IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ asher-2010-1 Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding. mouse-liver Mus musculus liver liver anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Asher G., Reinke H., Altmeyer M., Gutierrez-Arcelus M., Hottiger MO., Schibler U. Mice were sacrificed at 4 hr intervals around the clock, and liver nuclear extracts were prepared gad.asher@unige.ch Zeitgeber time (ZT) Cell (0092-8674) 2010 Only protein-protein interactions imex curation asher-2010-6 Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding. mouse-liver Mus musculus liver liver anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Asher G., Reinke H., Altmeyer M., Gutierrez-Arcelus M., Hottiger MO., Schibler U. Mice were sacrificed at 4 hr intervals around the clock, and liver nuclear extracts were prepared gad.asher@unige.ch Zeitgeber time (ZT) Cell (0092-8674) 2010 Only protein-protein interactions imex curation asher-2010-4 Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding. mouse-liver Mus musculus liver liver anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Asher G., Reinke H., Altmeyer M., Gutierrez-Arcelus M., Hottiger MO., Schibler U. Mice were sacrificed at 4 hr intervals around the clock, and liver nuclear extracts were prepared gad.asher@unige.ch Zeitgeber time (ZT) Cell (0092-8674) 2010 Only protein-protein interactions imex curation asher-2010-5 Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding. mouse-liver Mus musculus liver liver anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Asher G., Reinke H., Altmeyer M., Gutierrez-Arcelus M., Hottiger MO., Schibler U. Mice were sacrificed at 4 hr intervals around the clock, and liver nuclear extracts were prepared gad.asher@unige.ch Zeitgeber time (ZT) Cell (0092-8674) 2010 Only protein-protein interactions imex curation asher-2010-2 Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding. in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Asher G., Reinke H., Altmeyer M., Gutierrez-Arcelus M., Hottiger MO., Schibler U. Mice were sacrificed at 4 hr intervals around the clock, and liver nuclear extracts were prepared Additional information on constructs obtained from the author gad.asher@unige.ch Zeitgeber time (ZT) Cell (0092-8674) 2010 Only protein-protein interactions imex curation asher-2010-3 Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding. in vitro In vitro emsa supershift electrophoretic mobility supershift assay emsa supershift antibody detection identification by antibody antibody detection Asher G., Reinke H., Altmeyer M., Gutierrez-Arcelus M., Hottiger MO., Schibler U. Mice were sacrificed at 4 hr intervals around the clock, and liver nuclear extracts were prepared gad.asher@unige.ch Zeitgeber time (ZT) Cell (0092-8674) 2010 Only protein-protein interactions imex curation cry2_mouse Cryptochrome-2 Cry2 Kiaa0658 protein protein mouse Mus musculus Mouse MAAAAVVAATVPAQSMGADGASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQALISRMELPKKPAVAVSSQQMESCRAEIQENHDDTYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKGFPSRYIYEPWNAPESVQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPGSSQAGSISNTGPRALSSGPASPKRKLEAAEEPPGEELTKRARVTEMPTQEPASKDS clock_mouse Circadian locomoter output cycles protein kaput Clock protein protein mouse Mus musculus Mouse MVFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSMLPGNARKMDKSTVLQKSIDFLRKHKETTAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSLTPEYLKSKNQLEFCCHMLRGTIDPKEPSTYEYVRFIGNFKSLTSVSTSTHNGFEGTIQRTHRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYHQWNSRPEFIVCTHTVVSYAEVRAERRRELGIEESLPETAADKSQDSGSDNRINTVSLKEALERFDHSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRQHLPAHEKMTQRRSSFSSQSINSQSVGPSLTQPAMSQAANLPIPQGMSQFQFSAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNFGSVQLSSGNSNIQQLTPVNMQGQVVPANQVQSGHISTGQHMIQQQTLQSTSTQQSQQSVMSGHSQQTSLPSQTPSTLTAPLYNTMVISQPAAGSMVQIPSSMPQNSTQSATVTTFTQDRQIRFSQGQQLVTKLVTAPVACGAVMVPSTMLMGQVVTAYPTFATQQQQAQTLSVTQQQQQQQQQPPQQQQQQQQSSQEQQLPSVQQPAQAQLGQPPQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFPPSHHQQHQPQQQQQLPRHRTDSLTDPSKVQPQ per2_mouse Period circadian protein homolog 2 Per2 Circadian clock protein PERIOD 2 protein protein mouse Mus musculus Mouse MNGYVDFSPSPTSPTKEPGAPQPTQAVLQEDVDMSSGSSGNENCSTGRDSQGSDCDDNGKELRMLVESSNTHPSPDDAFRLMMTEAEHNPSTSGCSSEQSAKADAHKELIRTLKELKVHLPADKKAKGKASTLATLKYALRSVKQVKANEEYYQLLMSSESQPCSVDVPSYSMEQVEGITSEYIVKNADMFAVAVSLVSGKILYISNQVASIFHCKKDAFSDAKFVEFLAPHDVSVFHSYTTPYKLPPWSVCSGLDSFTQECMEEKSFFCRVSVGKHHENEIRYQPFRMTPYLVKVQEQQGAESQLCCLLLAERVHSGYEAPRIPPEKRIFTTTHTPNCLFQAVDERAVPLLGYLPQDLIETPVLVQLHPSDRPLMLAIHKKILQAGGQPFDYSPIRFRTRNGEYITLDTSWSSFINPWSRKISFIIGRHKVRVGPLNEDVFAAPPCPEEKTPHPSVQELTEQIHRLLMQPVPHSGSSGYGSLGSNGSHEHLMSQTSSSDSNGQEESHRRRSGIFKTSGKIQTKSHVSHESGGQKEASVAEMQSSPPAQVKAVTTIERDSSGASLPKASFPEELAYKNQPPCSYQQISCLDSVIRYLESCSEAATLKRKCEFPANIPSRKATVSPGLHSGEAARPSKVTSHTEVSAHLSSLTLPGKAESVVSLTSQCSYSSTIVHVGDKKPQPELETVEDMASGPESLDGAAGGLSQEKGPLQKLGLTKEVLAAHTQKEEQGFLQRFREVSRLSALQAHCQNYLQERSRAQASDRGLRNTSGLESSWKKTGKNRKLKSKRVKTRDSSESTGSGGPVSHRPPLMGLNATAWSPSDTSQSSCPSAPFPTAVPAYPLPVFQAPGIVSTPGTVVAPPAATHTGFTMPVVPMGTQPEFAVQPLPFAAPLAPVMAFMLPSYPFPPATPNLPQAFLPSQPHFPAHPTLASEITPASQAEFPSRTSTLRQPCACPVTPPAGTVALGRASPPLFQSRGSSPLQLNLLQLEEAPEGSTGAAGTLGTTGTAASGLDCTSGTSRDRQPKAPPTCNEPSDTQNSDAISTSSDLLNLLLGEDLCSATGSALSRSGASATSDSLGSSSLGFGTSQSGAGSSDTSHTSKYFGSIDSSENNHKAKMIPDTEESEQFIKYVLQDPIWLLMANTDDSIMMTYQLPSRDLQAVLKEDQEKLKLLQRSQPRFTEGQRRELREVHPWVHTGGLPTAIDVTGCVYCESEEKGNICLPYEEDSPSPGLCDTSEAKEEEGEQLTGPRIEAQT cry1_mouse Cryptochrome-1 Cry1 protein protein mouse Mus musculus Mouse MGVNAVHWFRKGLRLHDNPALKECIQGADTIRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDANLRKLNSRLFVIRGQPADVFPRLFKEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLVSKMEPLEMPADTITSDVIGKCMTPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNSNGNGGLMGYAPGENVPSCSSSGNGGLMGYAPGENVPSCSGGNCSQGSGILHYAHGDSQQTHSLKQGRSSAGTGLSSGKRPSQEEDAQSVGPKVQRQSSN bmal1_mouse Aryl hydrocarbon receptor nuclear translocator-like protein 1 Arntl Bmal1 Brain and muscle ARNT-like 1 Arnt3 protein protein mouse Mus musculus Mouse MADQRMDISSTISDFMSPGPTDLLSGSLGTSGVDCNRKRKGSATDYQLDDFAFEESMDTDKDDPHGRLEYAEHQGRIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGATNPYTEANYKPTFLSDDELKHLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKVEDKDFASTCSKKKDRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHSHMVPQPANGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDDIGHLAECHRQVLQTREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTVVLANVLEGGDPTFPQLTAPPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIAEEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIPSTGLLPGQAQETPGYPYSDSSSILGENPHIGIDMIDNDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL parp1_mouse Poly [ADP-ribose] polymerase 1 Poly[ADP-ribose] synthase 1 NAD(+) ADP-ribosyltransferase 1 Parp1 Adprp Adprt Adprt1 ADP-ribosyltransferase diphtheria toxin-like 1 DNA ADP-ribosyltransferase PARP1 Protein poly-ADP-ribosyltransferase PARP1 protein protein mouse Mus musculus Mouse MAEASERLYRVQYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGQSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVAGKGQDGSGGKAEKTLGDFAAEYAKSNRSMCKGCLEKIEKGQMRLSKKMVDPEKPQLGMIDRWYHPTCFVKKRDELGFRPEYSASQLKGFSLLSAEDKEALKKQLPAIKNEGKRKGDEVDGTDEVAKKKSRKETDKYSKLEKALKAQNELIWNIKDELKKACSTNDLKELLIFNQQQVPSGESAILDRVADGMAFGALLPCKECSGQLVFKSDAYYCTGDVTAWTKCMVKTQNPSRKEWVTPKEFREISYLKKLKVKKQDRIFPPESSAPITVHWPLSVTSAPTAVNSSAPADKPLSNMKILTLGKLSQNKDEAKAVIEKLGGKLTGSANKASLCISIKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQDLLSAHSLSPWGAEVKAEPGEVVAPRGKSAAPSKKSKGCFKEEGVNKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKESRYWIFRSWGRLGTVIGSNKLEQMPSKEEAVEQFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVKPGTKSKLPKPVQELVGMIFDVDSMKKALVEYEIDLQKMPLGKLSRRQIQAAYSILSEVQQPVSQGSSESQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEVIRKYVKNTHATTHNAYDLEVIDIFKIEREGESQRYKPFRQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLIMLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSASITLEGVEVPLGTGIPSGVNDTALLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW adp-ribose ADP-D-ribose small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) parp1_human Poly [ADP-ribose] polymerase 1 PARP1 ADPRT PPOL NAD(+) ADP-ribosyltransferase 1 Poly[ADP-ribose] synthase 1 ADP-ribosyltransferase diphtheria toxin-like 1 DNA ADP-ribosyltransferase PARP1 Protein poly-ADP-ribosyltransferase PARP1 protein protein human Homo sapiens Human MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW g-box_probe G box probe dna deoxyribonucleic acid DNA deoxyribonucleic acid dna DNA deoxyribonucleic acid chemical synthesis Chemical synthesis (Chemical synthesis) CCGCGTCGCCCTGCGCTGTCACATAGTGGAAAACGTGACCGCGCGCGCTGAGCCCGCCCCTGCG bmal1-clock-1 Zeitgeber time=0 992625 n/a 992631 unspecified role unspecified role prey prey n/a 992632 unspecified role unspecified role prey prey n/a 992633 unspecified role unspecified role prey prey n/a 992634 unspecified role unspecified role prey prey n/a 992635 unspecified role unspecified role bait bait n/a 992636 unspecified role unspecified role prey prey association association false false false 0 Figs. 3B, 3E, 4B In both wild-type and PARP-1-/- mice, immunoprecipitation of BMAL1 resulted in coimmunoprecipitation of CLOCK, indicating that the interaction between BMAL1 and CLOCK is not dependent on PARP-1 bmal1-clock-2 Zeitgeber time=4 992625 n/a 992632 unspecified role unspecified role prey prey n/a 992635 unspecified role unspecified role bait bait n/a 992634 unspecified role unspecified role prey prey association association false false false 4 Figs. 3B, 4B bmal1-clock-3 Zeitgeber time=8 992625 n/a 992635 unspecified role unspecified role bait bait n/a 992634 unspecified role unspecified role prey prey n/a 992632 unspecified role unspecified role prey prey association association false false false 8 Figs. 3B, 4B bmal1-clock-4 Zeitgeber time=12 992625 n/a 992631 unspecified role unspecified role prey prey n/a 992632 unspecified role unspecified role prey prey n/a 992634 unspecified role unspecified role prey prey n/a 992635 unspecified role unspecified role bait bait n/a 992633 unspecified role unspecified role prey prey association association false false false 12 Figs. 3B,4B bmal1-clock-5 Zeitgeber time=16 992625 n/a 992631 unspecified role unspecified role prey prey n/a 992633 unspecified role unspecified role prey prey n/a 992632 unspecified role unspecified role prey prey n/a 992634 unspecified role unspecified role prey prey n/a 992635 unspecified role unspecified role bait bait association association false false false 16 Figs. 3B, 4B bmal1-clock-6 Zeitgeber time=20 992625 n/a 992633 unspecified role unspecified role prey prey n/a 992631 unspecified role unspecified role prey prey n/a 992632 unspecified role unspecified role prey prey n/a 992635 unspecified role unspecified role bait bait n/a 992634 unspecified role unspecified role prey prey association association false false false 20 Figs. 3B, 4B parp1-bmal1-6 Zeitgeber time=8 992625 n/a 992635 unspecified role unspecified role prey prey n/a 992636 unspecified role unspecified role bait bait physical association physical association false false false 8 Fig. 3C adp-ribose-clock Zeitgeber time=4 992626 n/a 992636 unspecified role unspecified role prey prey n/a 992632 unspecified role unspecified role prey prey n/a 992637 unspecified role unspecified role bait bait association association false false false 4 Interaction between ADP-ribose and Clock observed in parp1 -/- cells. Clock remained associated with ADP-ribose even under harsh denaturing conditions (1% SDS) which removed PARP1 