKSQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRSVRTVKQMQVSLTSKKHSRKSSSYSSSSTTVKTSY</sequence>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="1179483">
                <names>
                    <shortLabel>f2r-tmed2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-4392507" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1179473</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1179484">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4392510" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179476</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1179485">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4392509" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179477</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">1a</attribute>
                </attributeList>
            </interaction>
            <interaction id="1179486">
                <names>
                    <shortLabel>p2ry4-tmed2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-4392511" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1179473</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1179487">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4392538" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179476</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1179488">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4392537" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179478</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">1b and 4</attribute>
                </attributeList>
            </interaction>
            <interaction id="1179489">
                <names>
                    <shortLabel>p2ry11-tmed2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-4392563" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1179473</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1179490">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4392566" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179476</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1179491">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4392565" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179479</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">1c and 3</attribute>
                </attributeList>
            </interaction>
            <interaction id="1179492">
                <names>
                    <shortLabel>oprm1-oprm1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-4392567" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1179473</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1179493">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-5281992" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179480</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1179494">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4392610" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179476</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">1d</attribute>
                </attributeList>
            </interaction>
            <interaction id="1179495">
                <names>
                    <shortLabel>f2rl1-tmed10</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-4394487" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1179473</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1179496">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4394490" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179481</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1179497">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4394489" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179482</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">5a</attribute>
                </attributeList>
            </interaction>
            <interaction id="1179498">
                <names>
                    <shortLabel>f2rl1-tmed10-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-4394500" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" refType="component" refTypeAc="MI:0354"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" secondary="Golgi apparatus" refType="component" refTypeAc="MI:0354"/>
                </xref>
                <experimentList>
                    <experimentRef>1179474</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1179499">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4394503" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179481</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1179500">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4394502" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179482</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">5b</attribute>
                </attributeList>
            </interaction>
            <interaction id="1179501">
                <names>
                    <shortLabel>oprm1-oprm1-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-4394512" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005794" secondary="Golgi apparatus" refType="component" refTypeAc="MI:0354"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" refType="component" refTypeAc="MI:0354"/>
                </xref>
                <experimentList>
                    <experimentRef>1179474</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1179502">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-5282111" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179480</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1179503">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4394514" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179476</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>neutral component</shortLabel>
                                    <fullName>neutral component</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>colocalization</shortLabel>
                        <fullName>colocalization</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0403" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608832" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">6a</attribute>
                </attributeList>
            </interaction>
            <interaction id="1179504">
                <names>
                    <shortLabel>f2rl1-tmed2-5</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-4394482" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1179475</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1179505">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4394485" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179482</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1179506">
                        <names>
                            <shortLabel>n/a</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-4394484" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1179476</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">2a</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
