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    <entry>
        <source releaseDate="2007-11-23Z">
            <names>
                <shortLabel>UniProt</shortLabel>
                <fullName>UniProt</fullName>
            </names>
            <xref>
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            </xref>
            <attributeList>
                <attribute name="url" nameAc="MI:0614">http://www.uniprot.org</attribute>
            </attributeList>
        </source>
        <experimentList>
            <experimentDescription id="678388">
                <names>
                    <shortLabel>cooper-2000a-1</shortLabel>
                    <fullName>Ama1p is a meiosis-specific regulator of the anaphase promoting complex/cyclosome in yeast.</fullName>
                </names>
                <bibref>
                    <xref>
                        <primaryRef db="pubmed" dbAc="MI:0446" id="11114178" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </bibref>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1553697" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-19991" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <hostOrganismList>
                    <hostOrganism ncbiTaxId="4932">
                        <names>
                            <shortLabel>yeasx</shortLabel>
                            <fullName>Saccharomyces cerevisiae (Baker's yeast)</fullName>
                            <alias typeAc="MI:1041" type="synonym">Baker's yeast</alias>
                        </names>
                    </hostOrganism>
                </hostOrganismList>
                <interactionDetectionMethod>
                    <names>
                        <shortLabel>anti tag coip</shortLabel>
                        <fullName>anti tag coimmunoprecipitation</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti tag coip</alias>
                    </names>
                    <xref>
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                    </xref>
                </interactionDetectionMethod>
                <participantIdentificationMethod>
                    <names>
                        <shortLabel>anti tag western</shortLabel>
                        <fullName>anti tag western blot</fullName>
                        <alias typeAc="MI:1041" type="synonym">anti tag western</alias>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0705" refType="identity" refTypeAc="MI:0356"/>
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                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                    </xref>
                </participantIdentificationMethod>
                <attributeList>
                    <attribute name="author-list" nameAc="MI:0636">Cooper KF., Mallory MJ., Egeland DB., Jarnik M., Strich R.</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">R_Strich@fccc.edu</attribute>
                    <attribute name="contact-email" nameAc="MI:0634">R.Strich@fccc.edu</attribute>
                    <attribute name="journal" nameAc="MI:0885">Proc. Natl. Acad. Sci. U.S.A. (0027-8424)</attribute>
                    <attribute name="publication year" nameAc="MI:0886">2000</attribute>
                    <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
                    <attribute name="imex curation" nameAc="MI:0959"/>
                    <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
                </attributeList>
            </experimentDescription>
        </experimentList>
        <interactorList>
            <interactor id="678389">
                <names>
                    <shortLabel>ama1_yeast</shortLabel>
                    <fullName>Meiosis-specific APC/C activator protein AMA1</fullName>
                    <alias typeAc="MI:0301" type="gene name">AMA1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">SPO70</alias>
                    <alias typeAc="MI:0305" type="locus name">YGR225W</alias>
                    <alias typeAc="MI:0306" type="orf name">G8541</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Activator of meiotic APC/C protein 1</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Sporulation-specific protein 70</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P50082" version="SP_45" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q96VQ3" version="SP_45" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_011741.5"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005680" secondary="anaphase-promoting complex" version="SP_162"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015943" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0030476" secondary="ascospore wall assembly" version="SP_162"/>
                    <secondaryRef db="ensemblfungi" id="YGR225W" version="SP_162" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1904668" secondary="positive regulation of ubiquitin protein ligase activity" version="SP_162"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001680" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031145" secondary="anaphase-promoting complex-dependent catabolic process" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045732" secondary="positive regulation of protein catabolic process" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1903024" secondary="positive regulation of ascospore-type prospore membrane formation" version="SP_162"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D6VV07" version="SP_73" refType="secondary-ac" refTypeAc="MI:0360"/>
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                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-7218N"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:1905786" secondary="positive regulation of anaphase-promoting complex-dependent catabolic process" version="SP_162"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045132" secondary="meiotic chromosome segregation" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0010997" secondary="anaphase-promoting complex binding" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0007127" secondary="meiosis I" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0006508" secondary="proteolysis" version="SP_162"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR033010" version="SP_162"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0044778" secondary="meiotic DNA integrity checkpoint signaling" version="SP_162"/>
                </xref>
