IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ azem-1995-1 The protein-folding activity of chaperonins correlates with the symmetric GroEL14(GroES7)2 heterooligomer. in vitro In vitro crosslink cross-linking study crosslink weight by staining molecular weight estimation by staining weight by staining Azem A., Diamant S., Kessel M., Weiss C., Goloubinoff P. Due to the better resolution on SDS gels of the intermediate crosslinking species GroEL7 and GroEL7GroES7, as compared to the poor resolution of the final crosslinking products of GroEL14GroES7 and GroEL14(GroES7)2, the fraction of GroEL14GroES7 and GroEL14(GroES7)2 particles in a chaperonin solution was determined from the ratio of crosslinked species GroEL7 and GroEL7GroES7. Proc. Natl. Acad. Sci. U.S.A. (0027-8424) 1995 Only protein-protein interactions imex curation ch60_ecoli Chaperonin GroEL groEL 60 kDa chaperonin Chaperonin-60 GroEL protein groL mopA JW4103 b4143 protein protein ecoli Escherichia coli (strain K12) MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM CD3A0FB505F74AD1 ch10_ecoli Co-chaperonin GroES groES 10 kDa chaperonin Chaperonin-10 groS mopB JW4102 b4142 protein protein ecoli Escherichia coli (strain K12) MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVGNGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA 76829E09B11217EF groes-groel 781788 n/a 781789 unspecified role unspecified role neutral component neutral component Stoichiometry: 1.0 n/a 781790 unspecified role unspecified role neutral component neutral component Stoichiometry: 1.0 association association false false false 1A, B and Table 1 Oligomers formed. groel-groel 781788 n/a 781789 unspecified role unspecified role neutral component neutral component Stoichiometry: 1.0 n/a 781789 unspecified role unspecified role neutral component neutral component Stoichiometry: 1.0 association association false false false 1A, B and Table 1 Oligomers formed. groes-groel-1 781788 n/a 781789 unspecified role unspecified role neutral component neutral component Stoichiometry: 1.0 n/a 781790 unspecified role unspecified role neutral component neutral component Stoichiometry: 2.0 association association false false false 1A, B, 3 and Table 1 Oligomers formed. ATP regeneration system gives more samples in a 2:1 ratio of gro ES to GRO EL. The ADP acts as a uncoupling agent.