IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ holzel-2005-1 Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation. human-u2-os Human U2-OS osteosarcoma cell line u2-os U2-OS osteocaroma cell line Not in CAPRI and no primary literature reference anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Holzel M., Rohrmoser M., Schlee M., Grimm T., Harasim T., Malamoussi A., Gruber-Eber A., Kremmer E., Hiddemann W., Bornkamm GW., Eick D. eick@gsf.de J. Cell Biol. (0021-9525) 2005 Only protein-protein interactions imex curation holzel-2005-2 Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation. human-u2-os Human U2-OS osteosarcoma cell line u2-os U2-OS osteocaroma cell line Not in CAPRI and no primary literature reference comig non denat gel comigration in non denaturing gel electrophoresis comig non denat gel western blot western blot Immuno blot Immuno blot Holzel M., Rohrmoser M., Schlee M., Grimm T., Harasim T., Malamoussi A., Gruber-Eber A., Kremmer E., Hiddemann W., Bornkamm GW., Eick D. Total cell lysates of U2OS cells were separated by native gel electrophoresis, followed by a second denaturing gel electrophoresis. eick@gsf.de J. Cell Biol. (0021-9525) 2005 Only protein-protein interactions imex curation pesc_human Pescadillo homolog PES1 protein protein human Homo sapiens Human MGGLEKKKYERGSATNYITRNKARKKLQLSLADFRRLCILKGIYPHEPKHKKKVNKGSTAARTFYLIKDIRFLLHEPIVNKFREYKVFVRKLRKAYGKSEWNTVERLKDNKPNYKLDHIIKERYPTFIDALRDLDDALSMCFLFSTFPRTGKCHVQTIQLCRRLTVEFMHYIIAARALRKVFLSIKGIYYQAEVLGQPIVWITPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQLLNLHYPPKLEGQAQAEAKAGEGTYALDSESCMEKLAALSASLARVVVPATEEEAEVDEFPTDGEMSAQEEDRRKELEAQEKHKKLFEGLKFFLNREVPREALAFIIRSFGGEVSWDKSLCIGATYDVTDSRITHQIVDRPGQQTSVIGRCYVQPQWVFDSVNARLLLPVAEYFSGVQLPPHLSPFVTEKEGDYVPPEKLKLLALQRGEDPGNLNESEEEEEEDDNNEGDGDEEGENEEEEEDAEAGSEKEEEARLAALEEQRMEGKKPRVMAGTLKLEDKQRLAQEEESEAKRLAIMMMKKREKYLYQKIMFGKRRKIREANKLAEKRKAHDEAVRSEKKAKKARPE bop1_human Ribosome biogenesis protein BOP1 Block of proliferation 1 protein BOP1 KIAA0124 protein protein human Homo sapiens Human MAGSRGAGRTAAPSVRPEKRRSEPELEPEPEPEPPLLCTSPLSHSTGSDSGVSDSEESVFSGLEDSGSDSSEDDDEGDEEGEDGALDDEGHSGIKKTTEEQVQASTPCPRTEMASARIGDEYAEDSSDEEDIRNTVGNVPLEWYDDFPHVGYDLDGRRIYKPLRTRDELDQFLDKMDDPDYWRTVQDPMTGRDLRLTDEQVALVRRLQSGQFGDVGFNPYEPAVDFFSGDVMIHPVTNRPADKRSFIPSLVEKEKVSRMVHAIKMGWIQPRRPRDPTPSFYDLWAQEDPNAVLGRHKMHVPAPKLALPGHAESYNPPPEYLLSEEERLAWEQQEPGERKLSFLPRKFPSLRAVPAYGRFIQERFERCLDLYLCPRQRKMRVNVDPEDLIPKLPRPRDLQPFPTCQALVYRGHSDLVRCLSVSPGGQWLVSGSDDGSLRLWEVATARCVRTVPVGGVVKSVAWNPSPAVCLVAAAVEDSVLLLNPALGDRLVAGSTDQLLSAFVPPEEPPLQPARWLEASEEERQVGLRLRICHGKPVTQVTWHGRGDYLAVVLATQGHTQVLIHQLSRRRSQSPFRRSHGQVQRVAFHPARPFLLVASQRSVRLYHLLRQELTKKLMPNCKWVSSLAVHPAGDNVICGSYDSKLVWFDLDLSTKPYRMLRHHKKALRAVAFHPRYPLFASGSDDGSVIVCHGMVYNDLLQNPLLVPVKVLKGHVLTRDLGVLDVIFHPTQPWVFSSGADGTVRLFT wdr12_human Ribosome biogenesis protein WDR12 WDR12 WD repeat-containing protein 12 protein protein human Homo sapiens Human MAQLQTRFYTDNKKYAVDDVPFSIPAASEIADLSNIINKLLKDKNEFHKHVEFDFLIKGQFLRMPLDKHMEMENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILTGSYDKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIVTLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA bop1-pesc-1 Interaction between BOP1 and PESC demonstrated by coimmunoprecipitation 865170 n/a 865172 unspecified role unspecified role bait bait n/a 865173 unspecified role unspecified role prey prey association association false false false Fig. 7A wdr12-bop1-1 Interaction between WDR12 and BOP1 identified by coimmunoprecipitation 865170 n/a 865174 unspecified role unspecified role prey prey n/a 865173 unspecified role unspecified role bait bait association association false false false Fig. 7A wdr12-pesc-1 Interaction between WDR12 and PESC identified by coimmunoprecipitation 865170 n/a 865172 unspecified role unspecified role prey prey n/a 865174 unspecified role unspecified role bait bait association association false false false Fig. 7A bop1-pesc-2 Interaction between BOP1 and PESC demonstrated by coimmunoprecipitation 865170 n/a 865172 unspecified role unspecified role prey prey n/a 865173 unspecified role unspecified role bait bait association association false false false Fig. 7A wdr12-pesc-2 Interaction between WDR12 and PESC identified by coimmunoprecipitation 865170 n/a 865172 unspecified role unspecified role bait bait n/a 865174 unspecified role unspecified role prey prey association association false false false Fig. 7 wdr12-bop1-2 Interaction between WDR12 and BOP1 identified by coimmunoprecipitation 865170 n/a 865174 unspecified role unspecified role bait bait n/a 865173 unspecified role unspecified role prey prey association association false false false Fig. 7A wdr12-pesc-3 Interaction between WDR12, BOP1 and PESC identified by coimmunoprecipitation 865171 n/a 865172 unspecified role unspecified role neutral component neutral component n/a 865173 unspecified role unspecified role neutral component neutral component n/a 865174 unspecified role unspecified role neutral component neutral component association association false false false Fig. 7B