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                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
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                    </xref>
                </interactorType>
                <organism ncbiTaxId="559292">
                    <names>
                        <shortLabel>yeast</shortLabel>
                        <fullName>Saccharomyces cerevisiae</fullName>
                        <alias typeAc="MI:1041" type="synonym">Baker's yeast</alias>
                    </names>
                </organism>
                <sequence>MATPHLYHRYNSKSSNKNINSSGNSTEVDRFIPKSVSRNAYKSIPMLNGFDISYSELCEKSPSPERLSSPEFFNELRNTGHYESISTTNEFSMSSISSSSESQVTRSGSARASRNDYSKLTKEQKDHRKNIAHSLGFQLPDRVFTFETTSAEILEKNKAIKNCFGPGSCAEIRSTFDFSTLSPDVARYYIANSNARSASPQRQIQRPAKRVKSHIPYRVLDAPCLRNDFYSNLISWSRTTNNVLVGLGCSVYIWSEKEGAVSILDHQYLSEKRDLVTCVSFCPYNTYFIVGTKFGRILLYDQKEFFHSSNTNEKEPVFVFQTESFKGICCLEWFKPGEICKFYVGEENGNVSLFEIKSLHFPIKNWSKRQKLEDENLIGLKLHSTYQAQAQQVCGISLNEHANLLAVGGNDNSCSLWDISDLDKPIKKFVLPHKAAVKAIAFCPWSKSLLATGGGSKDRCIKFWHTSTGTLLDEICTSGQVTSLIWSLRHKQIVATFGFGDTKNPVLITLYSYPKLSKLLEVRSPNPLRVLSAVISPSSMAICVATNDETIRFYELWNDKEEIINEIQESGIYGSNIIEYMEGIETTHNKRIR</sequence>
            </interactor>
            <interactor id="678390">
                <names>
                    <shortLabel>cdc16_yeast</shortLabel>
                    <fullName>Anaphase-promoting complex subunit CDC16</fullName>
                    <alias typeAc="MI:0301" type="gene name">CDC16</alias>
                    <alias typeAc="MI:0305" type="locus name">YKL022C</alias>
                    <alias typeAc="MI:0302" type="gene name synonym">Cell division control protein 16</alias>
                </names>
                <xref>
                    <primaryRef db="uniprotkb" dbAc="MI:0486" id="P09798" version="SP_76" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="refseq" dbAc="MI:0481" id="NP_012903.1"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0031145" secondary="anaphase-promoting complex-dependent catabolic process" version="SP_205"/>
                    <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-983168" version="SP_205"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-4208" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D6VXR3" version="SP_111" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0045842" secondary="positive regulation of mitotic metaphase/anaphase transition" version="SP_205"/>
                    <secondaryRef db="ensemblfungi" id="YKL022C_mRNA" version="SP_205" refType="transcript"/>
                    <secondaryRef db="ensemblfungi" id="YKL022C" version="SP_205" refType="identity" refTypeAc="MI:0356"/>
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                    <secondaryRef db="sgd" dbAc="MI:0484" id="S000001505"/>
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                    <secondaryRef db="ensemblfungi" id="YKL022C" version="SP_205" refType="gene"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0051301" secondary="cell division" version="SP_205"/>
                    <secondaryRef db="mint" dbAc="MI:0471" id="P09798"/>
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                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013105" version="SP_205"/>
                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" secondary="cytosol" version="SP_205"/>
                    <secondaryRef db="interpro" dbAc="MI:0449" id="IPR019734" version="SP_205"/>
                    <secondaryRef db="dip" dbAc="MI:0465" id="DIP-25N"/>
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                    <secondaryRef db="go" dbAc="MI:0448" id="GO:0005680" secondary="anaphase-promoting complex" version="SP_205"/>
                </xref>
                <interactorType>
                    <names>
                        <shortLabel>protein</shortLabel>
                        <fullName>protein</fullName>
                    </names>
                    <xref>
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                        <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactorType>
                <organism ncbiTaxId="559292">
                    <names>
                        <shortLabel>yeast</shortLabel>
                        <fullName>Saccharomyces cerevisiae</fullName>
                        <alias typeAc="MI:1041" type="synonym">Baker's yeast</alias>
                    </names>
                </organism>
                <sequence>MKFCLYCCHCYIVICGKATHYYKSSKATSNLKSSNRVLMRNPMSPSEQHSQHNSTLAASPFVSNVSAARTQQSLPTDAQNDRLQQPWNRTNTATSPYQSLANSPLIQKLQANIMTPHQPSANSNSNSNSITGNVVNDNNLLASMSKNSMFGSTIPSTLRKVSLQREYKDSVDGVVRDEDNDEDVHNNGDAAANANNDRESKLGHNGPLTTTTLTTTTTATQLDVSELSAIERLRLWRFDALMQHMYRTAEYIADKVYNISNDPDDAFWLGQVYYNNNQYVRAVELITRNNLDGVNILCRYLLGLSFVKLQRFDDALDVIGEYNPFSEDPSTTAANTMSNNGNNSNTSQPVTDGGIKMESSLCFLRGKIYFAQNNFNKARDAFREAILVDIKNFEAFEMLLSKNLLTPQEEWDLFDSLDFKEFGEDKEIMKNLYKINLSKYINTEDITKSNEILAKDYKLADNVDVVRSKVDICYTQCKFNECLELCETVLENDEFNTNILPAYIGCLYELSNKNKLFLLSHRLAETFPKSAITWFSVATYYMSLDRISEAQKYYSKSSILDPSFAAAWLGFAHTYALEGEQDQALTAYSTASRFFPGMHLPKLFLGMQFMAMNSLNLAESYFVLAYDICPNDPLVLNEMGVMYFKKNEFVKAKKYLKKALEVVKDLDPSSRTTISIQLNLGHTYRKLNENEIAIKCFRCVLEKNDKNSEIHCSLGYLYLKTKKLQKAIDHLHKSLYLKPNNSSATALLKNALELNVTLSLDASHPLIDKSNLMSQASKDKASLNKKRSSLTYDPVNMAKRLRTQKEIFDQNNKALRKGGHDSKTGSNNADDDFDADMELE</sequence>
                <attributeList>
                    <attribute name="crc64">A096B34441083488</attribute>
                </attributeList>
            </interactor>
        </interactorList>
        <interactionList>
            <interaction imexId="IM-19991-1" id="678391">
                <names>
                    <shortLabel>cdc16-ama1-1c</shortLabel>
                </names>
                <xref>
                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1553703" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="imex" dbAc="MI:0670" id="IM-19991-1" refType="imex-primary" refTypeAc="MI:0662"/>
                </xref>
                <experimentList>
                    <experimentRef>678388</experimentRef>
                </experimentList>
                <participantList>
                    <participant id="678392">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-1553708" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>678389</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>prey</shortLabel>
                                    <fullName>prey</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="678393">
                                <names>