Figs. 3G, Supp. Fig. 4 adp_ribose-clock Zeitgeber time=0 992626 n/a 992637 unspecified role unspecified role bait bait n/a 992632 unspecified role unspecified role prey prey physical association physical association false false false 0 Figs. 3I adp_ribose-clock-1 Zeitgeber time=4 992626 n/a 992637 unspecified role unspecified role bait bait n/a 992632 unspecified role unspecified role prey prey physical association physical association false false false 4 Figs. 3I adp_ribose-clock-2 Zeitgeber time=8 992626 n/a 992637 unspecified role unspecified role bait bait n/a 992632 unspecified role unspecified role prey prey physical association physical association false false false 8 Figs. 3I adp_ribose-clock-3 Zeitgeber time=12 992626 n/a 992637 unspecified role unspecified role bait bait n/a 992632 unspecified role unspecified role prey prey physical association physical association false false false 12 Figs. 3I adp_ribose-clock-4 Zeitgeber time=16 992626 n/a 992637 unspecified role unspecified role bait bait n/a 992632 unspecified role unspecified role prey prey physical association physical association false false false 16 Figs. 3I adp_ribose-clock-5 Zeitgeber time=20 992626 n/a 992637 unspecified role unspecified role bait bait n/a 992632 unspecified role unspecified role prey prey physical association physical association false false false 20 Figs. 3I parp1-bmal1-1 Zeitgeber time=0 992627 n/a 992636 unspecified role unspecified role bait bait n/a 992632 unspecified role unspecified role prey prey n/a 992635 unspecified role unspecified role prey prey association association false false false 0 Fig. 3C parp1-bmal1-2 Zeitgeber time=4 992627 n/a 992636 unspecified role unspecified role bait bait n/a 992632 unspecified role unspecified role prey prey n/a 992635 unspecified role unspecified role prey prey association association false false false 4 Fig. 3C parp1-bmal1-3 Zeitgeber time=12 992627 n/a 992636 unspecified role unspecified role bait bait n/a 992635 unspecified role unspecified role prey prey physical association physical association false false false 12 Fig. 3C parp1-bmal1-4 Zeitgeber time=16 992627 n/a 992636 unspecified role unspecified role bait bait n/a 992635 unspecified role unspecified role prey prey physical association physical association false false false 16 Fig. 3C parp1-bmal1-5 Zeitgeber time=20 992627 n/a 992636 unspecified role unspecified role bait bait n/a 992635 unspecified role unspecified role prey prey physical association physical association false false false 20 Fig. 3C clock-bmal1-1 Zeitgeber time=4 992628 n/a 992632 unspecified role unspecified role bait bait n/a 992636 unspecified role unspecified role prey prey n/a 992635 unspecified role unspecified role prey prey association association false false false 4 Fig. 3D clock-bmal1-2 Zeitgeber time=16 992628 n/a 992633 unspecified role unspecified role prey prey n/a 992635 unspecified role unspecified role prey prey n/a 992632 unspecified role unspecified role bait bait association association false false false 16 Fig. 3D parp1-clock-1 992629 n/a 992638 unspecified role unspecified role bait bait region his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false region ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false spofr-sf_21 Spodoptera frugiperda insect cells sf_21 Insect cells derived from immature ovaries of fall armyworm Spodoptera frugiperda pupae. full name: IPLB-SF-21-AE cells are susceptible to Baculovirus infection. n/a 992632 unspecified role unspecified role prey prey direct interaction direct interaction false false false Fig. 3F g-box-bmal1 DNA binding of BMAL1 992630 n/a 992639 unspecified role unspecified role bait bait n/a 992635 unspecified role unspecified role prey prey mouse-liver Mus musculus liver liver physical association physical association false false false G-box probe is radio-labelled. Supp. Fig. 5C