UniProt UniProt http://www.uniprot.org davies-2002-4 A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins. mouse-l-929 Mus musculus L929 fibroblasts l-929 L-929 fibroblasts coip coimmunoprecipitation co-immunoprecipitation CoIp immunoprecipitation Co-IP co-immunoprecipitation CoIp immunoprecipitation Co-IP coip western blot western blot Immuno blot Immuno blot Davies TH., Ning YM., Sanchez ER. Cytosolic cell lysates have been treated with 100 nM dexamethasone or RU486 J. Biol. Chem. (0021-9258) 2002 davies-2002-1 A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins. mouse-l-929 Mus musculus L929 fibroblasts l-929 L-929 fibroblasts coip coimmunoprecipitation co-immunoprecipitation CoIp immunoprecipitation Co-IP co-immunoprecipitation CoIp immunoprecipitation Co-IP coip western blot western blot Immuno blot Immuno blot Davies TH., Ning YM., Sanchez ER. Cytosolic cell lysates have been treated with 100 nM dexamethasone or RU486 J. Biol. Chem. (0021-9258) 2002 davies-2002-2 A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins. mouse-l-929 Mus musculus L929 fibroblasts l-929 L-929 fibroblasts coip coimmunoprecipitation co-immunoprecipitation CoIp immunoprecipitation Co-IP co-immunoprecipitation CoIp immunoprecipitation Co-IP coip western blot western blot Immuno blot Immuno blot Davies TH., Ning YM., Sanchez ER. Cytosolic cell lysates have been treated with 100 nM dexamethasone or RU486 J. Biol. Chem. (0021-9258) 2002 davies-2002-3 A new first step in activation of steroid receptors: hormone-induced switching of FKBP51 and FKBP52 immunophilins. mouse-l-929 Mus musculus L929 fibroblasts l-929 L-929 fibroblasts coip coimmunoprecipitation co-immunoprecipitation CoIp immunoprecipitation Co-IP co-immunoprecipitation CoIp immunoprecipitation Co-IP coip western blot western blot Immuno blot Immuno blot Davies TH., Ning YM., Sanchez ER. Cytosolic cell lysates have been treated with 100 nM dexamethasone or RU486 J. Biol. Chem. (0021-9258) 2002 hs90b_mouse Heat shock protein HSP 90-beta Heat shock 84 kDa Tumor-specific transplantation 84 kDa antigen Hsp90ab1 Hsp84 Hsp84-1 Hspcb protein protein mouse Mus musculus Mouse MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKEDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVTAEEPSAAVPDEIPPLEGDEDASRMEEVD gcr_mouse Glucocorticoid receptor Nuclear receptor subfamily 3 group C member 1 Nr3c1 Grl Grl1 protein protein mouse Mus musculus Mouse MDSKESLAPPGRDEVPSSLLGRGRGSVMDLYKTLRGGATVKVSASSPSVAAASQADSKQQRILLDFSKGSASNAQQQQQQQQQQQQQQQQQPQPDLSKAVSLSMGLYMGETETKVMGNDLGYPQQGQLGLSSGETDFRLLEESIANLNRSTSRPENPKSSTPAAGCATPTEKEFPQTHSDPSSEQQNRKSQPGTNGGSVKLYTTDQSTFDILQDLEFSAGSPGKETNESPWRSDLLIDENLLSPLAGEDDPFLLEGDVNEDCKPLILPDTKPKIQDTGDTILSSPSSVALPQVKTEKDDFIELCTPGVIKQEKLGPVYCQASFSGTNIIGNKMSAISVHGVSTSGGQMYHYDMNTASLSQQQDQKPVFNVIPPIPVGSENWNRCQGSGEDNLTSLGAMNFAGRSVFSNGYSSPGMRPDVSSPPSSSSTATGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATAGVSQDTSENANKTIVPAALPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSAWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQASGNLLCFAPDLIINEQRMTLPCMYDQCKHMLFISTELQRLQVSYEEYLCMKTLLLLSSVPKEGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHDVVENLLSYCFQTFLDKSMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK fkbp5_mouse Peptidyl-prolyl cis-trans isomerase FKBP5 FK506-binding protein 5 51 kDa FK506-binding protein Rotamase Fkbp5 Fkbp51 protein protein mouse Mus musculus Mouse MTTDEGTSNNGENPAATMTEQGEDITTKKDRGVLKIVKRVGTSDEAPMFGDKVYVHYKGMLSDGKKFDSSHDRKKPFAFSLGQGQVIKAWDIGVSTMKKGEICHLLCKPEYAYGSAGHLQKIPSNATLFFEIELLDFKGEDLFEDSGVIRRIKRKGEGYSNPNEGATVKVHLEGCCGGRTFDCRDVVFVVGEGEDHDIPIGIDKALVKMQREEQCILYLGPRYGFGEAGKPKFGIDPNAELMYEVTLKSFEKAKESWEMDTKEKLTQAAIVKEKGTVYFKGGKYTQAVIQYRKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYNKAVECCDKALGLDSANEKGLYRRGEAQLLMNDFESAKGDFEKVLAVNPQNRAARLQISMCQRKAKEHNERDRRVYANMFKKFAERDAKEEASKAGSKKAVEGAAGKQHESQAMEEGKAKGHV