MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it http://mint.bio.uniroma2.it/mint conners-2008-5 The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled-coil. in vitro In vitro elisa enzyme linked immunosorbent assay ELISA ELISA elisa predetermined predetermined participant predetermined Conners R., Hill DJ., Borodina E., Agnew C., Daniell SJ., Burton NM., Sessions RB., Clarke AR., Catto LE., Lammie D., Wess T., Brady RL., Virji M. EMBO J. (0261-4189) 2008 2008-11-28 Only protein-protein interactions imex curation conners-2008-6 The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled-coil. in vitro In vitro far western blotting far western blotting Affinity blotting Affinity blotting predetermined predetermined participant predetermined Conners R., Hill DJ., Borodina E., Agnew C., Daniell SJ., Burton NM., Sessions RB., Clarke AR., Catto LE., Lammie D., Wess T., Brady RL., Virji M. EMBO J. (0261-4189) 2008 2008-11-28 Only protein-protein interactions imex curation conners-2008-1 The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled-coil. in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Conners R., Hill DJ., Borodina E., Agnew C., Daniell SJ., Burton NM., Sessions RB., Clarke AR., Catto LE., Lammie D., Wess T., Brady RL., Virji M. EMBO J. (0261-4189) 2008 2008-11-28 Only protein-protein interactions imex curation conners-2008-2 The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled-coil. in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Conners R., Hill DJ., Borodina E., Agnew C., Daniell SJ., Burton NM., Sessions RB., Clarke AR., Catto LE., Lammie D., Wess T., Brady RL., Virji M. EMBO J. (0261-4189) 2008 2008-11-28 Only protein-protein interactions imex curation conners-2008-3 The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled-coil. in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Conners R., Hill DJ., Borodina E., Agnew C., Daniell SJ., Burton NM., Sessions RB., Clarke AR., Catto LE., Lammie D., Wess T., Brady RL., Virji M. EMBO J. (0261-4189) 2008 2008-11-28 Only protein-protein interactions imex curation conners-2008-4 The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled-coil. in vitro In vitro solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Conners R., Hill DJ., Borodina E., Agnew C., Daniell SJ., Burton NM., Sessions RB., Clarke AR., Catto LE., Lammie D., Wess T., Brady RL., Virji M. EMBO J. (0261-4189) 2008 2008-11-28 Only protein-protein interactions imex curation conners-2008-7 The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled-coil. in vitro In vitro saxs x ray scattering saxs predetermined predetermined participant predetermined Conners R., Hill DJ., Borodina E., Agnew C., Daniell SJ., Burton NM., Sessions RB., Clarke AR., Catto LE., Lammie D., Wess T., Brady RL., Virji M. EMBO J. (0261-4189) 2008 2008-11-28 Only protein-protein interactions imex curation q8gh87_morca uspa1 protein protein morca Moraxella catarrhalis MNKIYKVKKNAAGHLVACSEFAKGHTKKAVLGSLLIVGILGMATTASAQAINTGQGTVVDQNGNEAIGNYSTASGGDYNQAKGNYSTASGGSGNTAEGNYSTASGGLGNTAEGNYSTASGGLGNTAKGKYSTVAGGANNQAKGDYSTASGGSGNTAEGNYSTVAGGKNNQATGLNSTVAGGSDNQATGTGSFAAGVGNKANAENAVALGNKNTIEGENSVAIGSNNTVETGKENVFILGSGTTGVTSNSVLLGNKTAGKEATAVNDATVNGLTLKNFAGVSKTGNGTVSVGSENHERQIVNVGAGKISADSTDAVNGSQLHALATVVAKNKSDITKNQAETLVNRVNIKELERKQENDIKEVVEMQNAIAEQADKNKNHIQDLAKAQLAGVTVMEELNKHVEDLYEATNDNLDKISQLDGAVFNNTQNIAKNSNHIKTLENNVEEELLNLSGRLLDQKADIDNNINNIYELAQQQDQHSSDIKTLKNNVEEGLLDLSGRLIDQKADLTKDIKALENNVEEGLLDLSGRLIDQKADIAKNQADIAQNQTDIQDLAAYNELQDAYAKQQTEAIDALNKASSANTDRIATAELGIAENKKDAQIAKAQANENKDGIAKNQADIQLHDKKITNLGILHSMVARAVGNNTQGVATNKADIAKNQADIANNIKNIYELAQQQDQHSSDIKTLAKVSAANTDRIAKNKAEADASFETLTKNQNTLIEQGEALVEQNKAINQELEGFAAHADVQDKQILQNQADITTNKTAIEQNINRTVANGFEIEKNKAGIATNKQELILQNDRLNRINETNNRQDQKIDQLGYALKEQGQHFNNRISAVERQTAGGIANAIAIATLPSPSRAGEHHVLFGSGYHNGQAAVSLGAAGLSDTGKSTYKIGLSWSDAGGLSGGVGGSYRWK mint ceam1_human Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 BGP BGP1 Biliary glycoprotein 1 protein protein human Homo sapiens Human MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGRASDQRDLTEHKPSVSNHTQDHSNDPPNKMNEVTYSTLNFEAQQPTQPTSASPSLTATEIIYSEVKKQ uspa1-ceacam1-1 774453 q8gh87_morca uspa1 774460 predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified undefined mutation mutation disrupting interaction mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ceam1_human N-CEACAM1 774461 predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified direct interaction direct interaction false false false f5c mint uspa1-ceacam1-2 774453 q8gh87_morca uspa1 774460 predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified undefined mutation mutation disrupting interaction mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ceam1_human N-CEACAM1 774461 predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified direct interaction direct interaction false false false f5c mint uspa1-ceacam1-3 774453 q8gh87_morca uspa1 774460 predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified undefined mutation mutation disrupting interaction mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ceam1_human N-CEACAM1 774461 predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified direct interaction direct interaction false false false f5c mint uspa1-ceacam1-4 774453 q8gh87_morca uspa1 774460 predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified undefined mutation mutation disrupting interaction mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false undefined mutation mutation disrupting interaction mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ceam1_human N-CEACAM1 774461 predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified direct interaction direct interaction false false false f5c mint uspa1-ceacam1-5 774454 q8gh87_morca uspa1 774460 predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false undefined mutation mutation disrupting interaction mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false ceam1_human N-CEACAM1 774461 western blot western blot Immuno blot Immuno blot unspecified role unspecified role prey prey purified purified direct interaction direct interaction false false false f5c mint uspa1-ceacam1-6 774454 q8gh87_morca uspa1 774460 predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false undefined mutation mutation disrupting interaction mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false ceam1_human N-CEACAM1 774461 western blot western blot Immuno blot Immuno blot unspecified role unspecified role prey prey purified purified direct interaction direct interaction false false false f5c mint uspa1-ceacam1-7 774454 q8gh87_morca uspa1 774460 predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false undefined mutation mutation disrupting interaction mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false undefined mutation mutation disrupting interaction mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false ceam1_human N-CEACAM1 774461 western blot western blot Immuno blot Immuno blot unspecified role unspecified role prey prey purified purified direct interaction direct interaction false false false f5c mint uspa1-ceacam1-8 774454 q8gh87_morca uspa1 774460 predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false undefined mutation mutation disrupting interaction mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain false ceam1_human N-CEACAM1 774461 western blot western blot Immuno blot Immuno blot unspecified role unspecified role prey prey purified purified direct interaction direct interaction false false false f5c mint uspa1 774455 q8gh87_morca uspa1 774460 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false Stoichiometry: 3.0 direct interaction direct interaction false false false f2 mint ceacam1-uspa1 774456 q8gh87_morca uspa1 774460 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ceam1_human N-CEACAM1 774461 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified direct interaction direct interaction false false false f4a mint uspa1-ceacam1 774457 q8gh87_morca uspa1 774460 predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ceam1_human N-CEACAM1 774461 predetermined predetermined participant predetermined unspecified role unspecified role prey prey purified purified direct interaction direct interaction false false false 774457 f4c mint ceacam1-uspa1-1 774458 q8gh87_morca uspa1 774460 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ceam1_human N-CEACAM1 774461 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified direct interaction direct interaction false false false f4b mint ceacam1-uspa1-2 774459 q8gh87_morca uspa1 774460 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain false ceam1_human N-CEACAM1 774461 predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified direct interaction direct interaction false false false f6 mint