IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ http://www.ebi.ac.uk/ yeh-2008-2 Regulation of a late phase of T cell polarity and effector functions by Crtam. mouse-t-cell Mouse T cell t-cell Peripheral blood T-lymphocytes confocal microscopy confocal microscopy immunostaining immunostaining Yeh JH., Sidhu SS., Chan AC. acc@gene.com Cell (0092-8674) 2008 Only protein-protein interactions 9 imex curation yeh-2008-4 Regulation of a late phase of T cell polarity and effector functions by Crtam. mouse-t-cell Mouse T cell t-cell Peripheral blood T-lymphocytes confocal microscopy confocal microscopy immunostaining immunostaining Yeh JH., Sidhu SS., Chan AC. naive CD4+ T cells acc@gene.com Cell (0092-8674) 2008 Only protein-protein interactions 9 imex curation yeh-2008-1 Regulation of a late phase of T cell polarity and effector functions by Crtam. mouse-t-cell Mouse T cell t-cell Peripheral blood T-lymphocytes anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Yeh JH., Sidhu SS., Chan AC. acc@gene.com Cell (0092-8674) 2008 Only protein-protein interactions 9 imex curation yeh-2008-3 Regulation of a late phase of T cell polarity and effector functions by Crtam. in vitro In vitro anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Yeh JH., Sidhu SS., Chan AC. acc@gene.com Cell (0092-8674) 2008 Only protein-protein interactions 9 imex curation crtam_mouse Cytotoxic and regulatory T-cell molecule Crtam Class-I MHC-restricted T-cell-associated molecule protein protein mouse Mus musculus Mouse MWWGALSLLFWVPVQAAFLKMETVTVEEGQTLTLTCVTSQTKNVSLQWLAPSGFTIFLNQHPALKSSKYQLLHHSATQLSISVSNVTLREEGVYTCLHYGSSVKTKQVRVTVLVTPFQPTVEALVLRRQNGEKSVVLKCSTERSKPPPQITWLLGEGLEIYGELNHEFEADGKICNTSSMLIARAYGKNSTVHCIIQHEGLHGRKLVAPFQFEDLVADQETSDQETSDAPEQSSLSSQALQQPTSTVSMMENSSIPETDKEEKEHATQDPGLSTEASAQHTGLARRKSGILLLTLVSFLIFILFIIVQLFIMKLRKAHVVWKKESEISEQALESYRSRSNNEETSSQENSSQAPQSKRCMNYITRLYSGAKTKKSAQHWKLGGKHSRVPESIV scrib_mouse Protein scribble homolog Scrib Kiaa0147 Lap4 Scrib1 Protein LAP4 protein protein mouse Mus musculus Mouse MLKCIPLWRCNRHVESVDKRHCSLQVVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPVELGGLALLTDLLLSQNLLQRLPEGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLLTALPHSLGKLTKLTNLNVDRNHLEVLPPEIGGCVALSVLSLRDNRLAVLPPELAHTAELHVLDVAGNRLRSLPFALTHLNLKALWLAENQAQPMLRFQTEDDAQTGEKVLTCYLLPQQPLPSLEDAGQQSSPSESCSDAPLSRVSVIQFEDTLEGEEDAEEAAAEKRGLQRRATPHPSELKVMKRGIEERRNEAFVCKPDPSPPSPSEEEKRLSAESALSGGSVPSASTASEGEPEILPAEVQGLGQHEAMPAQEEYTEDDYNEPTVHFAEDTLIPREDGESEEGQPEAAWPLPSGRQRLIRKDTPHYKKHFKISKLPQPEAVVALLQGVQTDREGPTAGWHNGPHTPWAPRAHEEEEEEEEENRDEEEGEATTEEDDKEEAVASAPSVKGVSFDQANNLLIEPARIEEEELTLTIVRQTGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAARAGVRVGDKLLEVNGVALQDAEHHEAVEALRGAGAAVQMRVWRERMVEPENAVTITPLRPEDDYSPREWRGGGLRLPLLQPETPVSLRQRHAACLVRSEKGLGFSIAGGKGSTPYRAGDGGIFISRIAEGGAAHRAGTLQVGDRVLSINGVDMTEARHDHAVSLLTAASPTISLLLERETGGTYPPSPPPHSSPTPAATVAATVSTAVPGEPLLPRLSPSLLATALEGPYPVEEICLPRAGGPLGLSIVGGSDHSSHPFGVQDPGVFISKVLPRGLAARCGLRVGDRILAVNGQDVREATHQEAVSALLRPCLELCLLVRRDPPPPGMRELCIQKAPGEKLGISIRGGAKGHAGNPCDPTDEGIFISKVSPTGAAGRDGRLRVGLRLLEVNQQSLLGLTHAEAVQLLRSVGDTLTVLVCDGFDTSTTTALEVSPGVIANPFAAGLGHRNSLESISSIDRELSPEGPGKEKELASQALPWESESAETTGRNLEPLKLDYRALAALPSAGSLQRGPSATTGGKTTEAPCSPGSQQPPSPDELPANVKQAYRAFAAVPTVHPPENSATQPPTPGPAASPEQLSFRERQKYFELEVRVPQAEGPPKRVSLVGADDLRKMQEEEARKLQQKRAQMLREEAVTSGPDMGLASDRESPDDQQEAEQPWAVPSHAGGSSPSSPPPLGGNAPVRTAKAERRHQERLRMQSPELPAPERALSPAERRALEAEKRALWRAARMKSLEQDALRAQMVLSKSQEGRGKRGPLERLAEAPSPAPTPSPTPLEDFGLQTSASPGRLSPDFVEELRTLEASPSPGSQEEDGEVALVLLGRPSPGAVGPEDMTLCSSRRSVRPGRRGLGPVPS cdc42_mouse Cell division control protein 42 homolog Cdc42 G25K GTP-binding protein protein protein mouse Mus musculus