InnateDB InnateDB collison-2010-1 IL-35-mediated induction of a potent regulatory T cell population. mouse-t-cell Mouse T cell t-cell Peripheral blood T-lymphocytes anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Collison LW., Chaturvedi V., Henderson AL., Giacomin PR., Guy C., Bankoti J., Finkelstein D., Forbes K., Workman CJ., Brown SA., Rehg JE., Jones ML., Ni HT., Artis D., Turk MJ., Vignali DA. Fig. 6G. used CD4+ T cells from the spleen and tumor in Foxp3(gfp) mice. vignali.lab@stjude.org Nat. Immunol. (1529-2908) 2010 Only protein-protein interactions imex curation Curated by: InnateDB - a knowledge resource for innate immunity il27b_mouse Interleukin-27 subunit beta Ebi3 Epstein-Barr virus-induced gene 3 protein homolog Il27b protein protein mouse Mus musculus Mouse MSKLLFLSLALWASRSPGYTETALVALSQPRVQCHASRYPVAVDCSWTPLQAPNSTRSTSFIATYRLGVATQQQSQPCLQRSPQASRCTIPDVHLFSTVPYMLNVTAVHPGGASSSLLAFVAERIIKPDPPEGVRLRTAGQRLQVLWHPPASWPFPDIFSLKYRLRYRRRGASHFRQVGPIEATTFTLRNSKPHAKYCIQVSAQDLTDYGKPSDWSLPGQVESAPHKP il12a_mouse Interleukin-12 subunit alpha Il12a Cytotoxic lymphocyte maturation factor 35 kDa subunit IL-12 subunit p35 protein protein mouse Mus musculus Mouse MCQSRYLLFLATLALLNHLSLARVIPVSGPARCLSQSRNLLKTTDDMVKTAREKLKHYSCTAEDIDHEDITRDQTSTLKTCLPLELHKNESCLATRETSSTTRGSCLPPQKTSLMMTLCLGSIYEDLKMYQTEFQAINAALQNHNHQQIILDKGMLVAIDELMQSLNHNGETLRQKPPVGEADPYRVKMKLCILLHAFSTRVVTINRVMGYLSSA il12a-il27b 1132207 n/a 1132208 unspecified role unspecified role prey prey n/a 1132209 unspecified role unspecified role bait bait physical association physical association false false false Fig. 2B, 5C, 6G IL-35 IL-35 interaction not detected in Foxp3-/- splenic T cells, however, the interaction was present in Foxp3-/- tumour cells