                                    <shortLabel>c-terminus</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1553709" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>ha tag</shortLabel>
                                        <fullName>ha tag</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">YPYDVPDYA epitope tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">YPYDVPDYA epitope tag</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0520" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456513" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>c-term range</shortLabel>
                                                <fullName>C-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">c-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1039" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929799" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>c-term range</shortLabel>
                                                <fullName>C-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">c-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1039" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929799" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                    <participant id="678394">
                        <names>
                            <shortLabel>N/A</shortLabel>
                        </names>
                        <xref>
                            <primaryRef db="intact" dbAc="MI:0469" id="EBI-1553705" refType="identity" refTypeAc="MI:0356"/>
                        </xref>
                        <interactorRef>678390</interactorRef>
                        <biologicalRole>
                            <names>
                                <shortLabel>unspecified role</shortLabel>
                                <fullName>unspecified role</fullName>
                            </names>
                            <xref>
                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                            </xref>
                        </biologicalRole>
                        <experimentalRoleList>
                            <experimentalRole>
                                <names>
                                    <shortLabel>bait</shortLabel>
                                    <fullName>bait</fullName>
                                </names>
                                <xref>
                                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                </xref>
                            </experimentalRole>
                        </experimentalRoleList>
                        <featureList>
                            <feature id="678395">
                                <names>
                                    <shortLabel>c-terminus</shortLabel>
                                </names>
                                <xref>
                                    <primaryRef db="intact" dbAc="MI:0469" id="EBI-1553706" refType="identity" refTypeAc="MI:0356"/>
                                </xref>
                                <featureType>
                                    <names>
                                        <shortLabel>myc tag</shortLabel>
                                        <fullName>myc tag</fullName>
                                        <alias typeAc="MI:0303" type="go synonym">EUKLISEED epitope tag</alias>
                                        <alias typeAc="MI:1041" type="synonym">EUKLISEED epitope tag</alias>
                                    </names>
                                    <xref>
                                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0522" refType="identity" refTypeAc="MI:0356"/>
                                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456561" refType="identity" refTypeAc="MI:0356"/>
                                    </xref>
                                </featureType>
                                <featureRangeList>
                                    <featureRange>
                                        <startStatus>
                                            <names>
                                                <shortLabel>c-term range</shortLabel>
                                                <fullName>C-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">c-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1039" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929799" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </startStatus>
                                        <endStatus>
                                            <names>
                                                <shortLabel>c-term range</shortLabel>
                                                <fullName>C-terminal range</fullName>
                                                <alias typeAc="MI:1041" type="synonym">c-term range</alias>
                                            </names>
                                            <xref>
                                                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1039" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929799" refType="identity" refTypeAc="MI:0356"/>
                                                <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                                            </xref>
                                        </endStatus>
                                        <isLink>false</isLink>
                                    </featureRange>
                                </featureRangeList>
                            </feature>
                        </featureList>
                    </participant>
                </participantList>
                <interactionType>
                    <names>
                        <shortLabel>physical association</shortLabel>
                        <fullName>physical association</fullName>
                    </names>
                    <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
                    </xref>
                </interactionType>
                <modelled>false</modelled>
                <intraMolecular>false</intraMolecular>
                <negative>false</negative>
                <attributeList>
                    <attribute name="figure legend" nameAc="MI:0599">Fig 3B</attribute>
                </attributeList>
            </interaction>
        </interactionList>
    </entry>
</entrySet>