fkbp4_mouse Peptidyl-prolyl cis-trans isomerase FKBP4 FK506-binding protein 4 HSP-binding immunophilin Rotamase 52 kDa FK506-binding protein FKBP59 Immunophilin FKBP52 Fkbp4 Fkpb52 59 kDa immunophilin protein protein mouse Mus musculus Mouse MTAEEMKAAENGAQSAPLPLEGVDISPKQDEGVLKVIKREGTGTETPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAVATMKVGEVCHITCKPEYAYGAAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIRTRGEGYARPNDGAMVEVALEGYHKDRLFDQRELCFEVGEGESLDLPCGLEEAIQRMEKGEHSIVYLKPSYAFGSVGKERFQIPPHAELRYEVRLKSFEKAKESWEMSSAEKLEQSNIVKERGTAYFKEGKYKQALLQYKKIVSWLEYESSFSGEEMQKVHALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKVLQLYPSNKAAKTQLAVCQQRTRRQLAREKKLYANMFERLAEEEHKVKAEVAAGDHPTDAEMKGERNNVAENQSRVETEA dc1i1_mouse Cytoplasmic dynein 1 intermediate chain 1 Cytoplasmic dynein intermediate chain 1 Dynein intermediate chain 1, cytosolic Dync1i1 Dncic1 Dnci1 protein protein mouse Mus musculus Mouse MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISPEPPLVPTPMSPSSKSVSTPSDAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEEDEEDEEMVEPKIGHDSELENQEKKQETKEAPPRELTEEEKQQILHSEEFLIFFDRTIRVIERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYPELMVASYSNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGTYSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSLDMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVFEGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNSDTEVPTASVAIEGASALNRVRWAQGGKEVAVGDSEGRIWIYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGAVELAA nr3c1-hspcb-2 170428 N/A 170432 unspecified role unspecified role prey prey N/A 170433 unspecified role unspecified role bait bait physical association physical association false false false nr3c1-fkbp5-2 170428 N/A 170434 unspecified role unspecified role prey prey N/A 170433 unspecified role unspecified role bait bait physical association physical association false false false By glucocorticoid hormone treatment nr3c1-fkbp4-3 170428 N/A 170435 unspecified role unspecified role prey prey N/A 170433 unspecified role unspecified role bait bait physical association physical association false false false By glucocorticoid hormone treatment nr3c1-dnci1-2 170428 N/A 170436 unspecified role unspecified role prey prey N/A 170433 unspecified role unspecified role bait bait physical association physical association false false false By glucocorticoid hormone treatment nr3c1-fkbp4-1 170429 N/A 170433 unspecified role unspecified role bait bait N/A 170435 unspecified role unspecified role prey prey physical association physical association false false false By glucocorticoid hormone nr3c1-fkbp5-1 170429 N/A 170433 unspecified role unspecified role bait bait N/A 170434 unspecified role unspecified role prey prey physical association physical association false false false By glucocorticoid hormone nr3c1-hspcb-1 170430 N/A 170432 unspecified role unspecified role prey prey N/A 170433 unspecified role unspecified role bait bait physical association physical association false false false Interaction is not changed by glucocorticoid hormone stimulation nr3c1-dnci1-1 170430 N/A 170436 unspecified role unspecified role prey prey N/A 170433 unspecified role unspecified role bait bait physical association physical association false false false By glucocorticoid hormone treatment nr3c1-fkbp4-2 170431 N/A 170433 unspecified role unspecified role bait bait N/A 170435 unspecified role unspecified role prey prey physical association physical association false false false By glucocorticoid hormone. Most Fkbp4 was bound with 30nM dexamethosone treatment