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        <source releaseDate="2013-09-02+01:00">
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                <shortLabel>MINT</shortLabel>
                <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
                <alias typeAc="MI:1041" type="synonym">MINT</alias>
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                <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
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                <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
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                <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
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                <attribute name="url">http://mint.bio.uniroma2.it/mint</attribute>
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            <experimentDescription id="1190023">
                <names>
                    <shortLabel>kolupaeva-2008-1</shortLabel>
                    <fullName>PP2A-mediated dephosphorylation of p107 plays a critical role in chondrocyte cell cycle arrest by FGF.</fullName>
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                            <shortLabel>rat</shortLabel>
                            <fullName>Rattus norvegicus (Rat)</fullName>
                            <alias typeAc="MI:1041" type="synonym">Rat</alias>
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                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti bait coip</shortLabel>
                        <fullName>anti bait coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti bait coip</alias>
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                    <names>
                        <shortLabel>western blot</shortLabel>
                        <fullName>western blot</fullName>
                        <alias typeAc="MI:0303" type="go synonym">Immuno blot</alias>
                        <alias typeAc="MI:1041" type="synonym">Immuno blot</alias>
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                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Kolupaeva V., Laplantine E., Basilico C.</attribute>
                    <attribute name="journal" nameAc="MI:0885">PLoS ONE</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2008</attribute>
                    <attribute name="partial coverage" nameAc="MI:0958">partial coverage</attribute>
                    <attribute name="rapid curation" nameAc="MI:0961">rapid curation</attribute>
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            </experimentDescription>
        </experimentList>
        <interactorList>
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                <names>
                    <shortLabel>pp2aa_rat</shortLabel>
                    <fullName>Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform</fullName>
                    <alias typeAc="MI:0301" type="gene name">Ppp2ca</alias>
                </names>
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                        <shortLabel>rat</shortLabel>
                        <fullName>Rattus norvegicus (Rat)</fullName>
                        <alias typeAc="MI:1041" type="synonym">Rat</alias>
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                <sequence>MDEKLFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL</sequence>
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                    <attribute name="function" nameAc="MI:0613">PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase</attribute>
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                    <shortLabel>rbl1_rat</shortLabel>
                    <fullName>Retinoblastoma-like protein 1</fullName>
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                    <alias typeAc="MI:0302" type="gene name synonym">107 kDa retinoblastoma-associated protein</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">pRb1</alias>
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                        <shortLabel>rat</shortLabel>
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                        <alias typeAc="MI:1041" type="synonym">Rat</alias>
                    </names>
                </organism>
                <sequence>MFEDEPHAEGAAAVAAAREALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVIHWLACSLYVACRKSIIPTVGKGVMEGNCVSLTRILRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKFEPIFLDIFQNPYEELPKLPRSRKQRRIPCSVKDLFNFCWTLFVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRRDLLNPSFKGLPSDFHAVNFKAAEEPPCIIAVLCDLHDGLLVEAKGIKEHYFKPYISKLFDKKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFAADTQFGKLTSQASVDCNLQQHFEKKRSFAPSTPLTGRRYLQEKEAVTTPVASATQSVSRLQSIVAGLKSAPSEQLLTIFESCMRNPMGNIVKIVKGIGETFCQHYTQSTDKQPGSHIDFAVNRLKLAEILYYKILETIMVQETRRLHGMDMSVLLEQDIFHRSLLACCLEIVLFAYSSPRTFPWIIDVLGLQPFYFYKVIEVVIRSEEGLSRDMVKHLNSIEEQILESLAWTNNSALWEALRASANKVPSCEEVIFPNNFEIGNGGSVQGHLPMMPMSPIIHPRVKEVRTDSGSLRKDMQPLSPISVHERYSSPAAGSAKRRLFGDDPPKETLMEKIMAEGTQLKIAPSSVTAESLSISPGQALLTMATTTVTGTTGRKVTVPLHGIANDAGEITLVPISMNTTQDSTAESLVSLTAQSLIGASPKQTHLTKTQDAPLTGISKPKRTGSLALFYRKVYHLASVRLRDLCLKLDVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKVTKEERTFQEIMKSYRNQPQANSHVYRSVLLKSIPGEVVAYNGDYEMTDGDIEDATKTPNCSSEPVKEERGDLIKFYNAIYVGRVKSFALKYDLSNQDHIMDAPPLSPFPHIKQQPGSPRRISQQHSIYVSPHKNASGLTPRSALLYKFNGSPSKKAKKRVIAISGDAESPAKRLCQENDDVLLKRLQDVVSERANH</sequence>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                </attributeList>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction id="1190026">
                <names>
                    <shortLabel>ppp2ca-rbl1-2</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8214129" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8450243" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1190023</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1190027">
                        <names>
                            <shortLabel>pp2aa_rat</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8214131" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8450250" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1190024</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1190028">
                        <names>
                            <shortLabel>d3zs28_rat</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8214132" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8450248" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1190025</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">F5A</attribute>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                    <attribute name="comment" nameAc="MI:0612">PP2A subunits also present</attribute>
                </attributeList>
            </interaction>
            <interaction id="1190029">
                <names>
                    <shortLabel>rbl1-ppp2ca-1</shortLabel>
                </names>
                <xref>
                    <primaryRef db="mint" dbAc="MI:0471" id="MINT-8214248" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8450269" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <experimentList>
                    <experimentRef>1190023</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="1190030">
                        <names>
                            <shortLabel>pp2aa_rat</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8214250" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8450276" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1190024</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                    <participant id="1190031">
                        <names>
                            <shortLabel>d3zs28_rat</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="mint" dbAc="MI:0471" id="MINT-8214251" refType="identity" refTypeAc="MI:0356"/>
                            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8450274" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>1190025</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>association</shortLabel>
                        <fullName>association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="comment" nameAc="MI:0612">homomint</attribute>
                    <attribute name="comment" nameAc="MI:0612">mint</attribute>
                    <attribute name="figure legend" nameAc="MI:0599">F5B</attribute>
                    <attribute name="comment" nameAc="MI:0612">PP2A subunits also present</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