Mouse MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL kpcd_mouse Protein kinase C delta type nPKC-delta Tyrosine-protein kinase PRKCD Prkcd Pkcd protein protein mouse Mus musculus Mouse MAPFLRISFNSYELGSLQVEDEASQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKTTFDAHIYEGRVIQIVLMRAAEDPVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMCVQYFLEDGDCKQSMRSEEEAKFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKEFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTATNSRDTIFQKERFNIDMPHRFKVYNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQRSSRKLDTTESVGIYQGFEKKPEVSGSDILDNNGTYGKIWEGSTRCTLENFTFQKVLGKGSFGKVLLAELKGKDKYFAIKCLKKDVVLIDDDVECTMVEKRVLALAWESPFLTHLICTFQTKDHLFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLHSKGIIYRDLKLDNVMLDRDGHIKIADFGMCKENIFGEGRASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIMEKLFERDPDKRLGVTGNIRIHPFFKTINWSLLEKRKVEPPFKPKVKSPSDYSNFDPEFLNEKPQLSFSDKNLIDSMDQEAFHGFSFVNPKFEQFLDI scrib-crtam-2 Colocalisation of Scrib and Crtam 733150 N/A 733154 unspecified role unspecified role neutral component neutral component N/A 733155 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Anti-CD3/28(10:2 ug/ml) mAbs for 14 hours. Fig. 4B scrib-cdc42-1 Colocalisation of Scrib and Cdc42 733150 N/A 733155 unspecified role unspecified role neutral component neutral component N/A 733156 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Anti-CD3/28(10:2 ug/ml) mAbs for 14 hours. Fig. 4C Cocalisation requires the presence of Ctram scrib-prkcd-1 Colocalisation of Scrib and Prkcd 733150 N/A 733157 unspecified role unspecified role neutral component neutral component N/A 733155 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Anti-CD3/28(10:2 ug/ml) mAbs for 14 hours. Fig. 4D Cocalisation requires the presence of Ctram scrib-tln1-1 Colocalisation of Scrib and Tln1 733150 N/A 733155 unspecified role unspecified role neutral component neutral component N/A 733156 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Anti-CD3/28(10:2 ug/ml) mAbs for 14 hours. Fig. 4C Cocalisation requires the presence of Ctram scrib-crtam-4 Colocalisation of Scrib and Crtam 733151 N/A 733155 unspecified role unspecified role neutral component neutral component N/A 733154 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false OVA peptide Supp. Fig. 10A scrib-prkcd-2 Colocalisation of Scrib and Prkcd 733151 N/A 733155 unspecified role unspecified role neutral component neutral component N/A 733157 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false OVA peptide Supp. Fig. 10C scrib-cdc42-2 Colocalisation of Scrib and Cdc42 733151 N/A 733156 unspecified role unspecified role neutral component neutral component N/A 733155 unspecified role unspecified role neutral component neutral component colocalization colocalization false false false Supp. Fig. 10B Cocalisation requires the presence of Ctram OVA peptide scrib-crtam-1 Interaction between Scrib and Crtam demonstrated by coimmunoprecipitation 733152 N/A 733155 unspecified role unspecified role bait bait N/A 733154 unspecified role unspecified role prey prey physical association physical association false false false Anti-CD3/28(10:2 ug/ml) mAbs for 14 hours. Fig. 4A scrib-crtam-3 Interaction between Scrib and Crtam demonstrated by coimmunoprecipitation 733153 N/A 733155 unspecified role unspecified role prey prey pdz3 region sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis range range range range false N/A 733154 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined false human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. physical association physical association false false false Supp. Fig. 9A